WO1999056304A8 - Apparatus and method for creating a continuous electrospray of a sample for mass spectrometric analysis - Google Patents

Apparatus and method for creating a continuous electrospray of a sample for mass spectrometric analysis

Info

Publication number
WO1999056304A8
WO1999056304A8 PCT/US1999/008899 US9908899W WO9956304A8 WO 1999056304 A8 WO1999056304 A8 WO 1999056304A8 US 9908899 W US9908899 W US 9908899W WO 9956304 A8 WO9956304 A8 WO 9956304A8
Authority
WO
WIPO (PCT)
Prior art keywords
mass spectrometric
ion spray
spray body
creating
sample
Prior art date
Application number
PCT/US1999/008899
Other languages
French (fr)
Other versions
WO1999056304A3 (en
WO1999056304A9 (en
WO1999056304A2 (en
Inventor
Scott Geromanos
Paul Tempst
Original Assignee
Sloan Kettering Inst Cancer
Scott Geromanos
Paul Tempst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sloan Kettering Inst Cancer, Scott Geromanos, Paul Tempst filed Critical Sloan Kettering Inst Cancer
Priority to AU38660/99A priority Critical patent/AU3866099A/en
Publication of WO1999056304A2 publication Critical patent/WO1999056304A2/en
Publication of WO1999056304A3 publication Critical patent/WO1999056304A3/en
Publication of WO1999056304A9 publication Critical patent/WO1999056304A9/en
Publication of WO1999056304A8 publication Critical patent/WO1999056304A8/en

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165—Electrospray ionisation

Landscapes

  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

Apparatus and method to form continuous electrospray of an analyte for mass spectrometric analaysis, wherein the analyte is stored in a resealably sealable container connected to a chamber of an ion spray body, and in fluid registry therewith, and a pressure fluid means connected to the container and in fluid connection therewith, so that pressure in the container drives the analyte to the chamber of the ion spray body where it is ionized, and then expelled through a needle connected to the chamber of the ion spray body and in fluid registry therewith, wherein the needle is downstream from the ion spray body.
PCT/US1999/008899 1998-04-24 1999-04-23 Apparatus and method for creating a continuous electrospray of a sample for mass spectrometric analysis WO1999056304A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU38660/99A AU3866099A (en) 1998-04-24 1999-04-23 Apparatus and method for creating a continuous electrospray of a sample for massspectrometric analysis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8298898P 1998-04-24 1998-04-24
US60/082,988 1998-04-24

Publications (4)

Publication Number Publication Date
WO1999056304A2 WO1999056304A2 (en) 1999-11-04
WO1999056304A3 WO1999056304A3 (en) 2000-01-20
WO1999056304A9 WO1999056304A9 (en) 2000-04-27
WO1999056304A8 true WO1999056304A8 (en) 2001-02-08

Family

ID=22174721

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/008899 WO1999056304A2 (en) 1998-04-24 1999-04-23 Apparatus and method for creating a continuous electrospray of a sample for mass spectrometric analysis

Country Status (2)

Country Link
AU (1) AU3866099A (en)
WO (1) WO1999056304A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE02744176T1 (en) * 2001-05-24 2005-01-13 New Objective, Inc., Woburn METHOD AND DEVICE FOR ELECTROSPRAY WITH FEEDBACK CONTROL
EP2850643B1 (en) * 2012-05-18 2020-01-22 DH Technologies Development Pte. Ltd. Method and system for introducing make-up flow in an electrospray ion source system
US10718745B2 (en) 2015-11-09 2020-07-21 Thermo Finnigan Llc Systems and methods for ionization
US20220139690A1 (en) * 2019-02-01 2022-05-05 Dh Technologies Development Pte. Ltd. System for Monitoring and Controlling the Composition of Charged Droplets for Optimum Ion Emission

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5572023A (en) * 1995-05-30 1996-11-05 Board Of Regents, The University Of Texas System Electrospray methods and apparatus for trace analysis

Also Published As

Publication number Publication date
WO1999056304A3 (en) 2000-01-20
AU3866099A (en) 1999-11-16
WO1999056304A9 (en) 2000-04-27
WO1999056304A2 (en) 1999-11-04

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