Okholm et al., 2024 - Google Patents

circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA

Okholm et al., 2024

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Document ID
16814983478556422275
Author
Okholm T
Kamstrup A
Nielsen M
Hollensen A
Graversgaard M
Sørensen M
Kristensen L
Vang S
Park S
Yeo E
Dyrskjøt L
Kjems J
Pedersen J
Damgaard C
Publication year
Publication venue
Elife

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Circular RNAs represent a class of endogenous RNAs that regulate gene expression and influence cell biological decisions with implications for the pathogenesis of several diseases. Here, we disclose a novel gene-regulatory role of circHIPK3 by combining …
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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