SE9402490D0 - Vitronection binding protein - Google Patents

Vitronection binding protein

Info

Publication number
SE9402490D0
SE9402490D0 SE9402490A SE9402490A SE9402490D0 SE 9402490 D0 SE9402490 D0 SE 9402490D0 SE 9402490 A SE9402490 A SE 9402490A SE 9402490 A SE9402490 A SE 9402490A SE 9402490 D0 SE9402490 D0 SE 9402490D0
Authority
SE
Sweden
Prior art keywords
protein
vitronectin
binding protein
vitronection
concerns
Prior art date
Application number
SE9402490A
Other languages
Swedish (sv)
Inventor
Jan-Ingmar Flock
Torkel Wadstroem
Olin Liang
Original Assignee
Jan Ingmar Flock
Torkel Wadstroem
Olin Liang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jan Ingmar Flock, Torkel Wadstroem, Olin Liang filed Critical Jan Ingmar Flock
Priority to SE9402490A priority Critical patent/SE9402490D0/en
Publication of SE9402490D0 publication Critical patent/SE9402490D0/en
Priority to EP95926088A priority patent/EP0776336A1/en
Priority to JP8504958A priority patent/JPH10505581A/en
Priority to PCT/SE1995/000861 priority patent/WO1996002566A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56944—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention concerns a new vitronectin binding protein from Streptococcus aureus. The protein is involved in the infectious process of the microorganism. The invention also concerns a method for preparation thereof and a quinquedecapeptide with the amino acid sequence AKKQRFRHRNRKGYR, that is useful for preparing the protein and blocking the protein binding site to vitronectin. Further the invention relates to an antibody against the protein, pharmaceutical compositions and a diagnostic or analytical kit comprising said protein, peptide or antibody and a vaccine. Finally, the invention concerns a method for purifying vitronectin by using the vitronectin binding protein in an affinity column.
SE9402490A 1994-07-15 1994-07-15 Vitronection binding protein SE9402490D0 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
SE9402490A SE9402490D0 (en) 1994-07-15 1994-07-15 Vitronection binding protein
EP95926088A EP0776336A1 (en) 1994-07-15 1995-07-14 Vitronectin binding protein
JP8504958A JPH10505581A (en) 1994-07-15 1995-07-14 Vitronectin binding protein
PCT/SE1995/000861 WO1996002566A1 (en) 1994-07-15 1995-07-14 Vitronectin binding protein

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9402490A SE9402490D0 (en) 1994-07-15 1994-07-15 Vitronection binding protein

Publications (1)

Publication Number Publication Date
SE9402490D0 true SE9402490D0 (en) 1994-07-15

Family

ID=20394737

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9402490A SE9402490D0 (en) 1994-07-15 1994-07-15 Vitronection binding protein

Country Status (4)

Country Link
EP (1) EP0776336A1 (en)
JP (1) JPH10505581A (en)
SE (1) SE9402490D0 (en)
WO (1) WO1996002566A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6680195B1 (en) * 1997-11-26 2004-01-20 Inhibitex, Inc. Extracellular matrix-binding proteins from staphylococcus aureus
EP1125507A1 (en) * 2000-02-15 2001-08-22 Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.) Inulin products with improved nutritional properties
SE0000514D0 (en) * 2000-02-17 2000-02-17 Biostapro Ab A 52 kDa protein from coagulase negative staphylococci and fragments

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0621875B1 (en) * 1992-09-21 2002-03-27 Alfa-Laval Agri International Ab Fibrinogen binding protein
NZ261149A (en) * 1993-02-05 1997-07-27 Smithkline Beecham Plc Staphylococcus aureus polypeptides and monoclonal antibodies therefrom, their production and use

Also Published As

Publication number Publication date
JPH10505581A (en) 1998-06-02
WO1996002566A1 (en) 1996-02-01
EP0776336A1 (en) 1997-06-04

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