ZA895175B - Piperidine derivatives - Google Patents
Piperidine derivativesInfo
- Publication number
- ZA895175B ZA895175B ZA895175A ZA895175A ZA895175B ZA 895175 B ZA895175 B ZA 895175B ZA 895175 A ZA895175 A ZA 895175A ZA 895175 A ZA895175 A ZA 895175A ZA 895175 B ZA895175 B ZA 895175B
- Authority
- ZA
- South Africa
- Prior art keywords
- chem
- formula
- group
- piperidine derivatives
- substituents
- Prior art date
Links
- 150000003053 piperidines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000004899 motility Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- -1 substituents hydrogen Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888816365A GB8816365D0 (en) | 1988-07-08 | 1988-07-08 | Therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA895175B true ZA895175B (en) | 1991-02-27 |
Family
ID=10640168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA895175A ZA895175B (en) | 1988-07-08 | 1989-07-07 | Piperidine derivatives |
Country Status (28)
Country | Link |
---|---|
US (1) | US5089505A (zh) |
EP (1) | EP0350309B1 (zh) |
JP (2) | JPH0739388B2 (zh) |
KR (1) | KR930002728B1 (zh) |
CN (1) | CN1022914C (zh) |
AT (1) | ATE82262T1 (zh) |
AU (1) | AU602453B2 (zh) |
CA (1) | CA1336833C (zh) |
DD (1) | DD284011A5 (zh) |
DE (1) | DE68903437T2 (zh) |
DK (1) | DK337589A (zh) |
EG (1) | EG18853A (zh) |
ES (1) | ES2052917T3 (zh) |
FI (1) | FI94241C (zh) |
GB (1) | GB8816365D0 (zh) |
GR (1) | GR3006595T3 (zh) |
HU (1) | HUT50771A (zh) |
IE (1) | IE63438B1 (zh) |
IL (1) | IL90792A0 (zh) |
MX (1) | MX16728A (zh) |
MY (1) | MY106976A (zh) |
NO (1) | NO892828L (zh) |
NZ (1) | NZ229865A (zh) |
PL (2) | PL161887B1 (zh) |
PT (1) | PT91081B (zh) |
RU (2) | RU1838307C (zh) |
YU (1) | YU135389A (zh) |
ZA (1) | ZA895175B (zh) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5231104A (en) * | 1988-07-08 | 1993-07-27 | Pfizer Inc. | 1-arylethyl-3-substituted piperidines |
GB9000301D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Piperidine & pyrrolidine derivatives |
GB9208230D0 (en) * | 1992-04-14 | 1992-05-27 | Pfizer Ltd | Treatment of delayed gastric emptying |
US5340826A (en) * | 1993-02-04 | 1994-08-23 | Pfizer Inc. | Pharmaceutical agents for treatment of urinary incontinence |
GB9400600D0 (en) * | 1994-01-14 | 1994-03-09 | Pfizer Ltd | Treatment of motion seckness |
US6492400B1 (en) | 1998-12-18 | 2002-12-10 | Bristol-Myers Squibb Pharma Company | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
US6525069B1 (en) | 1998-12-18 | 2003-02-25 | Bristol-Myers Squibb Pharma Co. | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
US6331541B1 (en) | 1998-12-18 | 2001-12-18 | Soo S. Ko | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
EP1161240B1 (en) * | 1998-12-18 | 2005-08-17 | Bristol-Myers Squibb Pharma Company | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
AU2482100A (en) * | 1998-12-18 | 2000-07-03 | Du Pont Pharmaceuticals Company | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
US6897234B2 (en) | 1999-12-17 | 2005-05-24 | Bristol-Myers Squibb Pharma Company | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
IL153123A0 (en) | 2000-06-30 | 2003-06-24 | Bristol Myers Squibb Co | N-ureidoheterocycloalkyl-piperidine derivatives and pharmaceutical compositions containing the same |
CA2422055A1 (en) * | 2000-09-11 | 2002-03-21 | Sepracor, Inc. | Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission) |
US6508872B2 (en) * | 2001-02-26 | 2003-01-21 | Hewlett-Packard Company | Lightfast additive molecule for inkjet ink |
US20090005309A1 (en) * | 2007-05-18 | 2009-01-01 | Auspex Pharmaceuticals, Inc. | Substituted piperidines |
EP2578569B1 (en) * | 2010-05-27 | 2015-10-28 | ASKA Pharmaceutical Co., Ltd. | Heterocyclic ring compound and h1 receptor antagonist |
CN107129453B (zh) * | 2016-02-26 | 2019-10-11 | 中国科学院大连化学物理研究所 | 化合物、毒蕈碱m受体拮抗剂、组合物及应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA541598A (en) * | 1957-05-28 | Levy Joseph | N-substituted-4-benzhydryl etherpiperidines and method for obtaining the same | |
GB688345A (en) * | 1951-02-19 | 1953-03-04 | Greenwood And Hughes Ltd | Improvements in sanitary liquid traps |
US2745837A (en) * | 1954-01-21 | 1956-05-15 | Schering Corp | Benzhydryl ethers of alkyl piperidinols |
GB780027A (en) * | 1955-01-20 | 1957-07-31 | Schering Corp | 3-piperidyl ethers and thioethers |
US2974146A (en) * | 1956-02-24 | 1961-03-07 | Lakeside Lab Inc | 3-piperidyl benzhydryl ethers |
NL237664A (zh) * | 1959-04-01 |
-
1988
- 1988-07-08 GB GB888816365A patent/GB8816365D0/en active Pending
-
1989
- 1989-06-29 IL IL90792A patent/IL90792A0/xx not_active IP Right Cessation
- 1989-07-05 MY MYPI89000908A patent/MY106976A/en unknown
- 1989-07-06 CA CA000604882A patent/CA1336833C/en not_active Expired - Fee Related
- 1989-07-06 PT PT91081A patent/PT91081B/pt not_active IP Right Cessation
- 1989-07-06 ES ES89306881T patent/ES2052917T3/es not_active Expired - Lifetime
- 1989-07-06 DD DD89330509A patent/DD284011A5/de not_active IP Right Cessation
- 1989-07-06 US US07/376,263 patent/US5089505A/en not_active Expired - Fee Related
- 1989-07-06 EP EP89306881A patent/EP0350309B1/en not_active Expired - Lifetime
- 1989-07-06 DE DE8989306881T patent/DE68903437T2/de not_active Expired - Fee Related
- 1989-07-06 EG EG32789A patent/EG18853A/xx active
- 1989-07-06 YU YU01353/89A patent/YU135389A/xx unknown
- 1989-07-06 AT AT89306881T patent/ATE82262T1/de not_active IP Right Cessation
- 1989-07-07 PL PL89280474A patent/PL161887B1/pl unknown
- 1989-07-07 RU SU894614534A patent/RU1838307C/ru active
- 1989-07-07 DK DK337589A patent/DK337589A/da not_active Application Discontinuation
- 1989-07-07 PL PL89283209A patent/PL162318B1/pl unknown
- 1989-07-07 NO NO89892828A patent/NO892828L/no unknown
- 1989-07-07 HU HU893449A patent/HUT50771A/hu unknown
- 1989-07-07 KR KR1019890009671A patent/KR930002728B1/ko not_active IP Right Cessation
- 1989-07-07 ZA ZA895175A patent/ZA895175B/xx unknown
- 1989-07-07 MX MX1672889A patent/MX16728A/es unknown
- 1989-07-07 FI FI893326A patent/FI94241C/fi not_active IP Right Cessation
- 1989-07-07 NZ NZ229865A patent/NZ229865A/en unknown
- 1989-07-07 AU AU37971/89A patent/AU602453B2/en not_active Ceased
- 1989-07-07 IE IE220289A patent/IE63438B1/en not_active IP Right Cessation
- 1989-07-08 CN CN89104933A patent/CN1022914C/zh not_active Expired - Fee Related
- 1989-07-10 JP JP1177854A patent/JPH0739388B2/ja not_active Expired - Fee Related
-
1990
- 1990-09-17 RU SU904831151A patent/RU1836364C/ru active
-
1992
- 1992-12-21 GR GR920403003T patent/GR3006595T3/el unknown
-
1994
- 1994-07-26 JP JP6173882A patent/JPH07157469A/ja active Pending
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