US1512294A - Hypodermic syringe - Google Patents

Hypodermic syringe Download PDF

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US1512294A
US1512294A US557937A US55793722A US1512294A US 1512294 A US1512294 A US 1512294A US 557937 A US557937 A US 557937A US 55793722 A US55793722 A US 55793722A US 1512294 A US1512294 A US 1512294A
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sleeve
ampul
syringe
needle
members
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US557937A
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Ernest H Marcy
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2407Ampoule inserted into the ampoule holder from the rear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485Ampoule holder connected to rest of syringe
    • A61M2005/2496Ampoule holder connected to rest of syringe via pivot

Definitions

  • the parts respectively mounting the needle and the pusher or ejector are or may be so connected as to prevent their separation from one another and from the ampul when in the assembled operative position, but which may be easily disengaged from the ampul to permit removal of the discharged ampul and the substitution of a full one.
  • Another ob'ect is to furnish a hypodermic instrument 0 the sort indicated which shall be of simple construction, capable of production at low cost and at the same time amply strong and rigid for the purposes 0t use, and to provide means in such an instrument for the inexpensive substitution of new needles for damaged ones. Still a fur-.
  • ther object is to provide for use in and as a part of the combination of such syringe an ampul having novel sealing and dischargin elements.
  • Figure 1 is a longitudinal section of a hypodermic syringe made according to this invention.
  • Figure 2 is a side elevation of the syringe showing the parts thereof disassembled.
  • Figure 3 is a longitudinal section on an enlarged scale of the ampul or medicine cartridge by itself. 7
  • Figure 4 is a sectional view of one of the sealing plugs of the ampul.
  • Figure 5 is an elevation of a modified form of needle-holding sleeve adapted to be used in the combination of Figures 1 and 2 in 1n the needle 1922. Serial No. 557,937.
  • Figure 6 is a perspective View of a modified construction of syringe with the parts thereof separated from one another.
  • the syringe comprises as its main parts a needlerholding sleeve 10 carrying a hypoder mic needle 11, a pusher-guiding sleeve 12, a.
  • the ampul 17 1 s a tube of glass or any other suitable material which is impervious to liquid, iscapable of being made sterile by heat, and is rigid enough to resist collapsing under lateral pressure in handling or any pressure applied endwise through the eject-, ing plunger in discharging the contents.
  • plugs 19 and 20 1 forming closures, one of which is adapted to be moved endwise by the pusher head 14 through the tube to expel the medicine.
  • 'l'hese plugs may be made of cork, rubber or other material which is impervious to the liquid, is capable of bein sterilized, and is adapted to make a liqui -tight joint'with' the walls of the ampul, while capable of being moved through the tube in the manner of a piston.
  • these requirements demand that the plugs should have considerable elasticity. They do not, howeyer, exclude the possibility of providing the plugs with a metallic or other surface covering in case the nature of the medicine requires that it be kept out of direct contact with the substance of which theplugs as a whole are made.
  • a suitable form for the bayonet joint cam slots is indicated in Figure 2.
  • the opposite ends of the tie-members are connected in any suitable way to the sleeve 12, being here shown as integral with such sleeve, but permissibly otherwise secured, either rigidly or pivotally.
  • the sleeve 12 is closed by a head or plug 23 which is soldered or otherwise rigidly secured Within the sleeve, and has an internal guideway for the pusher rod 13 and an external shoulder 24 on which the bar providing the finger holds 18 is seated, such bar having a hole in its middle through which the recured by soldering or any other suitable means.
  • the sleeve 10 is formed with a part 25 which is slotted so as to be springy and is of small enough internal diameter to engage the ampul and exert pressure on it to center it and hold it steady.
  • the adjacent part of the sleeve is made of larger diameter in order to admit between it and the ampul the inner heads on the pivot members 21 which overlap the walls of the slots 22 and retainsuch pivots in place.
  • the part of large diameter is between the needleholding end wall of the sleeve and the part 25, but the relative arrangement of these partsmay be reversed as shown by the modification in Figure 5, wherein the part which fits and resiliently embraces the ampul is the part nearest to the closed end of the sleeve, and the enlarged part containing the bayonet joint'slots is at the open end of the sleeve.
  • the end wall 26 of the sleeve. 10 has a central opening through which the needle may pass freely, and the needle carries a collar2'Z which rests on the inner side of this end wall whenin place.
  • hollow stem 28 may be provided to extend from the collar '27- surrounding the needle These slots have a portion.
  • the collar 27 is placed at a distance from the inner point ap- "proximately equal to, or slightly greater "than, the length of one of the plugs 19 or 20.
  • the inner point of the needle penetrates the plug at the adjacent end of the ampul and provides a passage for discharge of the medicine.
  • the plug 19 has a central depression or well 29 in its inner end and the distance from the collar 27 to the inner orifice of the needle is made approximately equal to the distance between the outer end of the plug and this recess, an arrangement which enables substantially all of the contents of the ampul to be discharged.
  • the inner end of the needle has been caused to penetrate the plug 19 by thus assembling the parts, and the head 14 of the pusher has been brought against the opposite plhg 20 and slightly en tered into the adjacent end of the ampul. Thereafter the syringe may be used in the ordinary manner to discharge its contents into the vein or tissues of a patientby, displace:v ment of the pusher. In being thus displaced the pusher-forces the plug 20 beforeit and said plug acts as a piston to displace the contents of the ampul and force said contents through the bo-re ofthe needlei; I
  • ampul may be sterilized, and after sterilization it is a sealed, sterile medicine package.
  • the sealing skirt When the ampul is to be used in the syringe, the sealing skirt may be torn off from the plugs, or the ampul may be inserted in the sleeves of the syringe without preliminary removal of these skirts, for the pressure applied to the piston plug by the pusher will be sufficient to tear this plug away from its skirt.
  • Plugs having skirts of the qualities necessary and sufiicient to serve the purposes here set forth may be made of vulcanized rubber of qualities well known to those acquainted with the art of rubber manufacture.
  • syringe just described has the characteristic that the sleeves 10 and 12 are permanently connected together with provision for limited separation. For some purposes this is a valuable feature. However, for other purposes a syringe of which the parts are entirely separable may be desired, and such a one is shown in Figure 6 as a modification of the invention.
  • the needle carrying sleeve 10 and the pusher-carrying sleeve 12 are provided entirely separate from one another, each having slots extending inwardly from itsopen end to divide its walls into spring tube-grip.
  • the tying device equivalent tothe tiemembers 16 is made of a piece of wire blent to form two parallel legs 16 with inwardly directed points or pivot ends 21 and its central loop portion 32 is bent over at ri ht angles to the plane of the legs 16*.
  • bends 33 are formed in some part of the legs in order to give elasticity and capacity for stretch in the longitudinal direction.
  • the tying device so made is assembled with the sleeve 10 by slipping its pivot ends into two of the oppositely located holes 31 in the latter, and then when the ampul has been inserted at one end into this sleeve, and the sleeve 12 has been passed over the other end of the ampul, the tying device is turned about its pivots and sprung over the sleeve 12 Its legs 16* then lie at opposite sides of the ampul and sleeve 12, and its ofi'set loop 32 surrounds the plunger but bears against the end wall of the sleeve, being of such radius and extent of olfset that it will occupy that position and serve as an abutment to prevent removal of the sleeve.
  • the resilience give-n by the bends 33 enables the abutment loo 32 thus to be placed across and removed rom the end of sleeve 12, and to exert pressure on such sleeve to hold it in place.
  • a hypodermic syringe adapted to receive and to discharge a sterile medicine package comprising end members adapted to be passed over the ends of such package, a tying device pivoted to one of said members and adapted to embrace the medicine package and tie the other of said end members to the first member, a hypodermic needle carried by one of said end members adapted to make communication with the interior of the package when so assembled, and an ejector associated with the other end member, the package having a plunger adapted to be displaced by said ejector for expelling the contents of the package.
  • a hypodermic syringe comprising a needle-carrying sleeve adapted to embrace one end of a medicine package, a plungercarrying member adapted to engage the opposite end of such package, and tie-members extending from one of the aforesaid. members and having pivotal and sliding connection with the other of said end members, whereby the members are adapted to be displaced for receiving a medicine pack age and then to be locked in assembled position with such package.
  • a sleeve adapted to receive and embrace one end of a medicine package, said sleeve having a. portion of approximately the same diameter as said package and provided with spring tongues to bear upon the package,

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Description

E. H. MARCY HYPODERMIG SYRINGE Filed May 2, 1922 INVENTOR 5.11. Marcy.
Patented Oct. 21,1924.-
ERNEST H. MARCY, 0E FRAMINGIIAM, MASSACHUSETTS.
OFFICE. I
. I HYronERMIo sYniNGE.
Application filed May '2,
To all whom may concern:
Be it known that I, ERNEST H. MARGY, a
citizen of the United States, residing at age or ampul containing the medicine, and
in which the parts respectively mounting the needle and the pusher or ejector are or may be so connected as to prevent their separation from one another and from the ampul when in the assembled operative position, but which may be easily disengaged from the ampul to permit removal of the discharged ampul and the substitution of a full one.
Another ob'ect is to furnish a hypodermic instrument 0 the sort indicated which shall be of simple construction, capable of production at low cost and at the same time amply strong and rigid for the purposes 0t use, and to provide means in such an instrument for the inexpensive substitution of new needles for damaged ones. Still a fur-.
ther object is to provide for use in and as a part of the combination of such syringe an ampul having novel sealing and dischargin elements.
These objects are accomplished b the hypodermic syringe which, with mo ifications,is described in the followmg specification and shown in the drawings accompanying the same. The invention consistsin such syringe and all modifications and equivalents thereofwithin the scope of the appended claims. I
In the drawings:-- 2 Figure 1 is a longitudinal section of a hypodermic syringe made according to this invention.
Figure 2is a side elevation of the syringe showing the parts thereof disassembled.
Figure 3 is a longitudinal section on an enlarged scale of the ampul or medicine cartridge by itself. 7
Figure 4 is a sectional view of one of the sealing plugs of the ampul.
Figure 5 is an elevation of a modified form of needle-holding sleeve adapted to be used in the combination of Figures 1 and 2 in 1n the needle 1922. Serial No. 557,937.
ing sleeve there shown. Figure 6 is a perspective View of a modified construction of syringe with the parts thereof separated from one another.
,Like reference characters designate the same parts in all the figures.
substitution for the particular needle-hold The syringe comprises as its main parts a needlerholding sleeve 10 carryinga hypoder mic needle 11, a pusher-guiding sleeve 12, a.
pusher rod 13 guided in the latter sleeve and having a head 14 on one end and a knob 15 onthe other, tie-members 16 connecting the sleeves 10 and 12, and an am-pul or medicine holding cartridge 17. With the plun ger-guiding sleeve may be combined finger holds. 18, or, in other words, abutments for receiving the reaction ofthe fingers of the operator when the. thumb is pressed upon the knob 15 in ejecting the medicinal'charge.
The ampul 17 1s a tube of glass or any other suitable material which is impervious to liquid, iscapable of being made sterile by heat, and is rigid enough to resist collapsing under lateral pressure in handling or any pressure applied endwise through the eject-, ing plunger in discharging the contents. In the ends of the ampul are plugs 19 and 20 1 forming closures, one of which is adapted to be moved endwise by the pusher head 14 through the tube to expel the medicine. 'l'hese plugs may be made of cork, rubber or other material which is impervious to the liquid, is capable of bein sterilized, and is adapted to make a liqui -tight joint'with' the walls of the ampul, while capable of being moved through the tube in the manner of a piston. In commercial practice these requirements demand that the plugs should have considerable elasticity. They do not, howeyer, exclude the possibility of providing the plugs with a metallic or other surface covering in case the nature of the medicine requires that it be kept out of direct contact with the substance of which theplugs as a whole are made.
I In assembling the ampul with the other duced part of the plug passes, and being setions so that they cannot accidentally be displaced from those positions. For this purpose the ends of the tie-members are connected with one of the sleeves, as 10, by pivots 21 which occupy bayonet jointslots 22 in the sleeve. extendim paralled to the axis of the sleeve and another portion so'inclined to su chlaxis as to pull upon theztie-members with acam action and also to lock them When the pivots;
reach or approach the ends of such, inclined portions. A suitable form for the bayonet joint cam slots is indicated in Figure 2. There are preferablytwo such tie-members and slots arranged at opposite sides of instrument, or at least so separated that the ampul may pass between them. The opposite ends of the tie-members are connected in any suitable way to the sleeve 12, being here shown as integral with such sleeve, but permissibly otherwise secured, either rigidly or pivotally.
Referring to the sleeve 12 more in detail, the latter is closed by a head or plug 23 which is soldered or otherwise rigidly secured Within the sleeve, and has an internal guideway for the pusher rod 13 and an external shoulder 24 on which the bar providing the finger holds 18 is seated, such bar having a hole in its middle through which the recured by soldering or any other suitable means. The sleeve 10 is formed with a part 25 which is slotted so as to be springy and is of small enough internal diameter to engage the ampul and exert pressure on it to center it and hold it steady. The adjacent part of the sleeve is made of larger diameter in order to admit between it and the ampul the inner heads on the pivot members 21 which overlap the walls of the slots 22 and retainsuch pivots in place. In the form of the invention shown in Figures 1 and 2, the part of large diameter is between the needleholding end wall of the sleeve and the part 25, but the relative arrangement of these partsmay be reversed as shown by the modification in Figure 5, wherein the part which fits and resiliently embraces the ampul is the part nearest to the closed end of the sleeve, and the enlarged part containing the bayonet joint'slots is at the open end of the sleeve.
Whatever I may be the form of sleeve I preferably make it separable from theneedle in orde'r'that the latter may beremoved when damaged and a new one substituted. Accordingly the end wall 26 of the sleeve. 10 has a central opening through which the needle may pass freely, and the needle carries a collar2'Z which rests on the inner side of this end wall whenin place. A
hollow stem 28 may be provided to extend from the collar '27- surrounding the needle These slots have a portion.
ing points at both ends and the collar 27 is placed at a distance from the inner point ap- "proximately equal to, or slightly greater "than, the length of one of the plugs 19 or 20. Hence, when the ampul is inserted in the sleeve 10, after the needle has been placed therein, the inner point of the needle penetrates the plug at the adjacent end of the ampul and provides a passage for discharge of the medicine. Preferably the plug 19 has a central depression or well 29 in its inner end and the distance from the collar 27 to the inner orifice of the needle is made approximately equal to the distance between the outer end of the plug and this recess, an arrangement which enables substantially all of the contents of the ampul to be discharged.
It will be apparent that when the parts of the syringe are displaced or opened as shown in Figure 5, a sterile filled ampul may be placed in the syringe without exposing its contents to septic matter. After one end of the ampul has been placed in the sleeve 10, the sleeve 12, with the plunger fully withdrawn, may be passed over the other end of the ampul and then the parts all firmly locked and secured together by shifting the pivot pin into the inclined parts of the bayonet joint cam slots as far as possible. The ampul is then gripped between the heads of the two sleeves and the. whole syringe is a firm and rigid unit. The inner end of the needle has been caused to penetrate the plug 19 by thus assembling the parts, and the head 14 of the pusher has been brought against the opposite plhg 20 and slightly en tered into the adjacent end of the ampul. Thereafter the syringe may be used in the ordinary manner to discharge its contents into the vein or tissues of a patientby, displace:v ment of the pusher. In being thus displaced the pusher-forces the plug 20 beforeit and said plug acts as a piston to displace the contents of the ampul and force said contents through the bo-re ofthe needlei; I
An important advantage which I claim as part of this inventionrelates to --the lampul. and its plugs as parts of the combination just described. These plugs. are both-closures and antiseptic sealing means for the ampul, and eitherof them is adapted'to serve as an ejecting piston. Thus theyare made to fitthe boreof the ampulwithcapac-, ity for sliding ven'dwise throughsuch bore. Their antiseptic sealing function is accomplished' by providing each plug with a thin tubular extension or skirt 30, as shown in detail in Figure 4,"which skirt is made of elastic, flexible and at the same time sufiiand fitting the opening in end Wall 26, but ciently tough material. After the plugs have been inserted in the ends of the ampul, this skirt is rolled back over the outer walls. as permitted by its flexibility, and when thus placed its resilience causes it to hug the outer walls of the ampul and prevent entrance of any micro-organisms. \Vhen so closed the ampul may be sterilized, and after sterilization it is a sealed, sterile medicine package.
When the ampul is to be used in the syringe, the sealing skirt may be torn off from the plugs, or the ampul may be inserted in the sleeves of the syringe without preliminary removal of these skirts, for the pressure applied to the piston plug by the pusher will be sufficient to tear this plug away from its skirt. Plugs having skirts of the qualities necessary and sufiicient to serve the purposes here set forth may be made of vulcanized rubber of qualities well known to those acquainted with the art of rubber manufacture.
The form of syringe just described has the characteristic that the sleeves 10 and 12 are permanently connected together with provision for limited separation. For some purposes this is a valuable feature. However, for other purposes a syringe of which the parts are entirely separable may be desired, and such a one is shown in Figure 6 as a modification of the invention. Here the needle carrying sleeve 10 and the pusher-carrying sleeve 12 are provided entirely separate from one another, each having slots extending inwardly from itsopen end to divide its walls into spring tube-grip.
ping tongues and these slots terminate in enlarged holes 31, at least as to one of the sleeves, and preferably the sleeve 10 I The tying device equivalent tothe tiemembers 16 is made of a piece of wire blent to form two parallel legs 16 with inwardly directed points or pivot ends 21 and its central loop portion 32 is bent over at ri ht angles to the plane of the legs 16*. Preferably bends 33 are formed in some part of the legs in order to give elasticity and capacity for stretch in the longitudinal direction. The tying device so made is assembled with the sleeve 10 by slipping its pivot ends into two of the oppositely located holes 31 in the latter, and then when the ampul has been inserted at one end into this sleeve, and the sleeve 12 has been passed over the other end of the ampul, the tying device is turned about its pivots and sprung over the sleeve 12 Its legs 16* then lie at opposite sides of the ampul and sleeve 12, and its ofi'set loop 32 surrounds the plunger but bears against the end wall of the sleeve, being of such radius and extent of olfset that it will occupy that position and serve as an abutment to prevent removal of the sleeve. The resilience give-n by the bends 33 enables the abutment loo 32 thus to be placed across and removed rom the end of sleeve 12, and to exert pressure on such sleeve to hold it in place.
What I claim and desire to secure by Letters Patent is:
l. A hypodermic syringe adapted to receive and to discharge a sterile medicine package comprising end members adapted to be passed over the ends of such package, a tying device pivoted to one of said members and adapted to embrace the medicine package and tie the other of said end members to the first member, a hypodermic needle carried by one of said end members adapted to make communication with the interior of the package when so assembled, and an ejector associated with the other end member, the package having a plunger adapted to be displaced by said ejector for expelling the contents of the package.
2. A hypodermic syringe comprising a needle-carrying sleeve adapted to embrace one end of a medicine package, a plungercarrying member adapted to engage the opposite end of such package, and tie-members extending from one of the aforesaid. members and having pivotal and sliding connection with the other of said end members, whereby the members are adapted to be displaced for receiving a medicine pack age and then to be locked in assembled position with such package.
3. In a hypodermic syringe, a sleeve adapted to receive and embrace one end of a medicine package, said sleeve having a. portion of approximately the same diameter as said package and provided with spring tongues to bear upon the package,
and'having another portion of larger diameter provided with cam slots.
In testimony whereof I have affixed my signature.
ERNEST H. MARCiY.
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Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2537550A (en) * 1946-10-20 1951-01-09 Roos Walther Paste-dispensing syringe for medical purposes
US2561825A (en) * 1947-08-08 1951-07-24 William A Sherbondy Dispensing device for calking material and the like
US2602571A (en) * 1950-02-21 1952-07-08 William A Sherbondy Dispensing device for calking material and the like
US2602570A (en) * 1947-10-06 1952-07-08 William A Sherbondy Dispensing device for cartridges of calking material and the like
US2672142A (en) * 1947-09-30 1954-03-16 Harold M Baron Breech loading syringe for use with hypodermic medication cartridges
US2705008A (en) * 1947-09-30 1955-03-29 Morton Newburger Medication cartridge-needle-needle guard unit for hypodermic syringe
US2871858A (en) * 1957-10-30 1959-02-03 American Home Prod Hinged syringe body
US4968303A (en) * 1988-09-27 1990-11-06 Eli Lilly And Company Hypodermic syringe holder
US6673035B1 (en) 1999-10-22 2004-01-06 Antares Pharma, Inc. Medical injector and medicament loading system for use therewith
US20050197650A1 (en) * 2004-03-05 2005-09-08 Hirohumi Sugimoto Administration apparatus for medical use
US20110046603A1 (en) * 2009-08-21 2011-02-24 Becton Dickinson France S.A.S. Syringe Assembly with Pivoting Plunger and Integral Tip Guard
US20110046560A1 (en) * 2009-08-21 2011-02-24 Becton Dickinson France S.A.S. Magnifying Collapsed Plunger Rod
US20140046266A1 (en) * 2011-05-06 2014-02-13 Sanofi-Aventis Deutschland Gmbh Drug delivery device and cartridge holder for a drug delivery device
US8657793B2 (en) 2011-09-30 2014-02-25 Becton Dickinson France, S.A.S Space saving plunger cap and rod assembly
US8915889B2 (en) 2008-08-05 2014-12-23 Antares Pharma, Inc. Multiple dosage injector
US8945063B2 (en) 2009-03-20 2015-02-03 Antares Pharma, Inc. Hazardous agent injection system
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US20160193421A1 (en) * 2013-09-10 2016-07-07 Sanofi Drug delivery device
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9707354B2 (en) 2013-03-11 2017-07-18 Antares Pharma, Inc. Multiple dosage injector with rack and pinion dosage system
US9744302B2 (en) 2013-02-11 2017-08-29 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9808582B2 (en) 2006-05-03 2017-11-07 Antares Pharma, Inc. Two-stage reconstituting injector
US9950125B2 (en) 2012-04-06 2018-04-24 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions

Cited By (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2537550A (en) * 1946-10-20 1951-01-09 Roos Walther Paste-dispensing syringe for medical purposes
US2561825A (en) * 1947-08-08 1951-07-24 William A Sherbondy Dispensing device for calking material and the like
US2672142A (en) * 1947-09-30 1954-03-16 Harold M Baron Breech loading syringe for use with hypodermic medication cartridges
US2705008A (en) * 1947-09-30 1955-03-29 Morton Newburger Medication cartridge-needle-needle guard unit for hypodermic syringe
US2602570A (en) * 1947-10-06 1952-07-08 William A Sherbondy Dispensing device for cartridges of calking material and the like
US2602571A (en) * 1950-02-21 1952-07-08 William A Sherbondy Dispensing device for calking material and the like
US2871858A (en) * 1957-10-30 1959-02-03 American Home Prod Hinged syringe body
US4968303A (en) * 1988-09-27 1990-11-06 Eli Lilly And Company Hypodermic syringe holder
US6673035B1 (en) 1999-10-22 2004-01-06 Antares Pharma, Inc. Medical injector and medicament loading system for use therewith
US20040134563A1 (en) * 1999-10-22 2004-07-15 Antares Pharma, Inc. Medical injector and medicament loading system for use therewith
US7341575B2 (en) 1999-10-22 2008-03-11 Antares Pharma, Inc. Medical injector and medicament loading system for use therewith
US9737670B2 (en) 2002-02-11 2017-08-22 Antares Pharma, Inc. Intradermal injector
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