SI0892792T1 - Process to prepare oxazolidinones - Google Patents

Process to prepare oxazolidinones

Info

Publication number: SI0892792T1
Authority: SI; Slovenia
Prior art keywords: reacting; substituted; oxazolidinone; oxazolidinones; prepare
Prior art date: 1996-04-11

Application number

SI9730273T

Other languages

English (en)

Slovenian (sl)

Inventor

Bruce A. Pearlman

William R. Perrault

Michael R. Barbachyn

Peter R. Manninen

Dana S. Toops

David J. Houser

Thomas J. Fleck

Original Assignee

Pharmacia & Upjohn Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-11

Filing date

1997-03-28

Publication date

2002-06-30

1997-03-28 Application filed by Pharmacia & Upjohn Company filed Critical Pharmacia & Upjohn Company

2002-06-30 Publication of SI0892792T1 publication Critical patent/SI0892792T1/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SI9730273T 1996-04-11 1997-03-28 Process to prepare oxazolidinones SI0892792T1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1549996P	1996-04-11	1996-04-11
PCT/US1997/003458 WO1997037980A1 (en)	1996-04-11	1997-03-28	Process to prepare oxazolidinones

Publications (1)

Publication Number	Publication Date
SI0892792T1 true SI0892792T1 (en)	2002-06-30

Family

ID=21771765

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9730273T SI0892792T1 (en)	1996-04-11	1997-03-28	Process to prepare oxazolidinones

Country Status (25)

Country	Link
US (1)	US5837870A (xx)
EP (2)	EP0892792B1 (xx)
JP (2)	JP2000508312A (xx)
KR (1)	KR100530297B1 (xx)
CN (3)	CN1319952C (xx)
AT (2)	ATE383347T1 (xx)
AU (1)	AU706117B2 (xx)
CA (1)	CA2248143C (xx)
CZ (2)	CZ298060B6 (xx)
DE (2)	DE69738457T2 (xx)
DK (2)	DK0892792T3 (xx)
ES (2)	ES2298198T3 (xx)
HK (2)	HK1018785A1 (xx)
HU (1)	HUP0500044A3 (xx)
NO (2)	NO311837B1 (xx)
NZ (1)	NZ332278A (xx)
PL (1)	PL192691B1 (xx)
PT (2)	PT1114819E (xx)
RU (1)	RU2176643C2 (xx)
SG (1)	SG85683A1 (xx)
SI (1)	SI0892792T1 (xx)
SK (1)	SK284703B6 (xx)
TW (1)	TW449593B (xx)
WO (1)	WO1997037980A1 (xx)
ZA (1)	ZA972983B (xx)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9601666D0 (en) *	1996-01-27	1996-03-27	Zeneca Ltd	Chemical compounds
GB9702213D0 (en)	1996-02-24	1997-03-26	Zeneca Ltd	Chemical compounds
GB9609919D0 (en)	1996-05-11	1996-07-17	Zeneca Ltd	Chemical compounds
GB9717804D0 (en)	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9717807D0 (en)	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9725244D0 (en)	1997-11-29	1998-01-28	Zeneca Ltd	Chemical compounds
HUP0103082A3 (en)	1998-06-05	2002-12-28	Astrazeneca Ab	Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
DE69933526D1 (de) *	1998-12-07	2006-11-23	Takasago Perfumery Co Ltd	Verfahren zur Herstellung von optisch aktiven Oxazolidinonderivate
PL349911A1 (en)	1999-02-01	2002-10-07	Upjohn Co	Process to prepare cyclic-sulfur fluorine containing oxazolidinones
US6608081B2 (en) *	1999-08-12	2003-08-19	Ortho-Mcneil Pharmaceutical, Inc.	Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6413981B1 (en)	1999-08-12	2002-07-02	Ortho-Mcneil Pharamceutical, Inc.	Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6297242B1 (en)	1999-08-12	2001-10-02	Ortho-Mcneil Pharmaceutical, Inc.	N-substituted amidine and guanidine oxazolidinone antibacterials and methods of use thereof
GB9928568D0 (en)	1999-12-03	2000-02-02	Zeneca Ltd	Chemical compounds
US6518285B2 (en)	1999-12-21	2003-02-11	Ortho Mcneil Pharmaceutical, Inc.	Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
US6444813B2 (en)	2000-02-02	2002-09-03	Pharmacia & Upjohn Company	Linezolid-crystal form II
AR027261A1 (es) *	2000-02-02	2003-03-19	Upjohn Co	Linezolid forma cristalina ii
MY127336A (en)	2000-03-22	2006-11-30	Upjohn Co	Container for linezolid iv solution
US6514529B2 (en)	2000-03-22	2003-02-04	Pharmacia & Upjohn Company	Oxazolidinone tablet formulation
GB0009803D0 (en) *	2000-04-25	2000-06-07	Astrazeneca Ab	Chemical compounds
DK1301207T3 (da)	2000-06-30	2005-10-10	Pharmacia & Upjohn Co Llc	Sammensætninger til behandling af bakterieinfektioner indeholdende en oxazolidinonforbindelse, sulbactam og ampicillin
PE20020300A1 (es) *	2000-08-22	2002-05-10	Pharmacia Corp	Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco
US6288239B1 (en)	2000-09-19	2001-09-11	Board Of Trustees Operating Michigan State University	5-trityloxymethyl-oxazolidinones and process for the preparation thereof
AR031135A1 (es)	2000-10-10	2003-09-10	Upjohn Co	Composiciones de antibiotico topico para el tratamiento de infecciones oculares
DE60212959T2 (de) *	2001-04-07	2007-02-15	Astrazeneca Ab	Eine sulfonimid-gruppe enthaltende oxazolidinone als antibiotika
ATE374463T1 (de)	2001-04-20	2007-10-15	Pharmacia & Upjohn Co Llc	Verfahren zur herstellung von oxazolidinonen
ES2186550B2 (es) *	2001-06-27	2003-11-16	Vita Lab	Nuevos derivados de oxazolidinonas como antibacterianos.
US7390825B1 (en) *	2001-10-18	2008-06-24	Board Of Trustees Of Michigan State University	Process for the preparation of oxazolidinones and method of use thereof
WO2003072141A1 (en) *	2002-02-22	2003-09-04	Pharmacia Corporation	Ophthalmic antibiotic drug formulations containing a cyclodextrin compound and cetyl pyridinium chloride
AR038575A1 (es) *	2002-02-22	2005-01-19	Pharmacia Corp	Formulacion oftalmica con nueva composicion de goma
HUE051230T2 (hu)	2003-10-16	2021-03-01	Symed Labs Ltd	Linezolid kristályos formája
PL1737850T3 (pl)	2004-04-19	2008-02-29	Symed Labs Ltd	Nowy sposób wytwarzania linezolidu i związków pokrewnych
DE602004020812D1 (de)	2004-07-20	2009-06-04	Symed Labs Ltd	Neue zwischenprodukte für linezolid und verwandte verbindungen
EP2007740A1 (en) *	2006-04-07	2008-12-31	Pfizer Products Incorporated	Process for preparing linezolid
CN100395270C (zh) *	2006-05-25	2008-06-18	湖北大学	线型聚苯乙烯支载的(4s)-5,5-二取代基噁唑烷酮及其制备方法和用途
EP2033960A3 (en) *	2007-09-04	2009-04-29	Dipharma Francis S.r.l.	Linezolid crystalline hydrate form and linezolid salts
WO2009032294A2 (en) *	2007-09-06	2009-03-12	Teva Pharmaceutical Industries Ltd.	Processes for the preparation of a linezolid intermediate, linezolid hydroxide
EP2163547A1 (en)	2008-09-16	2010-03-17	Unión Químico Farmacéutica, S.A. (UQUIFA)	Process for the preparation of an oxazolidinone antibacterial agent and intermediates thereof
JP5561462B2 (ja) *	2009-09-17	2014-07-30	日東化成株式会社	漁網防汚塗料組成物、該組成物を用いて形成される防汚塗膜、該塗膜の形成方法、および該塗膜を表面に有する漁網、漁網用具又は水中構造物
WO2011077310A1 (en) *	2009-12-26	2011-06-30	Alembic Limited	Process for the preparation of linezolid
CN102822167A (zh)	2010-01-04	2012-12-12	埃南蒂亚有限公司	用于制备利伐沙班的方法及其中间体
EP2603506A1 (en)	2010-08-11	2013-06-19	Synthon BV	Process for making linezolid
WO2012019632A1 (en)	2010-08-11	2012-02-16	Synthon B.V.	Process for making linezolid
US20130296569A1 (en)	2010-11-03	2013-11-07	Vijaykumar Jagdishwar Patil	Process for the preparation of phosphoric acid mono-(1--4-methoxymethyl-piperidin-4-yl) ester
WO2012094622A2 (en) *	2011-01-07	2012-07-12	The Regents Of The University Of California	Amination of aryl alcohol derivatives
CN102153521B (zh) *	2011-01-31	2012-09-12	宁波市鄞州百特佳医药科技有限公司	一种用于制备利奈唑胺的中间体及其制备方法
CN103402990A (zh)	2011-02-24	2013-11-20	李药业有限公司	无水利奈唑胺晶型-ii
EP2595968B1 (en)	2011-02-24	2015-09-09	Lee Pharma Limited	Novel process for preparation of linezolid and its novel intermediates
CN102311402B (zh) *	2011-07-18	2013-08-21	苏州敬业医药化工有限公司	3-取代苯基-5-羟甲基噁唑烷-2-酮的制备方法
CN102321042B (zh) *	2011-07-18	2013-12-04	苏州敬业医药化工有限公司	3-取代苯基-5-羟甲基噁唑烷-2-酮的制备方法
WO2013072923A1 (en)	2011-09-19	2013-05-23	Cadila Healthcare Limited	Process for the preparation of crystalline linezolid
US20150025236A1 (en)	2012-01-24	2015-01-22	Jubilant Life Sciences Limited	Process for the preparation of stable crystalline form-i of linezolid, substantially free of residual solvent
CN103626712B (zh) *	2012-08-23	2016-06-01	重庆药友制药有限责任公司	一种用于制备利奈唑胺的中间体及其制备方法
ES2603252T3 (es)	2012-11-09	2017-02-24	Synthon Bv	Proceso para preparar linezolid
WO2015173664A1 (en)	2014-05-14	2015-11-19	Wockhardt Limited	Process for the preparation of (5s)-n-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide

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1997
- 1997-03-28 CZ CZ0287198A patent/CZ298060B6/cs not_active IP Right Cessation
- 1997-03-28 JP JP9536189A patent/JP2000508312A/ja not_active Ceased
- 1997-03-28 DE DE69738457T patent/DE69738457T2/de not_active Expired - Fee Related
- 1997-03-28 SK SK1336-98A patent/SK284703B6/sk unknown
- 1997-03-28 AT AT01302264T patent/ATE383347T1/de not_active IP Right Cessation
- 1997-03-28 DK DK97915865T patent/DK0892792T3/da active
- 1997-03-28 CN CNB031594743A patent/CN1319952C/zh not_active Expired - Fee Related
- 1997-03-28 PT PT01302264T patent/PT1114819E/pt unknown
- 1997-03-28 SI SI9730273T patent/SI0892792T1/xx unknown
- 1997-03-28 RU RU98120398/04A patent/RU2176643C2/ru not_active IP Right Cessation
- 1997-03-28 EP EP97915865A patent/EP0892792B1/en not_active Expired - Lifetime
- 1997-03-28 NZ NZ332278A patent/NZ332278A/xx unknown
- 1997-03-28 ES ES01302264T patent/ES2298198T3/es not_active Expired - Lifetime
- 1997-03-28 CN CN97193658A patent/CN1082953C/zh not_active Expired - Fee Related
- 1997-03-28 SG SG9905133A patent/SG85683A1/en unknown
- 1997-03-28 AU AU23182/97A patent/AU706117B2/en not_active Ceased
- 1997-03-28 EP EP01302264A patent/EP1114819B1/en not_active Expired - Lifetime
- 1997-03-28 CA CA002248143A patent/CA2248143C/en not_active Expired - Fee Related
- 1997-03-28 DK DK01302264T patent/DK1114819T3/da active
- 1997-03-28 KR KR10-2004-7009934A patent/KR100530297B1/ko not_active IP Right Cessation
- 1997-03-28 PT PT97915865T patent/PT892792E/pt unknown
- 1997-03-28 HU HU0500044A patent/HUP0500044A3/hu unknown
- 1997-03-28 CZ CZ2007-88A patent/CZ200788A3/cs unknown
- 1997-03-28 US US08/828,923 patent/US5837870A/en not_active Expired - Fee Related
- 1997-03-28 ES ES97915865T patent/ES2166073T3/es not_active Expired - Lifetime
- 1997-03-28 WO PCT/US1997/003458 patent/WO1997037980A1/en active IP Right Grant
- 1997-03-28 CN CNB011330031A patent/CN1167701C/zh not_active Expired - Fee Related
- 1997-03-28 AT AT97915865T patent/ATE209193T1/de not_active IP Right Cessation
- 1997-03-28 DE DE69709718T patent/DE69709718T2/de not_active Expired - Fee Related
- 1997-03-28 PL PL329295A patent/PL192691B1/pl not_active IP Right Cessation
- 1997-04-02 TW TW086104216A patent/TW449593B/zh not_active IP Right Cessation
- 1997-04-08 ZA ZA972983A patent/ZA972983B/xx unknown
1998
- 1998-10-09 NO NO19984737A patent/NO311837B1/no unknown
1999
- 1999-09-03 HK HK99103839A patent/HK1018785A1/xx not_active IP Right Cessation
2001
- 2001-10-26 NO NO20015253A patent/NO312728B1/no unknown
2004
- 2004-06-16 HK HK04104332A patent/HK1061241A1/xx not_active IP Right Cessation
2008
- 2008-03-04 JP JP2008053675A patent/JP2008239621A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
US5837870A (en)	1998-11-17
SK133698A3 (en)	1999-06-11
CN1319952C (zh)	2007-06-06
DE69738457T2 (de)	2008-12-24
HK1061241A1 (en)	2004-09-10
NO20015253L (no)	1998-12-09
EP1114819A1 (en)	2001-07-11
ZA972983B (en)	1998-10-08
CN1167701C (zh)	2004-09-22
ES2166073T3 (es)	2002-04-01
CN1381454A (zh)	2002-11-27
NO312728B1 (no)	2002-06-24
EP0892792B1 (en)	2001-11-21
TW449593B (en)	2001-08-11
EP1114819B1 (en)	2008-01-09
CZ287198A3 (cs)	1999-02-17
DK1114819T3 (da)	2008-04-14
CA2248143A1 (en)	1997-10-16
CZ200788A3 (cs)	2017-01-25
ES2298198T3 (es)	2008-05-16
NO20015253D0 (no)	2001-10-26
CZ298060B6 (cs)	2007-06-06
CN1215393A (zh)	1999-04-28
ATE383347T1 (de)	2008-01-15
DK0892792T3 (da)	2002-04-02
WO1997037980A1 (en)	1997-10-16
NZ332278A (en)	2000-05-26
CN1496983A (zh)	2004-05-19
PT892792E (pt)	2002-05-31
HU0500044D0 (en)	2005-03-29
NO984737D0 (no)	1998-10-09
JP2000508312A (ja)	2000-07-04
PL192691B1 (pl)	2006-11-30
SK284703B6 (sk)	2005-09-08
CA2248143C (en)	2008-10-07
DE69738457D1 (de)	2008-02-21
PT1114819E (pt)	2008-02-28
DE69709718T2 (de)	2002-06-20
DE69709718D1 (de)	2002-02-21
RU2176643C2 (ru)	2001-12-10
AU2318297A (en)	1997-10-29
HK1018785A1 (en)	2000-01-07
HUP0500044A3 (en)	2005-09-28
JP2008239621A (ja)	2008-10-09
PL329295A1 (en)	1999-03-15
NO311837B1 (no)	2002-02-04
ATE209193T1 (de)	2001-12-15
EP0892792A1 (en)	1999-01-27
SG85683A1 (en)	2002-01-15
KR100530297B1 (ko)	2005-11-22
KR20040066189A (ko)	2004-07-23
AU706117B2 (en)	1999-06-10
NO984737L (no)	1998-12-09
CN1082953C (zh)	2002-04-17

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