PA8601501A1 - PROCESS - Google Patents

PROCESS

Info

Publication number
PA8601501A1
PA8601501A1 PA20048601501A PA8601501A PA8601501A1 PA 8601501 A1 PA8601501 A1 PA 8601501A1 PA 20048601501 A PA20048601501 A PA 20048601501A PA 8601501 A PA8601501 A PA 8601501A PA 8601501 A1 PA8601501 A1 PA 8601501A1
Authority
PA
Panama
Prior art keywords
amlodipine
pulified
monohidrate
mesilate
anhydro
Prior art date
Application number
PA20048601501A
Other languages
Spanish (es)
Inventor
Narayanrao Kankan Rajendra
Ramachandra Rao Dharmaraj
Pathi L Srinivas
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0309471A external-priority patent/GB0309471D0/en
Priority claimed from GB0314617A external-priority patent/GB0314617D0/en
Application filed by Cipla Ltd filed Critical Cipla Ltd
Publication of PA8601501A1 publication Critical patent/PA8601501A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

MONOHIDRATO DE MESILATO DE AMLODIPINA ES PREPARADO YA SEA A PARTIR DE MESILATO DE AMLODIPINA ANHIDRO, O EN LA PRESENCIA DE UN MEDIO SOLVENTE DE AGUA INMISCIBLE A PARTIR DE AMLODIPINA PURIFICADA Y ACIDO SULFONICO DE METANO.AMLODIPINE MESYLATE MONOHIDRATE IS PREPARED EITHER FROM ANHYDRO AMLODIPINE MESILATE, OR IN THE PRESENCE OF A SOLVENT MEDIUM OF WATER IMMISCIBLE FROM PULIFIED AMLODIPINE AND SULPHONIC ACID OF METHANE.

PA20048601501A 2003-04-25 2004-04-23 PROCESS PA8601501A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0309471A GB0309471D0 (en) 2003-04-25 2003-04-25 Process
GB0314617A GB0314617D0 (en) 2003-06-23 2003-06-23 Process

Publications (1)

Publication Number Publication Date
PA8601501A1 true PA8601501A1 (en) 2004-12-16

Family

ID=33420880

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20048601501A PA8601501A1 (en) 2003-04-25 2004-04-23 PROCESS

Country Status (6)

Country Link
AR (1) AR044063A1 (en)
CL (1) CL2004000864A1 (en)
DE (1) DE112004000712T5 (en)
GB (1) GB2415696B (en)
PA (1) PA8601501A1 (en)
WO (1) WO2004096770A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1152013C (en) * 2001-11-22 2004-06-02 张喜田 Levo-amlodipine salt able to generate hydrate and its hydrate and preparation
WO2021114012A1 (en) * 2019-12-09 2021-06-17 昆明赛诺制药股份有限公司 Amlodipine mesylate monohydrate, preparation method therefor and use thereof
CN112538044B (en) * 2019-12-09 2021-08-13 昆明赛诺制药股份有限公司 Amlodipine mesylate monohydrate, and preparation method and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161312C (en) * 1982-03-11 1991-12-09 Pfizer CHANGES FOR THE PREPARATION FOR THE PREPARATION OF 2-Amino-CO-Methyl-4-Methyl-4-Methyl-4-Methyl-4-Methyl-4-Methyl-4-Methyl-2-D-Hydroxy
GB8608335D0 (en) * 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts
DE50112189D1 (en) * 2001-01-09 2007-04-26 Siegfried Generics Int Ag Salts of amlodipine mesylate

Also Published As

Publication number Publication date
GB2415696B (en) 2007-06-20
GB2415696A (en) 2006-01-04
DE112004000712T5 (en) 2006-10-19
GB0522075D0 (en) 2005-12-07
WO2004096770A1 (en) 2004-11-11
CL2004000864A1 (en) 2005-04-22
AR044063A1 (en) 2005-08-24

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