WO2003072708A3 - Pluripotent cells comprising allogenic nucleus and mitochondria - Google Patents

Pluripotent cells comprising allogenic nucleus and mitochondria Download PDF

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Publication number
WO2003072708A3
WO2003072708A3 PCT/US2003/004868 US0304868W WO03072708A3 WO 2003072708 A3 WO2003072708 A3 WO 2003072708A3 US 0304868 W US0304868 W US 0304868W WO 03072708 A3 WO03072708 A3 WO 03072708A3
Authority
WO
WIPO (PCT)
Prior art keywords
mitochondria
pluripotent cells
allogenic
nucleus
cells
Prior art date
Application number
PCT/US2003/004868
Other languages
French (fr)
Other versions
WO2003072708A2 (en
Inventor
Michael D West
Original Assignee
Advanced Cell Tech Inc
Michael D West
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Cell Tech Inc, Michael D West filed Critical Advanced Cell Tech Inc
Priority to AU2003217569A priority Critical patent/AU2003217569A1/en
Publication of WO2003072708A2 publication Critical patent/WO2003072708A2/en
Publication of WO2003072708A3 publication Critical patent/WO2003072708A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/106—Primate
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/107—Rabbit
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
    • C12N2517/04—Cells produced using nuclear transfer

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Allochimeric ES cells are provided having nuclei from one individual of a species and mitochondria from a individual of the same species. The ES cells can be used for differentiation into differentiated cell types for therapy or for studying various developmental processes in forming embryos and differentiation.
PCT/US2003/004868 2002-02-21 2003-02-21 Pluripotent cells comprising allogenic nucleus and mitochondria WO2003072708A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003217569A AU2003217569A1 (en) 2002-02-21 2003-02-21 Pluripotent cells comprising allogenic nucleus and mitochondria

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35785402P 2002-02-21 2002-02-21
US60/357,854 2002-02-21

Publications (2)

Publication Number Publication Date
WO2003072708A2 WO2003072708A2 (en) 2003-09-04
WO2003072708A3 true WO2003072708A3 (en) 2004-02-05

Family

ID=27765949

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/004868 WO2003072708A2 (en) 2002-02-21 2003-02-21 Pluripotent cells comprising allogenic nucleus and mitochondria

Country Status (2)

Country Link
AU (1) AU2003217569A1 (en)
WO (1) WO2003072708A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011197A (en) * 1997-03-06 2000-01-04 Infigen, Inc. Method of cloning bovines using reprogrammed non-embryonic bovine cells
US6235970B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts, Amherst Campus CICM cells and non-human mammalian embryos prepared by nuclear transfer of a proliferating differentiated cell or its nucleus
US20010012513A1 (en) * 1996-08-19 2001-08-09 University Of Massachusetts Embryonic or stem-like cell lines produced by cross species nuclear transplantation
WO2001079445A2 (en) * 2000-04-14 2001-10-25 Advanced Cell Technology, Inc. Pluripotent cells comprising allogenic nucleus and mitochondria

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010012513A1 (en) * 1996-08-19 2001-08-09 University Of Massachusetts Embryonic or stem-like cell lines produced by cross species nuclear transplantation
US6235970B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts, Amherst Campus CICM cells and non-human mammalian embryos prepared by nuclear transfer of a proliferating differentiated cell or its nucleus
US6011197A (en) * 1997-03-06 2000-01-04 Infigen, Inc. Method of cloning bovines using reprogrammed non-embryonic bovine cells
WO2001079445A2 (en) * 2000-04-14 2001-10-25 Advanced Cell Technology, Inc. Pluripotent cells comprising allogenic nucleus and mitochondria

Also Published As

Publication number Publication date
AU2003217569A8 (en) 2003-09-09
WO2003072708A2 (en) 2003-09-04
AU2003217569A1 (en) 2003-09-09

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