MXPA04006039A - Methods for the treatment of peripheral neural and vascular ailments. - Google Patents
Methods for the treatment of peripheral neural and vascular ailments.Info
- Publication number
- MXPA04006039A MXPA04006039A MXPA04006039A MXPA04006039A MXPA04006039A MX PA04006039 A MXPA04006039 A MX PA04006039A MX PA04006039 A MXPA04006039 A MX PA04006039A MX PA04006039 A MXPA04006039 A MX PA04006039A MX PA04006039 A MXPA04006039 A MX PA04006039A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- methods
- ailments
- compositions
- peripheral neural
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
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- A—HUMAN NECESSITIES
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61P17/16—Emollients or protectives, e.g. against radiation
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- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Alternative & Traditional Medicine (AREA)
- Obesity (AREA)
- Hematology (AREA)
Abstract
Compositions and methods for the treatment of peripheral neuraland vascular ailments are disclosed. The method comprises administering a flavonoid compound with antioxidant properties, optionally formulated in a pharmaceutically acceptable carrier. This compound or combination of compounds provides significant, effective relief of the symptoms of peripheral neural or vascular ailments. In addition, the compositions, when used according to the methods of the present invention, do not exhibit the severe side effects of many prior art compositions proposed for treatment of these ailments.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2001/049297 WO2002049575A2 (en) | 2000-12-21 | 2001-12-19 | Method and composition for the treatment of diabetic neuropathy |
PCT/US2002/035654 WO2003053336A2 (en) | 2001-12-19 | 2002-11-06 | Methods for the treatment of peripheral neural and vascular ailments |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA04006039A true MXPA04006039A (en) | 2004-09-27 |
Family
ID=21743140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA04006039A MXPA04006039A (en) | 2001-12-19 | 2002-11-06 | Methods for the treatment of peripheral neural and vascular ailments. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1455778A4 (en) |
JP (1) | JP2005518381A (en) |
CA (1) | CA2470603A1 (en) |
IL (1) | IL162505A0 (en) |
MX (1) | MXPA04006039A (en) |
NZ (1) | NZ533439A (en) |
WO (1) | WO2003053336A2 (en) |
ZA (1) | ZA200404614B (en) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
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JP5044122B2 (en) * | 2003-10-24 | 2012-10-10 | 株式会社明治 | Novel inhibitors of late glycation end product formation and aldose reductase inhibitors |
CA2543676C (en) * | 2003-10-30 | 2011-04-26 | Meiji Seika Kaisha, Ltd. | Tyrosinase activity inhibitor and ameliorant for facial blood flow |
WO2005046584A2 (en) * | 2003-11-05 | 2005-05-26 | Osteoscreen, Inc. | Stimulation of hair growth by ginkgo biloba flavanoids |
JP2006083105A (en) * | 2004-09-16 | 2006-03-30 | Ito En Ltd | Ameliorant for blood fluidity and food and beverage |
ZA200800266B (en) * | 2005-06-28 | 2009-08-26 | Kgk Synergize Inc | Compositions to improve the bioavailability of polymethoxyflavones and tocotrienols for the treatment of cardiovascular disease |
DE102005048777A1 (en) * | 2005-10-10 | 2007-04-12 | Beiersdorf Ag | Cosmetic formulations to improve the microcirculation of the skin |
DE102005048778A1 (en) * | 2005-10-10 | 2007-04-12 | Beiersdorf Ag | Cosmetic formulations to improve the appearance of the skin |
JP5132889B2 (en) * | 2006-02-27 | 2013-01-30 | 株式会社ポッカコーポレーション | Nerve growth factor potentiator |
WO2007117494A1 (en) * | 2006-04-05 | 2007-10-18 | Vertex Pharmaceuticals Incorporated | Deazapurines useful as inhibitors of janus kinases |
FR2904557B1 (en) * | 2006-08-01 | 2010-04-30 | Pf Medicament | NOVEL EUCALYPTUS EXTRACT, PREPARATION METHOD THEREOF AND THERAPEUTIC USES THEREOF |
GB0618168D0 (en) * | 2006-09-15 | 2006-10-25 | Babraham Inst | Compounds |
US20090060879A1 (en) * | 2007-09-04 | 2009-03-05 | The Procter & Gamble Company | Oral Compositions, Products and Methods Of Use |
KR20110033304A (en) * | 2008-07-23 | 2011-03-30 | 메사추세츠 인스티튜트 오브 테크놀로지 | Activation of histone deacetylase 1 (hdac1) protects against dna damage and increases neuronal survival |
JP5415216B2 (en) * | 2009-10-02 | 2014-02-12 | 日本メナード化粧品株式会社 | Topical skin preparation |
CN102266320B (en) * | 2010-07-20 | 2015-06-17 | 浙江养生堂天然药物研究所有限公司 | New application of hesperetin |
KR101021835B1 (en) | 2010-09-06 | 2011-03-17 | 충남대학교산학협력단 | A composition comprising chrysosplenol c for treating and preventing heart disease |
CN102151281B (en) * | 2011-01-24 | 2014-03-26 | 中国药科大学 | Flavonoid compound for preventing and treating diabetes and medicament application thereof |
EP3483150A1 (en) | 2011-07-22 | 2019-05-15 | Massachusetts Institute Of Technology | Activators of class 1 histone deacetylases (hdacs) and uses thereof |
NZ596015A (en) * | 2011-10-26 | 2014-04-30 | Anzamed Internat Ltd | Method and composition for the treatment of pain and/or inflammation |
CN102526248B (en) * | 2012-03-22 | 2013-07-17 | 赵海潞 | Traditional Chinese medicine prescription capable of curing diabetes wound fester and continuously reducing blood sugar |
US20180193306A1 (en) | 2012-03-23 | 2018-07-12 | Cardero Therapeutics, Inc. | Compounds and compositions for the treatment of muscular disorders and bone disorders |
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ITRM20120335A1 (en) * | 2012-07-13 | 2014-01-14 | Aboca Spa Societa Agricola | NEW COMPOSITIONS FOR NEUROPATHIC PAIN TREATMENT. |
WO2014095289A2 (en) * | 2012-12-20 | 2014-06-26 | Unilever Plc | Method of treating hair ageing |
US9844531B2 (en) | 2013-03-15 | 2017-12-19 | Abbott Laboratories | Methods of maintaining and improving muscle function |
CN104547872A (en) * | 2015-01-30 | 2015-04-29 | 山东省立医院 | Traditional Chinese medicine composition for treating epilepsy |
CN107126437A (en) * | 2016-02-29 | 2017-09-05 | 上海中医药大学 | A kind of medicinal usage of Sophoricoside |
KR101828379B1 (en) | 2016-03-30 | 2018-02-12 | 우석대학교 산학협력단 | Compositions for the improvement of memory and cognition ability, or prevention, delay, improvement or treatment of Alzheimer's disease comprising Rosa rugosa THUNB flower extracts or fractions |
KR101715294B1 (en) * | 2016-06-09 | 2017-03-10 | 연세대학교 산학협력단 | Composition having effects of skin moisturizing, exfoliating, improving skin elasticity, inhibiting erythema, anti-wrinkle or improving skin photoaging comprising diosmin or salt thereof |
WO2018078412A1 (en) * | 2016-10-31 | 2018-05-03 | Posi Visionary Solutions Llp | Topical microemulsion of diosmetin and uses thereof |
CN108164489B (en) * | 2018-03-20 | 2019-11-26 | 武汉轻工大学 | A kind of preparation method of Galangin |
BR102018005599A2 (en) * | 2018-03-21 | 2019-10-08 | Pedro Barboza Da Rocha | HAZARDOUS, HYDRATING, MOISTURIZING AND EMOLIENT COMPOSITION FOR TOPIC ADMINISTRATION IN INTERTRIGO SKIN INJURIES, SKIN INJURY AND FECAL INJURY AND OTHER RELATED INJURY. |
WO2020051644A1 (en) * | 2018-09-13 | 2020-03-19 | Norbio No. 2 Pty Ltd | Treatment of peripheral nervous tissue inflammation |
CN112014480B (en) * | 2019-05-28 | 2023-03-28 | 黄河科技学院 | Method for detecting content of effective components in Jiangzhining granules by UPLC-MS/MS |
WO2022157381A1 (en) * | 2021-01-25 | 2022-07-28 | Universiteit Hasselt | Phloretin for use in the treatment of neurodegenerative and demyelinating diseases |
CN115317497A (en) * | 2022-01-13 | 2022-11-11 | 宁夏医科大学 | Application of liquiritin in preparing thoracic aorta vasodilation medicine |
CN114392256B (en) * | 2022-02-22 | 2023-05-09 | 中山大学附属第八医院(深圳福田) | Application of cyanidin in preventing and treating vascular calcification |
WO2024112947A1 (en) * | 2022-11-23 | 2024-05-30 | Brightseed, Inc. | Compositions and methods for modulating sleep and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH03232851A (en) * | 1989-12-26 | 1991-10-16 | Nippon Flour Mills Co Ltd | Aldose reductase inhibitor |
JPH09235284A (en) * | 1995-02-23 | 1997-09-09 | Nissan Chem Ind Ltd | Indole-type thiazolidine compound |
IT1291113B1 (en) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | NUTRITIONAL THERAPEUTIC COMPOSITION FOR SUBJECTS WITH DIABETES MELLITUS |
IT1302307B1 (en) * | 1998-09-01 | 2000-09-05 | Sigma Tau Healthscience Spa | COMPOSITION WITH ANTIOXIDANT ACTIVITY AND FOR IMPROVING THE METABOLIC USE OF GLUCOSE, INCLUDING ACETYL |
JP4497566B2 (en) * | 1998-09-02 | 2010-07-07 | 株式会社 日本薬用食品研究所 | Aldose reductase inhibitors and novel saponins and novel sapogenols |
US20030203857A1 (en) * | 2000-04-11 | 2003-10-30 | Hiromu Ohnogi | Remedies |
EP1351679B1 (en) * | 2000-12-21 | 2010-02-03 | The Quigley Corporation | Method and composition for the treatment of diabetic neuropathy |
-
2002
- 2002-11-06 JP JP2003554096A patent/JP2005518381A/en active Pending
- 2002-11-06 EP EP02789474A patent/EP1455778A4/en not_active Withdrawn
- 2002-11-06 NZ NZ533439A patent/NZ533439A/en not_active IP Right Cessation
- 2002-11-06 CA CA002470603A patent/CA2470603A1/en not_active Abandoned
- 2002-11-06 WO PCT/US2002/035654 patent/WO2003053336A2/en active IP Right Grant
- 2002-11-06 IL IL16250502A patent/IL162505A0/en not_active IP Right Cessation
- 2002-11-06 MX MXPA04006039A patent/MXPA04006039A/en active IP Right Grant
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2004
- 2004-06-10 ZA ZA200404614A patent/ZA200404614B/en unknown
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EP1455778A2 (en) | 2004-09-15 |
AU2002352501A1 (en) | 2003-07-09 |
WO2003053336A2 (en) | 2003-07-03 |
JP2005518381A (en) | 2005-06-23 |
IL162505A0 (en) | 2005-11-20 |
WO2003053336A3 (en) | 2003-11-27 |
EP1455778A4 (en) | 2007-09-12 |
NZ533439A (en) | 2006-06-30 |
CA2470603A1 (en) | 2003-07-03 |
ZA200404614B (en) | 2005-08-29 |
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