SU1291153A1 - Method of treatment of neurologic disturbances caused by heavy craniocerebral trauma - Google Patents

Abstract

The invention relates to medicine, namely to neurosurgery, neuro-traumatology and neurology. The purpose of the invention is a more complete and faster restoration of motor, speech and intellectual functions. For this, retrograde catheterization of the common carotid artery is performed on the side of the dominant pathology of the brain through the superficial temporal or occipital arteries. If retrograde catheterization is not possible, antiretrograde is performed by percutaneous puncture of the common carotid artery in the neck. A system for intravascular injection of drugs is attached to the catheter, with continuous and consistently administered drug infusates daily for 7–30 days: aminophylline with novocaine, contrical, cocarboxylase in a mixture with 1b% glucose and insulin, hematosis, then re-aminophiline with novocaine, Cavinton and piracetam, every other day. The administration of hemodesis alternates with reopolyglucine, and from 4 days the trim is replaced — with Cavinton and cococarboxylase on piracetam. The doses of aminophylline and Novocain vary depending on the patient’s weight, level Blood pressure and severity of tachycardia. Doses of cocarboxylase and insulin are determined by severity of acidosis and diencephalic-catabolic syndrome. The infusion cycle is repeated until a clear clinical effect is obtained. with S (L

Description

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This invention relates to medicine, namely to neurosurgery, neuro-traumatology and neurology.

The purpose of the invention is a more complete and rapid restoration of motor, speech and intellectual functions by continuous and sequential intracarotid administration of euphylline with novocaine, contrikap, cocarboxylae in a mixture with 10% glucose and insulin, hemodesis in alternation for 7-30 days. a day later with reopolyglucic nome, again zufillin with novocaine, then cavinton and piracetam, on the fourth day the contrical was replaced with cavinton, and cocarboxylase with piracetam.

The method is carried out as follows.

A retrograde catheterization of the common carotid artery is performed on the side of the dominant brain pathology through the superficial temporal or occipital arteries. If retrograde catheterization is not possible, antiretrograde catheter insertion is performed by percutaneous puncture of the common carotid artery in the neck. A system for intravascular injection of drugs is attached to the catheter through which the following drug infusates are continuously and consistently administered.

Infusat 1 - 2.4% solution of aminophylline, 7-10 ml, 0.5% solution of novocaine 20-40 ml, isotonic solution of sodium chloride to 200 ml. Doses of aminophylline and novocaine vary depending on the patient's weight, blood pressure level and severity of tachycardia. The infusate is administered within 3 hours.

Infusat 2 - counter 10000120000 U per 200 ml of 5% glucose or 5% aminocaproic acid 100-150 ml are administered in the presence of foci of contusion or crush of the brain in the acute period. The infusate is administered within 3 hours.

Infusat 3 - cocarboxylase 50-200 mg, 10% glucose 200 ml, insulin 5 Ed. The dose is determined by the degree of severity of acidosis and the severity of the dysphalic-catabolic syndrome. The infusate is administered within 4 hours.

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Infusion 4 - hemodez 400 ml or reopigluglukin 400 ml is administered within 4 hours.

Infusat 5 - repeated administration of euphylline with novocaine in the same doses on an isotonic solution of sodium chloride for 3 hours.

Infusion 6 - Cavinton 2–4 ml per 200 ml of 5% glucose is administered within 4 hours.

An infusate of 7-20% pyracetam 10-30 ml per 200 ml of isotonic solution of sodium chloride or 5% glucose is administered within 3 hours.

The next day, the cycle of infusions is repeated until a clear effect is obtained. From 4-5 days, the contry in the infusate 2 is replaced with 2 ml of cavinthone, and instead of infusion 3, piracetam is added in an isotonic solution of sodium chloride or 5% glucose.

Example. The patient, after resection of craniotomy in the left fronto-parietal-temporal region, the removal of acute subdural hydroma and a crush site of 2.5 3x2 cm, was performed in the basal regions of the temporal lobe for a long time. infusion according to the proposed scheme. Infusates were administered at a rate of 10-16 drops per minute. In addition to the infusion, the patient was injected with penicillin 500,000 IU intramuscularly 6 times a day and 25 mg of aminazine overnight. On the second day, the patient began to pronounce individual words, on the third - short phrases, perform simple tasks, on the fourth day the weakness in the right extremities completely disappeared, the asymmetry of the face decreased. On the eleventh day of infusion, the patient's condition is satisfactory, adequate, no speech disturbances, no paresis. Due to the complete recovery of speech and motor functions, the infusion was discontinued for 11 days.

Claims (1)

Invention Formula A method for treating neurological disorders caused by severe traumatic brain injury, including intracarotid infusion of vasoactive, antienzyme and improves the rheological properties of blood preparations to normalize neurological status, characterized in that 31291153 4 restoration of motor, speech, eufillin with novacaine, cavin intellectual functions, sickle and piracetam, after a day after introducing the current of days, the introduction of hemodezis alternated with reopolyglucid eufillin with novocaine, contrin, and from the fourth day feces, cocarboxylase in a mixture with 10% 5 substitution for Cavinton and cocarboxyglucose and insulin, hemodez, then for Piracetam.