US3693625A - Heart stimulator and heart-powered energy supply therefor - Google Patents

Heart stimulator and heart-powered energy supply therefor Download PDF

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US3693625A
US3693625A US33745A US3693625DA US3693625A US 3693625 A US3693625 A US 3693625A US 33745 A US33745 A US 33745A US 3693625D A US3693625D A US 3693625DA US 3693625 A US3693625 A US 3693625A
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piston
heart
rotor
casing
movement
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Michel Joseph Auphan
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US Philips Corp
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372Arrangements in connection with the implantation of stimulators
    • A61N1/378Electrical supply
    • A61N1/3785Electrical supply generated by biological activity or substance, e.g. body movement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372Arrangements in connection with the implantation of stimulators
    • A61N1/378Electrical supply

Definitions

  • ABSTRACT A device for supplying electrical energy to a heart stimulator which is formed as an air-tight casing arranged to be placed within the human body in close proximity to the heart muscle.
  • the casing has housed therein an annularly arranged magnetic circuit with a rotor arranged in a gap of the circuit.
  • a rotary piston is accommodated within a piston chamber having four compartments divided in pairs. One of the pair is connected via a flexible tube to a first flexible bag arranged at the tip of the heart and the other pair communicates via another flexible hose to a second flexible elastic bag.
  • the elastic bags contain fluid which communicate alternately between the pairs of compartments within the chamber so that upon the pumping action of the heart the piston is caused to oscillate in a rotary motion and mechanical coupling means are connected between the piston and a driving member mounted coaxially with the rotor 50 as to drive the rotor thereby producing electrical signals in response to the movement of the heart.
  • This invention relates to a supply device for an intracorporal heart stimulator in the domain of medical prostheses.
  • Cardiac stimulators used for some diseases provide electric pulses to the myocardium by electrodes, different sources of energy are available for feeding these stimulators.
  • the apparatus forms not only an electric current generator but also a pulse generator for stimulating the heart. it comprises in an air-tight box a magnetic circuit, in the gap of which a rotor is adapted to oscillate between two pivots. An oscillation of the box produded by the movement of the heart causes the rotor to pass from an unstable position to a stable position and during this movement a sequence of rapid oscillations of the rotor induces in the magnetic circuit an oscillatory current of decreasing amplitude.
  • the box For transmitting the movement of the heart the box comprises a pendulum associated with a rotatable piece coaxial to said rotor and provided with a contact finger which co-operates with a pin of said rotor.
  • This system can only provide pulses at a predetermined frequency usually of about 1 Hz. For many cases it is, however, desirable to have available a system of variable frequency so that the heart may obtain pulses at different rhythms.
  • the present invention based on the same principle of mecano-electric transformation provides a supply device for an intracorporal heart stimulator, which may be of the conventional type.
  • the supply device is formed by a member converting mechanical energy into electric energy and comprises an oscillatory rotor arranged in the gap of a magnetic circuit and means for transmitting the movement of the heart to said rotor, which means comprise a rotatable piece coaxial to said rotor and provided with at least one mechanical contact member for driving said rotor.
  • said means further comprises a rotatable piston mechanically coupled with the rotatable piece and a member controlling the displacements of said piston in accordance with the movements of the heart.
  • FIG. 1 an elevation of the open casing comprising the supply device in accordance with the invention
  • FIG. 2 a schematic view of the rotatable piston shown at the center of FIG. 1;
  • FIG. 3 an over-all view of the casing and the transmission of the movements of the heart; and in FIG. 4 a schematic diagram showing the stimulator.
  • An airtight casing l accommodates an annular magnetic circuit 2a associated with a winding 2b, the gap accommodating a rotor 3.
  • Two auxiliary magnets 4 of the kind described in the aforesaid Patent Specification produce a magnetic field at right angles to the axis of the rotor and hence a return-couple for the latter.
  • the rotor is provided with a driving pin 5 co-operating with a finger 6 of a rotatable piece 7 which is coaxial to the rotor, the pin 5 and the finger 6 forming the mechanical contact elements for driving said rotor.
  • - rotatable piece is provided with a gear wheel 8 in mesh with the gear wheel 9 associated with a rotatable piston 11, mounted along the axis AA of the casing 1 inside the annular magnetic circuit.
  • the space 12 accommodating the piston 11 is divided into four chambers 13a, 13b, 14a and 14b of pairwise equal, variable volumes. These chambers (see FIGS. 2 and 3) are connected, as far as the first two are concerned by the flexible tube 15 with a plastic bag 18 arranged on the tip of the heart 17, the two others, by the flexible tube 16 with an elastic bag 19 of expansion.
  • the bag 18 is filled with a liquid.
  • the bag 18 is compressed between the tip of the heart and the surrounding tissues; the liquid is thus expelled into the flexible tube 15, it traverses the space 12 and emanates from the tube 16 towards the bag 19.
  • the tension of the second elastic bag pushes the liquid back to the first bag, which is no longer subjected to the pressure of the tip of the heart.
  • the rotatable piston l l is caused to perform an alternating movement which is transmitted by the gear wheels and produces the oscillation of the rotor under the action of the couple produced by the magnets 4.
  • the winding 2b of the magnetic circuit 2a is connected to the terminals of a first capacitor, so that an oscillatory circuit is formed. If the frequency of the latter lies near the oscillation frequency of the rotor, an automatic transmission of energy is obtained from the rotor to the oscillatory circuit.
  • the switch 24, the capacitor 25 and the stimulator 26 may be accommodated inside the casing 1 near the rotatable piston for instance. (not shown for the sake of clarity).
  • the pulses generated by the stimulator 26 are transmitted via leads 27 and 28 to electrodes schematically indicated by arrows 29 and 30, one of these electrodes may be formed by the casing l,-whereas the other (30, see FIG. 3) may be fixed to the flexible bag 18, when the liquid is conductive.
  • the driving system is formed by a magnetic coupling so that a shaft traversing the casing is not required.
  • the piston 11 is made of magnetic material and associated with two external, symmetrical magnets.
  • the invention may be used in the treatment of given cardial diseases by prostheses.
  • a device for supplying energy for an intracorporal heart stimulator comprising an airtight casing to be placed within the human body, an annularly arranged magnetic circuit housed within said casing, a winding coupled to said magnetic circuit to produce electrical energy said circuit having a gap therein, a rotor arranged in said gap for oscillatory movement, a multicompartment piston chamber arranged within said magnetic circuit, a piston mounted for rotatable movement within said chamber about an axis of rotation parallel and eccentric to the axis of rotation of said rotor, hydraulic means connected with said chamber for transmitting pulses thereto in response to movements of the heart so as to cause rotational displacement of said piston in accordance therewith, a driving member rotatably mounted coaxially with said rotor and having means contacting said rotor for driving same, and mechanical coupling means for causing movement of said driving member in response to rotational movement of said piston so that when said piston is rotatably driven as a result of heart movement said driving member will be caused to rotate and cause oscil
  • said piston chamber comprises first, second, third and fourth compartments, the volume of said first and third compartments being variable and equal to each other, the volume of said second and fourth compartments being variable and equal to each other and wherein said hydraulic means comprises a first flexible bag arranged on the tip of the heart, a first flexible liquid circulation tube connected to said first flexible bag and communicating with said first and third compartments, a second elastic bag of expansion and a second flexible liquid circulation tube connected to said second elastic bag of expansion and communicating with said second and fourth compartments.
  • the device according to claim 1 further comprising at least one magnet disposed near said rotor for roducin a ma etic field ndicular to said rotor.
  • said piston is mounted for rotation about an axis of the casing which is filled with air, and wherein said piston is made of magnetic material and further comprising a pair of magnets arranged symmetrically outside of said piston chamber so as to form a magnetic coupling thereby producing a drive for the piston.
  • the device according to claim 1 further comprising a capacitor connected to said winding and forming an oscillatory circuit for the transmission of the mechanical energy of the rotor.
  • said mechanical coupling means for causing movement of said driving member in response to rotational movement of said piston comprises a first gear wheel arranged on said driving member and a second gear wheel associated with said piston and arranged in mesh with said first gear wheel.
  • the device according to claim I further comprising a heart stimulator carried within said casing, an energy accumulator connected to said stimulator and a switch for connecting said oscillatory circuit to said energy accumulator, one of the electrodes of said stimulator being formed by said casing and the other electrode being fixed to said flexible bag at the tip of

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Magnetic Treatment Devices (AREA)
  • Electrotherapy Devices (AREA)
  • Permanent Magnet Type Synchronous Machine (AREA)

Abstract

A device for supplying electrical energy to a heart stimulator which is formed as an air-tight casing arranged to be placed within the human body in close proximity to the heart muscle. The casing has housed therein an annularly arranged magnetic circuit with a rotor arranged in a gap of the circuit. A rotary piston is accommodated within a piston chamber having four compartments divided in pairs. One of the pair is connected via a flexible tube to a first flexible bag arranged at the tip of the heart and the other pair communicates via another flexible hose to a second flexible elastic bag. The elastic bags contain fluid which communicate alternately between the pairs of compartments within the chamber so that upon the pumping action of the heart the piston is caused to oscillate in a rotary motion and mechanical coupling means are connected between the piston and a driving member mounted coaxially with the rotor so as to drive the rotor thereby producing electrical signals in response to the movement of the heart.

Description

United States Patent [15] 3,693,625 [451 Sept. 26, 1972 Auphan [54] HEART STIMULATOR AND HEART- POWERED ENERGY SUPPLY THEREFOR [72] Inventor: Michel Joseph Auphan, Courbevoie,
France [73] Assignee: U.S. Philips Corporation, New
York, N.Y.
[22] Filed: May 1, 1970 211 App]. No.: 33,745
[30] Foreign Application Priority Data May 13, 1969 France "6 915527 [52] U.S. Cl. ..l28/4l9 P, 128/419 B [51] Int. Cl. ..A61n H36 [58] Field ofSearch...128/1R, 419 P, 419 R; 310/37 [56] References Cited UNITED STATES PATENTS 3,486,506 12/1969 Auphan "128/419 P 3,563,245 2/1971 McLean ..l28/4l9 P 1,061,624 5/1913 Moere ..310/37 Primary Examiner-William E. Kamm Attorney-Frank R. Trifari [5 7] ABSTRACT A device for supplying electrical energy to a heart stimulator which is formed as an air-tight casing arranged to be placed within the human body in close proximity to the heart muscle. The casing has housed therein an annularly arranged magnetic circuit with a rotor arranged in a gap of the circuit. A rotary piston is accommodated within a piston chamber having four compartments divided in pairs. One of the pair is connected via a flexible tube to a first flexible bag arranged at the tip of the heart and the other pair communicates via another flexible hose to a second flexible elastic bag. The elastic bags contain fluid which communicate alternately between the pairs of compartments within the chamber so that upon the pumping action of the heart the piston is caused to oscillate in a rotary motion and mechanical coupling means are connected between the piston and a driving member mounted coaxially with the rotor 50 as to drive the rotor thereby producing electrical signals in response to the movement of the heart.
. 7 Claims, 4 Drawing Figures HEART STIMULATOR AND HEART-POWERED ENERGY SUPPLY THEREFOR This invention relates to a supply device for an intracorporal heart stimulator in the domain of medical prostheses.
Cardiac stimulators used for some diseases provide electric pulses to the myocardium by electrodes, different sources of energy are available for feeding these stimulators.
It is now common practice to use a battery within the body, but this involves two disadvantages: on the one hand the longevity of a battery is limited and on the other hand rupture of the flexible wires connecting the battery to the stimulator may occur due to shaking by the heart beat.
Research made on the sources of energy suitable for such uses tends to obviate these disadvantages by developing an autonomic source of energy, which will be substantially independent of time.
' In this respect research has been made for developing batteries having electrodes consumable by biological liquids. However, the longevity of these electrodes and any toxic effects they may have on the organism cannot be guaranteed.
Also, the use of thermal sources taking their energy from nuclear reaction involves many problems relating to either the dangers of the circulation of a radioactive material or the heat exchange at high temperatures also the cost of an apparatus based on this principle would be prohibitive I The use of the mechanical energy of the heart proposed in various methods should lead to an interesting solution. In fact, since the heart gives off about 15 W in contracting it must be capable of supplying the few hundred microwatts required for feeding a stimulator.
However, the mecano-electric transformation tests on piezo-electric materials have not produced the desired results. Since the charges accumulated at each mechanical deformation of the piezo-electric bodies are low, these deformations have to be accumulated to the highest possible frequency for obtaining a sufficient total energy.
A different solution has been described by the Applicant in French Pat. No. 1,460,772 and the Patent of Addition Nr. 92 782. The apparatus proposed forms not only an electric current generator but also a pulse generator for stimulating the heart. it comprises in an air-tight box a magnetic circuit, in the gap of which a rotor is adapted to oscillate between two pivots. An oscillation of the box produded by the movement of the heart causes the rotor to pass from an unstable position to a stable position and during this movement a sequence of rapid oscillations of the rotor induces in the magnetic circuit an oscillatory current of decreasing amplitude. For transmitting the movement of the heart the box comprises a pendulum associated with a rotatable piece coaxial to said rotor and provided with a contact finger which co-operates with a pin of said rotor. This system, however, can only provide pulses at a predetermined frequency usually of about 1 Hz. For many cases it is, however, desirable to have available a system of variable frequency so that the heart may obtain pulses at different rhythms.
The present invention based on the same principle of mecano-electric transformation provides a supply device for an intracorporal heart stimulator, which may be of the conventional type.
The supply device is formed by a member converting mechanical energy into electric energy and comprises an oscillatory rotor arranged in the gap of a magnetic circuit and means for transmitting the movement of the heart to said rotor, which means comprise a rotatable piece coaxial to said rotor and provided with at least one mechanical contact member for driving said rotor.
According to the invention said means further comprises a rotatable piston mechanically coupled with the rotatable piece and a member controlling the displacements of said piston in accordance with the movements of the heart.
Various characteristics of the invention will be apparent from the following description given by way of example with reference to the accompanying drawings, which show in FIG. 1 an elevation of the open casing comprising the supply device in accordance with the invention;
in FIG. 2 a schematic view of the rotatable piston shown at the center of FIG. 1;
in, FIG. 3 an over-all view of the casing and the transmission of the movements of the heart; and in FIG. 4 a schematic diagram showing the stimulator.
An airtight casing l accommodates an annular magnetic circuit 2a associated with a winding 2b, the gap accommodating a rotor 3. Two auxiliary magnets 4 of the kind described in the aforesaid Patent Specification produce a magnetic field at right angles to the axis of the rotor and hence a return-couple for the latter.
The rotor is provided with a driving pin 5 co-operating with a finger 6 of a rotatable piece 7 which is coaxial to the rotor, the pin 5 and the finger 6 forming the mechanical contact elements for driving said rotor. The
- rotatable piece is provided with a gear wheel 8 in mesh with the gear wheel 9 associated with a rotatable piston 11, mounted along the axis AA of the casing 1 inside the annular magnetic circuit. The space 12 accommodating the piston 11 is divided into four chambers 13a, 13b, 14a and 14b of pairwise equal, variable volumes. These chambers (see FIGS. 2 and 3) are connected, as far as the first two are concerned by the flexible tube 15 with a plastic bag 18 arranged on the tip of the heart 17, the two others, by the flexible tube 16 with an elastic bag 19 of expansion.
Initially the bag 18 is filled with a liquid. At each systole the bag 18 is compressed between the tip of the heart and the surrounding tissues; the liquid is thus expelled into the flexible tube 15, it traverses the space 12 and emanates from the tube 16 towards the bag 19. After the systole the tension of the second elastic bag pushes the liquid back to the first bag, which is no longer subjected to the pressure of the tip of the heart.
During each reciprocatory flow of the liquid, the rotatable piston l l is caused to perform an alternating movement which is transmitted by the gear wheels and produces the oscillation of the rotor under the action of the couple produced by the magnets 4.
The winding 2b of the magnetic circuit 2a is connected to the terminals of a first capacitor, so that an oscillatory circuit is formed. If the frequency of the latter lies near the oscillation frequency of the rotor, an automatic transmission of energy is obtained from the rotor to the oscillatory circuit.
Each time when the energy reaches its maximum level, it is transmitted, for example, by an electric switch 24, to a second capacitor 25 for feeding a stimulator 26 of conventional type.
The switch 24, the capacitor 25 and the stimulator 26 may be accommodated inside the casing 1 near the rotatable piston for instance. (not shown for the sake of clarity).
The pulses generated by the stimulator 26 are transmitted via leads 27 and 28 to electrodes schematically indicated by arrows 29 and 30, one of these electrodes may be formed by the casing l,-whereas the other (30, see FIG. 3) may be fixed to the flexible bag 18, when the liquid is conductive. a
In order to ensure a perfect seal between the space 12 and the assemblyof the device the driving system is formed by a magnetic coupling so that a shaft traversing the casing is not required.
For this purpose the piston 11 is made of magnetic material and associated with two external, symmetrical magnets.
The invention may be used in the treatment of given cardial diseases by prostheses.
What is claimed is:
l. A device for supplying energy for an intracorporal heart stimulator, comprising an airtight casing to be placed within the human body, an annularly arranged magnetic circuit housed within said casing, a winding coupled to said magnetic circuit to produce electrical energy said circuit having a gap therein, a rotor arranged in said gap for oscillatory movement, a multicompartment piston chamber arranged within said magnetic circuit, a piston mounted for rotatable movement within said chamber about an axis of rotation parallel and eccentric to the axis of rotation of said rotor, hydraulic means connected with said chamber for transmitting pulses thereto in response to movements of the heart so as to cause rotational displacement of said piston in accordance therewith, a driving member rotatably mounted coaxially with said rotor and having means contacting said rotor for driving same, and mechanical coupling means for causing movement of said driving member in response to rotational movement of said piston so that when said piston is rotatably driven as a result of heart movement said driving member will be caused to rotate and cause oscillatory movement of said rotor so as to produce electrical energy. I
2. The device according to claim 1 wherein said piston chamber comprises first, second, third and fourth compartments, the volume of said first and third compartments being variable and equal to each other, the volume of said second and fourth compartments being variable and equal to each other and wherein said hydraulic means comprises a first flexible bag arranged on the tip of the heart, a first flexible liquid circulation tube connected to said first flexible bag and communicating with said first and third compartments, a second elastic bag of expansion and a second flexible liquid circulation tube connected to said second elastic bag of expansion and communicating with said second and fourth compartments.
3. The device according to claim 1 further comprising at least one magnet disposed near said rotor for roducin a ma etic field ndicular to said rotor. p 4. The devic e according claim 1 wherein said piston is mounted for rotation about an axis of the casing which is filled with air, and wherein said piston is made of magnetic material and further comprising a pair of magnets arranged symmetrically outside of said piston chamber so as to form a magnetic coupling thereby producing a drive for the piston.
5. The device according to claim 1 further comprising a capacitor connected to said winding and forming an oscillatory circuit for the transmission of the mechanical energy of the rotor.
6. The device according to claim 1 wherein said mechanical coupling means for causing movement of said driving member in response to rotational movement of said piston comprises a first gear wheel arranged on said driving member and a second gear wheel associated with said piston and arranged in mesh with said first gear wheel.
7. The device according to claim I further comprising a heart stimulator carried within said casing, an energy accumulator connected to said stimulator and a switch for connecting said oscillatory circuit to said energy accumulator, one of the electrodes of said stimulator being formed by said casing and the other electrode being fixed to said flexible bag at the tip of

Claims (7)

1. A device for supplying energy for an intracorporal heart stimulator, comprising an airtight casing to be placed within the human body, an annularly arranged magnetic circuit housed within said casing, a winding coupled to said magnetic circuit to produce electrical energy said circuit having a gap therein, a rotor arranged in said gap for oscillatory movement, a multicompartment piston chamber arranged within said magnetic circuit, a piston mounted for rotatable movement within said chamber about an axis of rotation parallel and eccentric to the axis of rotation of said rotor, hydraulic means connected with said chamber for transmitting pulses thereto in response to movements of the heart so as to cause rotational displacement of said piston in accordance therewith, , a driving member rotatably mounted coaxially with said rotor and having means contacting said rotor for driving same, and mechanical coupling means for causing movement of said driving member in response to rotational movement of said piston so that when said piston is rotatably driven as a result of heart movement said driving member will be caused to rotate and cause oscillatory movement of said rotor so as to produce electrical energy.
2. The device according to claim 1 wherein said piston chamber comprises first, second, third and fourth compartments, the volume of said first and third compartments being variable and equal to each other, the volume of said second and fourth compartments being variable and equal to each other and wherein said hydraulic means comprises a first flexible bag arranged on the tip of the heart, a first flexible liquid circulation tube connected to said first flexible bag and communicating with said first and third compartments, a second elastic bag of expansion and a second flexible liquid circulation tube connected to said second elastic bag of expansion and communicating with said second and fourth compartments.
3. The device according to claim 1 further comprising at least one magnet disposed near said rotor for producing a magnetic field perpendicular to said rotor.
4. The device according to claim 1 wherein said piston is mounted for rotation about an axis of the casing which is filled with air, and wherein said piston is made of magnetic material and further comprising a pair of magnets arranged symmetrically outside of said piston chamber so as to form a magnetic coupling thereby producing a drive for the piston.
5. The device according to claim 1 further comprising a capacitor connected to said winding and forming an oscillatory circuit for the transmission of the mechanical energy of the rotor.
6. The device according to claim 1 wherein said mechanical coupling means for causing movement of said driving member in response to rotational movement of said piston comprises a first gear wheel arranged on said driving member and a second gear wheel associated with said piston and arranged in mesh with said first gear wheel.
7. The device according to claim 1 further comprising a heart stimulator carried within said casing, an energy accumulator connected to said stimulator and a switch for connecting said oscillatory circuit to said energy accumulator, one of the electrodes of said stimulator being formed by said casing and the other electrode being fixed to said flexible bag at the tip of the heart.
US33745A 1969-05-13 1970-05-01 Heart stimulator and heart-powered energy supply therefor Expired - Lifetime US3693625A (en)

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SE (1) SE360980B (en)

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US4510935A (en) * 1981-10-28 1985-04-16 Cardiac Recorders Limited Cardiac defibrillator
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US20050288726A1 (en) * 2001-10-01 2005-12-29 Scicotec Gmbh Method and device for using impedance measurements based on electrical energy of the heart
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US20070276444A1 (en) * 2006-05-24 2007-11-29 Daniel Gelbart Self-powered leadless pacemaker
US20070293904A1 (en) * 2006-06-20 2007-12-20 Daniel Gelbart Self-powered resonant leadless pacemaker
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US20110087304A1 (en) * 2001-10-01 2011-04-14 Maik Gollasch Method of vagal stimulation to treat patients suffering from congestive heart failure
US9084859B2 (en) 2011-03-14 2015-07-21 Sleepnea Llc Energy-harvesting respiratory method and device
US9289612B1 (en) 2014-12-11 2016-03-22 Medtronic Inc. Coordination of ventricular pacing in a leadless pacing system
US9399140B2 (en) 2014-07-25 2016-07-26 Medtronic, Inc. Atrial contraction detection by a ventricular leadless pacing device for atrio-synchronous ventricular pacing
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US9492669B2 (en) 2014-11-11 2016-11-15 Medtronic, Inc. Mode switching by a ventricular leadless pacing device
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US9597521B2 (en) 2015-01-21 2017-03-21 Bluewind Medical Ltd. Transmitting coils for neurostimulation
US9623234B2 (en) 2014-11-11 2017-04-18 Medtronic, Inc. Leadless pacing device implantation
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US9782589B2 (en) 2015-06-10 2017-10-10 Bluewind Medical Ltd. Implantable electrostimulator for improving blood flow
US9861812B2 (en) 2012-12-06 2018-01-09 Blue Wind Medical Ltd. Delivery of implantable neurostimulators
US10004896B2 (en) 2015-01-21 2018-06-26 Bluewind Medical Ltd. Anchors and implant devices
US10105540B2 (en) 2015-11-09 2018-10-23 Bluewind Medical Ltd. Optimization of application of current
US10124178B2 (en) 2016-11-23 2018-11-13 Bluewind Medical Ltd. Implant and delivery tool therefor
US10390720B2 (en) 2014-07-17 2019-08-27 Medtronic, Inc. Leadless pacing system including sensing extension
US10653888B2 (en) 2012-01-26 2020-05-19 Bluewind Medical Ltd Wireless neurostimulators
US11207527B2 (en) 2016-07-06 2021-12-28 Cardiac Pacemakers, Inc. Method and system for determining an atrial contraction timing fiducial in a leadless cardiac pacemaker system
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DE2020380A1 (en) 1970-11-19
JPS502551B1 (en) 1975-01-27
DE2020380C2 (en) 1982-09-02
SE360980B (en) 1973-10-15
GB1281646A (en) 1972-07-12
FR2044246A5 (en) 1971-02-19

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