JP6279268B2 - Vial adapter - Google Patents

Description

  The present invention relates to a vial adapter connected to a vial.

  Generally, when a drug solution is collected from a vial, a bare metal injection needle is directly punctured into a rubber stopper (plug body) of the vial and sucked. However, when the exposed metal injection needle is directly punctured into the stopper, a needle stick accident caused by the injection needle may occur. Therefore, a vial adapter has been proposed that enables easy preparation of a medicine without using a bare injection needle as a member that punctures the stopper.

  By the way, not all vials distributed in Japan are manufactured according to a unified standard, and there are cases where the shape and dimensions differ for each manufacturer and product. As one example, there is an outer diameter of a plurality of vial top surfaces (surfaces provided with stoppers).

  In Patent Document 1, a shroud is provided with a first set of claws and a second set of pawls that snap onto the vial seal, and the length of the second set of pawls is the same as that of the first set of pawls. A vial adapter having a second length greater than one length, wherein the first set of pawls engages a larger diameter vial seal and the second set of pawls has a smaller diameter vial seal. A vial adapter is disclosed in which a first length and a second length are selected to engage.

  According to Patent Document 1, it is possible to use a single vial adapter for vials having different diameters of the vial sealing portion.

Japanese Patent No. 4509568

  However, since the vial adapter disclosed in Patent Document 1 is configured to have different claws (a first set of claws and a second set of claws) for the purpose of holding vials having different diameters of the seal parts, There is a problem that it is necessary to provide a claw to be used for each vial having a different diameter in a single vial adapter, and it is difficult to arrange each claw having a sufficient holding force capable of holding each vial. is there.

  In view of the above problems, an object of the present invention is to sufficiently secure a locking member such as a claw capable of locking a plurality of vials having different diameters (outer diameters) of a vial sealing part (vial top surface). It is to provide a vial adapter.

In order to solve the above-described problems, a vial adapter as a first aspect of the present invention includes a locking member that comes into contact with an outer wall of a vial having a stopper and locks the vial, and the stopper of the vial. a piercing member having a needle-like portion whose tip is inserted, while being supported by the piercing member, and a said engaging locking member holder locking member is mounted, the locking member holder, the engagement The stop member has a guide portion that guides the vial so as to move in the radial direction of the substantially circular top surface of the vial, and the guide portion regulates the position of the locking member in the radial direction to a predetermined position. has a position regulating portion, characterized in that the locking member, by said movable in the radial direction in accordance with the outer diameter of the top surface, it is possible to lock the different vials of the outer diameter It is what.

Vial adapter according to an embodiment of the present invention, the locking member holder is rotatably supported about said needle portion to the piercing member, the locking member holder with respect to the piercing member It is preferable that the locking member moves in the radial direction by rotating.

As one embodiment of the present invention, the guide portion is a first guide portion in which the distance from the center in the radial direction gradually increases or decreases as the locking member holder advances in the rotation direction , and the piercing member is The second guide portion extending in the radial direction, and the locking member is guided by the first guide portion and the second guide portion when the locking member holder rotates, It is preferable to move in the radial direction.

  The vial adapter as one embodiment of the present invention defines a connection port of an insertion member inserted from the outside and includes a connection member supported by the piercing member, and the locking member holder includes the needle It is preferable that the needle member is sandwiched between the piercing member and the connection member in the insertion direction of the needle-like part, and the movement of the needle-like part in the insertion direction and the direction opposite to the insertion direction is restricted.

  As one Embodiment of this invention, it is preferable that the said locking member is arrange | positioned cyclically | annularly, and is the some locking piece which latches the said vial while contacting the said outer wall of the said vial.

  As one embodiment of the present invention, the locking piece is provided at an extension portion extending in a direction substantially orthogonal to the top surface of the vial, and at one end of the extension portion, and provided on the outer wall of the vial. It is preferable to provide a claw portion that enters an annular space defined by the constricted portion.

  As an embodiment of the present invention, in a state where the claw portion enters the annular space, the claw portion is urged in a direction opposite to the insertion direction of the needle-like portion and pressed against the outer wall of the vial. It is preferable to provide a biasing member.

  According to the present invention, it is possible to sufficiently secure a locking member that can lock a plurality of vials having different vial outer diameters.

It is sectional drawing which shows the vial adapter 1 as one Embodiment of this invention in the same attitude | position as the state connected to the vial. It is a side view of the vial adapter 1 in the same attitude | position as FIG. It is sectional drawing which shows the vial adapter 1 in the same attitude | position as the state connected to the vial 110. FIG. It is a side view of the vial adapter 1 in the same attitude | position as FIG. 4 is a perspective view showing a single piece of a locking piece 32. FIG. It is a perspective view which shows the single piece of the locking piece 32 at the time of seeing from the position different from FIG. It is a disassembled perspective view which shows one state of the moving mechanism of the latching member 6 in the vial adapter 1. FIG. It is a disassembled perspective view which shows another state of the moving mechanism of the latching member 6 in the vial adapter 1. FIG. 4 is a perspective view showing only a plurality of locking pieces 32a and a piercing member 3 of the vial adapter 1. FIG. It is sectional drawing which shows the vial adapter connection body 70a provided with the vial 100 as the vial adapter connection body 70 which is one Embodiment of this invention. It is sectional drawing which shows the vial adapter connection body 70b provided with the vial 110 as the vial adapter connection body 70. FIG.

  Hereinafter, embodiments of a vial adapter and a vial adapter connector according to the present invention will be described with reference to FIGS. In addition, the same code | symbol is attached | subjected to the common member in each figure.

  First, one embodiment of the vial adapter according to the present invention will be described. 1-4 is a figure which shows the structure of the vial adapter 1 in this embodiment.

  Specifically, FIGS. 1 and 2 show a state in which a substantially circular top surface 102 provided with a rubber stopper 101a as a stopper 101 is connected to a vial 100 (see FIG. 10) having an outer diameter of 20 mm. It is sectional drawing and the side view which show the vial adapter 1 in the same attitude | position. 3 and 4 are a cross-sectional view and a side view showing the vial adapter 1 in the same posture as that connected to a vial 110 (see FIG. 11) whose top surface 102 has an outer diameter of 13 mm. Details of the vials 100 and 110 will be described later (see FIGS. 10 and 11).

  As shown in FIGS. 1 and 3, the vial adapter 1 includes a connecting member 2, a piercing member 3, a connecting member 4, a locking member holder 5, a locking member 6, a biasing member 50, Is provided.

  Details of each member and a characteristic part constituted by each member in the present embodiment will be described below. Since each member constituting the vial adapter 1 does not depend on the types of vials 100 and 110, for convenience of explanation, “vial 100” is used in the description of each member, but the same applies to “vial 110”. .

[Connection member 2]
As shown in FIGS. 1 and 3, the connection member 2 defines a connection port 7 of an insertion member inserted from the outside and is supported by the piercing member 3 via a connecting member 4 described later.

  Specifically, the connection member 2 has a cylindrical housing 8 that defines a connection port 7 of an insertion member such as a male connector inserted from the outside, and a slit 9, and is located in the connection port 7. 8 is provided with an elastic valve body 10 that is held by the motor 8.

  The housing 8 includes a substantially cylindrical housing body 11 and a cap 12 held on one end side of the housing body 11. The connection port 7 is a hollow portion defined by the housing body 11 and the cap 12, and the insertion member is inserted into the connection port 7 from the outside. Further, the other end side of the housing body 11 is connected to a connecting member 4 to be described later, whereby the housing 8 is indirectly supported by the piercing member 3 through the connecting member 4.

  Specifically, the connection port 7 communicates with the substantially hollow cylindrical first hollow portion 13 and the first hollow portion 13 at a position closer to the inlet side than the first hollow portion 13. And a substantially cylindrical second hollow portion 14 having a small outer diameter in cross section. In addition, the 2nd hollow part 14 in this embodiment is divided by the inner wall 18 of the cap 12, as shown in FIG.1 and FIG.3.

  The elastic valve body 10 is a substantially cylindrical member located in the connection port 7, and defines a substantially columnar hollow portion 15. Specifically, the elastic valve body 10 is continuous with the substantially cylindrical bellows portion 16 positioned in the first hollow portion 13 defined by the housing 8 and one end side of the bellows portion 16, and the first is defined by the housing 8. 2 and a substantially cylindrical cylindrical portion 17 located in the hollow portion 14.

  The bellows portion 16 has a bellows-like wall surface so that the elastic valve body 10 pushed inward of the vial adapter 1 by insertion of the insertion member can be easily elastically deformed in the insertion direction A of the insertion member. The other end portion of the bellows portion 16 (the end portion on the lower side of the bellows portion 16 in FIGS. 1 and 3) is supported by the inner wall of the housing body 11. Specifically, a cylindrical protrusion 65 provided on the inner wall of the housing body 11 enters the other end portion of the bellows portion 16 and is partitioned by the hollow portion 15 of the elastic valve body 10 and the cylindrical tube portion 65. The other end portion of the bellows portion 16 is supported by the housing body 11 in a state where a substantially cylindrical hollow portion 66 communicating with a connection hollow portion 28 of the connection member 4 described later is connected.

  In a state where the insertion member is not inserted into the connection port 7, the cylindrical portion 17 is compressed by the inner wall of the housing 8 that defines the second hollow portion 14 (in this embodiment, the inner wall 18 of the cap 12). 2 Located in the hollow part 14. The cylindrical portion 17 includes a top surface portion 19 at the other end opposite to the one end portion continuous with the bellows portion 16, and a slit 9 is formed in the top surface portion 19.

  When the housing 8 and the elastic valve body 10 have the above-described configuration, the insertion member is inserted into the connection port 7 from the outside, and the elastic valve body 10 is pushed into the vial adapter 1 inward. Is elastically deformed so that the bellows portion 16 of the elastic valve body 10 is folded, and when the cylindrical portion 17 passes through the second hollow portion 14 and reaches the position of the first hollow portion 13, the cylindrical portion 17 expands in diameter. Then, the slit 9 of the top surface portion 19 is opened, and the insertion member can enter the hollow portion 15 defined by the elastic valve body 10 through the slit 9.

  Examples of the material of the housing main body 11 and the cap 12 constituting the housing 8 include polyolefins such as polyethylene, polypropylene, and ethylene-propylene copolymer; ethylene-vinyl acetate copolymer (EVA); polyvinyl chloride; polyvinylidene chloride Polystyrene; Polyamide; Polyimide; Polyamideimide; Polycarbonate; Poly- (4-methylpentene-1); Ionomer; Acrylic resin; Polymethylmethacrylate; Acrylonitrile-butadiene-styrene copolymer (ABS resin); Acrylonitrile-styrene copolymer Polymer (AS resin); butadiene-styrene copolymer; polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polycyclohexane terephthalate (PCT), etc. Polyether; Polyetherketone (PEK); Polyetheretherketone (PEEK); Polyetherimide; Polyacetal (POM); Polyphenyleneoxide; Modified polyphenyleneoxide; Polysulfone; Polyethersulfone; Polyphenylenesulfide; Polyarylate; Various resin materials such as group polyester (liquid crystal polymer); polytetrafluoroethylene, polyvinylidene fluoride, and other fluorine-based resins are listed. Also, a blend or a polymer alloy containing one or more of these may be used. In addition, various glass materials, ceramic materials, and metal materials may be used.

  The elastic valve body 10 is molded and formed so as to be elastically deformable. Examples of the material of the elastic valve body 10 include natural rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, nitrile rubber, chloroprene rubber, butyl rubber, acrylic rubber, ethylene-propylene rubber, hydrin rubber, urethane rubber, silicone rubber, Various rubber materials such as fluoro rubber, various heat such as styrene, polyolefin, polyvinyl chloride, polyurethane, polyester, polyamide, polybutadiene, trans polyisoprene, fluoro rubber, chlorinated polyethylene, etc. A plastic elastomer may be mentioned, and one or a mixture of two or more of these may be used.

  The housing 8 in the present embodiment is configured by the housing main body 11 and the cap 12, but is not limited to this configuration. For example, the housing main body 11 and the cap 12 are integrally molded to form a single unit. You may comprise by the member of.

  In addition, the elastic valve body 10 in the present embodiment uses a substantially cylindrical elastic valve body having the bellows portion 16, but is not limited to this. For example, the elastic valve body 10 has a substantially disc-shaped elasticity in which slits are formed. A valve body may be used.

  Furthermore, when an insertion member using a hollow needle is used, for example, as a connection member including a housing that defines a connection port, and a rubber plug that is held by the housing and closes one end of the connection port. Good. In such a case, the hollow needle penetrates the rubber stopper, and the hollow portion of the hollow needle and the connection port communicate with each other.

[Puncture member 3]
As shown in FIGS. 1 and 3, the piercing member 3 is continuous with the needle-like part 20 whose tip is inserted into the stopper 101 of the vial 100 (see FIG. 10), and one end of the needle-like part 20. A disc-shaped flange portion 21 extending in a direction C perpendicular to the insertion direction B of the needle-like portion 20 (in the present embodiment, the same direction as the insertion direction A of the insertion member), and the needle-like portion 20 of the flange portion 21. And a substantially cylindrical projection 22 that is continuous with the flange 21 on a plane opposite to the substantially circular plane that is continuous with the flange 21 and projects from the plane of the flange 21. The piercing member 3 defines a substantially cylindrical hollow portion 23 that penetrates the needle-shaped portion 20, the flange portion 21, and the protruding portion 22 in the insertion direction B of the needle-shaped portion 20.

  The needle-like part 20 is a part that can be inserted into the vial 100 through the stopper 101 of the vial 100. When the distal end portion of the needle-like portion 20 enters the vial 100 through the stopper 101, one end of the hollow portion 23 on the needle-like portion 20 side communicates with the space in the vial 100.

  The flange portion 21 is continuous with the proximal end portion 24 of the needle-like portion 20, and extends in a direction C orthogonal to the insertion direction B of the needle-like portion 20. Of the flange portion 21, a locking member holder 5 and a locking member 6, which will be described later, are supported by a plane opposite to the substantially circular plane that is continuous with the proximal end portion 24 of the needle-shaped portion 20. Details of this will be described later.

  The substantially cylindrical protruding portion 22 is provided so as to protrude from the substantially circular plane of the flange portion 21. When the flange portion 21 and the protruding portion 22 are viewed in the insertion direction B, the outer shapes of the flange portion 21 and the protruding portion 22 are concentric circles centering on the needle-shaped portion 20, and the top surface of the protruding portion 22 covers the central region. The annular plane of the flange portion 21 constitutes the external region.

  Here, the protruding portion 22 enters a cylindrical shaft hole 29 provided in the locking member holder 5 described later, and constitutes a rotation shaft of the locking member holder 5. That is, the locking member holder 5 is pivotally supported by the columnar protrusion 22. In a state where the locking member holder 5 is pivotally supported by the projecting portion 22, the locking member holder 5 and the locking member 6 are sandwiched and held by the plane of the flange portion 21 and a connecting member 4 described later. As described above, when the protruding portion 22 is viewed in the insertion direction B, the protruding portion 22 has a substantially circular outer shape centering on the needle-shaped portion 20, so that the locking member holder 5 has another term. In this case, in a plane orthogonal to the insertion direction B of the needle-like part 20, the needle-like part 20 can be rotated around the central axis.

  A second guide portion 31 that guides the locking member 6 (described later) to move in the radial direction D of the locking member holder 5 is provided on the annular flat surface of the flange portion 21 that is continuous with the protruding portion 22. ing. Specifically, the 2nd guide part 31 in this embodiment is the convex slide rail 31a extended in the radial direction D (refer FIG. 1, FIG. 8). Details of this point will be described later.

  As the material of the piercing member 3, for example, the same material as that of the housing 8 of the connecting member 2 described above can be used.

[Connecting member 4]
The connecting member 4 is a member that connects the connecting member 2 and the piercing member 3. Specifically, the connecting member 4 includes a main body portion 25 having a substantially cylindrical outer shape, and a substantially disk-shaped flange portion 26 continuous with one end of the main body portion 25.

  The piercing member 3 is supported by the connecting member 4 at one end of the connecting member 4 on the flange 26 side, and the connecting member 2 is supported by the connecting member 4 at the other end opposite to the flange 26. .

  Specifically, the flange portion 26 of the connecting member 4 is formed with a substantially cylindrical concave portion 27 that accommodates the top of the protruding portion 22 of the piercing member 3, and the protruding portion 22 fits into the concave portion 27. Thus, the piercing member 3 is supported by the connecting member 4. The substantially cylindrical recess 27 is a groove defined by the inner wall of the flange portion 26 and a part of the inner wall of the main body portion 25.

  The main body 25 of the connecting member 4 is also formed with an annular groove 67 into which the end of the cylindrical housing main body 11 of the connecting member 2 is fitted, and one end of the housing main body 11 to which the cap 12 is attached. The connecting member 2 is supported by the connecting member 4 by fitting the other end opposite to the portion into the annular groove 67.

  In addition, between the connection member 2 and the connection member 4, and between the piercing member 3 and the connection member 4 are adhere | attached, for example with an adhesive agent, the connection member 2 and the piercing member 3 become the connection member 4. It is fixed against.

  Here, in a state where the connecting member 2 and the piercing member 3 are fixed to the connecting member 4, the connecting member 4 includes the hollow portion 15 of the elastic valve body 10 and the hollow portion of the piercing member 3 in the connecting member 2. The connection hollow part 28 which connects 23 is divided. Further, in this state, since the protruding portion 22 of the piercing member 3 enters a shaft hole 29 of the locking holder 6 described later, the locking member holder 5 can rotate around the protruding portion 22 as an axis. On the other hand, the locking member holder 5 and the locking member 6 held by the locking member holder 5 are connected to the flange portion 26 of the shaft coupling member 4 and the piercing member 3 in the extending direction B of the needle-like portion 20. The position is regulated between the flange portion 21.

  Moreover, in this embodiment, in the connection position of the piercing member 3 and the connection member 4 where the hollow part 23 of the piercing member 3 and the connection hollow part 28 of the connection member 4 are connected, the hollow part 23 and the connection hollow part 28 An O-ring 60a as a seal member 60 is provided so that the chemical solution can be smoothly moved between the two. The O-ring 60 a is formed at the position sandwiched between the top surface of the protruding portion 22 of the piercing member 3 (the upper surface of the protruding portion 22 in FIGS. 1 and 3) and the bottom surface of the concave portion 27 of the connecting member 4. And it is provided so that the connection hollow part 28 may be enclosed. Thereby, it is suppressed that a chemical | medical solution leaks between the hollow part 23 and the connection hollow part 28. FIG. In this embodiment, the O-ring 60a is used as the seal member 60. However, the present invention is not limited to this. For example, the leakage of the chemical solution may be prevented by welding the piercing member 3 and the connecting member 4. Is possible.

  As the material of the connecting member 4, for example, the same material as that of the housing 8 of the connecting member 2 described above can be used.

  In the present embodiment, the connecting member 4 is provided separately from the connecting member 2 and the piercing member 3. However, a connecting mechanism for connecting both the connecting member 2 and the piercing member 3 is provided. The configuration is not limited to this. Therefore, for example, a connecting portion that can connect both the connecting member 2 and the piercing member 3 may be provided so that the connecting member 2 is directly supported by the piercing member 3.

[Locking member holder 5]
The locking member holder 5 is a member that is supported by the piercing member 3 so as to be rotatable about the needle-like portion 20 of the piercing member 3 and to which a locking member 6 described later is attached. Specifically, the locking member holder 5 has a disk shape, and the protrusion 22 of the piercing member 3 is accommodated in the shaft hole 29 formed in the center of the disk, whereby the flange of the piercing member 3 is accommodated. Between the part 21 and the flange part 26 of the connection member 4, it is supported by the piercing member 3 so that it can rotate centering | focusing on the protrusion part 22 of the piercing member 3. FIG. On the other hand, since the locking member holder 5 is sandwiched between the piercing member 3 and the connecting member 2 in the insertion direction B of the needle-like portion 20 of the piercing member 3, the insertion direction of the needle-like portion 20 Movement in the reverse direction E of B and the insertion direction B is restricted. In the present embodiment, the connecting member 2 is sandwiched between the connecting member 2 and the piercing member 3 via the connecting member 4, but the connecting member 2 is not provided with the connecting member 4 as described above. And the piercing member 3 can be directly sandwiched.

  When the locking member holder 5 is viewed in the insertion direction B of the needle-like portion 20, the rotation direction G of the locking member holder 5 (in this embodiment, the same direction as the circumferential direction F of the locking member holder 5 (FIG. 7 , See FIG. 8)), the distance from the rotation center (the needle-like portion 20 of the piercing member 3) in the radial direction D (in this embodiment, since the rotation center axis is the protrusion 22), the protrusion in the radial direction D The guide long hole 30a is provided as the first guide portion 30 that gradually increases or decreases (the same distance as the distance from the portion 22) (see FIGS. 7 and 8). A protrusion 37 (see FIG. 5) of the locking member 6 described later is fitted in the guide long hole 30a, and when the locking member holder 5 rotates, the guide long hole 30a and the above-described convex shape are formed. The movement direction of the locking member 6 is guided by the slide rail 31a, and the locking member 6 moves only in the radial direction D. Details of the moving mechanism of the locking member 6 will be described later (see FIGS. 7 to 9).

  As a material of the locking member holder 5, for example, the same material as that of the housing 8 of the connection member 2 described above can be used.

[Locking member 6]
The locking member 6 is a member that is held by the locking member holder 5 and that contacts the outer wall of the vial 100 (see FIG. 10) and locks the vial 100. The locking member 6 in the present embodiment is annularly arranged along the circumferential direction F of the substantially disk-shaped locking member holder 5, and comes into contact with the outer wall of the vial 100 and a plurality of locking pieces for locking the vial 100. 32a, 32b, 32c, and 32d. Here, “locking” the vial 100 by the locking member 6 means that the position of the vial 100 relative to the vial adapter 1 is regulated by the locking member 6 so as not to move from a predetermined position or a predetermined range. ing. 5 and 6 are perspective views showing one locking piece 32. FIG.

  As shown in FIGS. 1 and 3, each locking piece 32 extends in a direction H (in the present embodiment, the same direction as the insertion direction B of the needle-like portion 20) substantially orthogonal to the top surface 102 of the vial 100. An extension portion 33, a claw portion 34 provided at one end of the extension portion 33 and entering the annular space 104 defined by the constricted portion 103 provided on the outer wall of the vial 100, and a claw portion of the extension portion 33 34, provided at the other end opposite to the one end provided with 34, and a held portion 35 held by the locking member holder 5.

  The extending portion 33 is a curved plate having a curved shape that follows the peripheral surface of the substantially circular top surface 102 of the vial 100. In the present embodiment, the extending portion 33 includes a plurality of locking pieces 32a, 32b, 32c, and When 32d is viewed in the insertion direction B, the extending portions 33 of the four locking pieces 32a to 32d are arranged on the same circumference (see FIGS. 7 to 9).

  The claw portion 34 protrudes from one end of the extending portion 33 in a direction orthogonal to the insertion direction B, and enters the annular space 104 when the vial adapter 1 is attached to the vial 100 to lock the vial 100.

  The held portion 35 is continuous with the other end of the extending portion 33, and from the other end, the radial direction I of the substantially circular top surface 102 of the vial 100 (in this embodiment, the radial direction D of the locking member holder 5). It extends to the center side in the same direction). As shown in FIGS. 5 and 6, the held portion 35 includes a bottom surface 62 that is continuous with the inner surface 61 that contacts the outer wall of the vial 100 in the extending portion 33 that is a curved plate, and the extending portion 33. An outer surface 63 that does not contact the outer wall of the vial 100 and a continuous top surface 64 are provided. As shown in FIG. 6, the bottom surface 62 of the held portion 35 is formed with a groove 36 that fits into the convex slide rail 31 a (see FIGS. 1 and 9) provided on the piercing member 3. . Further, as shown in FIG. 5, a substantially cylindrical protrusion 37 that enters a guide slot 30 a (see FIGS. 7 and 8) provided in the locking member holder 5 is formed on the top surface 64 of the held portion 35. Is formed. Details of the mechanism by which the locking member 6 is moved by the guide long hole 30a, the convex slide rail 31a, the groove 36, and the protrusion 37 will be described later (see FIGS. 7 to 9).

  As a material of the locking member 6, for example, a material similar to that of the housing 8 of the connection member 2 described above can be used. In addition, the plurality of locking pieces 32a to 32d in the present embodiment are provided at four positions where the central angle is shifted by 90 degrees in the circumferential direction F. However, the present invention is not limited to this configuration. The number can be changed as appropriate according to a specific purpose or application, such as a configuration in which a total of eight locking pieces are provided at positions where the angles are shifted by 45 degrees. However, when the number of the locking pieces 32 is an even number as in the present embodiment, and the two locking pieces are made into one set, one of the sets and the other pieces of the locking pieces 32 face each other in the radial direction D. It is preferable to dispose each set of locking pieces 32 so as to make them. By setting it as such arrangement | positioning, the latching of the vial 100 by the latching piece 32 can be stabilized more.

[Biasing member 50]
The urging member 50 is configured so that the claw portion 34 of the locking piece 32 enters the annular space 104 defined by the constricted portion 103 of the vial 100, and the claw portion 34 is moved in the direction E opposite to the insertion direction B of the needle-like portion 20. The claw portion 34 is pressed against the wall surface on the top surface 102 side of the constricted portion 103 of the vial 100.

  As shown in FIGS. 1 to 4, the biasing member 50 in the present embodiment is a metal coil spring 50 a as an elastic member. The coil spring 50 a is disposed so as to surround the periphery of the needle-like portion 20 of the piercing member 3, and one end is attached to the flange portion 21. When the needle-like portion 20 is inserted in the insertion direction B with respect to the stopper body 101 of the vial 100, the other end of the coil spring 50 a comes into contact with the top surface 102 of the vial 100. When the needle-like portion 20 is further pushed in the insertion direction B, the coil spring 50a is sandwiched between the flange portion 21 of the piercing member 3 and the top surface 102 of the vial 100 and is elastically deformed. 34 is pressed against the wall surface on the top surface 102 side of the constricted portion 103 of the vial 100, so that the vial adapter 1 and the vial 100 are firmly connected.

  In particular, when a plurality of vials 100, 110 having different outer diameters on the top surface 102 are compared, the thickness T in the insertion direction B of the lid portion 105 including the top surface 102 is also different (see FIGS. 10 and 11). Therefore, when the single vial adapter 1 is configured to be connectable to a plurality of vials 100, 110 having different top diameters, the lid member is provided with the biasing member 50 as in the present embodiment. Regardless of the thickness T of 105, the claw portion 34 of the locking piece 32 is particularly effective because it can always press the desired position on the outer wall of the vial.

  The other end of the coil spring 50a is preferably in contact with a position on the top surface 102 of the vial 100 where the rubber stopper 101a as the stopper 101 is not provided. This is because the rubber plug 101a is elastically deformed by the coil spring 50a and the elastic force by the coil spring 50a may be weakened. Therefore, it is particularly preferable that the other end of the coil spring 50a is in contact with an external region of the top surface 102 of the vial 100 where the rubber stopper 101a as the stopper 101 is not provided.

  In the present embodiment, the coil spring 50a is used as the elastic member. However, the present invention is not limited to this, and for example, a cylindrical rubber having a peripheral surface formed in a bellows shape may be used.

[Movement mechanism of locking member 6]
Up to this point, the components of the vial adapter 1 have been mainly described in detail. Next, a moving mechanism of the locking member 6 that is moved so that the plurality of vials 100 and 110 having different outer diameters of the top surface 102 can be locked by the single vial adapter 1 will be described.

  7 and 8 are exploded perspective views showing a moving mechanism of the locking member 6. Specifically, FIG. 7 shows a plurality of locking pieces 32a to 32d as the locking member 6 in a position that can be attached to the vial 100 whose top surface 102 has an outer diameter of 20 mm. A plurality of locking pieces 32a to 32d are shown in a position that can be attached to the vial 110 whose top surface has an outer diameter of 13 mm. FIG. 9 is a perspective view showing a state in which only the piercing member 3 and the plurality of locking pieces 32a to 32d are taken out from the vial adapter 1, and shows a state in which these members are viewed in the insertion direction B. .

  As shown in FIGS. 7 and 8, a shaft hole 29 is provided at the center of the substantially disc-shaped locking member holder 5, and the protruding portion 22 of the piercing member 3 is fitted into the shaft hole 29. Yes. Thereby, the locking member holder 5 can rotate around the protrusion 22 as a central axis. In other words, when viewed in the insertion direction B of the needle-like portion 20 of the piercing member 3, the locking member holder 5 rotates around the needle-like portion 20 (see FIGS. 1 and 3). .

  Further, as described above, the locking member holder 5 is provided with the guide long hole 30 a as the first guide 30, and the projection 37 provided on the top surface of the held portion 35 of the locking piece 32. It has entered the guide slot 30a. Moreover, the groove | channel 36 (refer FIG. 6) provided in the bottom face in the to-be-held part 35 of the latching piece 32 is fitting with the convex slide rail 31a of the piercing member 3 shown in FIG.

  Therefore, when the locking member holder 5 rotates relative to the connecting member 2, the piercing member 3, and the connecting member 4, the groove 36 of the locking piece 32 has a convex slide rail 31 a extending in the radial direction D. Because of the fitting, the locking piece 32 does not move in the rotation direction G of the locking member holder 5.

  On the other hand, when the locking member holder 5 rotates relative to the connecting member 2, the piercing member 3 and the connecting member 4, the guide long hole 30 a provided in the locking member holder 5 5, since the distance in the radial direction D from the needle-like portion 20 of the piercing member 3 located at the center of rotation gradually increases or decreases as it advances in the rotation direction G of 5, the protrusion fitted in the guide slot 30a. 37 is pushed by the wall surface that defines the guide long hole 30 a, the locking piece 32 moves in the radial direction D on the convex slide rail 31 a provided in the piercing member 3.

  That is, when the locking member holder 5 rotates, the plurality of locking pieces 32 a to 32 d as the locking member 6 are convex as the guide long holes 30 a as the first guide portion 30 and the second guide portion 31. It moves in the radial direction D by being guided by the slide rail 31a.

  Thus, the plurality of locking pieces 32 a to 32 d as the locking member 6 can move in the radial direction D of the locking member holder 5. Therefore, when the vial adapter 1 is connected to each of the vial 100 and the vial 110, the plurality of locking pieces 32a to 32d are substantially circular top surfaces of the vials 100 and 110 provided with the stoppers 101, respectively. The top surface 102 can be moved in the radial direction I (in the present embodiment, the same direction as the radial direction D of the locking member holder 5) according to the outer diameter of the 102, and the plurality of locking pieces 32a to 32d can be moved in the radial direction. By moving to I, the plurality of vials 100 and 110 having different top diameters can be locked only by the plurality of locking pieces 32a to 32d. That is, there is no need to provide different locking members for locking the plurality of vials 100 and 110 having different outer diameters on the top surface 102.

  More specifically, in the present embodiment, the claw portions 34a to 34d of the plurality of locking pieces 32a to 32d move in the radial direction I so that the claw portions 34a to 34d have an outer diameter of the top surface 102. It enters the annular space 104 defined by the constricted portion 103 of each of the plurality of different vials 100 and 110 and comes into contact with the outer wall of each vial 100 and 110. That is, since the plurality of claw portions 34a to 34d sandwich the vials 100 and 110 from the radial direction I, the plurality of claw portions 34a to 34d are inserted in the insertion direction B, the reverse direction E of the insertion direction B, and the radial direction I. The movement of each vial 100, 110 can be restricted, that is, each vial 100, 110 can be locked.

  Furthermore, in this embodiment, since the coil spring 50a as the biasing member 50 described above is provided in addition to the locking piece 32, the claw portion 34 and the coil spring 50a sandwich the lid portion 105 of each vial 100, 110. Therefore, the positions of the vials 100 and 110 in the insertion direction B and the reverse direction E of the insertion direction B can be fixed. That is, the vial adapter 1 of the present embodiment includes the coil spring 50a in addition to the locking piece 32, so that the vials 100 and 110 can be locked more firmly.

  In the present embodiment, the locking member holder 5 is rotated relative to the piercing member 3 to move the locking pieces 32a to 32d in the radial direction I. Since the moving mechanism itself of the locking piece 32 can be reduced in size by using such a rotating mechanism, the entire vial adapter 1 including the moving mechanism can also be reduced in size.

  Here, as shown in FIGS. 7 and 8, the guide long hole 30a in this embodiment is not a hole having a uniform shape in the extending direction, but a part of the wall surface defining the guide long hole 30a. Opposed protrusions 38 are provided as position restricting portions. Specifically, the width W of the guide elongated hole 30 a in the facing protrusion 38 is smaller than the diameter of the substantially cylindrical protrusion 37. By providing the opposing protrusion 38 in the guide long hole 30a in this way, it is possible to restrict the protrusion 37 from freely moving in the guide long hole 30a, so the position of the locking piece 32 in the radial direction D can be determined. It becomes possible to set to a predetermined position. In the present embodiment, when the projection 37 is at one end of the guide long hole 30a, the locking piece 32 becomes the first position where the vial 100 whose top surface 102 has an outer diameter of 20 mm can be locked. When it exists in the other end of the guide long hole 30a, the latching piece 32 becomes a 2nd position which can latch the vial 110 whose outer diameter of the top | upper surface 102 is 13 mm. And the opposing protrusion 38 is a position that restricts the movement of the protrusion 37 to the other end side of the guide long hole 30a when the protrusion 37 of the locking piece 32 is at one end of the guide long hole 30a. When the protrusion 37 of the piece 32 is at the other end of the guide long hole 30a, the protrusion 37 is provided at a position that restricts the movement of the protrusion 37 toward one end of the guide long hole 30a. By providing the opposing protrusion 38 at such a position, the locking piece 32 can be held at a position corresponding to the vial 100 or a position corresponding to the vial 110, and the top surface 102 has a different outer diameter. The vials 100 and 110 can be firmly held by the locking piece 32.

  Furthermore, when the user moves the locking piece 32 to one end or the other end of the guide long hole 30a, it is necessary to rotate the locking member holder 5 by applying a force to overcome the opposing protrusion 38. The user can feel that the protrusion 37 of the locking piece 32 has reached one end or the other end of the guide long hole 30a not only visually but also by tactile sense. In the embodiment, the locking piece 32 is unstable with respect to each of the vials 100 and 110 by misunderstanding that the guide has reached the desired position although it has not reached one end or the other end of the guide long hole 30a. It can suppress staying at a stop position.

  In the present embodiment, the opposing protrusion 38 is used as the position restricting portion. However, the present invention is not limited to this. For example, various configurations such as a configuration in which only one protrusion of the opposing protrusion 38 is used are adopted. Is possible. In the present embodiment, the opposing protrusions 38 are provided at two locations on one end side and the other end side of the guide long hole 30a. For example, between the one end and the other end in the extending direction of the guide long hole 30a. Two pairs of opposed protrusions 38 are further provided to allow the position of the projection 37 to be regulated at a position corresponding to a vial having an outer diameter of the top surface 102 of 15 mm, so that three vials having different outer diameters of the top surface 102 can be stably provided. It is good also as a structure which can be locked to. Of course, you may make it respond | correspond to four or more vials from which the outer diameter of the top | upper surface 102 differs.

  Furthermore, in this embodiment, the guide long hole 30a is used as the first guide part 30 and the convex slide rail 31a is used as the second guide part 31, but the present invention is not limited to this. Any mechanism that moves in the direction D can be used instead of the guide slot 30a or the convex slide rail 31a. For example, the locking member holder 5 may be provided with a protrusion, and the locking member 6 may be provided with a long hole in which the protrusion fits and moves. Similarly, the piercing member 3 may be provided with a groove, and the locking member 6 may be provided with a convex slide rail that fits into the groove.

[Vial adapter connector 70]
So far, the vial adapter 1 which is one embodiment of the present invention has been described. Next, the vial adapter connector 70 as one embodiment of the present invention in which the above-described vial adapter 1 is connected to the vial 100 or the vial 110 will be described. 10 is a cross-sectional view of a vial adapter connector 70a in which the vial adapter 1 is connected to a vial 100 whose top surface 102 has an outer diameter of 20 mm. FIG. 11 is a cross-sectional view of the vial adapter 1 in which the top surface 102 has an outer diameter of 13 mm. It is sectional drawing of the vial adapter connection body 70b connected to the vial 110. FIG. Note that details of the vial adapter 1 are the same as those described above, and a description thereof is omitted here.

  The vial adapter connector 70 a includes a vial 100 having a substantially circular top surface 102 provided with a rubber stopper 101 a as the stopper body 101, and the radial direction of the top surface 102 according to the outer diameter of the top surface 102 of the vial 100. And a vial adapter 1 including a locking member 6 that locks the vial 100 while being in contact with the outer wall of the vial 100 by moving in the radial direction I.

  Specifically, the vial 100 according to the present embodiment includes an accommodating portion 71 that can store a chemical solution, a lid portion 105 having a rubber stopper 101a, a constricted portion 103 positioned between the accommodating portion 71 and the lid portion 105, Is provided.

  The accommodating part 71 has a substantially cylindrical outer shape and defines an internal space 72 that can accommodate a chemical solution.

  The lid portion 105 includes a rubber stopper 101a into which the tip of the needle-like portion 20 of the vial adapter 1 can be inserted from the outside. As shown in FIG. 10, the tip of the needle-like portion 20 passes through the rubber stopper 101a. Enter the internal space 72. The lid 105 also has a substantially cylindrical outer shape.

  The constricted portion 103 is located between the accommodating portion 71 and the lid portion 105 and has an outer shape thinner than the accommodating portion 71 and the lid portion 105. The annular space 104 is defined by the constriction of the constricted portion 103.

  The vial 100 according to the present embodiment includes the above-described storage portion 71, lid portion 105, and constricted portion 103, a chemical solution storage container 73, a rubber plug 101a as the plug body 101, and a rubber plug 101a in the storage container 73. The fixing member 74 is fixed. Specifically, the storage portion 71 and the constricted portion 103 are configured by a storage container 73. In addition, the lid portion 105 is constituted by a storage container 73, a rubber stopper 101 a, and a fixing member 74.

  The fixing member 74 constituting the lid portion 105 is an annular member that divides the annular groove 75 that opens inward, and is arranged so as to cover the opening 75 of the storage container 73 by the side wall of the annular groove 75. The rubber plug 101a is sandwiched between the outer surface of the rubber plug 101a having a circular top surface and the wall surface on the rubber plug 101a side of the outer wall of the storage container 73 forming the constricted portion 103. It is to be fixed.

  Therefore, the substantially circular top surface 102 of the vial 100 in the present embodiment covers the central region of the top surface of the rubber stopper 101a and the top surface of the rubber stopper 101a outside the central region in the radial direction I. And a part of the outer surface of the fixing member 74. As a material of the fixing member 74, for example, a resin material or a metal material can be used.

  The vial adapter 1 allows the claw portion 34 of the plurality of locking pieces 32a to 32d as the locking member 6 to enter the annular space 104 defined by the constricted portion 103 with respect to such a vial 100, and the constricted portion. The vial 100 is locked by making contact with the outer wall of 103 (hanging on the outer wall of the constricted portion 103). As shown in FIG. 10, the locking piece 32 in the present embodiment has a configuration that can move in the radial direction I only to a position where the vial 100 whose top surface 102 has an outer shape of 20 mm can be locked. Therefore, when the vial adapter 1 in the present embodiment is connected to the vial 100, the plurality of locking pieces 32a to 32d are elastically deformed so that the portion of the extending portion 33 is expanded outward in the radial direction I. Thus, the vial adapter 1 is connected to the vial 100.

  However, the locking piece 32 can also be configured to be movable outward in the radial direction I from the position where the vial 100 whose top surface 102 has an outer shape of 20 mm can be locked. It is not limited.

  As shown in FIG. 10, in this embodiment, the lid portion 105 is sandwiched between the claw portion 34 and the coil spring 50 a as the biasing member 50, and the position of the vial adapter 1 with respect to the vial 100 can be fixed. it can.

  Finally, the vial adapter connector 70b will be described. As shown in FIG. 11, the vial adapter connector 70b includes a vial adapter 1 and a vial 110 whose top surface 102 has an outer diameter of 13 mm. Since the vial adapter connector 70b differs from the vial adapter connector 70a described above only in the vial used, the details of this point will be described below, and description of common parts will be omitted here.

  The basic configuration of the vial 110 is the same as that of the vial 100 described above, but the size of each part is different from that of the vial 100. Specifically, the outer diameter in the radial direction I of each part of the vial 110 is smaller than the outer diameter of each corresponding part of the vial 110.

  Therefore, when connecting the vial adapter 1 to the vial 110, the plurality of locking pieces 32a to 32d correspond to an outer diameter larger than the outer diameter of the top surface 102 of the vial 110, as shown by the broken line in FIG. After expanding in the radial direction I to a possible position, the needle-shaped part 20 of the vial adapter 1 is inserted into the rubber stopper 101a, and after the position in the insertion direction B of the vial adapter 1 with respect to the vial 110 reaches the desired position, The vial adapter 1 is connected to the vial 110 by moving the plurality of locking pieces 32a to 32d to the central portion side in the radial direction I to the position indicated by the solid line in FIG.

  More specifically, by moving the plurality of locking pieces 32a to 32d as the locking member 6 in the radial direction I, the constricted portion 103 defines each claw portion 34 of the plurality of locking pieces 32a to 32d. The vial 100 is locked by entering the annular space 104 and making contact with the outer wall of the constricted portion 103 (hanging on the outer wall of the constricted portion 103).

  In the vial adapter 70b, similarly to the above-described vial adapter 70a, the lid portion 105 is sandwiched by the claw portion 34 and the coil spring 50a as the biasing member 50, and the position of the vial adapter 1 with respect to the vial 110 is fixed. be able to. As shown in FIGS. 10 and 11, since the thickness T of the lid 105 is different between the vial 100 and the vial 110, a plurality of vials 100 and 110 having different thicknesses T are provided by providing the biasing member 50. On the other hand, the vial adapter 1 can be stably fixed to the vial.

  Here, in the present embodiment, the vial adapter connector 70a including the vial 100 having the outer diameter of the top surface 102 of 20 mm and the vial adapter connector 70b including the vial 110 having the outer diameter of 13 mm are described. The vial adapter is not limited to these vials, but the top surface 102 has a different outer diameter, for example, a single vial adapter that can accommodate three or four types of vials including vials having outer diameters of 15 mm and 32 mm. It is also possible to use a vial adapter that can be connected to any two of these four types of vials. Note that these outer diameter dimensions are those defined as standards in ISO (International Organization for Standard) 8362-1.

  However, it is of course possible to adopt a vial adapter that is compatible with a plurality of vials having different outer diameters on the top surface 102 that are not manufactured according to these standards.

  The present invention relates to a vial adapter connected to a vial.

1: vial adapter 2: connecting member 3: piercing member 4: connecting member 5: locking member holder 6: locking member 7: connecting port 8: housing 9: slit 10: elastic valve body 11: housing body 12: cap 13: 1st hollow part 14: 2nd hollow part 15: Hollow part 16 of an elastic valve body 16: Bellows part 17: Cylindrical part 18: Inner wall 19 of a cap part: Top surface part 20 of a cylindrical part 20: Needle-like part 21 of a piercing member : Piercing member flange portion 22: piercing member protrusion 23: piercing member hollow portion 24: needle-like base end portion 25: connecting member main body portion 26: connecting member flange portion 27: recessed portion 28 : Connection hollow portion 29: Shaft hole 30: First guide portion 30 a: Guide long hole 31: Second guide portion 31 a: Slide rail 32, 32 a to 32 d: Locking piece 33: Extension portion 34: Claw portion 35: Covered Holding part 36: Groove 37: Protrusion 38: Opposing protrusion 50: Energizing Material 50a: Coil spring 60: Seal member 60a: O-ring 61: Inner surface 62 of the extended portion: Bottom surface 63 of the held portion: Outer surface 64 of the extended portion 65: Top surface 65 of the held portion 65: Cylindrical protrusion 66: Cylindrical Hollow portion 67 of the protruding portion: annular grooves 70, 70a, 70b: vial adapter connector 71: accommodating portion 72: internal space 73: accommodating container 74: fixing member 75: annular groove 100, 110: vial 101: stopper 101a : Rubber stopper 102: top surface 103 of vial: constricted portion 104: annular space 105: lid portion A: insertion direction of insertion member B: insertion direction of needle-like portion C: direction orthogonal to insertion direction of needle-like portion D: Radial direction E of the locking member holder: Reverse direction of needle insertion direction F: Circumferential direction of the locking member holder G: Direction of rotation of the locking member holder H: Direction perpendicular to the top surface of the vial I: Vial Radial direction T on the top surface: Via The thickness of the lid W: guide slot width

Claims (7)

A locking member that contacts the outer wall of the vial having a stopper and locks the vial ;
A piercing member comprising a needle-like portion whose tip is inserted into the stopper of the vial;
And a locking member holder to which the locking member is attached while being supported by the piercing member ,
The locking member holder has a guide portion that guides the locking member to move in the radial direction of the top surface of the substantially circular shape of the vial,
The guide portion has a position restricting portion that restricts a position of the locking member in the radial direction to a predetermined position.
Said locking member, said by movable in the radial direction in accordance with the outer diameter of the top surface, the vial adapter, characterized in that a plurality of different vials of the outer diameter is lockable. The locking member holder is supported by the piercing member so as to be rotatable around the needle-like portion ,
The vial adapter according to claim 1, wherein the locking member moves in the radial direction by rotating the locking member holder with respect to the piercing member. The guide portion is a first guide portion in which a distance from the center in the radial direction gradually increases or decreases as the locking member holder moves in the rotation direction ,
The piercing member includes a second guide portion extending in the radial direction,
3. The locking member according to claim 2, wherein the locking member moves in the radial direction by being guided by the first guide portion and the second guide portion when the locking member holder rotates. The vial adapter as described. While defining the connection port of the insertion member inserted from the outside, including a connection member supported by the piercing member,
The locking member holder is sandwiched between the piercing member and the connecting member in the insertion direction of the needle-like part, and movement of the needle-like part in the insertion direction and in the direction opposite to the insertion direction is restricted. The vial adapter according to claim 2 or 3, wherein   The said locking member is cyclically | annularly arrange | positioned, It is the some locking piece which latches the said vial while contacting with the said outer wall of the said vial, It is any one of Claim 1 thru | or 4 characterized by the above-mentioned. Vial adapter.   The locking piece is defined by an extending portion extending in a direction substantially orthogonal to the top surface of the vial and a constricted portion provided at one end of the extending portion and provided on the outer wall of the vial. The vial adapter according to claim 5, further comprising a claw portion that enters the annular space.   A biasing member that biases the claw part in a direction opposite to the insertion direction of the needle-like part and presses the outer wall of the vial with the claw part entering the annular space is provided. The vial adapter according to claim 6.

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