ITMI920405A0 - Derivati polisaccarici di eparina eparan solfato loro frazioni e frammenti procedimento per la loro preparazione e composizioni farmaceutiche che li contengono - Google Patents

Derivati polisaccarici di eparina eparan solfato loro frazioni e frammenti procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Info

Publication number: ITMI920405A0
Authority: IT; Italy
Prior art keywords: polysacric; eparan; heparin; fractions; fragments
Prior art date: 1992-02-25

Application number

IT92MI405A

Other languages

English (en)

Inventor

Lino Liverani

Giuseppe Mascellani

Pietro Bianchini

Original Assignee

Opocrin

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-25

Filing date

1992-02-25

Publication date

1992-02-25

1992-02-25 Application filed by Opocrin filed Critical Opocrin

1992-02-25 Priority to ITMI920405A priority Critical patent/IT1254216B/it

1992-02-25 Publication of ITMI920405A0 publication Critical patent/ITMI920405A0/it

1993-02-18 Priority to DE69315724T priority patent/DE69315724D1/de

1993-02-18 Priority to EP93102527A priority patent/EP0557887B1/en

1993-02-18 Priority to ES93102527T priority patent/ES2110015T3/es

1993-02-18 Priority to AT93102527T priority patent/ATE161273T1/de

1993-08-25 Publication of ITMI920405A1 publication Critical patent/ITMI920405A1/it

1995-09-14 Application granted granted Critical

1995-09-14 Publication of IT1254216B publication Critical patent/IT1254216B/it

Links

HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical class OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 title 1
WZHCOOQXZCIUNC-UHFFFAOYSA-N cyclandelate Chemical compound C1C(C)(C)CC(C)CC1OC(=O)C(O)C1=CC=CC=C1 WZHCOOQXZCIUNC-UHFFFAOYSA-N 0.000 title 1
239000012634 fragment Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Materials Engineering (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Saccharide Compounds (AREA)

ITMI920405A 1992-02-25 1992-02-25 Derivati polisaccaridici di eparina, eparan solfato, loro frazioni e frammenti, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono IT1254216B (it)

Priority Applications (5)

Application Number	Priority Date	Filing Date	Title
ITMI920405A IT1254216B (it)	1992-02-25	1992-02-25	Derivati polisaccaridici di eparina, eparan solfato, loro frazioni e frammenti, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
DE69315724T DE69315724D1 (de)	1992-02-25	1993-02-18	Polysaccharidderivate von Heparin, Heparansulfate, ihre Fraktionen und Fragmente, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, welche diese enthalten
EP93102527A EP0557887B1 (en)	1992-02-25	1993-02-18	Polysaccharide derivatives of heparin, heparan sulphate, fraction and fragments thereof, process for their preparation and pharmaceutical compositions containing them
ES93102527T ES2110015T3 (es)	1992-02-25	1993-02-18	Derivados de polisacaridos de heparina, sulfato de heparan, sus fracciones y fragmentos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
AT93102527T ATE161273T1 (de)	1992-02-25	1993-02-18	Polysaccharidderivate von heparin, heparansulfate, ihre fraktionen und fragmente, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, welche diese enthalten

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITMI920405A IT1254216B (it)	1992-02-25	1992-02-25	Derivati polisaccaridici di eparina, eparan solfato, loro frazioni e frammenti, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Publications (3)

Publication Number	Publication Date
ITMI920405A0 true ITMI920405A0 (it)	1992-02-25
ITMI920405A1 ITMI920405A1 (it)	1993-08-25
IT1254216B IT1254216B (it)	1995-09-14

Family

ID=11362117

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ITMI920405A IT1254216B (it)	1992-02-25	1992-02-25	Derivati polisaccaridici di eparina, eparan solfato, loro frazioni e frammenti, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Country Status (5)

Country	Link
EP (1)	EP0557887B1 (it)
AT (1)	ATE161273T1 (it)
DE (1)	DE69315724D1 (it)
ES (1)	ES2110015T3 (it)
IT (1)	IT1254216B (it)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5668118A (en) *	1992-07-24	1997-09-16	Cavalier Pharmaceuticals	Method of synthesis of 2-O-desulfated Heparin and use thereof for inhibition of elastase and Cathepspin G
ATE380047T1 (de) *	1992-07-24	2007-12-15	Thomas P Kennedy	Nicht-antikoagulierende desulfatierte heparine als medikamente
US5696100A (en) *	1992-12-22	1997-12-09	Glycomed Incorporated	Method for controlling O-desulfation of heparin and compositions produced thereby
US6127347A (en) *	1994-01-12	2000-10-03	Univ Michigan	Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes
US5583121A (en) *	1994-01-12	1996-12-10	Michigan State University	Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes
US5633233A (en) *	1995-06-07	1997-05-27	Alberta Research Council	Modified kojibiosides analogues
US6217863B1 (en)	1995-10-30	2001-04-17	Massachusetts Institute Of Technology	Rationally designed polysaccharide lyases derived from heparinase I
FR2781485B1 (fr)	1998-07-21	2003-08-08	Denis Barritault	Polymeres biocompatibles leur procede de preparation et les compositions les contenant
US7056504B1 (en)	1998-08-27	2006-06-06	Massachusetts Institute Of Technology	Rationally designed heparinases derived from heparinase I and II
EP1190364A2 (en)	1999-04-23	2002-03-27	Massachusetts Institute Of Technology	System and method for polymer notation
CA2402160C (en)	2000-03-08	2012-02-14	Massachusetts Institute Of Technology	Heparinase iii and uses thereof
EP1319183B1 (en)	2000-09-12	2009-03-25	Massachusetts Institute Of Technology	Methods and products related to low molecular weight heparin
WO2002022122A1 (en) *	2000-09-15	2002-03-21	Novo Nordisk A/S	Use of compounds for the treatment of obesity
AU2440802A (en)	2000-10-18	2002-04-29	Massachusetts Inst Technology	Methods and products related to pulmonary delivery of polysaccharides
WO2003078960A2 (en)	2002-03-11	2003-09-25	Momenta Pharmaceuticals, Inc.	Analysis of sulfated polysaccharides
US9139876B1 (en)	2007-05-03	2015-09-22	Momenta Pharmacueticals, Inc.	Method of analyzing a preparation of a low molecular weight heparin
US8569262B2 (en)	2007-11-02	2013-10-29	Momenta Pharmaceuticals, Inc.	Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
US8592393B2 (en)	2007-11-02	2013-11-26	Momenta Pharmaceuticals, Inc.	Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
US9351992B2 (en)	2007-11-02	2016-05-31	Momenta Pharmaceuticals, Inc.	Non-anticoagulant polysaccharide compositions
CN101584705B (zh) *	2008-05-24	2010-10-27	鲁南制药集团股份有限公司	一种治疗糖尿病及其并发症的药物组合物
CN101584688B (zh) *	2008-05-24	2010-11-10	鲁南制药集团股份有限公司	一种治疗糖尿病及其并发症的药物组合物
EP2558506B1 (en)	2010-04-16	2019-06-26	Momenta Pharmaceuticals, Inc.	Tissue targeting
EP2582355A2 (en)	2010-06-17	2013-04-24	Momenta Pharmaceuticals, Inc.	Methods and compositions for promoting hair growth
US9068957B2 (en)	2011-02-21	2015-06-30	Momenta Pharmaceuticals, Inc.	Evaluating heparin preparations
PL2846809T3 (pl)	2012-05-09	2021-07-26	Cantex Pharmaceuticals, Inc.	Leczenie mielosupresji
WO2014193818A1 (en)	2013-05-28	2014-12-04	Momenta Pharmaceuticals, Inc.	Pharmaceutical compositions
WO2016133910A1 (en)	2015-02-17	2016-08-25	Cantex Pharmaceuticals, Inc.	Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1234508B (it) *	1988-06-10	1992-05-19	Alfa Wassermann Spa	Derivati eparinici e procedimento per la loro preparazione
IT1234826B (it) *	1989-01-30	1992-05-29	Alfa Wassermann Spa	Derivati eparinici e procedimento per la loro preparazione

1992
- 1992-02-25 IT ITMI920405A patent/IT1254216B/it active
1993
- 1993-02-18 AT AT93102527T patent/ATE161273T1/de not_active IP Right Cessation
- 1993-02-18 ES ES93102527T patent/ES2110015T3/es not_active Expired - Lifetime
- 1993-02-18 EP EP93102527A patent/EP0557887B1/en not_active Expired - Lifetime
- 1993-02-18 DE DE69315724T patent/DE69315724D1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0557887A3 (it)	1994-02-09
ES2110015T3 (es)	1998-02-01
ITMI920405A1 (it)	1993-08-25
EP0557887B1 (en)	1997-12-17
IT1254216B (it)	1995-09-14
ATE161273T1 (de)	1998-01-15
DE69315724D1 (de)	1998-01-29
EP0557887A2 (en)	1993-09-01

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