TW337522B - Benzazepine-, benzoxazepine- and benzothiazepine-n-acetic acid derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents

Benzazepine-, benzoxazepine- and benzothiazepine-n-acetic acid derivatives, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
TW337522B
TW337522B TW085102367A TW85102367A TW337522B TW 337522 B TW337522 B TW 337522B TW 085102367 A TW085102367 A TW 085102367A TW 85102367 A TW85102367 A TW 85102367A TW 337522 B TW337522 B TW 337522B
Authority
TW
Taiwan
Prior art keywords
hydrogen
benzoxazepine
benzothiazepine
benzazepine
preparation
Prior art date
Application number
TW085102367A
Other languages
Chinese (zh)
Inventor
Waldeck Harald
Holtje Dagmar
Messinger Josef
Antel Jochen
Wurl Michael
Thormahlen Dirk
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Priority to TW085102367A priority Critical patent/TW337522B/en
Application granted granted Critical
Publication of TW337522B publication Critical patent/TW337522B/en

Links

Landscapes

  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

A compound with neutral endopeptidase (NEP) inhibitory activity corresponding to the formula I (I) in which R1 is a lower alkoxy-lower-alkyl group whose lower alkoxy radical is substituted by a lower alkoxy group, or a phenyl-lower-alkyl or phenyloxy-lower-alkyl group which can optionally be substituted in the phenyl ring by lower alkyl, lower alkoxy or halogen, or a naphthyl-lower-alkyl group, A is CH2, O or S, R2 is hydrogen or halogen, R3 is hydrogen or halogen, R4 is hydrogen or a group forming a biolabile ester, and R5 is hydrogen or a group forming a biolabile ester, and the physiologically acceptable acid addition salts thereof.
TW085102367A 1996-02-28 1996-02-28 Benzazepine-, benzoxazepine- and benzothiazepine-n-acetic acid derivatives, process for their preparation and pharmaceutical compositions containing them TW337522B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TW085102367A TW337522B (en) 1996-02-28 1996-02-28 Benzazepine-, benzoxazepine- and benzothiazepine-n-acetic acid derivatives, process for their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW085102367A TW337522B (en) 1996-02-28 1996-02-28 Benzazepine-, benzoxazepine- and benzothiazepine-n-acetic acid derivatives, process for their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
TW337522B true TW337522B (en) 1998-08-01

Family

ID=58263204

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085102367A TW337522B (en) 1996-02-28 1996-02-28 Benzazepine-, benzoxazepine- and benzothiazepine-n-acetic acid derivatives, process for their preparation and pharmaceutical compositions containing them

Country Status (1)

Country Link
TW (1) TW337522B (en)

Similar Documents

Publication Publication Date Title
CA2172354A1 (en) Benzazepine-, benzoxazepine- and benzothiazepine-n-acetic acid derivatives, process for their preparation and pharmaceutical compositions containing them
AP9701039A0 (en) Derivatives of 2- (2-oxo-ethlidene)-imidazolidin-4-one.
AU557691B2 (en) 2-penem antibiotics and their oxa-aza-, and carba analogues
UA39869C2 (en) ASPARTAM DERIVATIVES OR THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS, THE METHOD OF OBTAINING THEM AND THE SWEETENING COMPOSITION
MY115679A (en) Process for preparing intermediates to florfenicol
PH20768A (en) New diazabicyclo-(3.3.1)-nonanes and a process for the preparation thereof
IL57577A0 (en) 1,2-dihydroquinolin-2-one derivatives,process for their preparation and pharmaceutical compositions containing the same
MY117090A (en) Substituted benzamidines, their preparation and their use as pharmaceutical compounds
AU2267495A (en) Benzamide derivatives as vasopressin antagonists
WO1999020639A3 (en) NOVEL 3,6-HEMIKETALS FROM THE CLASS OF 9a-AZALIDES
ES8507090A1 (en) 1,5-Benzothiazepines with cardiovascular utility, and pharmaceutical compositions containing them
IL68093A0 (en) Theophyllinyl-alkyl-oxadiazoles,process for the preparation thereof and pharmaceutical compositions containing them
FI893901A (en) Process for the preparation of tetracyclic antidepressants
ES2016017A6 (en) 1,1-dioxo-cephem-4-carbothiolic acid derivatives.
HK1023346A1 (en) Novel substituted tetrahyropyridine derivatives, method of preparation and pharmaceutical compositions containing them
ATE21101T1 (en) N-IMINOPYRIDINIUM BETAIN DERIVATIVES, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCTS.
ATE42292T1 (en) IMIDAZO(1,2-C)PYRIMIDINES AND THEIR SALTS, PROCESSES FOR THEIR PRODUCTION, THEIR USE AS MEDICINAL PRODUCTS AND PREPARATIONS CONTAINING THEM.
ATE127465T1 (en) ISOINDOLINONE DERIVATIVE, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME.
TW337522B (en) Benzazepine-, benzoxazepine- and benzothiazepine-n-acetic acid derivatives, process for their preparation and pharmaceutical compositions containing them
ATE30724T1 (en) CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
ATE37368T1 (en) BENZOTHIAZOLONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
NZ332687A (en) use of 1-methyl-carbapenem derivatives as anti-helicobacter pylori agents
AU658175B2 (en) Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients
ES8105330A1 (en) Thiazolo (2,3-b) benzo (and azabenzo) thiazole derivatives, process for their preparation and pharmaceutical compositions containing them.
ZA842423B (en) Compounds with antiinflammatory activity,process for preparation thereof and pharmaceutical compositions therefrom

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees