Hunter et al., 1998 - Google Patents

Bisthiosemicarbazones of 2, 4-pentanedione are pyrazolines

Hunter et al., 1998

Document ID
552437825492170115
Author
Hunter D
McRoberts C
Vittal J
Publication year
Publication venue
Canadian journal of chemistry

External Links

Snippet

Abstract Attempts to prepare 2, 4-bisthiosemicarbamoylpentanediones 1 via literature precedent from 2, 4-pentanedione and three different thiosemicarbazides resulted instead in the formation of cyclic pyrazolines 5. The preparation was attempted with thiosemicarbazide …
Continue reading at search.proquest.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

Similar Documents

Publication Publication Date Title
RU2073005C1 (en) Metal chelate compound
DE69227828T2 (en) Bicyclopolyazamacrocyclophosphonic acid complexes, processes, conjugates and radiopharmaceuticals
AU629178B2 (en) Tri-aza macrocycles and metal complexes thereof
WO1987005030A1 (en) Conjugate compound
HU219485B (en) Process for producing 1,4,7,10-tetraazacyclododecane derivatives, complexes thereof, their antibody conjugates and pharmaceutical compositions containing them and diagnostic compositions containing the complexes and the conjugates
EP2536691B1 (en) Bifunctional chelating agents
Drews et al. Synthesis and biological evaluation of technetium (III) mixed-ligand complexes with high affinity for the cerebral 5-HT1A receptor and the alpha1-adrenergic receptor
Hunter et al. Bisthiosemicarbazones of 2, 4-pentanedione are pyrazolines
HUT67602A (en) Process for producing bicyclo-polyaza-macrocyclo-carboxylic acid complexes, their conjugates and contrast materials containing them
Banerjee et al. A new bifunctional amino acid chelator targeting the glucose transporter
KR102302065B1 (en) A novel radioactive compound for treating melanoma and use thereof
WO2000006542A1 (en) Oxidised sulfurated distamycin derivatives, process for preparing them, and their use as antitumor agents
JP3190615B2 (en) Production method and kit for radiopharmaceuticals
EP1765826B1 (en) Novel antiviral macrocycle derivatives and metal complexes, incorporating bridged macrocycles
JPS61106556A (en) Compound for portion enhancement supply of radiative nuclideand use
EP1084120A1 (en) Cinnamoyl distamycin analogous derivatives, process for their preparation, and their use as antitumor agents
IE912838A1 (en) Reducing chelating agents, their technetium and rhenium¹complexes, process for their production as well as their use¹in diagnosis and treatment
JPH03197468A (en) Bifunctional large cyclic chelate ligand and its preparation
JPH0370700B2 (en)
AU683213B2 (en) Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents
JP2007521337A (en) Pyranone derivatives effective for cancer treatment
Patsis et al. Synthesis, characterization and biodistribution in mice of oxotechnetium (V)(SNS/S) mixed ligand complexes with N, N‐bis (2‐mercaptoethyl)(2‐piperidin‐1‐ylethyl) amine as tridentate ligand
JP2003527378A (en) Bifunctional chelating agent
Chan et al. Synthesis and biodistribution of radioiodinated nicotine analogs
KR100306331B1 (en) Bicyclo polyaza macrocyclocarboxylic acid complex, its conjugate, its preparation method and its use as contrast agent