KR840005083A - 항고혈압제로서 유용한 아미노산유도체의 제조방법 - Google Patents

항고혈압제로서 유용한 아미노산유도체의 제조방법 Download PDF

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Publication number
KR840005083A
KR840005083A KR1019840000192A KR840000192A KR840005083A KR 840005083 A KR840005083 A KR 840005083A KR 1019840000192 A KR1019840000192 A KR 1019840000192A KR 840000192 A KR840000192 A KR 840000192A KR 840005083 A KR840005083 A KR 840005083A
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KR
South Korea
Prior art keywords
amino acid
acid derivatives
antihypertensive agents
derivatives useful
preparing amino
Prior art date
Application number
KR1019840000192A
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English (en)
Inventor
에이 파체트(외 3) 아더
Original Assignee
제임스 에프·너우톤
맬크 앤드 캄파니, 인코포레이티드
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25513965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR840005083(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 제임스 에프·너우톤, 맬크 앤드 캄파니, 인코포레이티드 filed Critical 제임스 에프·너우톤
Publication of KR840005083A publication Critical patent/KR840005083A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

내용 없음

Description

항고혈압제로서 유용한 아미노산유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. 다음 일반식 (2)의 케톤을 환원제의 존재하에 다음 일반식 (3)의 디펩티드와 반응시켜서 일반식 (1)의 화합물을 제조하는 방법
  3. 식중,
  6. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840000192A 1978-12-11 1984-01-17 항고혈압제로서 유용한 아미노산유도체의 제조방법 KR840005083A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96824978A 1978-12-11 1978-12-11
US968249 1978-12-11

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR7904273A Division KR850000847B1 (ko) 1978-12-11 1979-12-11 아미노산 유도체의 제조방법

Publications (1)

Publication Number Publication Date
KR840005083A true KR840005083A (ko) 1984-11-03

Family

ID=25513965

Family Applications (3)

Application Number Title Priority Date Filing Date
KR7904273A KR850000847B1 (ko) 1978-12-11 1979-12-11 아미노산 유도체의 제조방법
KR1019840000192A KR840005083A (ko) 1978-12-11 1984-01-17 항고혈압제로서 유용한 아미노산유도체의 제조방법
KR1019840002123A KR850000846B1 (ko) 1978-12-11 1984-04-21 아미노산 유도체의 제조방법

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR7904273A KR850000847B1 (ko) 1978-12-11 1979-12-11 아미노산 유도체의 제조방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019840002123A KR850000846B1 (ko) 1978-12-11 1984-04-21 아미노산 유도체의 제조방법

Country Status (33)

Country Link
US (2) US4374829A (ko)
EP (1) EP0012401B1 (ko)
JP (3) JPS5581845A (ko)
KR (3) KR850000847B1 (ko)
AR (1) AR231971A1 (ko)
AU (1) AU530380B2 (ko)
BG (6) BG39294A3 (ko)
CA (4) CA1302005C (ko)
CS (1) CS237311B2 (ko)
DD (1) DD148770A5 (ko)
DE (2) DE2966767D1 (ko)
DK (1) DK165455C (ko)
EG (1) EG14182A (ko)
ES (2) ES486786A0 (ko)
FI (1) FI68405C (ko)
GR (1) GR72251B (ko)
HK (1) HK27487A (ko)
HU (1) HU182902B (ko)
IE (1) IE48922B1 (ko)
IL (1) IL58849A (ko)
LU (1) LU90173I2 (ko)
MA (1) MA18664A1 (ko)
NL (4) NL930008I2 (ko)
NO (3) NO151622C (ko)
NZ (1) NZ192312A (ko)
PH (1) PH24268A (ko)
PL (2) PL126126B1 (ko)
PT (1) PT70542A (ko)
RO (4) RO85073B (ko)
SU (1) SU1287756A3 (ko)
YU (3) YU42655B (ko)
ZA (1) ZA796688B (ko)
ZW (1) ZW24479A1 (ko)

Families Citing this family (387)

* Cited by examiner, † Cited by third party
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