US3137242A - Infusion pump - Google Patents

Infusion pump Download PDF

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US3137242A
US3137242A US167820A US16782062A US3137242A US 3137242 A US3137242 A US 3137242A US 167820 A US167820 A US 167820A US 16782062 A US16782062 A US 16782062A US 3137242 A US3137242 A US 3137242A
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arms
tube
housing
groove
recess
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US167820A
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Hahn George William
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    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00Machines, pumps, or pumping installations having flexible working members
    • F04B43/12Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1253Machines, pumps, or pumping installations having flexible working members having peristaltic action by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing
    • F04B43/1276Means for pushing the rollers against the tubular flexible member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps

Definitions

  • a prime object of the invention resides in the provision of a pump by which a medicament, such as methotrexate, can be injected Iinto the arteries, in the treatment of malignant diseases, from a reservoir at predetermined rates and pressures without contamination.
  • a medicament such as methotrexate
  • An important object of the invention is that of providing a pump of the character described in which fluids, such as medicaments, can be injected into the arterial system from a reservoir in carefully measured quantities at constant pressures, and regulated in accordance with blood pressures encountered.
  • a further object of the invention resides in the provision of an infusion pump having a variable speed, which is highly desirable in the treatment of malignancies, such as cancer, due to the necessity for extreme accuracy in the injection of carefully measured quantities of medicaments during prolonged periods of time.
  • the invention contemplates the provision of a iluid pump by which various types of liquids can be moved in accurately measured quantities, at various constant speeds, depending upon the pressures required, and Without subjecting the liquid products to contamination, utilizing a flexible conduit which can be maintained under accurately predetermined and constant pressure.
  • FIGURE 1 is a front elevational View of a pump em bodying the invention, showing the tensioned roller arms operating in an annular recess.
  • FIGURE 2 is a transverse sectional view, on line 2--2 of FIGURE l, through the gear housing and the annular roller recess, illustrating the variable speed motor, the rheostat control and the gear assembly.
  • FIGURE 3 is a side elevational view of the invention, showing the motor and control knobs.
  • FIGURE 4 is an enlarged fragmentary illustration of one yof the roller arms, and roller impinging the flexible tube, the latter and the housing being shown partially in section.
  • FIGURE 5 is a fragmentary sectional view, on line 5 5 of FIGURE 4, showing a roller compressing the tube in the groove formed peripherally of the annular recess in the housing, and
  • FIGURE 6 fragmentarily illustrates a modified arrangement of tensioning springs for the roller arms.
  • apparatus embodying the invention is mounted on a base member 10 having a relatively thin housing 11 supported vertically along one side, as shown in FIGURES l', 2 and 3.
  • a panel 12 is ⁇ arranged along an edge of the base 10 at right angles to the housing 11, and these elements are preferably formed of a plastic material.
  • a circular opening 14 Formed in the face plate 13 on the housing 11 is a circular opening 14 about the inner surface of which is defined a channel 15 adapted to receive a ilexible cornpressible tube 16 of plastic, or other suitable material, as shown best in FIGURES l and 4.
  • a pair of grooves 17 are formed in the face plate 13 of the housing 11 which communicate with the channel 15 and extend vertically into the top of the face plate 13, as illustrated in FIGURE l, and receive the inlet and outlet portions 18 and 19 of the tube 16 which are retained in the grooves 17 by pins 20, or other suitable devices.
  • a disk 21 is mounted for rotation concentrically of the circular recess or opening 14 on a shaft 22 which is sup ported in bearings 23 and 24 pressed into annular recesses 25 and 26, respectively, in the front and rear walls 27 and 28 of the housing 11, as shown in FIGURE 2.
  • a plurality of arms 29 are pivoted at a intermediate their ends about the disk 21 near its perimeter, and are equidistantly spaced, and each arm 29 has a roller 30 pivoted to its outer end adapted to engage and compress the tube 16 under the tension of an endless pull spring 31, in the manner shown in FIGURE l.
  • each of the arms 29, opposite the roller 30 thereon has a pulley 32 pivotally attached there to and rotates on a screw 33, and the spring 31, which is in the form of a belt, is passed over each of the pulleys 32 and exerts an equal tension on the arms 29, whose fulcrums a are intermediate their ends, whereby the rollers 30 are caused to bear against the tube 16 with equal predetermined pressure.
  • the disk 21 is rotated clockwise, as indicated by the arrow, so that uid from a reservoir (not shown) entering that portion of the tube 16 through the inlet portion 18, is moved around that portion of the tube 16 lying in the circular channel 15 by the pressure of the rollers 30 thereon, and out through the outlet portion 19 of the tube 16 in a constant, non-pulsating flow.
  • a relatively large gear 35 arranged in the shaft 22, and is secured to the latter by an integral collar 36 through the medium of a set screw 37, as shown in FIG- URE 2.
  • the gear 35 is meshed with a smaller gear 38 on the shaft 39 of a motor 40 mounted by screws 41 on the back of the rear wall 28 of the housing 11.
  • the motor 40 is of the variable speed type and is controlled by a rheostat 42 on the panel 12 through the knob 43.
  • a manual switch 44 is connected into the motor circuit and is also mounted .on the panel 12, as well as a fuse 46 and a jack plug receptacle 46 by which the motor circuit is connected through a transformer (not shown) to a service outlet.
  • the motor 40 be capable of variable speeds, and accurately controlled, in order that it mayI be readily adjusted to ioperate the pump at the proper speed to suit the type and rate of medication required to be injected or infused into the arterial system of a patient. It is also important that the speed of the motor 40 be constant when the rheostat 42 is properly adjusted.
  • FIGURE 6 is a fragmentarily illustrated in a moditied arrangement of the spring tensioning means for the arms 29 by which the rollers 30 are held in engagement with the tube 16.
  • a plurality of individual springs 47 are provided whose ends are secured to the screws 33 on the inner ends of the arms 29. T his arrangement, while capable of maintaining a constant pressure on the tube 16 when each spring 47 has a uniform pull, the endless spring 31 is more dependable for uniformity and flexibility, particularly since the rollers 32 will provide for equalization of tension between the arms 29 and pressure on the tube 16 will not be relaxed at any point due to weakening of a spring 4'7 by fatigue or other cause.
  • the assembly is adapted to be supported on a table surface by legs 48 attached to the base 1t), or may be suspended on a rack or other supporting means, and cornpletely enclosed in a cabinet of any suitable design.
  • an infusion pump for medicaments having a base plate and a pair of vertical parallel walls along one side defining a housing, and a vertical panel arranged along an end of said base at right angles to said housing, the combination comprising, a face panel on the outer wall of said housing having a circular recess therein and a groove formed peripherally of said recess, a flexible tube arranged in said groove and having fluid inlet and outlet ends, a circular disk rotatively mounted concentrically of said recess, a plurality of arms pivotally attached intermediate their ends to said disk about the periphery thereof, and a roller pivoted to the outer end of each of said arms engageable with said tube in said groove to compress said tube progressively about said groove, a pulley pivoted on the inner end of each of said arms, an endless pull spring collectively embracing said pulleys connecting the inner ends of said arms for exerting tension thereon, and a vari- 4. able speed motor for rotating said disk and said arms thereon.
  • an infusion pump of medicaments having a base, a housing having a circular recess in its outer wall, a peripheral groove in said recess, and a variable speed "motor for driving said pump, the structure comprising, a disk rotatably mounted concentrically of said recess, a flexible flow tube adapted to lie in said peripheral groove in said recess, a plurality of arms spaced about the said disk and pivoted thereto intermediate their ends whereby their longitudinal axes are tangential to the axis of said disk, a roller attached to the outer end of each of said arms and engaging said flexible tube to compress the same progressively about said groove, a pulley pivotally arranged on the inner end of each of said arms, and an endless pull spring arranged about said pulleys whereby to exert pressure on said tube.
  • An infusion pump for injecting medicaments into the arterial system a base element, and a housing thereon having a circular recess in a wall thereof, and a groove formed peripherally of said recess, and a compressible tube arranged in the groove in said recess having connection with a fluid source
  • the improvements comprising, a Sdisk rotatable concentrically of said recess and having means for rotating the same, a plurality of arms pivoted intermediate their ends about the outer edge of said disk, each having a roller pivoted to its outer end and engageable with said tube, a pulley on the inner end of each of said arms opposite said rollers, and a pull spring arranged about said pulleys operatively connecting the inner ends of said arms and exerting collective tension thereon whereby said rollers progressively compress said tube along said groove.

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Description

June 16, 1964 G. w. HAHN 3,137,242
INFUSION PUMP Filed Jan. 22, 1962 2 Sheets-Sheet 1 4g I d@ fz /4 55 Zi Z9 .30 INVENTOR FigI 2 Z2 ya; l George WHahn G. w. HAHN 3,137,242
INFUSION PUMP 2 Sheets-Sheet 2 m, f M f a e June 16, 1964 Filed Jan. 22, 1962 1 l... ...MEF-3G52 United States Patent O 3,137,242 INFUSIN PUMP George William Hahn, 1605 Pentagon Parkway, Dallas, Tex. Filed Jan. 22, 1962, Ser. No. 167,820 3 Claims. (Cl. 103-152) This invention relates to lluid pumps of the type generally referred to as infusion pumps, and it has particular reference to surgical pumps utilized to inject fluid intravenously in the treatment of diseases, such as cancer, malnutrition, and the like, and the infusion of blood plasma, and other uids into the blood istream.
A prime object of the invention resides in the provision of a pump by which a medicament, such as methotrexate, can be injected Iinto the arteries, in the treatment of malignant diseases, from a reservoir at predetermined rates and pressures without contamination.
Pumps of the type described have been in general use for several years, and include such elements as radially arranged tensioned rollers in an annular chamber and engaging a exible tube to induce a iluid flow for a variety of purposes. However, such known devices are lacking in many of the features which will become apparent in the improvements hereinafter described, particularly in respect to the extreme accuracy and precision necessary in the application of such improvements in the treatment of diseases. i
An important object of the invention is that of providing a pump of the character described in which fluids, such as medicaments, can be injected into the arterial system from a reservoir in carefully measured quantities at constant pressures, and regulated in accordance with blood pressures encountered.
A further object of the invention resides in the provision of an infusion pump having a variable speed, which is highly desirable in the treatment of malignancies, such as cancer, due to the necessity for extreme accuracy in the injection of carefully measured quantities of medicaments during prolonged periods of time.
It is also an object of the invention to provide an infusion pump which is simple in design and structure, and thoroughly dependable in operation, and by which any type of liquids can be transmitted thereby in a constant, uninterrupted ow, without the intermittent surging and pulsations attributable to many conventional pumps designed for similar purposes.
Broadly, the invention contemplates the provision of a iluid pump by which various types of liquids can be moved in accurately measured quantities, at various constant speeds, depending upon the pressures required, and Without subjecting the liquid products to contamination, utilizing a flexible conduit which can be maintained under accurately predetermined and constant pressure.
While the foregoing objects are paramount, other and lesser objects will become manifest as the description proceeds, taken in connection with the appended drawings wherein:
FIGURE 1 is a front elevational View of a pump em bodying the invention, showing the tensioned roller arms operating in an annular recess.
FIGURE 2 is a transverse sectional view, on line 2--2 of FIGURE l, through the gear housing and the annular roller recess, illustrating the variable speed motor, the rheostat control and the gear assembly.
FIGURE 3 is a side elevational view of the invention, showing the motor and control knobs.
FIGURE 4 is an enlarged fragmentary illustration of one yof the roller arms, and roller impinging the flexible tube, the latter and the housing being shown partially in section.
3,137,242 Patented June 16, 1964 ICC FIGURE 5 is a fragmentary sectional view, on line 5 5 of FIGURE 4, showing a roller compressing the tube in the groove formed peripherally of the annular recess in the housing, and
FIGURE 6 fragmentarily illustrates a modified arrangement of tensioning springs for the roller arms.
Accordingly, referring to the drawings, apparatus embodying the invention is mounted on a base member 10 having a relatively thin housing 11 supported vertically along one side, as shown in FIGURES l', 2 and 3. A panel 12 is `arranged along an edge of the base 10 at right angles to the housing 11, and these elements are preferably formed of a plastic material.
Formed in the face plate 13 on the housing 11 is a circular opening 14 about the inner surface of which is defined a channel 15 adapted to receive a ilexible cornpressible tube 16 of plastic, or other suitable material, as shown best in FIGURES l and 4. A pair of grooves 17 are formed in the face plate 13 of the housing 11 which communicate with the channel 15 and extend vertically into the top of the face plate 13, as illustrated in FIGURE l, and receive the inlet and outlet portions 18 and 19 of the tube 16 which are retained in the grooves 17 by pins 20, or other suitable devices.
A disk 21 is mounted for rotation concentrically of the circular recess or opening 14 on a shaft 22 which is sup ported in bearings 23 and 24 pressed into annular recesses 25 and 26, respectively, in the front and rear walls 27 and 28 of the housing 11, as shown in FIGURE 2. A plurality of arms 29 are pivoted at a intermediate their ends about the disk 21 near its perimeter, and are equidistantly spaced, and each arm 29 has a roller 30 pivoted to its outer end adapted to engage and compress the tube 16 under the tension of an endless pull spring 31, in the manner shown in FIGURE l.
The inner end of each of the arms 29, opposite the roller 30 thereon, has a pulley 32 pivotally attached there to and rotates on a screw 33, and the spring 31, which is in the form of a belt, is passed over each of the pulleys 32 and exerts an equal tension on the arms 29, whose fulcrums a are intermediate their ends, whereby the rollers 30 are caused to bear against the tube 16 with equal predetermined pressure. The disk 21 is rotated clockwise, as indicated by the arrow, so that uid from a reservoir (not shown) entering that portion of the tube 16 through the inlet portion 18, is moved around that portion of the tube 16 lying in the circular channel 15 by the pressure of the rollers 30 thereon, and out through the outlet portion 19 of the tube 16 in a constant, non-pulsating flow.
In the space 34 defined between the front and rear walls 27 and 28 is a relatively large gear 35 arranged in the shaft 22, and is secured to the latter by an integral collar 36 through the medium of a set screw 37, as shown in FIG- URE 2. The gear 35 is meshed with a smaller gear 38 on the shaft 39 of a motor 40 mounted by screws 41 on the back of the rear wall 28 of the housing 11.
The motor 40 is of the variable speed type and is controlled by a rheostat 42 on the panel 12 through the knob 43. A manual switch 44 is connected into the motor circuit and is also mounted .on the panel 12, as well as a fuse 46 and a jack plug receptacle 46 by which the motor circuit is connected through a transformer (not shown) to a service outlet.
It is very important that the motor 40 be capable of variable speeds, and accurately controlled, in order that it mayI be readily adjusted to ioperate the pump at the proper speed to suit the type and rate of medication required to be injected or infused into the arterial system of a patient. It is also important that the speed of the motor 40 be constant when the rheostat 42 is properly adjusted.
ademas In FIGURE 6 is a fragmentarily illustrated in a moditied arrangement of the spring tensioning means for the arms 29 by which the rollers 30 are held in engagement with the tube 16. In this structure a plurality of individual springs 47 are provided whose ends are secured to the screws 33 on the inner ends of the arms 29. T his arrangement, while capable of maintaining a constant pressure on the tube 16 when each spring 47 has a uniform pull, the endless spring 31 is more dependable for uniformity and flexibility, particularly since the rollers 32 will provide for equalization of tension between the arms 29 and pressure on the tube 16 will not be relaxed at any point due to weakening of a spring 4'7 by fatigue or other cause.
The assembly is adapted to be supported on a table surface by legs 48 attached to the base 1t), or may be suspended on a rack or other supporting means, and cornpletely enclosed in a cabinet of any suitable design.
The invention, while described with great particularity, is capable of certain changes and modifications from time to time, by persons skilled in the art, without departing from the spirit and intent thereof or the scope of the appended claims.
What is claimed is:
1. In an infusion pump for medicaments having a base plate and a pair of vertical parallel walls along one side defining a housing, and a vertical panel arranged along an end of said base at right angles to said housing, the combination comprising, a face panel on the outer wall of said housing having a circular recess therein and a groove formed peripherally of said recess, a flexible tube arranged in said groove and having fluid inlet and outlet ends, a circular disk rotatively mounted concentrically of said recess, a plurality of arms pivotally attached intermediate their ends to said disk about the periphery thereof, and a roller pivoted to the outer end of each of said arms engageable with said tube in said groove to compress said tube progressively about said groove, a pulley pivoted on the inner end of each of said arms, an endless pull spring collectively embracing said pulleys connecting the inner ends of said arms for exerting tension thereon, and a vari- 4. able speed motor for rotating said disk and said arms thereon.
2. In an infusion pump of medicaments, having a base, a housing having a circular recess in its outer wall, a peripheral groove in said recess, and a variable speed "motor for driving said pump, the structure comprising, a disk rotatably mounted concentrically of said recess, a flexible flow tube adapted to lie in said peripheral groove in said recess, a plurality of arms spaced about the said disk and pivoted thereto intermediate their ends whereby their longitudinal axes are tangential to the axis of said disk, a roller attached to the outer end of each of said arms and engaging said flexible tube to compress the same progressively about said groove, a pulley pivotally arranged on the inner end of each of said arms, and an endless pull spring arranged about said pulleys whereby to exert pressure on said tube.
3. An infusion pump for injecting medicaments into the arterial system, a base element, and a housing thereon having a circular recess in a wall thereof, and a groove formed peripherally of said recess, and a compressible tube arranged in the groove in said recess having connection with a fluid source, the improvements comprising, a Sdisk rotatable concentrically of said recess and having means for rotating the same, a plurality of arms pivoted intermediate their ends about the outer edge of said disk, each having a roller pivoted to its outer end and engageable with said tube, a pulley on the inner end of each of said arms opposite said rollers, and a pull spring arranged about said pulleys operatively connecting the inner ends of said arms and exerting collective tension thereon whereby said rollers progressively compress said tube along said groove.
References Cited in the ile of this patent UNITED STATES PATENTS 87,837 Gilmore Mar. 16, 1869 1,988,337 Santiago et al Jan. l5, 1935 2,314,281 Knott Mar. 16, 1943 `2,695,117 Daniels Nov. 23, 1954

Claims (1)

1. IN AN INFUSION PUMP FOR MEDICAMENTS HAVING A BASE PLATE AND A PAIR OF VERTICAL PARALLEL WALLS ALONG ONE SIDE DEFINING A HOUSING, AND A VERTICAL PANEL ARRANGED ALONG AN END OF SAID BASE AT RIGHT ANGLES TO SAID HOUSING, THE COMBINATION COMPRISING, A FACE PANEL ON THE OUTER WALL OF SAID HOUSING HAVING A CIRCULAR RECESS THEREIN AND A GROOVE FORMED PERIPHERALLY OF SAID RECESS, A FLEXIBLE TUBE ARRANGED IN SAID GROOVE AND HAVING FLUID INLET AND OUTLET ENDS, A CIRCULAR DISK ROTATIVELY MOUNTED CONCENTRICALLY OF SAID RECESS, A PLURALITY OF ARMS PIVOTALLY ATTACHED INTERMEDIATE THEIR ENDS TO SAID DISK ABOUT THE PERIPHERY THEREOF, AND A ROLLER PIVOTED TO THE OUTER END OF EACH OF SAID ARMS ENGAGEABLE WITH SAID TUBE IN SAID GROOVE TO COMPRESS SAID TUBE PROGRESSIVELY ABOUT SAID GROOVE, A PULLEY PIVOTED ON THE INNER END OF EACH OF SAID ARMS, AN ENDLESS PULL SPRING COLLECTIVELY EMBRACING SAID PULLEYS CONNECTING THE INNER ENDS OF SAID ARMS FOR EXERTING TENSION THEREON, AND A VARIABLE SPEED MOTOR FOR ROTATING SAID DISK AND SAID ARMS THEREON.
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Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3384080A (en) * 1964-10-16 1968-05-21 Us Catheter & Instr Corp Portable spring powered infusion device having escapement means controlling speed ofinfusion
US3415419A (en) * 1966-10-27 1968-12-10 Jewett Fluid administering system
US3425415A (en) * 1966-05-02 1969-02-04 Iit Res Inst Controlled infusion system
US3496878A (en) * 1967-04-07 1970-02-24 Bio Medical Systems Inc System and apparatus for transfer of human fluids
US4229299A (en) * 1978-03-22 1980-10-21 Hoechst Aktiengesellschaft Peristaltic dialysate solution pump
US4231707A (en) * 1978-01-31 1980-11-04 Pilot Man-Nen-Hitsu Kabushiki Kaisha Fluid supplying device
US4365728A (en) * 1978-03-13 1982-12-28 Pilot Man-Nen-Hitsu Kabushiki Kaisha Liquid discharge apparatus
NL8303495A (en) * 1983-10-12 1985-05-01 Unilever Nv PERISTALTIC PUMP.
US4586882A (en) * 1984-12-06 1986-05-06 Baxter Travenol Laboratories, Inc. Tubing occluder pump
US4705464A (en) * 1986-05-09 1987-11-10 Surgidev Corporation Medicine pump
US4725205A (en) * 1987-01-30 1988-02-16 Fisher Scientific Group Inc. Peristaltic pump with cam action compensator
US4728265A (en) * 1987-01-30 1988-03-01 Fisher Scientific Group Inc. Peristaltic pump with cam action compensator
US4856972A (en) * 1988-06-09 1989-08-15 Fisher Scientific Co. Dual roller peristaltic pump
US4950136A (en) * 1989-08-14 1990-08-21 Hydro Systems Company Peristaltic pump
US5470211A (en) * 1993-08-12 1995-11-28 Stockert Instrumente Gmbh Roller pump
WO1999042726A1 (en) * 1998-02-19 1999-08-26 The University Of Melbourne Linearised peristaltic pump
US6736617B2 (en) 2002-02-20 2004-05-18 Terumo Cardiovascular Systems Corporation Peristaltic pump having automatically adjusting bushing
US20140044579A1 (en) * 2012-08-08 2014-02-13 Kuwait University Rotary diaphragm pump
US8663538B2 (en) 2009-02-12 2014-03-04 Picolife Technologies, Llc Method of making a membrane for use with a flow control system for a micropump
US8771229B2 (en) 2011-12-01 2014-07-08 Picolife Technologies, Llc Cartridge system for delivery of medicament
US8790307B2 (en) 2011-12-01 2014-07-29 Picolife Technologies, Llc Drug delivery device and methods therefor
US20140356202A1 (en) * 2013-05-30 2014-12-04 Alcon Research, Ltd. Pump roller head with pivoting rollers and spring arms
US9797390B2 (en) 2013-05-30 2017-10-24 Novartis Ag Pump roller assembly with flexible arms
US9797391B2 (en) 2013-05-30 2017-10-24 Novartis Ag Pump roller assembly with independently sprung pivoting rollers
US9883834B2 (en) 2012-04-16 2018-02-06 Farid Amirouche Medication delivery device with multi-reservoir cartridge system and related methods of use
US10041488B2 (en) 2013-05-30 2018-08-07 Novartis Ag Pump roller assembly with independently sprung rollers
US10130759B2 (en) 2012-03-09 2018-11-20 Picolife Technologies, Llc Multi-ported drug delivery device having multi-reservoir cartridge system
US10245420B2 (en) 2012-06-26 2019-04-02 PicoLife Technologies Medicament distribution systems and related methods of use

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US87837A (en) * 1869-03-16 Othniel gilmore
US1988337A (en) * 1933-12-21 1935-01-15 Santiago Manoel Cordeiro Pump
US2314281A (en) * 1941-03-28 1943-03-16 Emmet K Knott Pumping apparatus
US2695117A (en) * 1952-01-24 1954-11-23 Paul J Daniels Beverage dispensing apparatus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US87837A (en) * 1869-03-16 Othniel gilmore
US1988337A (en) * 1933-12-21 1935-01-15 Santiago Manoel Cordeiro Pump
US2314281A (en) * 1941-03-28 1943-03-16 Emmet K Knott Pumping apparatus
US2695117A (en) * 1952-01-24 1954-11-23 Paul J Daniels Beverage dispensing apparatus

Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3384080A (en) * 1964-10-16 1968-05-21 Us Catheter & Instr Corp Portable spring powered infusion device having escapement means controlling speed ofinfusion
US3425415A (en) * 1966-05-02 1969-02-04 Iit Res Inst Controlled infusion system
US3415419A (en) * 1966-10-27 1968-12-10 Jewett Fluid administering system
US3496878A (en) * 1967-04-07 1970-02-24 Bio Medical Systems Inc System and apparatus for transfer of human fluids
US4231707A (en) * 1978-01-31 1980-11-04 Pilot Man-Nen-Hitsu Kabushiki Kaisha Fluid supplying device
US4365728A (en) * 1978-03-13 1982-12-28 Pilot Man-Nen-Hitsu Kabushiki Kaisha Liquid discharge apparatus
US4229299A (en) * 1978-03-22 1980-10-21 Hoechst Aktiengesellschaft Peristaltic dialysate solution pump
NL8303495A (en) * 1983-10-12 1985-05-01 Unilever Nv PERISTALTIC PUMP.
US4586882A (en) * 1984-12-06 1986-05-06 Baxter Travenol Laboratories, Inc. Tubing occluder pump
WO1986003561A1 (en) * 1984-12-06 1986-06-19 Baxter Travenol Laboratories, Inc. Tubing occluder pump
US4705464A (en) * 1986-05-09 1987-11-10 Surgidev Corporation Medicine pump
US4725205A (en) * 1987-01-30 1988-02-16 Fisher Scientific Group Inc. Peristaltic pump with cam action compensator
US4728265A (en) * 1987-01-30 1988-03-01 Fisher Scientific Group Inc. Peristaltic pump with cam action compensator
US4856972A (en) * 1988-06-09 1989-08-15 Fisher Scientific Co. Dual roller peristaltic pump
US4950136A (en) * 1989-08-14 1990-08-21 Hydro Systems Company Peristaltic pump
US5470211A (en) * 1993-08-12 1995-11-28 Stockert Instrumente Gmbh Roller pump
WO1999042726A1 (en) * 1998-02-19 1999-08-26 The University Of Melbourne Linearised peristaltic pump
US6413059B1 (en) 1998-02-19 2002-07-02 University Of Melbourne Linearized peristaltic pump
US6736617B2 (en) 2002-02-20 2004-05-18 Terumo Cardiovascular Systems Corporation Peristaltic pump having automatically adjusting bushing
US8663538B2 (en) 2009-02-12 2014-03-04 Picolife Technologies, Llc Method of making a membrane for use with a flow control system for a micropump
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