Kumar et al., 2001 - Google Patents

Syntheses of curcumin bioconjugates and study of their antibacterial activities against β-lactamase-producing microorganisms

Kumar et al., 2001

Document ID
7051874325315428812
Author
Kumar S
Narain U
Tripathi S
Misra K
Publication year
Publication venue
Bioconjugate Chemistry

External Links

Snippet

In the present study curcumin bioconjugates, viz. di-O-glycinoylcurcumin (I), di-O-glycinoyl-C 4-glycylcurcumin (II), 5 '-deoxy-5 '-curcuminylthymidine (5 '-cur-T)(IV), and 2 '-deoxy-2 '- curcuminyluridine (2 '-cur-U)(V) have been synthesized and characterized by elemental …
Continue reading at pubs.acs.org (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
    • A61K47/48007—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the pharmacologically- or therapeutically-active agent being covalently bound or complexed to a modifying agent
    • A61K47/48023—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the pharmacologically- or therapeutically-active agent being covalently bound or complexed to a modifying agent the modifying agent being an organic compound
    • A61K47/48061—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the pharmacologically- or therapeutically-active agent being covalently bound or complexed to a modifying agent the modifying agent being an organic compound the modifying agent being a heterocyclic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids

Similar Documents

Publication Publication Date Title
Kumar et al. Syntheses of curcumin bioconjugates and study of their antibacterial activities against β-lactamase-producing microorganisms
Hwu et al. Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation
Leu et al. Design and synthesis of water-soluble glucuronide derivatives of camptothecin for cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy (ADEPT)
Qiao et al. Chalcone–benzoxaborole hybrid molecules as potent antitrypanosomal agents
Fenick et al. Doxoform and daunoform: anthracycline− formaldehyde conjugates toxic to resistant tumor cells
Allard et al. Trigocherrin A, the first natural chlorinated daphnane diterpene orthoester from Trigonostemon cherrieri
Urban et al. Triterpenoid pyrazines and benzopyrazines with cytotoxic activity
Lee et al. BODIPY–Coumarin conjugate as an endoplasmic reticulum membrane fluidity sensor and its application to ER stress models
Dunkel et al. Targeted cancer therapy using compounds activated by light
Kobayashi et al. Daphniglaucins A and B, Novel Polycyclic Quaternary Alkaloids from Daphniphyllum g laucescens
Aiello et al. Antitumor effects of two novel naturally occurring terpene quinones isolated from the Mediterranean ascidian Aplidium conicum
Xie et al. Anti-AIDS Agents. 52. Synthesis and Anti-HIV Activity of Hydroxymethyl (3 ‘R, 4 ‘R)-3 ‘, 4 ‘-Di-O-(S)-camphanoyl-(+)-cis-khellactone Derivatives
Xu et al. 6, 7-Seco-ent-kauranoids derived from oridonin as potential anticancer agents
Matos et al. Epoxylathyrol derivatives: Modulation of ABCB1-mediated multidrug resistance in human colon adenocarcinoma and mouse T-lymphoma cells
Chang et al. Cyano Group Removal from Cyano-Promoted Aza-Diels–Alder Adducts: Synthesis and Structure–Activity Relationship of Phenanthroindolizidines and Phenanthroquinolizidines
Tseng et al. Discovery of indeno [1, 2-c] quinoline derivatives as inhibitors of osteoclastogenesis induced by receptor activator of NF-κB Ligand (RANKL)
Chang et al. Design of antineoplastic agents based on the “2-phenylnaphthalene-type” structural pattern. 4. Synthesis and biological activity of 2-chloro-3-(substituted phenoxy)-1, 4-naphthoquinones and related 5, 8-dihydroxy-1, 4-naphthoquinones
Post et al. Doxazolidine, a proposed active metabolite of doxorubicin that cross-links DNA
Naumann et al. SN-38 conjugated gold nanoparticles activated by ewing sarcoma specific mRNAs exhibit in vitro and in vivo efficacy
Zaki et al. Synthesis and antimicrobial activity of novel piperidinyl tetrahydrothieno [2, 3-c] isoquinolines and related heterocycles
Silalai et al. New 1, 2, 3-Triazole-genipin analogues and their anti-alzheimer’s activity
Kim et al. Glycyrrhizin as a nitric oxide regulator in cancer chemotherapy
Gobbi et al. Synthesis and antitumor activity of new derivatives of xanthen-9-one-4-acetic acid
Marchesi et al. Molecular hybridization as a strategy for developing artemisinin-derived anticancer candidates
Zeng et al. Cantharimide and its derivatives from the blister beetle Mylabris phalerata Palla