Uwatoko et al., 1988 - Google Patents

Low-molecular weight C1q-binding immunoglobulin G in patients with systemic lupus erythematosus consists of autoantibodies to the collagen-like region of C1q.

Uwatoko et al., 1988

View PDF
Document ID
12268390790161521012
Author
Uwatoko S
Mannik M
et al.
Publication year
Publication venue
The Journal of clinical investigation

External Links

Snippet

The majority of C1q-binding IgG in sera of some patients with systemic lupus erythematosus (SLE) cosediments with monomeric IgG. This study was undertaken to provide definitive proof that the low-molecular weight C1q-binding IgG consists of autoantibodies to C1q …
Continue reading at www.jci.org (PDF) (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/564—Immunoassay; Biospecific binding assay for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Similar Documents

Publication Publication Date Title
Uwatoko et al. Low-molecular weight C1q-binding immunoglobulin G in patients with systemic lupus erythematosus consists of autoantibodies to the collagen-like region of C1q.
Simon et al. The cytokeratin filament-aggregating protein filaggrin is the target of the so-called
Panitch et al. CSF antibody to myelin basic protein: measurement in patients with multiple sclerosis and subacute sclerosing panencephalitis
Coulter et al. Enzyme immunoassay for the rapid clinical identification of snake venom
Schlossman et al. Specific fractionation of a population of antidextran molecules with combining sites of various sizes
Siegert et al. IgG and IgA antibodies to the collagen‐like region of C1q in rheumatoid vasculitis
Vallota et al. A serum factor in chronic hypocomplementemic nephritis distinct from immunoglobulins and activating the alternate pathway of complement
Clayman et al. Isolation and characterization of the nephritogenic antigen producing anti-tubular basement membrane disease.
US4544640A (en) Anti immune complex antibody for determining SLE, rheumatoid arthritis or tetanus
Okret et al. Characterization of an antiserum against the glucocorticoid receptor
Fujisawa et al. Platelet-associated antibody to glycoprotein IIb/IIIa from chronic immune thrombocytopenic purpura patients often binds to divalent cation-dependent antigens
Boehm et al. Systemic lupus erythematosus is associated with increased auto‐antibody titers against calreticulin and grp94, but calreticulin is not the Ro/SS‐A antigen
Muller et al. Autoantibodies reacting with poly (ADP-ribose) and with a zinc-finger functional domain of poly (ADP-ribose) polymerase involved in the recognition of damaged DNA
Kleppel et al. Immunochemical studies of the Alport antigen
MARcus et al. The occurrence of cryoproteins in synovial fluid; the association of a complement-fixing activity in rheumatoid synovial fluid with cold-precipitable protein
Fish et al. Detection of Goodpasture antigen in fractions prepared from collagenase digests of human glomerular basement membrane.
Vidal et al. Alternative mechanism of protein A-immunoglobulin interaction the VH-associated reactivity of a monoclonal human IgM.
Uwatoko et al. The location of binding sites on C1q for DNA.
Waldo et al. Mixed IgA-IgG aggregates as a model of immune complexes in IgA nephropathy.
JPS62501563A (en) Proteins characteristic of rheumatoid arthritis
AU679443B2 (en) Methods and reagents for diagnosis of autoantibodies
Parham Changes in conformation with loss of alloantigenic determinants of a histocompatibility antigen (HLA-B7) induced by monoclonal antibodies.
Bartlow et al. Nonimmunoglobulin C3 activating factor in membranoproliferative glomerulonephritis
US5891436A (en) Primary biliary cirrhosis autoantigen and method of use
Ostberg et al. Independent expression of the two HL‐A antigen polypeptide chains