US3804098A - Body implantable lead - Google Patents

Body implantable lead Download PDF

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Publication number
US3804098A
US3804098A US00244841A US24484172A US3804098A US 3804098 A US3804098 A US 3804098A US 00244841 A US00244841 A US 00244841A US 24484172 A US24484172 A US 24484172A US 3804098 A US3804098 A US 3804098A
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body member
electrical conductor
insulating
central portion
conductor means
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US00244841A
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H Friedman
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Medtronic Inc
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Medtronic Inc
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Priority to US00244841A priority Critical patent/US3804098A/en
Priority to CA168,739A priority patent/CA995763A/en
Priority to GB1829673A priority patent/GB1423261A/en
Priority to JP48043546A priority patent/JPS4920985A/ja
Priority to AR247610A priority patent/AR200997A1/en
Priority to NL7305359A priority patent/NL7305359A/xx
Priority to DE2319499A priority patent/DE2319499A1/en
Priority to FR7313959A priority patent/FR2180907B1/fr
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056—Transvascular endocardial electrode systems

Definitions

  • ABSTRACT A body-implantable, bipolar lead for insertion in and guidance through a body vessel to a desired location inside the body.
  • the lead comprises a pair of electrical conductors adapted to be connected at their proximal end to a source of electrical energy.
  • the conductors are substantially covered with a material substantially inert to body fluids and tissue.
  • Tip and proximal electrodes spaced from one another are formed as an integral part of the corresponding conductor by at least a portion of the conductor projecting radially through the outer surface of the covering material and being at least partially exposed.
  • endocardial leads One problem which has existed with endocardial leads is the relationship of the electrical conductors and the electrodes.
  • the tip and proximal electrodes have been metal rings which are located on the outside of the inert material covering the conductors and bonded to the rings by soldering, welding, adhesive bonding or other bonding techniques.
  • the difficulty with this is that with the contraction of the heart the bond between the conductors and electrodes is subjected to continual stress and thus apt to break.
  • the covering material is apt to be broken by the edges of the rings thereby permitting body fluids to find their way inside the lead.
  • the present invention overcomes the disadvantages of the prior art by eliminating the use of metal rings for the tip and proximal electrodes. Also, the need for a bond between the conductor and the electrode is eliminated. The problem of leakage of body fluids into the lead over time is also substantially eliminated. The overall construction of the lead of the present invention is much more durable and reliable than those of the prior art.
  • a body-implantable, bipolar, endocardial lead comprising a pair of electrical conductors, means adapted to connect the proximal ends of the conductors to a source of electrical energy, means for permitting the lead to be insertedin and guided through a body vessel to a desired location inside the body, means for substantially covering the conductors with a material substantially inert to body fluids and tissue.
  • the improvement being the formation ofthe tip and proximal electrodes as an integral part of the corresponding conductor by at least a portion of the conductor projecting through the outer surface of the covering means and being at least partially exposed to thereby form the tip and proximal electrodes respectively.
  • the exposed portion of each conductor is wrapped at least one turn around the covering means.
  • FIGURE shows a lead in accordance with the present invention.
  • FIGURE shows a body-implantable, bipolar, endocardial lead 10.
  • Lead 10 comprises a pair of electri- O cal conductors l2 and 14 embedded in a covering 16.
  • Conductors 12 and 14 may, for example, be of the configuration and construction of the lead described in U.S. Pat. No. 3,572,344. However, it should be understood that any conductor configuration and construction compatible with body fluids and tissue may be used in the present invention.
  • Covering 16 is made of a material which is substantially inert to body fluids and tissue, such as, for example, silicone rubber. Covering 16 is split into two legs 18 and 20 near the proximal end of lead 10.
  • Conductors l2 and 14 are connected to metal connectors 22 and 24 respectively which connectors are adapted to be connected to a source of electrical energy such as a pulse. generator of a cardiac pacemaker.
  • Conductors 12 and 14 and connectors 22 and 24 are made of materials which are substantially inert to body fluids and tissue and may, for example, be platinum or a platinum iridium alloy.
  • a'closely wound helical coil spring 26 which is open at its proximal end 28 and crimped at its distal end 30.
  • Spring 26 defines a lumen into which a stylet (not shown) may be inserted. Insertion of a stylet makes lead 10 sufficiently rigid so that it may be inserted in and guided through a body vessel to a desired location inside the body. Once lead 10 is in its desired location inside the body, the stylet may be withdrawn.
  • Electrode 36 is the proximal electrode and is formed as an integral part of conductor 14. Proximal electrode 36 is formed by conductor 14 projecting through the outer surface of covering 16 at point 40 and being closely wrapped in a helical configuration toward electrode 34 for several'turns about covering 16. The turns of electrode 36 are terminated with the distal end of conductor 14 being embedded in covering 16. The turns of electrode 36 are partially embedded in covering 16 so as to help maintain the turns in fixed position and prevent them from moving.
  • lead 10 When lead 10 is used as an enclocardial lead for a pacemaker system, lead 10 is inserted transvenously and electrode 34 is wedged in the apex of the right ventricle. Although lead 10 has been described for use in conjunction with a cardiac pacemaker system, it should be understood that lead 10 may be used in other intravascular applications, such as, for example, as a lead for a cardioversion or defibrillation system.
  • lead has been shown and described as a bipolar lead, it could also have only one electrode for use with a monopolar system.
  • tip and proximal electrodes 34 and 36 have been shown in a wrapped configuration around covering material 16, they could assume other configurations.
  • An example of another configuration would be to have the electrodes just sections of conductors 12 and 14 partially embedded in and partially exposed along a section of covering material 16.
  • a body implantable lead which comprises:
  • At least one electrical conductor means is provided
  • insulating means encapsulating and electrically insulating said conductor means, said insulating means being of a material which is substantially inert to body fluids and tissues;
  • At least one electrode means partially embedded within the surface of said insulating means and helically wrapped and electrically exposed for at least one entire turn around the periphery of said insulating means for providing an electrical contact at all situs of said electrode means at the periphery of said insulating means, said electrode means being unitary with said conductor means, the terminus of said electrode means being totally embedded within said insulating means.
  • a body implantable lead which comprises:
  • a body member having an elongated central portion of substantially uniform cross section, a connector portion on the proximal end of said central protion and a tip portion on the distal end of said central portion.
  • said body member being formed of an electrically insulating material which is substantially inert to body fluids and tissues;
  • first electrical conducting means embedded within said body member and originating at said body member connector portion for connection to an external device, said first electrical conductor means extending from said body member connector portion through said body member central portion to a point adjacent said body member tip portion whereat said first electrical conductor means projects through the surface of the body member central portion and is wrapped at least once around the periphery of said body member central portion while being partially embedded within its surface such that said first electrical conductor means is electrically exposed only at the location of said wrapping and is so exposed around the entire periphery of said body member central portion, the terminus of said first electrical conductor means being totally embedded within said body member; and
  • second electrical conductor means embedded within said body member and electrically insulated from said first electrical conductor means, said second electrical conductor means originating at said body member connector portion for connection to an external electrical device and extending from said body member connector portion through said body member central portion to a point spaced from the point at which said first electrical conductor means projects through the surface of said body member central portion whereat said second electrical conductor means projects through the surface of said body member central portion and is wrapped at least once around the periphery of said body member central portion while being partially embedded within its surface such that said second electrical conductor means is electrically exposed only at the location of said wrapping and is so exposed around the entire periphery of said body member central portion, the terminus of said second electrical conductor means being totally embedded within said body member.
  • a body implantable lead which comprises:
  • insulating means encapsulating said first and second electrical conductor means and electrically insulating them from each other, said insulating means being of a material which is substantially inert to body fluids and tissues;
  • first electrode means unitary with said first electrical conductor means partially embedded within the surface of said insulating means and helically wrapped and electrically exposed for at least one entire turn around the periphery of said insulating means for providing an electrical contact at all situs of said electrode means at the periphery of said insulating means, the terminus of said first electrode means being totally embedded within said insulating means;
  • second electrode means unitary with said second electrical conductor means spaced from said first electrode means and partially embedded within the surface of said insulating means, said second electrode means being helically wrapped and electrically exposed for at least one entire turn around the periphery of said insulating means for providing an electrical contact at all situs of said second electrode means at the periphery of said insulating means, the terminus of said second electrode means being totally embedded within said insulating means.
  • said guiding means including means encapsulated in said insulating means and defining a lumin therethrough.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Insulated Conductors (AREA)

Abstract

A body-implantable, bipolar lead for insertion in and guidance through a body vessel to a desired location inside the body. The lead comprises a pair of electrical conductors adapted to be connected at their proximal end to a source of electrical energy. The conductors are substantially covered with a material substantially inert to body fluids and tissue. Tip and proximal electrodes spaced from one another are formed as an integral part of the corresponding conductor by at least a portion of the conductor projecting radially through the outer surface of the covering material and being at least partially exposed.

Description

United States Patent Friedman Apr. 16, 1974 BODY IMPLANTABLE LEAD Prima ExaminerRichard A. Gaudet 75 l t 1 n G. F ed N B ht 1 men or ix n ew mg on Assistant Examiner-Lee S. Cohen Attorney, Agent, or Firm-Irving S. 'Rappaport; Wayne [73] Assignee: Medronic, Inc., Minneapolis, Minn. A, Siv rt n [22] Filed: Apr. 17, 1972 App]. No.2 244,841
[52] US. Cl 128/404, 128/419 P [51] Int. Cl A61n l/04 [58] Field of Search 128/418, 404, 419 P, 2.1 E,
[5 6] References Cited UNITED STATES PATENTS 3,729,008 4/1973 Berkovits 128/418 3,348,548 10/1967 3,416,533 12/1968 3,472,234 10/1969 3,485,247 12/1969 3,664,347 5/1972 Harmjanz ..128/404 [5 7] ABSTRACT A body-implantable, bipolar lead for insertion in and guidance through a body vessel to a desired location inside the body. The lead comprises a pair of electrical conductors adapted to be connected at their proximal end to a source of electrical energy. The conductors are substantially covered with a material substantially inert to body fluids and tissue. Tip and proximal electrodes spaced from one another are formed as an integral part of the corresponding conductor by at least a portion of the conductor projecting radially through the outer surface of the covering material and being at least partially exposed.
9 Claims, 1 Drawing Figure PATENTEUAPR 16 1974 BODY IMPLANTABLE LEAD BACKGROUND OF THE INVENTION smyocardial or endocardialfor delivering the stimulating pulses from the pulse generator to the patients heart. Myocardial leads have electrodes which are secured directly into cardiac tissue. Endocardial leads are passed intravenously to the heart and the electrodes are positioned so that the tip electrode is lodged in the apex of the right ventricle of the heart.
One problem which has existed with endocardial leads is the relationship of the electrical conductors and the electrodes. In prior art endocardial leads, the tip and proximal electrodes have been metal rings which are located on the outside of the inert material covering the conductors and bonded to the rings by soldering, welding, adhesive bonding or other bonding techniques. The difficulty with this is that with the contraction of the heart the bond between the conductors and electrodes is subjected to continual stress and thus apt to break. Also the covering material is apt to be broken by the edges of the rings thereby permitting body fluids to find their way inside the lead.
The present invention overcomes the disadvantages of the prior art by eliminating the use of metal rings for the tip and proximal electrodes. Also, the need for a bond between the conductor and the electrode is eliminated. The problem of leakage of body fluids into the lead over time is also substantially eliminated. The overall construction of the lead of the present invention is much more durable and reliable than those of the prior art.
SUMMARY OF THE INVENTION Theabove advantages, features and objects of the present invention, as well as others, are accomplished by providing in a body-implantable, bipolar, endocardial lead comprising a pair of electrical conductors, means adapted to connect the proximal ends of the conductors to a source of electrical energy, means for permitting the lead to be insertedin and guided through a body vessel to a desired location inside the body, means for substantially covering the conductors with a material substantially inert to body fluids and tissue. and tip and proximal electrodes spaced from one another and connected to the distal ends of the corresponding conductors, the improvement being the formation ofthe tip and proximal electrodes as an integral part of the corresponding conductor by at least a portion of the conductor projecting through the outer surface of the covering means and being at least partially exposed to thereby form the tip and proximal electrodes respectively. In the preferred embodiment the exposed portion of each conductor is wrapped at least one turn around the covering means.
Other advantages. features and objects of the present invention will hereinafter become more fully apparent from the following description of the drawing, which illustrates a preferred embodiment of the present invention.
BRIEF DESCRIPTION OF THE DRAWING The FIGURE shows a lead in accordance with the present invention.
DESCRIPTION OF THE PREFERRED EMBODIMENT The FIGURE shows a body-implantable, bipolar, endocardial lead 10. Lead 10 comprises a pair of electri- O cal conductors l2 and 14 embedded in a covering 16.
Conductors 12 and 14 may, for example, be of the configuration and construction of the lead described in U.S. Pat. No. 3,572,344. However, it should be understood that any conductor configuration and construction compatible with body fluids and tissue may be used in the present invention. Covering 16 is made of a material which is substantially inert to body fluids and tissue, such as, for example, silicone rubber. Covering 16 is split into two legs 18 and 20 near the proximal end of lead 10. Conductors l2 and 14 are connected to metal connectors 22 and 24 respectively which connectors are adapted to be connected to a source of electrical energy such as a pulse. generator of a cardiac pacemaker. Conductors 12 and 14 and connectors 22 and 24 are made of materials which are substantially inert to body fluids and tissue and may, for example, be platinum or a platinum iridium alloy.
Also embedded in the covering 16 and extending from the juncture oflegs l8 and 20 to close to the distal end of lead 10 is a'closely wound helical coil spring 26 which is open at its proximal end 28 and crimped at its distal end 30. Spring 26 defines a lumen into which a stylet (not shown) may be inserted. Insertion of a stylet makes lead 10 sufficiently rigid so that it may be inserted in and guided through a body vessel to a desired location inside the body. Once lead 10 is in its desired location inside the body, the stylet may be withdrawn.
covering 16. The turns of electrode 34 are partially embedded in covering 16 so as to help maintain the turns in fixed position and prevent them from moving. Electrode 36 is the proximal electrode and is formed as an integral part of conductor 14. Proximal electrode 36 is formed by conductor 14 projecting through the outer surface of covering 16 at point 40 and being closely wrapped in a helical configuration toward electrode 34 for several'turns about covering 16. The turns of electrode 36 are terminated with the distal end of conductor 14 being embedded in covering 16. The turns of electrode 36 are partially embedded in covering 16 so as to help maintain the turns in fixed position and prevent them from moving.
When lead 10 is used as an enclocardial lead for a pacemaker system, lead 10 is inserted transvenously and electrode 34 is wedged in the apex of the right ventricle. Although lead 10 has been described for use in conjunction with a cardiac pacemaker system, it should be understood that lead 10 may be used in other intravascular applications, such as, for example, as a lead for a cardioversion or defibrillation system.
Although lead has been shown and described as a bipolar lead, it could also have only one electrode for use with a monopolar system. Also, although the tip and proximal electrodes 34 and 36 have been shown in a wrapped configuration around covering material 16, they could assume other configurations. An example of another configuration would be to have the electrodes just sections of conductors 12 and 14 partially embedded in and partially exposed along a section of covering material 16.
It should be understood, of course, that the foregoing disclosure relates to only a preferred embodiment of the invention and that numerous modifications or alterations may be made therein without departing from the spirit and scope of the invention as set forth in the appended claims.
I claim:
1. A body implantable lead which comprises:
at least one electrical conductor means:
means for connecting said electrical conductor means to a source of electrical energy;
insulating means encapsulating and electrically insulating said conductor means, said insulating means being of a material which is substantially inert to body fluids and tissues; and
at least one electrode means partially embedded within the surface of said insulating means and helically wrapped and electrically exposed for at least one entire turn around the periphery of said insulating means for providing an electrical contact at all situs of said electrode means at the periphery of said insulating means, said electrode means being unitary with said conductor means, the terminus of said electrode means being totally embedded within said insulating means.
2. A body implantable lead which comprises:
a body member having an elongated central portion of substantially uniform cross section, a connector portion on the proximal end of said central protion and a tip portion on the distal end of said central portion. said body member being formed of an electrically insulating material which is substantially inert to body fluids and tissues;
first electrical conducting means embedded within said body member and originating at said body member connector portion for connection to an external device, said first electrical conductor means extending from said body member connector portion through said body member central portion to a point adjacent said body member tip portion whereat said first electrical conductor means projects through the surface of the body member central portion and is wrapped at least once around the periphery of said body member central portion while being partially embedded within its surface such that said first electrical conductor means is electrically exposed only at the location of said wrapping and is so exposed around the entire periphery of said body member central portion, the terminus of said first electrical conductor means being totally embedded within said body member; and
second electrical conductor means embedded within said body member and electrically insulated from said first electrical conductor means, said second electrical conductor means originating at said body member connector portion for connection to an external electrical device and extending from said body member connector portion through said body member central portion to a point spaced from the point at which said first electrical conductor means projects through the surface of said body member central portion whereat said second electrical conductor means projects through the surface of said body member central portion and is wrapped at least once around the periphery of said body member central portion while being partially embedded within its surface such that said second electrical conductor means is electrically exposed only at the location of said wrapping and is so exposed around the entire periphery of said body member central portion, the terminus of said second electrical conductor means being totally embedded within said body member.
3. The body implantable lead of claim 2 wherein the terminus of each of said first and second electrical conductor means are embedded within said body member at a point distal to the point at which the respective lead projects through the surface of said body member central portion.
4. The body implantable lead of claim 2 wherein said first and second electrical conductor means are helically wrapped around the periphery of said body member central portion in a direction away from said body member connector portion.
5. A body implantable lead which comprises:
first electrical conductor means;
second electrical conductor means;
means for connecting said first and second conductor means to a source of electrical energy;
insulating means encapsulating said first and second electrical conductor means and electrically insulating them from each other, said insulating means being of a material which is substantially inert to body fluids and tissues;
first electrode means unitary with said first electrical conductor means partially embedded within the surface of said insulating means and helically wrapped and electrically exposed for at least one entire turn around the periphery of said insulating means for providing an electrical contact at all situs of said electrode means at the periphery of said insulating means, the terminus of said first electrode means being totally embedded within said insulating means; and
second electrode means unitary with said second electrical conductor means spaced from said first electrode means and partially embedded within the surface of said insulating means, said second electrode means being helically wrapped and electrically exposed for at least one entire turn around the periphery of said insulating means for providing an electrical contact at all situs of said second electrode means at the periphery of said insulating means, the terminus of said second electrode means being totally embedded within said insulating means. I
6. The body implantable lead of claim 5 wherein said I insulating means covering said first and second electrical conductor means has a substantially uniform cross section in the region at which said first and second electrode means are partially embedded therein.
said guiding means including means encapsulated in said insulating means and defining a lumin therethrough.
9. The body implantable lead of claim 5 wherein the helix formed by said first and second electrode means extend away from the respective unitary electrical conductor means.

Claims (9)

1. A body implantable lead which comprises: at least one electrical conductor means: means for connecting said electrical conductor means to a source of electrical energy; insulating means encapsulating and electrically insulating said conductor means, said insulating means being of a material which is substantially inert to body fluids and tissues; and at least one electrode means partially embedded within the surface of said insulating means and helically wrapped and electrically exposed for at least one entire turn around the periphery of said insulating means for providing an electrical contact at all situs of said electrode means at the periphery of said insulating means, said electrode means being unitary with said conductor means, the terminus of said electrode means being totally embedded within said insulating means.
2. A body implantable lead which comprises: a body member having an elongated central portion of substantially uniform cross section, a connector portion on the proximal end of said central protion and a tip portion on the distal end of said central portion, said body member being formed of an electrically insulating material which is substantially inert to body fluids and tissues; first electrical conducting means embedded within said body member and originating at said body member connector portion for connection to an external device, said first electrical conductor means extending from said body member connector portion through said body member central portion to a point adjacent said body member tip portion whereat said first electrical conductor means projects through the surface of the body member central portion and is wrapped at least once around the periphery of said body member central portion while being partially embedded within its surface such that said first electrical conductor means is electrically exposed only at the location of said wrapping and is so exposed around the entire periphery of said body member central portion, the terminus of said first electrical conductor means being totally embedded within said body member; and second electrical conductor means embedded within said body member and electrically insulated from said first electrical conductor means, said second electrical conductor means originating at said body member connector portion for connection to an external electrical device and extending from said body member connector portion through said body member central portion to a point spaced from the point at which said first electrical conductor means projects through the surface of said body member central portion whereat said second electrical conductor means projects through the surface of said body member central portion and is wrapped at least once around the periphery of said body member central portion while being partially embedded within its surface such that said second electrical conductor means is electrically exposed only at the location of said wrapping and is so exposed around the entire periphery of said body member central portion, the terminus of said second electrical conductor means being totally embedded within said body member.
3. The body implantable lead of claim 2 wherein the terminus of each of said first and second electrical conductor means are embedded within said body member at a point distal to the point at which the respective lead projects through the surface of said Body member central portion.
4. The body implantable lead of claim 2 wherein said first and second electrical conductor means are helically wrapped around the periphery of said body member central portion in a direction away from said body member connector portion.
5. A body implantable lead which comprises: first electrical conductor means; second electrical conductor means; means for connecting said first and second conductor means to a source of electrical energy; insulating means encapsulating said first and second electrical conductor means and electrically insulating them from each other, said insulating means being of a material which is substantially inert to body fluids and tissues; first electrode means unitary with said first electrical conductor means partially embedded within the surface of said insulating means and helically wrapped and electrically exposed for at least one entire turn around the periphery of said insulating means for providing an electrical contact at all situs of said electrode means at the periphery of said insulating means, the terminus of said first electrode means being totally embedded within said insulating means; and second electrode means unitary with said second electrical conductor means spaced from said first electrode means and partially embedded within the surface of said insulating means, said second electrode means being helically wrapped and electrically exposed for at least one entire turn around the periphery of said insulating means for providing an electrical contact at all situs of said second electrode means at the periphery of said insulating means, the terminus of said second electrode means being totally embedded within said insulating means.
6. The body implantable lead of claim 5 wherein said insulating means covering said first and second electrical conductor means has a substantially uniform cross section in the region at which said first and second electrode means are partially embedded therein.
7. The body implantable lead of claim 6 wherein the helix formed by said first and second electrode means extend away from their respective unitary electrical conductor means.
8. The body implantable lead of claim 7 further comprising means extending substantially the entire length of said insulating means for guiding the lead through a body vessel and into a desired location inside the body, said guiding means including means encapsulated in said insulating means and defining a lumin therethrough.
9. The body implantable lead of claim 5 wherein the helix formed by said first and second electrode means extend away from the respective unitary electrical conductor means.
US00244841A 1972-04-17 1972-04-17 Body implantable lead Expired - Lifetime US3804098A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
US00244841A US3804098A (en) 1972-04-17 1972-04-17 Body implantable lead
CA168,739A CA995763A (en) 1972-04-17 1973-04-13 Body implantable lead
GB1829673A GB1423261A (en) 1972-04-17 1973-04-16 Body implantable lead
AR247610A AR200997A1 (en) 1972-04-17 1973-04-17 FLEXIBLE PROBE IMPLANTABLE IN THE BODY
JP48043546A JPS4920985A (en) 1972-04-17 1973-04-17
NL7305359A NL7305359A (en) 1972-04-17 1973-04-17
DE2319499A DE2319499A1 (en) 1972-04-17 1973-04-17 IMPLANTABLE LEAD ARRANGEMENT
FR7313959A FR2180907B1 (en) 1972-04-17 1973-04-17

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JP (1) JPS4920985A (en)
AR (1) AR200997A1 (en)
CA (1) CA995763A (en)
DE (1) DE2319499A1 (en)
FR (1) FR2180907B1 (en)
GB (1) GB1423261A (en)
NL (1) NL7305359A (en)

Cited By (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3981309A (en) * 1974-12-23 1976-09-21 American Optical Corporation Patient stimulating pacer electrode
US4144891A (en) * 1977-04-20 1979-03-20 Medtronic, Inc. Heart stimulator lead set
US4161952A (en) * 1977-11-01 1979-07-24 Mieczyslaw Mirowski Wound wire catheter cardioverting electrode
US4172451A (en) * 1978-04-06 1979-10-30 Medical Evaluation Devices And Instruments Corp. Intracardial electrode and a method of manufacture thereof
DE3043189A1 (en) * 1980-11-15 1982-06-03 Peter Dr.-Ing. 7889 Grenzach-Wyhlen Osypka Compact heart pacemaker electrode - has coaxial windings for separate electrode pole conductors
EP0109178A2 (en) * 1982-10-14 1984-05-23 Baxter International Inc. Flexible tip cardiac pacing catheter
US4458695A (en) * 1982-07-16 1984-07-10 Cordis Corporation Multipolar electrode assembly for pacing lead
US4574807A (en) * 1984-03-02 1986-03-11 Carl Hewson Method and apparatus for pacing the heart employing external and internal electrodes
US4603705A (en) * 1984-05-04 1986-08-05 Mieczyslaw Mirowski Intravascular multiple electrode unitary catheter
US4614192A (en) * 1982-04-21 1986-09-30 Mieczyslaw Mirowski Implantable cardiac defibrillator employing bipolar sensing and telemetry means
US4683890A (en) * 1985-12-23 1987-08-04 Brunswick Manufacturing Co., Inc. Method and apparatus for controlled breathing employing internal and external electrodes
US4930521A (en) * 1989-03-17 1990-06-05 Metzger William T Variable stiffness esophageal catheter
US5376109A (en) * 1992-06-16 1994-12-27 Siemens Aktiengesellschaft Medical electrode device
US5417208A (en) * 1993-10-12 1995-05-23 Arrow International Investment Corp. Electrode-carrying catheter and method of making same
US5476497A (en) * 1991-01-09 1995-12-19 Ann Mirowski Oval electrode lead body
US5554178A (en) * 1993-02-22 1996-09-10 Cardiac Pacemakers, Inc. Metalized implantable cardiac electrode
US5755757A (en) * 1996-05-01 1998-05-26 Teague; Thomas Wade Apparatus for localized neutralization of poison
US5843148A (en) * 1996-09-27 1998-12-01 Medtronic, Inc. High resolution brain stimulation lead and method of use
US5871529A (en) * 1997-01-16 1999-02-16 Cardiac Pacemakers, Inc. Electrode for high impedance heart stimulation
US5913887A (en) * 1996-03-01 1999-06-22 Cardiac Pacemakers, Inc. Device for the transvenous cardioversion of atrial fibrillation or atrial flutter including three coil electrodes
US5916243A (en) * 1992-11-24 1999-06-29 Cardiac Pacemakers, Inc. Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation
US6085119A (en) * 1998-07-22 2000-07-04 Cardiac Pacemakers, Inc. Single pass endocardial lead for multi-site atrial pacing
US6152954A (en) * 1998-07-22 2000-11-28 Cardiac Pacemakers, Inc. Single pass lead having retractable, actively attached electrode for pacing and sensing
US6212434B1 (en) 1998-07-22 2001-04-03 Cardiac Pacemakers, Inc. Single pass lead system
US6253111B1 (en) 1998-03-30 2001-06-26 Pacesetter, Inc. Multi-conductor lead
US6321122B1 (en) 1998-07-22 2001-11-20 Cardiac Pacemakers, Inc. Single pass defibrillation/pacing lead with passively attached electrode for pacing and sensing
US6363286B1 (en) * 1999-09-24 2002-03-26 Cardiac Pacemakers, Inc. High impedance electrode assembly
US6463334B1 (en) 1998-11-02 2002-10-08 Cardiac Pacemakers, Inc. Extendable and retractable lead
US20020198570A1 (en) * 1997-08-26 2002-12-26 Puskas John D. Apparatus for indirectly stimulating the vagus nerve with an electrical field
US6501994B1 (en) 1997-12-24 2002-12-31 Cardiac Pacemakers, Inc. High impedance electrode tip
US20030093136A1 (en) * 2001-11-09 2003-05-15 Osypka Thomas P. Cardiac lead with steroid eluting ring
US20040024422A1 (en) * 2000-09-26 2004-02-05 Hill Michael R.S. Method and system for sensing cardiac contractions during a medical procedure
US20040111118A1 (en) * 2000-09-26 2004-06-10 Hill Michael R.S. Method and system for spinal cord stimulation prior to and during a medical procedure
US20040172075A1 (en) * 1996-04-30 2004-09-02 Shafer Lisa L. Method and system for vagal nerve stimulation with multi-site cardiac pacing
US20040186517A1 (en) * 1996-04-30 2004-09-23 Hill Michael R.S. Method and system for nerve stimulation prior to and during a medical procedure
US20040199209A1 (en) * 2003-04-07 2004-10-07 Hill Michael R.S. Method and system for delivery of vasoactive drugs to the heart prior to and during a medical procedure
US20050096707A1 (en) * 2000-09-26 2005-05-05 Medtronic, Inc. Method and system for monitoring and controlling systemic and pulmonary circulation during a medical procedure
US6983185B2 (en) 1998-07-22 2006-01-03 Cardiac Pacemakers, Inc. Lead with terminal connector assembly
US20060089692A1 (en) * 2004-10-21 2006-04-27 Medtronic, Inc. Implantable medical lead with stylet guide tube
US20060089691A1 (en) * 2004-10-21 2006-04-27 Medtronic, Inc. Implantable medical lead with axially oriented coiled wire conductors
US20060089697A1 (en) * 2004-10-21 2006-04-27 Medtronic, Inc. Implantable medical lead
US20060142812A1 (en) * 2004-12-20 2006-06-29 Action Medical, Inc. Pacemaker which reestablishes or keeps the physiological electric conduction of the heart and a method of application
US7225019B2 (en) 1996-04-30 2007-05-29 Medtronic, Inc. Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
US7245973B2 (en) 2003-12-23 2007-07-17 Cardiac Pacemakers, Inc. His bundle mapping, pacing, and injection lead
US20080319499A1 (en) * 2004-12-20 2008-12-25 Qingsheng Zhu Devices and Methods for Steering Electrical Stimulation in Cardiac Rhythm Management
US20090005846A1 (en) * 2004-12-20 2009-01-01 Qingsheng Zhu Methods, Devices and Systems for Cardiac Rhythm Management Using an Electrode Arrangement
US20100004708A1 (en) * 1996-04-30 2010-01-07 Medtronic, Inc. Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
US7840278B1 (en) 1999-06-25 2010-11-23 Puskas John D Devices and methods for vagus nerve stimulation
WO2010148376A1 (en) * 2009-06-19 2010-12-23 Medtronic, Inc. Helical electrode arrangements for medical leads
US8290586B2 (en) 2004-12-20 2012-10-16 Cardiac Pacemakers, Inc. Methods, devices and systems for single-chamber pacing using a dual-chamber pacing device
US8406868B2 (en) 2010-04-29 2013-03-26 Medtronic, Inc. Therapy using perturbation and effect of physiological systems
US8509920B2 (en) 2009-06-19 2013-08-13 Medtronic, Inc. Electrode arrangements for medical lead
US8538521B2 (en) 2004-12-20 2013-09-17 Cardiac Pacemakers, Inc. Systems, devices and methods for monitoring efficiency of pacing
US8543203B2 (en) 2004-12-20 2013-09-24 Cardiac Pacemakers, Inc. Endocardial pacing devices and methods useful for resynchronization and defibrillation
US8565880B2 (en) 2010-04-27 2013-10-22 Cardiac Pacemakers, Inc. His-bundle capture verification and monitoring
US8620425B2 (en) 2010-04-29 2013-12-31 Medtronic, Inc. Nerve signal differentiation in cardiac therapy
US8639327B2 (en) 2010-04-29 2014-01-28 Medtronic, Inc. Nerve signal differentiation in cardiac therapy
US8688234B2 (en) 2008-12-19 2014-04-01 Cardiac Pacemakers, Inc. Devices, methods, and systems including cardiac pacing
US8706223B2 (en) 2011-01-19 2014-04-22 Medtronic, Inc. Preventative vagal stimulation
US8718763B2 (en) 2011-01-19 2014-05-06 Medtronic, Inc. Vagal stimulation
US8725259B2 (en) 2011-01-19 2014-05-13 Medtronic, Inc. Vagal stimulation
US8781583B2 (en) 2011-01-19 2014-07-15 Medtronic, Inc. Vagal stimulation
US8781582B2 (en) 2011-01-19 2014-07-15 Medtronic, Inc. Vagal stimulation
US8880169B2 (en) 2004-12-20 2014-11-04 Cardiac Pacemakers, Inc. Endocardial pacing relating to conduction abnormalities
US8929993B2 (en) 2009-06-19 2015-01-06 Medtronic, Inc. Electrode arrangements for suborbital foramen medical lead
US9242088B2 (en) 2013-11-22 2016-01-26 Simon Fraser University Apparatus and methods for assisted breathing by transvascular nerve stimulation
US9364659B1 (en) 2015-04-27 2016-06-14 Dantam K. Rao Smart lead for deep brain stimulation
US10039920B1 (en) 2017-08-02 2018-08-07 Lungpacer Medical, Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10293164B2 (en) 2017-05-26 2019-05-21 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
US10391314B2 (en) 2014-01-21 2019-08-27 Lungpacer Medical Inc. Systems and related methods for optimization of multi-electrode nerve pacing
US10406367B2 (en) 2013-06-21 2019-09-10 Lungpacer Medical Inc. Transvascular diaphragm pacing system and methods of use
US10512772B2 (en) 2012-03-05 2019-12-24 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus and methods
US10561843B2 (en) 2007-01-29 2020-02-18 Lungpacer Medical, Inc. Transvascular nerve stimulation apparatus and methods
US10940308B2 (en) 2017-08-04 2021-03-09 Lungpacer Medical Inc. Systems and methods for trans-esophageal sympathetic ganglion recruitment
US10987511B2 (en) 2018-11-08 2021-04-27 Lungpacer Medical Inc. Stimulation systems and related user interfaces
US11357979B2 (en) 2019-05-16 2022-06-14 Lungpacer Medical Inc. Systems and methods for sensing and stimulation
US11771900B2 (en) 2019-06-12 2023-10-03 Lungpacer Medical Inc. Circuitry for medical stimulation systems
US11883658B2 (en) 2017-06-30 2024-01-30 Lungpacer Medical Inc. Devices and methods for prevention, moderation, and/or treatment of cognitive injury
US12029903B2 (en) 2017-12-11 2024-07-09 Lungpacer Medical Inc. Systems and methods for strengthening a respiratory muscle

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2305168A1 (en) * 1975-03-24 1976-10-22 Ieram Sarl Patient respiration stimulation system - uses catheters with electrodes near phrenic nerves thrust into subclavian vein to receive electrical impulses
US4026303A (en) * 1975-11-17 1977-05-31 Vitatron Medical B.V. Endocardial pacing electrode
DE3046667A1 (en) * 1980-12-11 1982-07-22 Peter Dr. 7850 Lörrach Osypka Bipolar or multipolar electrode for cardiac stimulator - has electrode conductors are wound to form multiple helix with same exterior dia.
DE3107128C2 (en) * 1981-02-26 1984-07-05 Heinze, Roland, Dipl.-Ing., 8000 München Control circuit for adapting the stimulation frequency of a cardiac pacemaker to the load on a patient
JPH064097B2 (en) * 1985-03-20 1994-01-19 ブランズウィック・バイオメディカル・テクノロジーズ・インコーポレーテッド Heart pacing device
DE3530269C2 (en) * 1985-08-22 1997-01-16 Biotronik Mess & Therapieg Implantable indifferent electrode for cardiac stimulation

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3348548A (en) * 1965-04-26 1967-10-24 William M Chardack Implantable electrode with stiffening stylet
US3416533A (en) * 1966-05-20 1968-12-17 Gen Electric Conductive catheter
US3472234A (en) * 1967-08-15 1969-10-14 Gen Electric Body organ electrode
US3485247A (en) * 1965-08-16 1969-12-23 Electro Catheter Corp Cardiac catheterization apparatus and method
US3664347A (en) * 1968-07-27 1972-05-23 Dietrich Harmjanz Electric heart stimulation method and electrode
US3729008A (en) * 1970-12-28 1973-04-24 American Optical Corp Electrode for atrial pacing with curved end for atrial wall engagement

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1955517B2 (en) * 1968-11-18 1972-01-05 Medtronic Inc., Minneapolis, Minn. (V.St.A.) ELECTRODE ARRANGEMENT FOR IMPLANTATION IN THE BODY

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3348548A (en) * 1965-04-26 1967-10-24 William M Chardack Implantable electrode with stiffening stylet
US3485247A (en) * 1965-08-16 1969-12-23 Electro Catheter Corp Cardiac catheterization apparatus and method
US3416533A (en) * 1966-05-20 1968-12-17 Gen Electric Conductive catheter
US3472234A (en) * 1967-08-15 1969-10-14 Gen Electric Body organ electrode
US3664347A (en) * 1968-07-27 1972-05-23 Dietrich Harmjanz Electric heart stimulation method and electrode
US3729008A (en) * 1970-12-28 1973-04-24 American Optical Corp Electrode for atrial pacing with curved end for atrial wall engagement

Cited By (165)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3981309A (en) * 1974-12-23 1976-09-21 American Optical Corporation Patient stimulating pacer electrode
US4144891A (en) * 1977-04-20 1979-03-20 Medtronic, Inc. Heart stimulator lead set
US4161952A (en) * 1977-11-01 1979-07-24 Mieczyslaw Mirowski Wound wire catheter cardioverting electrode
US4172451A (en) * 1978-04-06 1979-10-30 Medical Evaluation Devices And Instruments Corp. Intracardial electrode and a method of manufacture thereof
DE3043189A1 (en) * 1980-11-15 1982-06-03 Peter Dr.-Ing. 7889 Grenzach-Wyhlen Osypka Compact heart pacemaker electrode - has coaxial windings for separate electrode pole conductors
US4614192A (en) * 1982-04-21 1986-09-30 Mieczyslaw Mirowski Implantable cardiac defibrillator employing bipolar sensing and telemetry means
US4458695A (en) * 1982-07-16 1984-07-10 Cordis Corporation Multipolar electrode assembly for pacing lead
EP0109178A3 (en) * 1982-10-14 1984-12-27 American Hospital Supply Corporation Flexible tip cardiac pacing catheter
EP0109178A2 (en) * 1982-10-14 1984-05-23 Baxter International Inc. Flexible tip cardiac pacing catheter
US4574807A (en) * 1984-03-02 1986-03-11 Carl Hewson Method and apparatus for pacing the heart employing external and internal electrodes
US4603705A (en) * 1984-05-04 1986-08-05 Mieczyslaw Mirowski Intravascular multiple electrode unitary catheter
US4683890A (en) * 1985-12-23 1987-08-04 Brunswick Manufacturing Co., Inc. Method and apparatus for controlled breathing employing internal and external electrodes
US4930521A (en) * 1989-03-17 1990-06-05 Metzger William T Variable stiffness esophageal catheter
WO1990011104A1 (en) * 1989-03-17 1990-10-04 Arzco Medical Electronics, Inc. Variable stiffness esophageal catheter
EP0473598A1 (en) * 1989-03-17 1992-03-11 Arzco Medical Electronics, Inc. Variable stiffness esophageal catheter
EP0473598A4 (en) * 1989-03-17 1992-09-30 Arzco Medical Electronics, Inc. Variable stiffness esophageal catheter
US5476497A (en) * 1991-01-09 1995-12-19 Ann Mirowski Oval electrode lead body
US5376109A (en) * 1992-06-16 1994-12-27 Siemens Aktiengesellschaft Medical electrode device
US6026332A (en) * 1992-11-24 2000-02-15 Cardiac Pacemakers, Inc. Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation
US6038483A (en) * 1992-11-24 2000-03-14 Cardiac Pacemakers, Inc. Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation
US6032079A (en) * 1992-11-24 2000-02-29 Cardiac Pacemakers, Inc. Implantable conformal coil electrode with multiple conductive elements for cardioversion and defibrillation
US6152955A (en) * 1992-11-24 2000-11-28 Cardiac Pacemakers, Inc. Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation
US5916243A (en) * 1992-11-24 1999-06-29 Cardiac Pacemakers, Inc. Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation
US5554178A (en) * 1993-02-22 1996-09-10 Cardiac Pacemakers, Inc. Metalized implantable cardiac electrode
US5417208A (en) * 1993-10-12 1995-05-23 Arrow International Investment Corp. Electrode-carrying catheter and method of making same
USRE35924E (en) * 1993-10-12 1998-10-13 Arrow International Investment Corp. Electrode-carrying catheter and method of making same
US5913887A (en) * 1996-03-01 1999-06-22 Cardiac Pacemakers, Inc. Device for the transvenous cardioversion of atrial fibrillation or atrial flutter including three coil electrodes
US7366574B2 (en) 1996-03-01 2008-04-29 Cardiac Pacemakers, Inc. Device for the transvenous cardioversion of atrial fibrillation or atrial flutter
US6438416B1 (en) 1996-03-01 2002-08-20 Cardiac Pacemakers, Inc. Device for the transvenous cardioversion of atrial fibrillation or atrial flutter including three coil electrodes
US6041256A (en) * 1996-03-01 2000-03-21 Cardiac Pacemakers, Inc. Device for the transvenous cardioversion of atrial fibrillation or atrial flutter
US20040193240A1 (en) * 1996-03-01 2004-09-30 Cardiac Pacemakers, Inc. Device for the transvenous cardioversion of atrial fibrillation or atrial flutter
US6741894B2 (en) 1996-03-01 2004-05-25 Cardiac Pacemakers, Inc. Device for the transvenous cardioversion of atrial fibrillation or atrial flutter
US8036741B2 (en) 1996-04-30 2011-10-11 Medtronic, Inc. Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
US7269457B2 (en) 1996-04-30 2007-09-11 Medtronic, Inc. Method and system for vagal nerve stimulation with multi-site cardiac pacing
US7225019B2 (en) 1996-04-30 2007-05-29 Medtronic, Inc. Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
US7184829B2 (en) 1996-04-30 2007-02-27 Medtronic, Inc. Method and system for nerve stimulation prior to and during a medical procedure
US20040186517A1 (en) * 1996-04-30 2004-09-23 Hill Michael R.S. Method and system for nerve stimulation prior to and during a medical procedure
US20040172075A1 (en) * 1996-04-30 2004-09-02 Shafer Lisa L. Method and system for vagal nerve stimulation with multi-site cardiac pacing
US20100004708A1 (en) * 1996-04-30 2010-01-07 Medtronic, Inc. Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
US5755757A (en) * 1996-05-01 1998-05-26 Teague; Thomas Wade Apparatus for localized neutralization of poison
US5843148A (en) * 1996-09-27 1998-12-01 Medtronic, Inc. High resolution brain stimulation lead and method of use
US5871529A (en) * 1997-01-16 1999-02-16 Cardiac Pacemakers, Inc. Electrode for high impedance heart stimulation
US20020198570A1 (en) * 1997-08-26 2002-12-26 Puskas John D. Apparatus for indirectly stimulating the vagus nerve with an electrical field
US7340299B2 (en) 1997-08-26 2008-03-04 Puskas John D Methods of indirectly stimulating the vagus nerve to achieve controlled asystole
US7142910B2 (en) 1997-08-26 2006-11-28 Emory University Methods of indirectly stimulating the vagus nerve with an electrical field
US20050143412A1 (en) * 1997-08-26 2005-06-30 Puskas John D. Methods of indirectly stimulating the vagus nerve with an electrical field
US20040059383A1 (en) * 1997-08-26 2004-03-25 Puskas John D. Methods of indirectly stimulating the vagus nerve with an electrical field
US7310552B2 (en) 1997-08-26 2007-12-18 Puskas John D Apparatus for indirectly stimulating the vagus nerve with an electrical field
US6501994B1 (en) 1997-12-24 2002-12-31 Cardiac Pacemakers, Inc. High impedance electrode tip
US20040133259A1 (en) * 1997-12-24 2004-07-08 Cardiac Pacemakers, Inc. High impedance electrode tip
US6253111B1 (en) 1998-03-30 2001-06-26 Pacesetter, Inc. Multi-conductor lead
US7392095B2 (en) 1998-07-22 2008-06-24 Cardiac Pacemakers, Inc. Extendable and retractable lead having a snap-fit terminal connector
US8209035B2 (en) 1998-07-22 2012-06-26 Cardiac Pacemakers, Inc. Extendable and retractable lead having a snap-fit terminal connector
US6321122B1 (en) 1998-07-22 2001-11-20 Cardiac Pacemakers, Inc. Single pass defibrillation/pacing lead with passively attached electrode for pacing and sensing
US6152954A (en) * 1998-07-22 2000-11-28 Cardiac Pacemakers, Inc. Single pass lead having retractable, actively attached electrode for pacing and sensing
US6085119A (en) * 1998-07-22 2000-07-04 Cardiac Pacemakers, Inc. Single pass endocardial lead for multi-site atrial pacing
US20080262587A1 (en) * 1998-07-22 2008-10-23 Cardiac Pacemakers, Inc Extendable and retractable lead having a snap-fit terminal connector
US7774934B2 (en) 1998-07-22 2010-08-17 Cardiac Pacemakers, Inc. Method for making a terminal connector
US6915169B2 (en) 1998-07-22 2005-07-05 Cardiac Pacemakers, Inc. Extendable and retractable lead having a snap-fit terminal connector
US6983185B2 (en) 1998-07-22 2006-01-03 Cardiac Pacemakers, Inc. Lead with terminal connector assembly
US8285398B2 (en) 1998-07-22 2012-10-09 Cardiac Pacemakers, Inc. Lead with terminal connector assembly
US6505082B1 (en) 1998-07-22 2003-01-07 Cardiac Pacemakers, Inc. Single pass lead system
US6212434B1 (en) 1998-07-22 2001-04-03 Cardiac Pacemakers, Inc. Single pass lead system
US6345204B1 (en) 1998-07-22 2002-02-05 Cardiac Pacemakers, Inc. Single pass lead having retractable, actively attached electrode for pacing and sensing
US6463334B1 (en) 1998-11-02 2002-10-08 Cardiac Pacemakers, Inc. Extendable and retractable lead
US7840278B1 (en) 1999-06-25 2010-11-23 Puskas John D Devices and methods for vagus nerve stimulation
US20020058981A1 (en) * 1999-09-24 2002-05-16 Cardiac Pacemakers, Inc. High impedance electrode assembly
US6889092B2 (en) 1999-09-24 2005-05-03 Cardiac Pacemakers, Inc. High impedance electrode assembly
US6363286B1 (en) * 1999-09-24 2002-03-26 Cardiac Pacemakers, Inc. High impedance electrode assembly
US20070208381A1 (en) * 2000-09-26 2007-09-06 Medtronic, Inc. Method and system for spinal cord stimulation prior to and during a medical procedure
US20050096707A1 (en) * 2000-09-26 2005-05-05 Medtronic, Inc. Method and system for monitoring and controlling systemic and pulmonary circulation during a medical procedure
US7184828B2 (en) 2000-09-26 2007-02-27 Medtronic, Inc. Method and system for spinal cord stimulation prior to and during a medical procedure
US20040111118A1 (en) * 2000-09-26 2004-06-10 Hill Michael R.S. Method and system for spinal cord stimulation prior to and during a medical procedure
US20040024422A1 (en) * 2000-09-26 2004-02-05 Hill Michael R.S. Method and system for sensing cardiac contractions during a medical procedure
US7187980B2 (en) 2001-11-09 2007-03-06 Oscor Inc. Cardiac lead with steroid eluting ring
US6671562B2 (en) 2001-11-09 2003-12-30 Oscor Inc. High impedance drug eluting cardiac lead
US20030093136A1 (en) * 2001-11-09 2003-05-15 Osypka Thomas P. Cardiac lead with steroid eluting ring
US20040199209A1 (en) * 2003-04-07 2004-10-07 Hill Michael R.S. Method and system for delivery of vasoactive drugs to the heart prior to and during a medical procedure
US8078287B2 (en) 2003-12-23 2011-12-13 Cardiac Pacemakers, Inc. His bundle mapping, pacing, and injection lead
US7245973B2 (en) 2003-12-23 2007-07-17 Cardiac Pacemakers, Inc. His bundle mapping, pacing, and injection lead
US7761170B2 (en) 2004-10-21 2010-07-20 Medtronic, Inc. Implantable medical lead with axially oriented coiled wire conductors
US7831311B2 (en) 2004-10-21 2010-11-09 Medtronic, Inc. Reduced axial stiffness implantable medical lead
US20060089692A1 (en) * 2004-10-21 2006-04-27 Medtronic, Inc. Implantable medical lead with stylet guide tube
US20060089691A1 (en) * 2004-10-21 2006-04-27 Medtronic, Inc. Implantable medical lead with axially oriented coiled wire conductors
US20060089697A1 (en) * 2004-10-21 2006-04-27 Medtronic, Inc. Implantable medical lead
US9008768B2 (en) 2004-12-20 2015-04-14 Cardiac Pacemakers, Inc. Methods, devices and systems for cardiac rhythm management using an electrode arrangement
US8346358B2 (en) 2004-12-20 2013-01-01 Cardiac Pacemakers, Inc. Pacemaker which reestablishes or keeps the physiological electric conduction of the heart and a method of application
US8880169B2 (en) 2004-12-20 2014-11-04 Cardiac Pacemakers, Inc. Endocardial pacing relating to conduction abnormalities
US20060142812A1 (en) * 2004-12-20 2006-06-29 Action Medical, Inc. Pacemaker which reestablishes or keeps the physiological electric conduction of the heart and a method of application
US20090005846A1 (en) * 2004-12-20 2009-01-01 Qingsheng Zhu Methods, Devices and Systems for Cardiac Rhythm Management Using an Electrode Arrangement
US8838238B2 (en) 2004-12-20 2014-09-16 Cardiac Pacemakers, Inc. Ventricular pacing
US20090093861A1 (en) * 2004-12-20 2009-04-09 Action Medical, Inc. Methods for treating the physiological electric conduction of the heart
US8285376B2 (en) 2004-12-20 2012-10-09 Cardiac Pacemakers, Inc. Ventricular pacing
US20090093859A1 (en) * 2004-12-20 2009-04-09 Action Medical, Inc. Apparatus for treating the physiological electric conduction of the heart
US8290586B2 (en) 2004-12-20 2012-10-16 Cardiac Pacemakers, Inc. Methods, devices and systems for single-chamber pacing using a dual-chamber pacing device
US8326423B2 (en) 2004-12-20 2012-12-04 Cardiac Pacemakers, Inc. Devices and methods for steering electrical stimulation in cardiac rhythm management
US8903489B2 (en) 2004-12-20 2014-12-02 Cardiac Pacemakers, Inc. Methods, devices and systems for single-chamber pacing using a dual-chamber pacing device
US9031648B2 (en) 2004-12-20 2015-05-12 Cardiac Pacemakers, Inc. Endocardial pacing devices and methods useful for resynchronization and defibrillation
US8825159B2 (en) 2004-12-20 2014-09-02 Cardiac Pacemakers, Inc. Devices and methods for steering electrical stimulation in cardiac rhythm management
US8423139B2 (en) 2004-12-20 2013-04-16 Cardiac Pacemakers, Inc. Methods, devices and systems for cardiac rhythm management using an electrode arrangement
US8428715B2 (en) 2004-12-20 2013-04-23 Cardiac Pacemakers, Inc. Methods for treating the physiological electric conduction of the heart
US8437848B2 (en) 2004-12-20 2013-05-07 Cardiac Pacemakers, Inc. Apparatus for treating the physiological electric conduction of the heart
US8812106B2 (en) 2004-12-20 2014-08-19 Cardiac Pacemakers, Inc. Apparatus for treating the physiological electric conduction of the heart
US8538521B2 (en) 2004-12-20 2013-09-17 Cardiac Pacemakers, Inc. Systems, devices and methods for monitoring efficiency of pacing
US8543203B2 (en) 2004-12-20 2013-09-24 Cardiac Pacemakers, Inc. Endocardial pacing devices and methods useful for resynchronization and defibrillation
US20080319499A1 (en) * 2004-12-20 2008-12-25 Qingsheng Zhu Devices and Methods for Steering Electrical Stimulation in Cardiac Rhythm Management
US8934969B2 (en) 2004-12-20 2015-01-13 Cardiac Pacemakers, Inc. Systems, devices and methods for monitoring efficiency of pacing
US20090187226A1 (en) * 2004-12-20 2009-07-23 Action Medical, Inc. Ventricular pacing
US10765867B2 (en) 2007-01-29 2020-09-08 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus and methods
US10561843B2 (en) 2007-01-29 2020-02-18 Lungpacer Medical, Inc. Transvascular nerve stimulation apparatus and methods
US10792499B2 (en) 2007-01-29 2020-10-06 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus and methods
US10864374B2 (en) 2007-01-29 2020-12-15 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus and methods
US11027130B2 (en) 2007-01-29 2021-06-08 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus and methods
US8688234B2 (en) 2008-12-19 2014-04-01 Cardiac Pacemakers, Inc. Devices, methods, and systems including cardiac pacing
US8694123B2 (en) * 2009-06-19 2014-04-08 Medtronic, Inc. Helical electrode arrangements for medical leads
US8929993B2 (en) 2009-06-19 2015-01-06 Medtronic, Inc. Electrode arrangements for suborbital foramen medical lead
US8509920B2 (en) 2009-06-19 2013-08-13 Medtronic, Inc. Electrode arrangements for medical lead
US20120078332A1 (en) * 2009-06-19 2012-03-29 Medtronic, Inc. Helical electrode arrangements for medical leads
WO2010148376A1 (en) * 2009-06-19 2010-12-23 Medtronic, Inc. Helical electrode arrangements for medical leads
US8565880B2 (en) 2010-04-27 2013-10-22 Cardiac Pacemakers, Inc. His-bundle capture verification and monitoring
US8639327B2 (en) 2010-04-29 2014-01-28 Medtronic, Inc. Nerve signal differentiation in cardiac therapy
US8406868B2 (en) 2010-04-29 2013-03-26 Medtronic, Inc. Therapy using perturbation and effect of physiological systems
US11129988B2 (en) 2010-04-29 2021-09-28 Medtronic, Inc. Nerve signal differentiation in cardiac therapy
US9468764B2 (en) 2010-04-29 2016-10-18 Medtronic, Inc. Nerve signal differentiation in cardiac therapy
US10207112B2 (en) 2010-04-29 2019-02-19 Medtronic, Inc. Cardiac therapy including vagal stimulation
US8888699B2 (en) 2010-04-29 2014-11-18 Medtronic, Inc. Therapy using perturbation and effect of physiological systems
US8620425B2 (en) 2010-04-29 2013-12-31 Medtronic, Inc. Nerve signal differentiation in cardiac therapy
US8423134B2 (en) 2010-04-29 2013-04-16 Medtronic, Inc. Therapy using perturbation and effect of physiological systems
US8706223B2 (en) 2011-01-19 2014-04-22 Medtronic, Inc. Preventative vagal stimulation
US8781583B2 (en) 2011-01-19 2014-07-15 Medtronic, Inc. Vagal stimulation
US9211413B2 (en) 2011-01-19 2015-12-15 Medtronic, Inc. Preventing use of vagal stimulation parameters
US8781582B2 (en) 2011-01-19 2014-07-15 Medtronic, Inc. Vagal stimulation
US8725259B2 (en) 2011-01-19 2014-05-13 Medtronic, Inc. Vagal stimulation
US9155893B2 (en) 2011-01-19 2015-10-13 Medtronic, Inc. Use of preventative vagal stimulation in treatment of acute myocardial infarction or ischemia
US8718763B2 (en) 2011-01-19 2014-05-06 Medtronic, Inc. Vagal stimulation
US11369787B2 (en) 2012-03-05 2022-06-28 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus and methods
US10512772B2 (en) 2012-03-05 2019-12-24 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus and methods
US10589097B2 (en) 2013-06-21 2020-03-17 Lungpacer Medical Inc. Transvascular diaphragm pacing systems and methods of use
US11357985B2 (en) 2013-06-21 2022-06-14 Lungpacer Medical Inc. Transvascular diaphragm pacing systems and methods of use
US10406367B2 (en) 2013-06-21 2019-09-10 Lungpacer Medical Inc. Transvascular diaphragm pacing system and methods of use
US10561844B2 (en) 2013-06-21 2020-02-18 Lungpacer Medical Inc. Diaphragm pacing systems and methods of use
US11707619B2 (en) 2013-11-22 2023-07-25 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
US9545511B2 (en) 2013-11-22 2017-01-17 Simon Fraser University Apparatus and methods for assisted breathing by transvascular nerve stimulation
US10035017B2 (en) 2013-11-22 2018-07-31 Lungpacer Medical, Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
US9931504B2 (en) 2013-11-22 2018-04-03 Lungpacer Medical, Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
US9242088B2 (en) 2013-11-22 2016-01-26 Simon Fraser University Apparatus and methods for assisted breathing by transvascular nerve stimulation
US10391314B2 (en) 2014-01-21 2019-08-27 Lungpacer Medical Inc. Systems and related methods for optimization of multi-electrode nerve pacing
US11311730B2 (en) 2014-01-21 2022-04-26 Lungpacer Medical Inc. Systems and related methods for optimization of multi-electrode nerve pacing
US9364659B1 (en) 2015-04-27 2016-06-14 Dantam K. Rao Smart lead for deep brain stimulation
US10293164B2 (en) 2017-05-26 2019-05-21 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
US12029901B2 (en) 2017-06-30 2024-07-09 Lungpacer Medical Inc. Devices and methods for prevention, moderation, and/or treatment of cognitive injury
US11883658B2 (en) 2017-06-30 2024-01-30 Lungpacer Medical Inc. Devices and methods for prevention, moderation, and/or treatment of cognitive injury
US11090489B2 (en) 2017-08-02 2021-08-17 Lungpacer Medical, Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10195429B1 (en) 2017-08-02 2019-02-05 Lungpacer Medical Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10926087B2 (en) 2017-08-02 2021-02-23 Lungpacer Medical Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US12029902B2 (en) 2017-08-02 2024-07-09 Lungpacer Medical Inc. Intravascular catheter methods
US10039920B1 (en) 2017-08-02 2018-08-07 Lungpacer Medical, Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10940308B2 (en) 2017-08-04 2021-03-09 Lungpacer Medical Inc. Systems and methods for trans-esophageal sympathetic ganglion recruitment
US11944810B2 (en) 2017-08-04 2024-04-02 Lungpacer Medical Inc. Systems and methods for trans-esophageal sympathetic ganglion recruitment
US12029903B2 (en) 2017-12-11 2024-07-09 Lungpacer Medical Inc. Systems and methods for strengthening a respiratory muscle
US11717673B2 (en) 2018-11-08 2023-08-08 Lungpacer Medical Inc. Stimulation systems and related user interfaces
US11890462B2 (en) 2018-11-08 2024-02-06 Lungpacer Medical Inc. Stimulation systems and related user interfaces
US10987511B2 (en) 2018-11-08 2021-04-27 Lungpacer Medical Inc. Stimulation systems and related user interfaces
US11357979B2 (en) 2019-05-16 2022-06-14 Lungpacer Medical Inc. Systems and methods for sensing and stimulation
US11771900B2 (en) 2019-06-12 2023-10-03 Lungpacer Medical Inc. Circuitry for medical stimulation systems

Also Published As

Publication number Publication date
JPS4920985A (en) 1974-02-23
FR2180907B1 (en) 1977-02-04
CA995763A (en) 1976-08-24
NL7305359A (en) 1973-10-19
DE2319499A1 (en) 1974-01-03
GB1423261A (en) 1976-02-04
AR200997A1 (en) 1975-02-06
FR2180907A1 (en) 1973-11-30

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