JPH07503477A - バッカチン3および10‐デアセチルバッカチン3の新規誘導体,それらの製造およびそれらを含有する医薬組成物 - Google Patents
バッカチン3および10‐デアセチルバッカチン3の新規誘導体,それらの製造およびそれらを含有する医薬組成物Info
- Publication number
- JPH07503477A JPH07503477A JP5513823A JP51382393A JPH07503477A JP H07503477 A JPH07503477 A JP H07503477A JP 5513823 A JP5513823 A JP 5513823A JP 51382393 A JP51382393 A JP 51382393A JP H07503477 A JPH07503477 A JP H07503477A
- Authority
- JP
- Japan
- Prior art keywords
- group
- carbon atoms
- groups
- general formula
- once
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR92/01381 | 1992-02-07 | ||
FR9201381A FR2687151B1 (fr) | 1992-02-07 | 1992-02-07 | Nouveaux derives de la baccatine iii et de la desacetyl-10 baccatine iii, leur preparation et les compositions pharmaceutiques qui les contiennent. |
PCT/FR1993/000112 WO1993016060A1 (fr) | 1992-02-07 | 1993-02-04 | Nouveaux derives de la baccatine iii et de la desacetyl-10 baccatine iii, leur preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH07503477A true JPH07503477A (ja) | 1995-04-13 |
Family
ID=9426426
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5513823A Pending JPH07503477A (ja) | 1992-02-07 | 1993-02-04 | バッカチン3および10‐デアセチルバッカチン3の新規誘導体,それらの製造およびそれらを含有する医薬組成物 |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0625148A1 (sv) |
JP (1) | JPH07503477A (sv) |
AU (1) | AU3505093A (sv) |
CA (1) | CA2127372A1 (sv) |
CZ (1) | CZ187294A3 (sv) |
FI (1) | FI943645A0 (sv) |
FR (1) | FR2687151B1 (sv) |
HU (1) | HU9402292D0 (sv) |
MX (1) | MX9300628A (sv) |
NO (1) | NO942910L (sv) |
SK (1) | SK92794A3 (sv) |
TW (1) | TW242139B (sv) |
WO (1) | WO1993016060A1 (sv) |
ZA (1) | ZA93821B (sv) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998002426A1 (fr) * | 1996-07-15 | 1998-01-22 | Kabushiki Kaisha Yakult Honsha | Derives de taxane et medicaments les contenant |
WO1999014209A1 (fr) * | 1997-09-17 | 1999-03-25 | Kabushiki Kaisha Yakult Honsha | Nouveaux derives de taxane |
US6509484B2 (en) | 1993-02-05 | 2003-01-21 | Napro Biotherapeutics, Inc. | Synthesis of taxol, taxol analogs and their intermediates with variable a-ring side chain structures and compositions thereof |
JP2011517455A (ja) * | 2008-03-31 | 2011-06-09 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | C(10)エチルエステルおよびc(10)シクロプロピルエステル置換タキサン |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5698582A (en) * | 1991-07-08 | 1997-12-16 | Rhone-Poulenc Rorer S.A. | Compositions containing taxane derivatives |
US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
FR2696459B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
MX9307777A (es) | 1992-12-15 | 1994-07-29 | Upjohn Co | 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN. |
US5684175A (en) * | 1993-02-05 | 1997-11-04 | Napro Biotherapeutics, Inc. | C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor |
US5965739A (en) * | 1993-06-11 | 1999-10-12 | Pharmacia & Upjohn Company | Δ6,7 -taxols antineoplastic use and pharmaceutical compositions containing them |
IL127599A (en) * | 1994-01-28 | 2004-06-01 | Upjohn Co | Process for preparing isotaxol analogs |
GB9512471D0 (en) * | 1995-06-20 | 1995-08-23 | Pharmacia Spa | Method for the preparation of taxol and its derivatives |
US6107497A (en) * | 1996-02-29 | 2000-08-22 | Napro Biotherapeutics, Inc. | Intermediate for use in docetaxel synthesis and production method therefor |
US5750737A (en) * | 1996-09-25 | 1998-05-12 | Sisti; Nicholas J. | Method for paclitaxel synthesis |
WO2002066448A1 (en) * | 2001-02-20 | 2002-08-29 | Dabur India Limited | Method of preparation of paclitaxel (taxol) using 3-(alk-2-ynyloxy) carbonyl-5-oxazolidine carboxylic acid |
US20110118473A1 (en) * | 2007-08-22 | 2011-05-19 | 6570763 Canada Inc. | Process for converting 9-dihydro-13acetylbaccatin iii paclitaxel and docetaxel |
-
1992
- 1992-02-07 FR FR9201381A patent/FR2687151B1/fr not_active Expired - Fee Related
-
1993
- 1993-02-04 EP EP93904152A patent/EP0625148A1/fr not_active Withdrawn
- 1993-02-04 SK SK927-94A patent/SK92794A3/sk unknown
- 1993-02-04 HU HU9402292A patent/HU9402292D0/hu unknown
- 1993-02-04 AU AU35050/93A patent/AU3505093A/en not_active Abandoned
- 1993-02-04 MX MX9300628A patent/MX9300628A/es unknown
- 1993-02-04 CA CA002127372A patent/CA2127372A1/fr not_active Abandoned
- 1993-02-04 WO PCT/FR1993/000112 patent/WO1993016060A1/fr not_active Application Discontinuation
- 1993-02-04 TW TW082100756A patent/TW242139B/zh active
- 1993-02-04 CZ CZ941872A patent/CZ187294A3/cs unknown
- 1993-02-04 JP JP5513823A patent/JPH07503477A/ja active Pending
- 1993-02-05 ZA ZA93821A patent/ZA93821B/xx unknown
-
1994
- 1994-08-05 FI FI943645A patent/FI943645A0/sv not_active Application Discontinuation
- 1994-08-05 NO NO942910A patent/NO942910L/no unknown
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6509484B2 (en) | 1993-02-05 | 2003-01-21 | Napro Biotherapeutics, Inc. | Synthesis of taxol, taxol analogs and their intermediates with variable a-ring side chain structures and compositions thereof |
WO1998002426A1 (fr) * | 1996-07-15 | 1998-01-22 | Kabushiki Kaisha Yakult Honsha | Derives de taxane et medicaments les contenant |
CN1097044C (zh) * | 1996-07-15 | 2002-12-25 | 亚库尔特株式会社总社 | 紫杉烷衍生物以及含有该衍生物的药物 |
WO1999014209A1 (fr) * | 1997-09-17 | 1999-03-25 | Kabushiki Kaisha Yakult Honsha | Nouveaux derives de taxane |
US6136808A (en) * | 1997-09-17 | 2000-10-24 | Kabushiki Kaisha Yakult Honsha | Taxane derivatives |
JP2011517455A (ja) * | 2008-03-31 | 2011-06-09 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | C(10)エチルエステルおよびc(10)シクロプロピルエステル置換タキサン |
Also Published As
Publication number | Publication date |
---|---|
AU3505093A (en) | 1993-09-03 |
FR2687151B1 (fr) | 1994-03-25 |
WO1993016060A1 (fr) | 1993-08-19 |
TW242139B (sv) | 1995-03-01 |
MX9300628A (es) | 1993-08-01 |
EP0625148A1 (fr) | 1994-11-23 |
NO942910L (no) | 1994-08-05 |
ZA93821B (en) | 1993-09-09 |
FI943645A (sv) | 1994-08-05 |
CA2127372A1 (fr) | 1993-08-19 |
FI943645A0 (sv) | 1994-08-05 |
NO942910D0 (sv) | 1994-08-05 |
FR2687151A1 (fr) | 1993-08-13 |
CZ187294A3 (en) | 1995-01-18 |
SK92794A3 (en) | 1995-04-12 |
HU9402292D0 (en) | 1994-11-28 |
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