Abeijón et al., 2006 - Google Patents

Synthesis of two precursors of heterocarbocyclic nucleoside analogues

Abeijón et al., 2006

Document ID
2299530195690646988
Author
Abeijón P
Blanco J
Fernández F
García M
López C
Publication year
Publication venue
European journal of organic chemistry

External Links

Snippet

The racemic heterobicyclic amino alcohols 6 and 7, which are of interest as intermediates in the synthesis of nucleoside analogues with heterobicyclic pseudosugars, were efficiently prepared from 2‐thienylsuccinic acid via methyl 4‐hydroxyimino‐5, 6‐dihydro‐4H …
Continue reading at chemistry-europe.onlinelibrary.wiley.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom

Similar Documents

Publication Publication Date Title
Sharma et al. Synthesis of novel tetrahydroimidazole derivatives and studies for their biological properties
Zhu et al. Highly Efficient Formal [2+ 2+ 2] Strategy for the Rapid Construction of Polycyclic Spiroindolines: A Concise Synthesis of 11‐Demethoxy‐16‐epi‐myrtoidine
CN101583601B (en) Isoquinolone compounds as subtype-selective agonists for melatonin receptors mt1 and mt2
Thompson et al. Synthesis and pharmacological evaluation of a series of dibenzo [a, d] cycloalkenimines as N-methyl-D-aspartate antagonists
Shen et al. Structure and total synthesis of aspernigerin: a novel cytotoxic endophyte metabolite
Eschenbrenner‐Lux et al. Cascade syntheses routes to the centrocountins
Marx et al. A total synthesis of salinosporamide A
Kuehne et al. Application of ferrocenylalkyl chiral auxiliaries to syntheses of indolenine alkaloids: enantioselective syntheses of vincadifformine, ψ-and 20-epi-ψ-vincadifformines, tabersonine, ibophyllidine, and mossambine
AU694212B2 (en) Benzofuran derivatives as d4 receptor antagonists
Taily et al. [3+ 3] annulation via ring opening/cyclization of Donor–Acceptor cyclopropanes with (Un) symmetrical ureas: a quick access to highly functionalized tetrahydropyrimidinones
Wang et al. Stereoselective Intermolecular [4+ 2] Process of N, O‐acetals with Terminal Alkynes for Construction of Functional cis‐Pyrido and Pyrrolo [1, 2‐c][1, 3] oxazin‐1‐ones
Narula et al. Synthesis of α‐Heterocycle Anchored Spirocyclic Azetidin‐2‐ones in a Minute by p‐TSA Catalyzed Cyclocondensation of Azetidin‐2, 3‐diones with Difunctionalized Substrates
CN111423394B (en) Synthesis method of 1,3, 4-oxadiazole heterocyclic compound
Voskressensky et al. A novel synthesis of hexahydroazoninoindoles using activated alkynes in an azepine ring expansion
Tecle et al. Design and Synthesis of m1-Selective Muscarinic Agonists:(R)-(−)-(Z)-1-Azabicyclo [2.2. 1] heptan-3-one, O-(3-(3 ‘-Methoxyphenyl)-2-propynyl)-oxime Maleate (CI-1017), a Functionally m1-Selective Muscarinic Agonist
Abeijón et al. Synthesis of two precursors of heterocarbocyclic nucleoside analogues
Alhamadsheh et al. Total synthesis and selective activity of a new class of conformationally restrained epothilones
Moghaddam et al. The stereoselective synthesis of tetrahydrothiopyrano [2, 3-b] indole skeletons via tandem reaction of indoline-2-thiones to Baylis–Hillman adduct acetates
Kleiner et al. The Discovery and Structure‐Activity Evaluation of (+)‐Floyocidin B and Synthetic Analogs
Fekete et al. A Domino Ring‐Closure Followed by Retro‐Diels–Alder Reaction for the Preparation of Pyrimido [2, 1‐a] isoindole Enantiomers
Cochard et al. Synthesis of Substituted 1, 2, 3, 4‐Tetrahydro‐1‐thiacarbazole and Spiro [pyrrolidinone‐3, 3′‐indolinones] through a Common Intermediate Obtained by Condensation of Indolin‐2‐one,(Aryl) aldehydes, and Meldrum's Acid
Mishra et al. Synthesis and antimicrobial activities of some novel diastereoselective monocyclic cis-β-lactams using 2-ethoxy carbonyl DCPN as a carboxylic acid activator
Mohammadizadeh et al. A novel, convenient, and efficient procedure for the synthesis of spiroisoindoline-1, 5′-oxazolidine derivatives
Halaczkiewicz et al. A Enamide‐Based Diastereoselective Synthesis of Isoindolo [2, 1‐a] quinolin‐11 (5H)‐ones with Three Contiguous Stereogenic Centers
EP0313288A1 (en) Imidazole derivatives, process for their preparation and their use as alpha 2-adreno-receptor antagonists