NL7709998A - Foetal canine lung diploid cell line - for virus cultures esp. for rabies vaccine prodn. - Google Patents
Foetal canine lung diploid cell line - for virus cultures esp. for rabies vaccine prodn.Info
- Publication number
- NL7709998A NL7709998A NL7709998A NL7709998A NL7709998A NL 7709998 A NL7709998 A NL 7709998A NL 7709998 A NL7709998 A NL 7709998A NL 7709998 A NL7709998 A NL 7709998A NL 7709998 A NL7709998 A NL 7709998A
- Authority
- NL
- Netherlands
- Prior art keywords
- prodn
- cell line
- foetal
- esp
- virus
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title abstract 4
- 210000001840 diploid cell Anatomy 0.000 title abstract 2
- 241000282465 Canis Species 0.000 title 1
- 210000004072 lung Anatomy 0.000 title 1
- 229960003127 rabies vaccine Drugs 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 208000000655 Distemper Diseases 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 208000002606 Paramyxoviridae Infections Diseases 0.000 abstract 1
- 241000711798 Rabies lyssavirus Species 0.000 abstract 1
- 208000003836 bluetongue Diseases 0.000 abstract 1
- 208000014058 canine distemper Diseases 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 239000012909 foetal bovine serum Substances 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 208000005562 infectious bovine rhinotracheitis Diseases 0.000 abstract 1
- 210000005265 lung cell Anatomy 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- 231100001222 nononcogenic Toxicity 0.000 abstract 1
- 231100001221 nontumorigenic Toxicity 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16651—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18311—Metapneumovirus, e.g. avian pneumovirus
- C12N2760/18351—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18451—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18651—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20151—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A novel cell culture system suitable for virus prodn. comprises diploid cells from a foetal carine lung cell line in a nutrient culture medium. The medium pref. also contains foetal bovine serum, pref. at 10-20%. For vaccine prodn. esp. using infectious bovine rhinotracheitis, canine distemper, parainfluenza type 3, blue tongue or partic. rabies virus. The cell line is stable, viable and cheap. It can be subjected to culture and subcultures for up to 35 passages without change of characteristics. The cells are free from bacteria, fungi and accidental viruses, are non-tumorigenic and non-oncogenic, and give very high virus titres.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7709998A NL7709998A (en) | 1977-09-12 | 1977-09-12 | Foetal canine lung diploid cell line - for virus cultures esp. for rabies vaccine prodn. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL7709998A NL7709998A (en) | 1977-09-12 | 1977-09-12 | Foetal canine lung diploid cell line - for virus cultures esp. for rabies vaccine prodn. |
Publications (1)
Publication Number | Publication Date |
---|---|
NL7709998A true NL7709998A (en) | 1979-03-14 |
Family
ID=19829170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7709998A NL7709998A (en) | 1977-09-12 | 1977-09-12 | Foetal canine lung diploid cell line - for virus cultures esp. for rabies vaccine prodn. |
Country Status (1)
Country | Link |
---|---|
NL (1) | NL7709998A (en) |
-
1977
- 1977-09-12 NL NL7709998A patent/NL7709998A/en not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BV | The patent application has lapsed |