OA07674A - Procédé de préparation de dérivés de carbapénem, nouveaux intermédiaires de synthèse et préparation de ces intermédiaires. - Google Patents

Procédé de préparation de dérivés de carbapénem, nouveaux intermédiaires de synthèse et préparation de ces intermédiaires.

Info

Publication number: OA07674A
Authority: OA; OAPI
Prior art keywords: preparation; intermediates; new synthetic; carbapenem derivatives; synthetic intermediates
Prior art date: 1983-03-08

Application number

OA58247A

Other languages

English (en)

Inventor

Dextraze Pierre

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-03-08

Filing date

1984-03-07

Publication date

1985-05-23

1984-03-07 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1985-05-23 Publication of OA07674A publication Critical patent/OA07674A/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

OA58247A 1983-03-08 1984-03-07 Procédé de préparation de dérivés de carbapénem, nouveaux intermédiaires de synthèse et préparation de ces intermédiaires. OA07674A (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US47137883A	1983-03-08	1983-03-08
US49969183A	1983-06-07	1983-06-07
US55729583A	1983-12-01	1983-12-01

Publications (1)

Publication Number	Publication Date
OA07674A true OA07674A (fr)	1985-05-23

Family

ID=27413179

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA58247A OA07674A (fr)	1983-03-08	1984-03-07	Procédé de préparation de dérivés de carbapénem, nouveaux intermédiaires de synthèse et préparation de ces intermédiaires.

Country Status (31)

Country	Link
JP (1)	JPH05255250A (fr)
KR (1)	KR900002247B1 (fr)
AR (1)	AR241016A1 (fr)
AT (1)	AT387968B (fr)
AU (2)	AU572124B2 (fr)
CA (1)	CA1284324C (fr)
CH (1)	CH658248A5 (fr)
CY (1)	CY1546A (fr)
DD (1)	DD228258A5 (fr)
DE (1)	DE3408347A1 (fr)
DK (1)	DK140584A (fr)
ES (2)	ES530337A0 (fr)
FI (1)	FI840863A (fr)
FR (1)	FR2542316B1 (fr)
GB (1)	GB2136802B (fr)
GR (1)	GR81871B (fr)
HK (1)	HK82990A (fr)
HU (1)	HU193895B (fr)
IE (1)	IE57098B1 (fr)
IL (1)	IL71149A (fr)
IT (1)	IT1178465B (fr)
LU (1)	LU85241A1 (fr)
NL (1)	NL8400702A (fr)
NO (1)	NO166038C (fr)
NZ (1)	NZ207346A (fr)
OA (1)	OA07674A (fr)
PT (1)	PT78211B (fr)
SE (2)	SE8401278L (fr)
SG (1)	SG35490G (fr)
YU (2)	YU46147B (fr)
ZW (1)	ZW3884A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4683301A (en) *	1982-04-08	1987-07-28	Bristol-Myers Company	Carbapenem antibiotics
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
CA1285940C (fr) *	1984-07-02	1991-07-09	Merck & Co., Inc.	Carbapenems a substituant heteroarylalkylthio, quaternise en 2
IE851586L (en) *	1984-07-02	1986-01-02	Interchem Internat S A	I methylcarbapenems having a 2-quaternary¹heteroarylalkylthio substituent
US4665169A (en) *	1985-09-11	1987-05-12	Bristol-Myers Company	Carbapenem antibiotics
US4880922A (en) *	1985-11-22	1989-11-14	Bristol-Myers Company	Carbapenems with quaternized heterothioalkylthio substitution at position 2
NZ219892A (en) *	1986-04-15	1991-02-26	Merck & Co Inc	N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof
IE910606A1 (en) *	1990-02-23	1991-08-28	Sankyo Co	Carbapenem derivatives having antibiotic activity, their¹preparation and their use
US5712267A (en) *	1991-06-04	1998-01-27	Sankyo Company,. Limited	Carbapenem derivatives, their preparation and their use as antibiotics
PL1631557T3 (pl)	2003-06-12	2007-05-31	Btg Int Ltd	Cykliczne hydroksyloaminy jako związki psychoaktywne
FR2921258A1 (fr) *	2007-09-24	2009-03-27	Oreal	Composition tinctoriale comprenant au moins un precurseur incolore disulfures/thiol, proced de coloration a partir de la composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55147284A (en) *	1979-04-17	1980-11-17	Sanraku Inc	Novel beta-lactam derivative and its preparation
IE52147B1 (en) *	1980-03-27	1987-07-08	Merck & Co Inc	4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0038869A1 (fr) *	1980-04-30	1981-11-04	Merck & Co. Inc.	Procédé de préparation de 1-carbapénèmes et intermédiaires pour leur préparation
EP0060612A1 (fr) *	1981-02-04	1982-09-22	Beecham Group Plc	Procédé pour la préparation de dérivés de l'azabicyclo-(3.2.0) heptène-2
US4552873A (en) *	1981-08-19	1985-11-12	Sankyo Company Limited	Carbapenem compounds, and compositions containing them
EP0074599A1 (fr) *	1981-09-09	1983-03-23	Takeda Chemical Industries, Ltd.	Dérivés de 5,6-cis-carbapénème, leurs préparation et utilisation
US4552696A (en) *	1982-04-09	1985-11-12	Bristol-Myers Company	Carbapenem antibiotics
US4536335A (en) *	1982-06-18	1985-08-20	Bristol-Myers Company	Carbapenem antibiotics

1984
- 1984-02-29 AR AR295877A patent/AR241016A1/es active
- 1984-02-29 DK DK140584A patent/DK140584A/da not_active Application Discontinuation
- 1984-03-01 NZ NZ207346A patent/NZ207346A/en unknown
- 1984-03-05 IL IL71149A patent/IL71149A/xx unknown
- 1984-03-05 ZW ZW38/84A patent/ZW3884A1/xx unknown
- 1984-03-05 NL NL8400702A patent/NL8400702A/xx not_active Application Discontinuation
- 1984-03-05 FI FI840863A patent/FI840863A/fi not_active Application Discontinuation
- 1984-03-06 CA CA000448904A patent/CA1284324C/fr not_active Expired - Fee Related
- 1984-03-06 GR GR73999A patent/GR81871B/el unknown
- 1984-03-06 CH CH1103/84A patent/CH658248A5/de not_active IP Right Cessation
- 1984-03-07 SE SE8401278A patent/SE8401278L/xx not_active Application Discontinuation
- 1984-03-07 AU AU25360/84A patent/AU572124B2/en not_active Ceased
- 1984-03-07 ES ES530337A patent/ES530337A0/es active Granted
- 1984-03-07 IE IE549/84A patent/IE57098B1/en not_active IP Right Cessation
- 1984-03-07 FR FR8403553A patent/FR2542316B1/fr not_active Expired
- 1984-03-07 GB GB08405984A patent/GB2136802B/en not_active Expired
- 1984-03-07 PT PT78211A patent/PT78211B/pt unknown
- 1984-03-07 OA OA58247A patent/OA07674A/fr unknown
- 1984-03-07 NO NO840865A patent/NO166038C/no unknown
- 1984-03-07 IT IT19945/84A patent/IT1178465B/it active
- 1984-03-07 LU LU85241A patent/LU85241A1/fr unknown
- 1984-03-07 HU HU84911A patent/HU193895B/hu not_active IP Right Cessation
- 1984-03-07 DE DE19843408347 patent/DE3408347A1/de not_active Withdrawn
- 1984-03-07 AT AT0076984A patent/AT387968B/de not_active IP Right Cessation
- 1984-03-07 DD DD84260663A patent/DD228258A5/de not_active IP Right Cessation
- 1984-03-08 YU YU42084A patent/YU46147B/sh unknown
- 1984-03-08 KR KR1019840001243A patent/KR900002247B1/ko not_active IP Right Cessation
- 1984-11-02 ES ES537349A patent/ES8507145A1/es not_active Expired
1986
- 1986-03-28 YU YU49486A patent/YU46305B/sh unknown
1987
- 1987-07-20 AU AU75924/87A patent/AU605491B2/en not_active Ceased
1989
- 1989-04-03 SE SE8901162A patent/SE8901162L/xx not_active Application Discontinuation
1990
- 1990-05-19 SG SG35490A patent/SG35490G/en unknown
- 1990-10-11 HK HK829/90A patent/HK82990A/xx unknown
1991
- 1991-03-22 CY CY1546A patent/CY1546A/xx unknown
- 1991-09-27 JP JP3274949A patent/JPH05255250A/ja active Pending

Also Published As

Publication number	Publication date
JPH05255250A (ja)	1993-10-05
SE8901162D0 (sv)	1989-04-03
KR840008157A (ko)	1984-12-13
AT387968B (de)	1989-04-10
GB8405984D0 (en)	1984-04-11
AU572124B2 (en)	1988-05-05
GR81871B (fr)	1984-12-12
YU42084A (en)	1986-08-31
IT1178465B (it)	1987-09-09
AU7592487A (en)	1987-10-22
ES8505205A1 (es)	1985-05-16
ATA76984A (de)	1988-09-15
AU605491B2 (en)	1991-01-17
DK140584D0 (da)	1984-02-29
NO840865L (no)	1984-09-10
FI840863A0 (fi)	1984-03-05
LU85241A1 (fr)	1984-11-14
ZW3884A1 (en)	1984-10-10
SE8901162L (sv)	1989-04-03
CH658248A5 (de)	1986-10-31
AU2536084A (en)	1984-09-13
SE8401278D0 (sv)	1984-03-07
NL8400702A (nl)	1984-10-01
PT78211B (en)	1986-08-12
DD228258A5 (de)	1985-10-09
IE840549L (en)	1984-09-08
YU46147B (sh)	1993-05-28
IL71149A0 (en)	1984-06-29
ES537349A0 (es)	1985-08-16
YU49486A (en)	1987-12-31
YU46305B (sh)	1993-05-28
AR241016A1 (es)	1991-04-30
HU193895B (en)	1987-12-28
CY1546A (en)	1991-03-22
SE8401278L (sv)	1984-09-09
FI840863A (fi)	1984-09-09
HUT34980A (en)	1985-05-28
KR900002247B1 (ko)	1990-04-07
IE57098B1 (en)	1992-04-22
SG35490G (en)	1990-07-13
IL71149A (en)	1990-03-19
DK140584A (da)	1984-09-09
DE3408347A1 (de)	1984-09-13
NZ207346A (en)	1987-01-23
HK82990A (en)	1990-10-19
GB2136802B (en)	1987-05-20
ES530337A0 (es)	1985-05-16
FR2542316B1 (fr)	1988-10-07
FR2542316A1 (fr)	1984-09-14
IT8419945A0 (it)	1984-03-07
CA1284324C (fr)	1991-05-21
NO166038B (no)	1991-02-11
AR241016A2 (es)	1991-04-30
GB2136802A (en)	1984-09-26
NO166038C (no)	1991-05-22
ES8507145A1 (es)	1985-08-16
PT78211A (en)	1984-04-01

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RO91871A (fr)	1987-07-30	Procede pour la preparation des derives de 1,4-dihydro-4-oxonaphtiridine
OA08919A (fr)	1989-10-31	Procédé de production de dérivés substitués de tétraline, chromanes et composés apparentés.
DZ701A1 (fr)	2004-09-13	Nouveaux dérivés de la vinyl-6, furo-(3,4-c)-pyridine ainsi que leur procédé de préparation.
ES540080A0 (es)	1986-05-16	Procedimiento de preparar nuevos derivados de 1,3-dihidro-6-(1-hidroxi-2-dimetilaminometil-alil)-7-hidroxi-furo-(3,4-c)-piridina
DZ702A1 (fr)	2004-09-13	Nouveaux dérivés de la carboxymethoxy-7 furo-(3,4-c)-pyridine ainsi que leur procédé de préparation.
OA06563A (fr)	1981-07-31	Procédé de préparation de nouveaux dérivés d'indolizine.
DZ1618A1 (fr)	2002-02-17	Procédé de préparation de distilmats moyens.
OA07674A (fr)	1985-05-23	Procédé de préparation de dérivés de carbapénem, nouveaux intermédiaires de synthèse et préparation de ces intermédiaires.
OA08235A (fr)	1987-10-30	Composés intermediaires de carbapénem et leur procédé de préparation.
OA06951A (fr)	1983-07-31	Dérivés de la thiéno-pyridinone, leur procédé de préparation et leur application thérapeutique.
OA07984A (fr)	1987-01-31	Procédé stéréocontrolé de préparation d'acetoxyazetidione.
FR2695645B1 (fr)	1994-12-16	Procédé de préparation de polyaminoborazines.
OA07833A (fr)	1986-11-20	Procédé de préparation de nouveaux dérivés de 1-(acétylamino)-2-amino-propanone.
OA06274A (fr)	1981-06-30	Procédé de préparation de nouveaux composés de type muramyl-péptide.
DZ687A1 (fr)	2004-09-13	Dérivés de la chlori-4-furo-(3,4-c)-pyridine et leur procédé de préparation.
MA21499A1 (fr)	1989-10-01	Procede de preparation de nouveaux derives de la i-arylsylfonyl 2-pyrrolidinone.
OA06451A (fr)	1981-07-31	Procédé de préparation de composés B-lactame.
OA06879A (fr)	1983-02-28	Procédé de préparation de dérivés d'hétéroprostaglandines.