PT973769E - Processo para a preparacao de eprosartan - Google Patents

Processo para a preparacao de eprosartan

Info

Publication number: PT973769E
Authority: PT; Portugal
Prior art keywords: eprosartan; preparation
Prior art date: 1997-02-14

Application number

PT98904999T

Other languages

English (en)

Inventor

Richard T Matsuoka

Peng Liu

Original Assignee

Smithkline Beckman Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-02-14

Filing date

1998-02-13

Publication date

2004-11-30

1998-02-13 Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp

2004-11-30 Publication of PT973769E publication Critical patent/PT973769E/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PT98904999T 1997-02-14 1998-02-13 Processo para a preparacao de eprosartan PT973769E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US3819697P	1997-02-14	1997-02-14

Publications (1)

Publication Number	Publication Date
PT973769E true PT973769E (pt)	2004-11-30

Family

ID=21898590

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT98904999T PT973769E (pt)	1997-02-14	1998-02-13	Processo para a preparacao de eprosartan

Country Status (41)

Country	Link
US (2)	US6294675B1 (pt)
EP (1)	EP0973769B1 (pt)
JP (1)	JP4227671B2 (pt)
KR (1)	KR100551667B1 (pt)
CN (1)	CN1093128C (pt)
AP (1)	AP1202A (pt)
AR (1)	AR011126A1 (pt)
AT (1)	ATE274511T1 (pt)
AU (1)	AU730162B2 (pt)
BG (1)	BG63970B1 (pt)
BR (1)	BRPI9808642B8 (pt)
CA (1)	CA2281471C (pt)
CO (1)	CO4950549A1 (pt)
CY (1)	CY2551B1 (pt)
CZ (1)	CZ296543B6 (pt)
DE (1)	DE69825880T2 (pt)
DK (1)	DK0973769T3 (pt)
DZ (1)	DZ2418A1 (pt)
EA (1)	EA001761B1 (pt)
EG (1)	EG23780A (pt)
ES (1)	ES2224358T3 (pt)
HK (1)	HK1026206A1 (pt)
HU (1)	HU228098B1 (pt)
ID (1)	ID23155A (pt)
IL (4)	IL143784A (pt)
IN (1)	IN188000B (pt)
MA (1)	MA24472A1 (pt)
MY (1)	MY120024A (pt)
NO (1)	NO317761B1 (pt)
NZ (1)	NZ337182A (pt)
OA (1)	OA11086A (pt)
PE (1)	PE59799A1 (pt)
PL (1)	PL192837B1 (pt)
PT (1)	PT973769E (pt)
SA (1)	SA98190146B1 (pt)
SI (1)	SI0973769T1 (pt)
SK (1)	SK285125B6 (pt)
TR (1)	TR199901935T2 (pt)
UA (1)	UA57060C2 (pt)
WO (1)	WO1998035962A1 (pt)
ZA (1)	ZA981208B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR011126A1 (es) *	1997-02-14	2000-08-02	Smithkline Beecham Corp	Procedimiento para preparar eprosartano y compuestos intermediarios.
US6630498B2 (en) *	1997-08-06	2003-10-07	Smithkline Beecham Corporation	Eprosartan arginyl charge-neutralization-complex and a process for its preparation and formulation
EP1098634A4 (en) *	1998-07-20	2006-10-25	Smithkline Beecham Corp	EPROSARTAN CONTAINING MORE EFFECTIVE FORMULATIONS IN ORAL SOLID PHARMACEUTICAL FORM
US20060099230A1 (en) *	2004-11-10	2006-05-11	Chin-Chih Chiang	Novel formulations of eprosartan with enhanced bioavailability
US20100137613A1 (en) *	2006-12-27	2010-06-03	Hetero Drugs Limited	Process for eprosartan
AU2008315651B2 (en) *	2007-10-22	2012-12-13	Orchid Research Laboratories Limited	Histone deacetylase inhibitors
CN101215284B (zh) *	2007-12-31	2010-10-13	浙江华海药业股份有限公司	一种改进的依普罗沙坦的制备方法
WO2011004384A2 (en)	2009-06-05	2011-01-13	Glochem Industries Limited	Process for the preparation of eprosartan
CN102584709B (zh) *	2011-12-19	2016-08-17	浙江华海药业股份有限公司	一种改进的依普罗沙坦中间体芳基咪唑醛的制备工艺
CN103288742A (zh) *	2013-06-04	2013-09-11	四川百利药业有限责任公司	一种高纯度英加韦林原料的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5185351A (en) *	1989-06-14	1993-02-09	Smithkline Beecham Corporation	Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
US5418250A (en) *	1989-06-14	1995-05-23	Smithkline Beecham Corporation	Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
ES2142789T3 (es)	1989-06-14	2000-05-01	Smithkline Beecham Corp	Acidos imidazolil-alquenoicos.
NZ239161A (en) *	1990-07-31	1994-01-26	Smithkline Beecham Corp	Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
AU9137791A (en)	1990-12-14	1992-07-08	Smithkline Beecham Corporation	Imidazolyl-alkenoic acids
AR011126A1 (es) *	1997-02-14	2000-08-02	Smithkline Beecham Corp	Procedimiento para preparar eprosartano y compuestos intermediarios.

1998
- 1998-02-10 AR ARP980100586A patent/AR011126A1/es active IP Right Grant
- 1998-02-11 DZ DZ980028A patent/DZ2418A1/xx active
- 1998-02-11 MY MYPI98000545A patent/MY120024A/en unknown
- 1998-02-11 EG EG15498A patent/EG23780A/xx active
- 1998-02-12 PE PE1998000102A patent/PE59799A1/es not_active IP Right Cessation
- 1998-02-12 IN IN361DE1998 patent/IN188000B/en unknown
- 1998-02-12 MA MA24963A patent/MA24472A1/fr unknown
- 1998-02-13 PL PL335074A patent/PL192837B1/pl unknown
- 1998-02-13 IL IL14378498A patent/IL143784A/xx not_active IP Right Cessation
- 1998-02-13 DK DK98904999T patent/DK0973769T3/da active
- 1998-02-13 IL IL14378598A patent/IL143785A/en not_active IP Right Cessation
- 1998-02-13 SI SI9830688T patent/SI0973769T1/xx unknown
- 1998-02-13 ZA ZA981208A patent/ZA981208B/xx unknown
- 1998-02-13 SK SK1086-99A patent/SK285125B6/sk not_active IP Right Cessation
- 1998-02-13 DE DE69825880T patent/DE69825880T2/de not_active Expired - Lifetime
- 1998-02-13 CN CN98802483A patent/CN1093128C/zh not_active Expired - Lifetime
- 1998-02-13 NZ NZ337182A patent/NZ337182A/en not_active IP Right Cessation
- 1998-02-13 AU AU62732/98A patent/AU730162B2/en not_active Expired
- 1998-02-13 EA EA199900741A patent/EA001761B1/ru not_active IP Right Cessation
- 1998-02-13 CZ CZ0285199A patent/CZ296543B6/cs not_active IP Right Cessation
- 1998-02-13 AP APAP/P/1999/001619A patent/AP1202A/en active
- 1998-02-13 PT PT98904999T patent/PT973769E/pt unknown
- 1998-02-13 ID IDW990840Q patent/ID23155A/id unknown
- 1998-02-13 IL IL14378398A patent/IL143783A/xx not_active IP Right Cessation
- 1998-02-13 TR TR1999/01935T patent/TR199901935T2/xx unknown
- 1998-02-13 IL IL13131098A patent/IL131310A/xx not_active IP Right Cessation
- 1998-02-13 BR BRPI9808642A patent/BRPI9808642B8/pt not_active IP Right Cessation
- 1998-02-13 ES ES98904999T patent/ES2224358T3/es not_active Expired - Lifetime
- 1998-02-13 AT AT98904999T patent/ATE274511T1/de active
- 1998-02-13 WO PCT/US1998/002411 patent/WO1998035962A1/en active IP Right Grant
- 1998-02-13 US US09/355,186 patent/US6294675B1/en not_active Expired - Lifetime
- 1998-02-13 HU HU0001813A patent/HU228098B1/hu unknown
- 1998-02-13 KR KR1019997007274A patent/KR100551667B1/ko not_active IP Right Cessation
- 1998-02-13 CA CA002281471A patent/CA2281471C/en not_active Expired - Lifetime
- 1998-02-13 JP JP53584098A patent/JP4227671B2/ja not_active Expired - Lifetime
- 1998-02-13 EP EP98904999A patent/EP0973769B1/en not_active Expired - Lifetime
- 1998-02-13 UA UA99084525A patent/UA57060C2/uk unknown
- 1998-02-13 CO CO98007696A patent/CO4950549A1/es unknown
- 1998-06-14 SA SA98190146A patent/SA98190146B1/ar unknown
1999
- 1999-08-10 BG BG103649A patent/BG63970B1/bg unknown
- 1999-08-13 NO NO993912A patent/NO317761B1/no not_active IP Right Cessation
- 1999-08-13 OA OA9900180A patent/OA11086A/en unknown
2000
- 2000-07-25 HK HK00104616A patent/HK1026206A1/xx not_active IP Right Cessation
2001
- 2001-08-14 US US09/929,604 patent/US6458963B1/en not_active Expired - Fee Related
2006
- 2006-02-14 CY CY0600005A patent/CY2551B1/xx unknown

Also Published As

Publication number	Publication date
NZ337182A (en)	2001-04-27
JP2001511808A (ja)	2001-08-14
BG103649A (en)	2000-06-30
IN188000B (pt)	2002-08-03
BR9808642A (pt)	2000-05-23
DK0973769T3 (da)	2004-12-13
IL143783A (en)	2005-05-17
US6294675B1 (en)	2001-09-25
EP0973769A1 (en)	2000-01-26
CN1247538A (zh)	2000-03-15
CO4950549A1 (es)	2000-09-01
IL143785A0 (en)	2002-04-21
EA199900741A1 (ru)	2000-02-28
IL131310A0 (en)	2001-01-28
WO1998035962A1 (en)	1998-08-20
PL335074A1 (en)	2000-04-10
HUP0001813A2 (hu)	2001-06-28
OA11086A (en)	2003-03-13
CA2281471C (en)	2007-04-24
CN1093128C (zh)	2002-10-23
AU6273298A (en)	1998-09-08
IL143784A0 (en)	2002-04-21
DZ2418A1 (fr)	2003-06-26
IL143783A0 (en)	2002-04-21
SK285125B6 (sk)	2006-06-01
BRPI9808642B8 (pt)	2021-05-25
KR20000071008A (ko)	2000-11-25
UA57060C2 (uk)	2003-06-16
ES2224358T3 (es)	2005-03-01
EP0973769A4 (en)	2001-01-24
CA2281471A1 (en)	1998-08-20
NO993912D0 (no)	1999-08-13
TR199901935T2 (xx)	1999-12-21
AR011126A1 (es)	2000-08-02
CZ285199A3 (cs)	2000-02-16
EA001761B1 (ru)	2001-08-27
AP9901619A0 (en)	1999-09-30
US6458963B1 (en)	2002-10-01
AU730162B2 (en)	2001-03-01
CZ296543B6 (cs)	2006-04-12
CY2551B1 (en)	2008-07-02
ATE274511T1 (de)	2004-09-15
ZA981208B (en)	1998-11-12
EP0973769B1 (en)	2004-08-25
PE59799A1 (es)	1999-08-06
SK108699A3 (en)	2000-05-16
US20020028951A1 (en)	2002-03-07
SA98190146B1 (ar)	2006-08-20
IL143784A (en)	2005-05-17
HU228098B1 (en)	2012-10-29
IL143785A (en)	2004-12-15
MY120024A (en)	2005-08-30
HUP0001813A3 (en)	2001-07-30
ID23155A (id)	2000-03-23
BR9808642B1 (pt)	2013-11-26
HK1026206A1 (en)	2000-12-08
MA24472A1 (fr)	1998-10-01
KR100551667B1 (ko)	2006-02-13
AP1202A (en)	2003-09-02
EG23780A (en)	2007-08-13
DE69825880T2 (de)	2005-09-08
PL192837B1 (pl)	2006-12-29
JP4227671B2 (ja)	2009-02-18
BG63970B1 (bg)	2003-08-29
NO993912L (no)	1999-08-13
IL131310A (en)	2003-02-12
SI0973769T1 (en)	2004-12-31
DE69825880D1 (de)	2004-09-30
NO317761B1 (no)	2004-12-13

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BR9702047A (pt)	1998-01-13	Processo para a preparação de uréia granular
PT880498E (pt)	2002-05-31	Processo para a preparacao de compostos dicetonicos
BR9804873A (pt)	1999-08-24	Processo para a produ-Æo de ironas
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BR9612457A (pt)	1999-07-13	Processo para a fabricação de felodipina
BR9805538B1 (pt)	2009-05-05	processo para a preparação de ferro-succinilcaseìna.
PT1200414E (pt)	2005-09-30	Processo para a preparacao de pirimidnas substituidas