Yoshino et al., 2017 - Google Patents

DNA methylation changes in intron 1 of Triggering receptor expressed on myeloid cell 2 in Japanese schizophrenia subjects

Yoshino et al., 2017

View HTML
Document ID
7436457563282441494
Author
Yoshino Y
Ozaki Y
Yamazaki K
Sao T
Mori Y
Ochi S
Iga J
Ueno S
Publication year
Publication venue
Frontiers in Neuroscience

External Links

Snippet

A hypothesis for schizophrenia (SCZ) called the “microglia hypothesis” has been suggested. In SCZ, expression of triggering receptor expressed on myeloid cell 2 (TREM2) mRNA is higher in leukocytes than in healthy individuals. Here, the methylation rates of four CpG sites …
Continue reading at www.frontiersin.org (HTML) (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Hybridisation probes
    • C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Similar Documents

Publication Publication Date Title
Gauthier et al. De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia
Vona et al. Genetics of tinnitus: still in its infancy
Walton et al. Correspondence of DNA methylation between blood and brain tissue and its application to schizophrenia research
Labonté et al. Genome-wide epigenetic regulation by early-life trauma
Blumen et al. A rare recessive distal hereditary motor neuropathy with HSJ1 chaperone mutation
Hirata et al. Study of the Catechol‐O‐Methyltransferase (COMT) gene with high aggression in children
Daoud et al. Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis
Gingnell et al. Neuroticism-related personality traits are related to symptom severity in patients with premenstrual dysphoric disorder and to the serotonin transporter gene-linked polymorphism 5-HTTPLPR
Yoshino et al. DNA methylation changes in intron 1 of Triggering receptor expressed on myeloid cell 2 in Japanese schizophrenia subjects
Lin et al. Genetic biomarkers on age-related cognitive decline
Gao et al. DNA methylation and gene expression of matrix metalloproteinase 9 gene in deficit and non-deficit schizophrenia
Singh et al. Differential expression of matrix metalloproteinase-9 gene in wounds of type 2 diabetes mellitus cases with susceptible-1562C> T genotypes and wound severity
Lepeta et al. A normal genetic variation modulates synaptic MMP‐9 protein levels and the severity of schizophrenia symptoms
Stefanis et al. Variation in psychosis gene ZNF804A is associated with a refined schizotypy phenotype but not neurocognitive performance in a large young male population
Mise et al. TOMM40 and APOE gene expression and cognitive decline in Japanese Alzheimer’s disease subjects
Choe et al. Serotonergic genes (5-HTT and HTR1A) and separation life events: gene-by-environment interaction for panic disorder
Guerini et al. Vitamin D receptor polymorphisms associated with autism spectrum disorder
Corrado et al. The length of SNCA Rep1 microsatellite may influence cognitive evolution in Parkinson’s disease
de Nijs et al. DNA methyltransferase isoforms expression in the temporal lobe of epilepsy patients with a history of febrile seizures
França Jr et al. Normal ATXN3 allele but not CHIP polymorphisms modulates age at onset in Machado–Joseph disease
Matsuno et al. A naturally occurring null variant of the NMDA type glutamate receptor NR3B subunit is a risk factor of schizophrenia
Ludwig et al. Influence of CRHR1 polymorphisms and childhood abuse on suicide attempts in affective disorders: a GxE approach
Alfimova et al. Methylation of the reelin gene promoter in peripheral blood and its relationship with the cognitive function of schizophrenia patients
Liu et al. Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population
Ershova et al. Copy number variation of satellite III (1q12) in patients with schizophrenia