PT91631A - A process for the preparation of cyclic graf-analogs ii - Google Patents

A process for the preparation of cyclic graf-analogs ii

Info

Publication number
PT91631A
PT91631A PT91631A PT9163189A PT91631A PT 91631 A PT91631 A PT 91631A PT 91631 A PT91631 A PT 91631A PT 9163189 A PT9163189 A PT 9163189A PT 91631 A PT91631 A PT 91631A
Authority
PT
Portugal
Prior art keywords
graf
analogs
cyclic
preparation
cyclic graf
Prior art date
Application number
PT91631A
Other languages
English (en)
Other versions
PT91631B (pt
Inventor
Arthur Martin Felix
David Charles Fry
Edgar Philip Heimer
Vincent Stewart Madison
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT91631A publication Critical patent/PT91631A/pt
Publication of PT91631B publication Critical patent/PT91631B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PT91631A 1988-09-06 1989-09-05 Processo para a preparacao de analogos de grf ciclicos PT91631B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/240,662 US5084442A (en) 1988-09-06 1988-09-06 Cyclic growth hormone releasing factor analogs and method for the manufacture thereof

Publications (2)

Publication Number Publication Date
PT91631A true PT91631A (pt) 1990-03-30
PT91631B PT91631B (pt) 1995-05-31

Family

ID=22907441

Family Applications (1)

Application Number Title Priority Date Filing Date
PT91631A PT91631B (pt) 1988-09-06 1989-09-05 Processo para a preparacao de analogos de grf ciclicos

Country Status (8)

Country Link
US (1) US5084442A (pt)
EP (1) EP0365779A3 (pt)
JP (1) JPH0291098A (pt)
AU (1) AU636301B2 (pt)
DK (1) DK437189A (pt)
NZ (1) NZ230549A (pt)
PT (1) PT91631B (pt)
ZA (1) ZA896767B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0542937A1 (en) * 1991-04-09 1993-05-26 F. Hoffmann-La Roche Ag Growth hormone releasing factor analogs
AU656230B2 (en) * 1991-10-11 1995-01-27 F. Hoffmann-La Roche Ag Cyclic vasoactive peptides
WO1993017701A1 (en) * 1992-03-12 1993-09-16 The Administrators Of The Tulane Educational Fund Endothelin receptor-binding peptides
US5620675A (en) * 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US5493006A (en) * 1993-06-16 1996-02-20 The Salk Institute For Biological Studies Cyclic CRF analogs
US6008058A (en) * 1993-06-18 1999-12-28 University Of Louisville Cyclic peptide mixtures via side chain or backbone attachment and solid phase synthesis
JPH10506091A (ja) * 1993-11-09 1998-06-16 メルク エンド カンパニー インコーポレーテッド 成長ホルモン放出促進性のピペリジン、ピロリジンおよびヘキサヒドロ−１ｈ−アゼピン類
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
US5942489A (en) * 1996-05-03 1999-08-24 The Administrators Of The Tulane Educational Fund HGH-RH(1-29)NH2 analogues having antagonistic activity
US5734012A (en) * 1996-05-16 1998-03-31 Ohmeda Pharmaceutical Products Division Inc. Cyclic motilin-like polypeptides with gastrointestinal motor stimulating activity
EP1204321B1 (en) * 1999-07-26 2005-11-09 Baylor College Of Medicine Super-active porcine growth hormone releasing hormone analog
US20040192593A1 (en) 1999-07-26 2004-09-30 Baylor College Of Medicine Protease resistant ti-growth hormone releasing hormone
US7338656B2 (en) 2001-10-26 2008-03-04 Baylor College Of Medicine Composition and method to alter lean body mass and bone properties in a subject
MY142457A (en) 2001-12-11 2010-11-30 Advisys Inc Plasmid mediated supplementation for treating chronically ill subjects
WO2003066825A2 (en) * 2002-02-07 2003-08-14 Baylor College Of Medicine Modified pituitary gland development in offspring from expectant mother animals treated with growth hormone releasing hormone therapy
US20040204358A1 (en) * 2003-01-28 2004-10-14 Advisys, Inc. Reducing culling in herd animals growth hormone releasing hormone (GHRH)
TW200424214A (en) * 2003-04-21 2004-11-16 Advisys Inc Plasmid mediated GHRH supplementation for renal failures
US7361642B2 (en) * 2003-08-04 2008-04-22 Vgx Pharmaceuticals, Inc. Canine specific growth hormone releasing hormone
US8188056B2 (en) * 2003-12-31 2012-05-29 Vgx Pharmaceuticals, Inc. Reducing arthritis and lameness in subjects by growth hormone releasing hormone (GHRH) supplementation
DE602005027661D1 (de) * 2004-01-20 2011-06-09 VGX Pharmaceuticals LLC Isetzendem hormon (ghrh) aus muskelzellen durch speziesspezifisches signalpeptid
CN101027081A (zh) * 2004-07-23 2007-08-29 阿德维希斯公司 生长激素释放激素增强疫苗接种应答
US8058253B2 (en) * 2006-07-06 2011-11-15 Vgx Pharmaceuticals, Inc. Growth hormone releasing hormone treatment to decrease cholesterol levels
RU2748576C2 (ru) 2016-04-19 2021-05-27 Гриффон Фармасьютикалз Интернешнл Са. Пэгилированные биологически активные пептиды и их применение

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649131A (en) * 1984-09-24 1987-03-10 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
CA1271600A (en) * 1985-01-07 1990-07-10 David Howard Coy Growth hormone-releasing peptides and method of treating mammals therewith
EP0193910A3 (en) * 1985-03-06 1988-11-23 Sumitomo Pharmaceuticals Company, Limited Synthesis of a derivative of grf and intermediate peptides
US4808701A (en) * 1987-03-30 1989-02-28 Hoffmann-La Roche Inc. Cyclic peptides having appetite regulating activity
US4959352A (en) * 1987-09-18 1990-09-25 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
EP0307860B1 (en) * 1987-09-18 1994-06-08 F. Hoffmann-La Roche Ag Cyclic GRF-analogs

Also Published As

Publication number Publication date
EP0365779A3 (en) 1990-07-11
EP0365779A2 (en) 1990-05-02
DK437189D0 (da) 1989-09-04
PT91631B (pt) 1995-05-31
DK437189A (da) 1990-03-07
AU4109689A (en) 1990-03-15
JPH0291098A (ja) 1990-03-30
US5084442A (en) 1992-01-28
ZA896767B (en) 1990-06-27
NZ230549A (en) 1993-03-26
AU636301B2 (en) 1993-04-29

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19941109

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20010531