MX368750B - Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular. - Google Patents

Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular.

Info

Publication number
MX368750B
MX368750B MX2018010528A MX2018010528A MX368750B MX 368750 B MX368750 B MX 368750B MX 2018010528 A MX2018010528 A MX 2018010528A MX 2018010528 A MX2018010528 A MX 2018010528A MX 368750 B MX368750 B MX 368750B
Authority
MX
Mexico
Prior art keywords
pharmaceutical compositions
compositions containing
application
tissue repair
oil based
Prior art date
Application number
MX2018010528A
Other languages
English (en)
Inventor
Vázquez Cervantes Laura
Agustín Rogelio Magaña Castro José
ARMENDÁRIZ BORUNDA Juan
Original Assignee
Cell Therapy And Tech S A De C V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Therapy And Tech S A De C V filed Critical Cell Therapy And Tech S A De C V
Priority to MX2018010528A priority Critical patent/MX368750B/es
Priority to JP2021537019A priority patent/JP7421558B2/ja
Priority to PCT/MX2019/000093 priority patent/WO2020046102A2/es
Priority to BR112021003877-9A priority patent/BR112021003877A2/pt
Priority to CR20210161A priority patent/CR20210161A/es
Priority to CA3111314A priority patent/CA3111314A1/en
Priority to CN201980064402.9A priority patent/CN113056257A/zh
Priority to PE2021000269A priority patent/PE20212365A1/es
Priority to EP19855904.9A priority patent/EP3842030A2/en
Priority to AU2019329007A priority patent/AU2019329007A1/en
Priority to US17/272,144 priority patent/US20210401989A1/en
Priority to UY0001038355A priority patent/UY38355A/es
Priority to ARP190102459A priority patent/AR116033A1/es
Publication of MX368750B publication Critical patent/MX368750B/es
Priority to CL2021000509A priority patent/CL2021000509A1/es
Priority to IL281142A priority patent/IL281142A/en
Priority to CONC2021/0003927A priority patent/CO2021003927A2/es
Priority to ECSENADI202122187A priority patent/ECSP21022187A/es
Priority to JP2024002910A priority patent/JP2024029232A/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/342—Alcohols having more than seven atoms in an unbroken chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

La presente invención describe composiciones farmacéuticas semisólidas conteniendo Pirfenidona, que ofrece ventajas sobre otras formas farmacéuticas de administración cutánea conocidas en el estado de la técnica, gracias a sus características de permeabilidad y absorción, que es útil en el tratamiento para la restauración de los tejidos que han sufrido pérdida o degradación de matriz extracelular dando como resultado la formación de arrugas o adelgazamiento de la piel.
MX2018010528A 2018-08-31 2018-08-31 Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular. MX368750B (es)

Priority Applications (18)

Application Number Priority Date Filing Date Title
MX2018010528A MX368750B (es) 2018-08-31 2018-08-31 Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular.
AU2019329007A AU2019329007A1 (en) 2018-08-31 2019-08-23 Semi-solid, oil-based pharmaceutical compositions containing pirfenidone for application in tissue repair
US17/272,144 US20210401989A1 (en) 2018-08-31 2019-08-23 Semi-solid, oil-based pharmaceutical compositions containing pirfenidone for application in tissue repair
BR112021003877-9A BR112021003877A2 (pt) 2018-08-31 2019-08-23 composições farmacêuticas à base de óleo semissólidas que contêm pirfenidona para aplicação em reparo tecidual
CR20210161A CR20210161A (es) 2018-08-31 2019-08-23 Composiciones farmacéuticas semisólidas de base oleosa conteniendo pirfenidona para su aplicación en la reparación tisular
CA3111314A CA3111314A1 (en) 2018-08-31 2019-08-23 Semi-solid oil-based pharmaceutical compositions containing pirfenidone for application in tissue repair
CN201980064402.9A CN113056257A (zh) 2018-08-31 2019-08-23 应用于组织修复的含有吡非尼酮的半固体的基于油的药物组合物
PE2021000269A PE20212365A1 (es) 2018-08-31 2019-08-23 Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular
EP19855904.9A EP3842030A2 (en) 2018-08-31 2019-08-23 Semi-solid, oil-based pharmaceutical compositions containing pirfenidone for application in tissue repair
JP2021537019A JP7421558B2 (ja) 2018-08-31 2019-08-23 組織修復に適用されるピルフェニドンを含有する半固体油性医薬組成物
PCT/MX2019/000093 WO2020046102A2 (es) 2018-08-31 2019-08-23 Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular
UY0001038355A UY38355A (es) 2018-08-31 2019-08-29 Composiciones farmacéuticas semisólidas de base oleosa conteniendo pirfenidona para su aplicación en la reparación tisular
ARP190102459A AR116033A1 (es) 2018-08-31 2019-08-29 Composiciones farmacéuticas semisólidas de base oleosa conteniendo pirfenidona para su aplicación en la reparación tisular
CL2021000509A CL2021000509A1 (es) 2018-08-31 2021-02-26 Composiciones farmacéuticas semisólidas de base oleosa conteniendo pirfenidona para su aplicación en la reparación tisular
IL281142A IL281142A (en) 2018-08-31 2021-02-28 Oil-based semi-solid pharmaceutical preparations containing pirfenidone for use in tissue repair
CONC2021/0003927A CO2021003927A2 (es) 2018-08-31 2021-03-29 Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular
ECSENADI202122187A ECSP21022187A (es) 2018-08-31 2021-03-30 Composiciones farmacéuticas semisólidas de base oleosa conteniendo pirfenidona para su aplicación en la reparación tisular
JP2024002910A JP2024029232A (ja) 2018-08-31 2024-01-12 組織修復に適用されるピルフェニドンを含有する半固体油性医薬組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2018010528A MX368750B (es) 2018-08-31 2018-08-31 Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular.

Publications (1)

Publication Number Publication Date
MX368750B true MX368750B (es) 2019-10-15

Family

ID=69513965

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018010528A MX368750B (es) 2018-08-31 2018-08-31 Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular.

Country Status (17)

Country Link
US (1) US20210401989A1 (es)
EP (1) EP3842030A2 (es)
JP (2) JP7421558B2 (es)
CN (1) CN113056257A (es)
AR (1) AR116033A1 (es)
AU (1) AU2019329007A1 (es)
BR (1) BR112021003877A2 (es)
CA (1) CA3111314A1 (es)
CL (1) CL2021000509A1 (es)
CO (1) CO2021003927A2 (es)
CR (1) CR20210161A (es)
EC (1) ECSP21022187A (es)
IL (1) IL281142A (es)
MX (1) MX368750B (es)
PE (1) PE20212365A1 (es)
UY (1) UY38355A (es)
WO (1) WO2020046102A2 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007009796A (es) 2007-08-14 2009-02-25 Cell Therapy And Technology S Gel conteniendo pirfenidona.
MX2011007675A (es) 2011-07-19 2012-07-11 Cell Therapy And Technology S A De C V Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas.
MX346763B (es) 2012-03-28 2017-03-31 Cell Therapy And Tech S A De C V Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné.
MX356551B (es) 2012-08-23 2018-06-04 Grupo Medifarma S A De C V Star Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné.
MX366086B (es) 2017-08-15 2019-06-27 Cell Therapy And Tech S A De C V Composicion topica semisolida conteniendo un agente antimicrobiano y pirfenidona para el tratamiento de daños cronicos de la piel.
CN117653587A (zh) * 2022-09-06 2024-03-08 南京迈诺威医药科技有限公司 一种含有吡非尼酮的局部外用制剂及其用途

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Publication number Priority date Publication date Assignee Title
JPH02215719A (ja) 1989-02-15 1990-08-28 Yamauchi Akitomo 線維化病変組織の修復並びに線維化病変の阻止剤
DE69431433T2 (de) * 1993-05-07 2003-12-04 Solomon B. Margolin Zusammensetzungen und verfahren zur reparatur und vorbeugung fibrotischer verletzungen
CA2322994A1 (en) * 1998-03-17 1999-09-23 Solomon B. Margolin Topical antiseptic compositions and methods
CH696420A5 (de) * 2002-09-13 2007-06-15 Mepha Ag Neue stabile Zubereitungen von Alkyl-, Phenyl-Pyridonen für topische Anwendung.
MX2007009796A (es) * 2007-08-14 2009-02-25 Cell Therapy And Technology S Gel conteniendo pirfenidona.
CN101972225A (zh) * 2010-10-13 2011-02-16 北京诚创康韵医药科技有限公司 一种含吡非尼酮的凝胶组合物
EP2675449B1 (en) * 2011-02-15 2019-04-24 Aclaris Therapeutics, Inc. Pharmaceutical cream compositions of oxymetazoline for treating symptoms of rosacea
CN102670600A (zh) * 2011-03-12 2012-09-19 赵海静 一种抑制瘢痕和促进创口愈合的医药产品,其制备方法和应用
MX346763B (es) * 2012-03-28 2017-03-31 Cell Therapy And Tech S A De C V Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné.
AU2014233362A1 (en) * 2013-03-15 2015-10-01 Medicis Pharmaceutical Corporation Topical compositions of flunisolide and methods of treatment
EP3086786A4 (en) * 2013-12-27 2017-06-14 Scioderm Inc. Keloid reduction using topical allantoin
CA2954061C (en) * 2014-07-11 2023-01-24 Novan, Inc. Topical antiviral compositions and methods of using the same
RS63402B1 (sr) * 2015-05-21 2022-08-31 Dermavant Sciences GmbH Topikalne farmaceutske kompozicije

Also Published As

Publication number Publication date
PE20212365A1 (es) 2021-12-21
US20210401989A1 (en) 2021-12-30
WO2020046102A3 (es) 2020-09-10
CL2021000509A1 (es) 2021-07-19
BR112021003877A2 (pt) 2021-05-18
AR116033A1 (es) 2021-03-25
ECSP21022187A (es) 2021-06-30
WO2020046102A2 (es) 2020-03-05
CR20210161A (es) 2021-08-19
JP2024029232A (ja) 2024-03-05
CN113056257A (zh) 2021-06-29
CO2021003927A2 (es) 2021-07-30
JP2022508418A (ja) 2022-01-19
AU2019329007A1 (en) 2021-04-01
EP3842030A2 (en) 2021-06-30
UY38355A (es) 2020-03-31
IL281142A (en) 2021-06-30
CA3111314A1 (en) 2020-03-05
JP7421558B2 (ja) 2024-01-24

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