Stanetty et al., 2006 - Google Patents

Synthesis of analogs of the phenylamino-pyrimidine type protein kinase C inhibitor CGP 60474 utilizing a Negishi cross-coupling strategy

Stanetty et al., 2006

Document ID
10939219581424090627
Author
Stanetty P
Röhrling J
Schnürch M
Mihovilovic M
Publication year
Publication venue
Tetrahedron

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Snippet

Analogs of 3-{4-[2-(3-chlorophenylamino)-pyrimidin-4-yl]-pyridin-2-yl-amino}-propanol (CGP 60474) were synthesized as useful models for the evaluation of structure–activity relationships of phenylamino-pyrimidine-type protein kinase C inhibitors. The approach …
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