IT8003429A0 - Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica - Google Patents
Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibattericaInfo
- Publication number
- IT8003429A0 IT8003429A0 IT8003429A IT342980A IT8003429A0 IT 8003429 A0 IT8003429 A0 IT 8003429A0 IT 8003429 A IT8003429 A IT 8003429A IT 342980 A IT342980 A IT 342980A IT 8003429 A0 IT8003429 A0 IT 8003429A0
- Authority
- IT
- Italy
- Prior art keywords
- riphamic
- imidazo
- substance
- preparation
- antibacterial action
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (26)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT03429/80A IT1154655B (it) | 1980-05-22 | 1980-05-22 | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
NLAANVRAGE8102290,A NL187022C (nl) | 1980-05-22 | 1981-05-11 | Rifamycine derivaten met anti-bacteriele werking, en dergelijke derivaten bevattend farmaceutisch preparaat. |
US06/262,123 US4341785A (en) | 1980-05-22 | 1981-05-11 | Imidazo-rifamycin derivatives with antibacterial utility |
AU70655/81A AU537093B2 (en) | 1980-05-22 | 1981-05-18 | New imidazo-rifamycin derivatives with antibacterial utility |
AT0222781A AT373599B (de) | 1980-05-22 | 1981-05-19 | Verfahren zur herstellung neuer rifamycinderivate |
LU83376A LU83376A1 (fr) | 1980-05-22 | 1981-05-20 | Nouveaux derives d'imidazo-rifamycine a activite antibacterienne |
GR65010A GR75640B (it) | 1980-05-22 | 1981-05-20 | |
PH25656A PH17207A (en) | 1980-05-22 | 1981-05-20 | New imidazo-rifamycin derivatives with antibacterial utility |
FR8110058A FR2482967A1 (fr) | 1980-05-22 | 1981-05-20 | Nouveaux derives de l'imidazo-rifamycine, leur procede de preparation et leur application en therapeutique |
PT73064A PT73064B (en) | 1980-05-22 | 1981-05-20 | New imidazo-rifamycin derivatives with anti-bacterial utility |
EG280/81A EG14891A (en) | 1980-05-22 | 1981-05-20 | A process for preparation of derivatives of imiadozo-new rifamicyn have process antibacterial utility |
DK224781A DK157876C (da) | 1980-05-22 | 1981-05-21 | Analogifremgangsmaade til fremstilling af imidazo-rifamycin-derivater |
NO811731A NO155622C (no) | 1980-05-22 | 1981-05-21 | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrido- og isokinolin (1[,2[:1,2) imidazo (5,4-c) rifamycin sv og s derivater. |
ES502906A ES502906A0 (es) | 1980-05-22 | 1981-05-21 | Un procedimiento para la preparacion de nuevos derivados de imidazo-rifamicina |
IE1139/81A IE51204B1 (en) | 1980-05-22 | 1981-05-21 | Imidazo-rifamycin derivatives |
BE2/59169A BE888895A (fr) | 1980-05-22 | 1981-05-21 | Nouveaux derives d'imidazo-rifamycine a activite antibacterienne |
FI811565A FI69467C (fi) | 1980-05-22 | 1981-05-21 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara pyrido- och isokinolin(1',2':1,2)imidazo(5,4-c)rifamycin soch sv-derivat |
ZA00813430A ZA813430B (en) | 1980-05-22 | 1981-05-21 | New imidazo-rifamycin derivatives with antibacterial utility |
CA000378015A CA1142518A (en) | 1980-05-22 | 1981-05-21 | Imidazo-rifamycin derivatives with antibacterial utility |
SE8103216A SE453089B (sv) | 1980-05-22 | 1981-05-21 | Imidazo-rifamycinderivat, forfarande for framstellning derav och farmaceutisk komposition |
GB8115790A GB2079270B (en) | 1980-05-22 | 1981-05-22 | Imidazo-rifamycin derivatives |
CH3381/81A CH648037A5 (de) | 1980-05-22 | 1981-05-22 | Imidazo-rifamycin-derivate mit antibakterieller wirksamkeit. |
DE19813120460 DE3120460A1 (de) | 1980-05-22 | 1981-05-22 | Pyridoimidazolorifamycinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
JP7787781A JPS5711987A (en) | 1980-05-22 | 1981-05-22 | Novel imidazo-rifamycin derivative |
AR285424A AR226212A1 (es) | 1980-05-22 | 1981-05-22 | Procedimiento para preparar nuevos derivados de imidazo rifamicina |
PH26842A PH18704A (en) | 1980-05-22 | 1982-02-09 | Method of treatment using inidazo-rifamycin derivatives with antibacterial utility |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT03429/80A IT1154655B (it) | 1980-05-22 | 1980-05-22 | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8003429A0 true IT8003429A0 (it) | 1980-05-22 |
IT1154655B IT1154655B (it) | 1987-01-21 |
Family
ID=11107198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT03429/80A IT1154655B (it) | 1980-05-22 | 1980-05-22 | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
Country Status (25)
Country | Link |
---|---|
US (1) | US4341785A (it) |
JP (1) | JPS5711987A (it) |
AR (1) | AR226212A1 (it) |
AT (1) | AT373599B (it) |
AU (1) | AU537093B2 (it) |
BE (1) | BE888895A (it) |
CA (1) | CA1142518A (it) |
CH (1) | CH648037A5 (it) |
DE (1) | DE3120460A1 (it) |
DK (1) | DK157876C (it) |
EG (1) | EG14891A (it) |
ES (1) | ES502906A0 (it) |
FI (1) | FI69467C (it) |
FR (1) | FR2482967A1 (it) |
GB (1) | GB2079270B (it) |
GR (1) | GR75640B (it) |
IE (1) | IE51204B1 (it) |
IT (1) | IT1154655B (it) |
LU (1) | LU83376A1 (it) |
NL (1) | NL187022C (it) |
NO (1) | NO155622C (it) |
PH (2) | PH17207A (it) |
PT (1) | PT73064B (it) |
SE (1) | SE453089B (it) |
ZA (1) | ZA813430B (it) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1199374B (it) * | 1984-05-15 | 1988-12-30 | Alfa Farmaceutici Spa | Processo per la preparazione di pirido-imidazo-rifamicine |
IT1264494B1 (it) * | 1993-03-23 | 1996-09-24 | Alfa Wassermann Spa | Uso di rifaximin e di formulazioni che la contengono nel trattamento delle dispepsie gastriche originate da helicobacter |
US6861053B1 (en) * | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
US5981522A (en) * | 1995-09-01 | 1999-11-09 | Kaneka Corporation | Treatment of disease caused by infection of Helicobacter |
KR100407851B1 (ko) * | 1997-02-28 | 2004-04-29 | 가네가후치 가가쿠고교 가부시키가이샤 | 헬리코박터의감염에기인하는질환치료제 |
WO2003045319A2 (en) * | 2001-11-21 | 2003-06-05 | Activbiotics, Inc. | Targeted therapeutics and uses thereof |
WO2003051299A2 (en) * | 2001-12-13 | 2003-06-26 | Activbiotics, Inc. | Sulfhydryl rifamycins and uses thereof |
AU2003276254A1 (en) * | 2002-11-05 | 2004-06-07 | Piero Chiarelli | Controlled and continued delivery of rifaximin and/or other substances |
US7820652B2 (en) * | 2003-09-24 | 2010-10-26 | Activbiotics Pharma, Llc | Regimen for the administration of rifamycin-class antibiotics |
ITMI20032144A1 (it) * | 2003-11-07 | 2005-05-08 | Alfa Wassermann Spa | Forme polimorfe di rifaximina, processi per ottenerle e |
US7923553B2 (en) * | 2003-11-07 | 2011-04-12 | Alfa Wassermann, S.P.A. | Processes for the production of polymorphic forms of rifaximin |
US7902206B2 (en) * | 2003-11-07 | 2011-03-08 | Alfa Wassermann, S.P.A. | Polymorphic forms α, β and γ of rifaximin |
US20080262024A1 (en) * | 2003-11-07 | 2008-10-23 | Giuseppe Claudio Viscomi | Rifaximin compositions and method of use |
US7906542B2 (en) * | 2004-11-04 | 2011-03-15 | Alfa Wassermann, S.P.A. | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin |
US7256187B2 (en) * | 2004-03-10 | 2007-08-14 | Cumbre Pharmaceuticals Inc. | Rifamycin C-11 oxime derivatives effective against drug-resistant microbes |
US7265107B2 (en) * | 2004-03-10 | 2007-09-04 | Cumbre Pharmaceuticals Inc. | Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes |
US7202246B2 (en) * | 2004-06-09 | 2007-04-10 | Cumbre Pharmaceuticals Inc. | Spiro-rifamycin derivatives targeting RNA polymerase |
US20060210492A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Use of rifaximin for treatment and prevention of periodontal conditions |
US20060210483A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections |
US8003118B2 (en) * | 2005-03-02 | 2011-08-23 | Kodsi Robert E | Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis |
SI1698630T1 (sl) | 2005-03-03 | 2015-01-30 | Alfa Wassermann S.P.A. | Nove polimorfne oblike rifaksimina, postopki za njihovo pripravo in njihova uporaba v medicinskih pripravkih |
ITBO20050123A1 (it) * | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
CN101282981B (zh) | 2005-08-11 | 2012-09-26 | 塔甘塔治疗公司 | 膦酸化利福霉素及其在预防和治疗骨和关节感染中的用途 |
CN101594885B (zh) | 2006-03-09 | 2017-07-18 | 萨利克斯药品公司 | 利福昔明抗直肠功能障碍制剂 |
PT2054066E (pt) | 2006-08-02 | 2015-07-16 | Salix Pharmaceuticals Inc | Métodos para tratamento de enterite por radiação |
ITMI20061692A1 (it) | 2006-09-05 | 2008-03-06 | Alfa Wassermann Spa | Uso di polioli per ottenere forme polimorfe stabili di rifaximina |
KR101667534B1 (ko) * | 2006-09-22 | 2016-10-19 | 씨아이피엘에이 엘티디. | 리팍시민 |
US20080161337A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Chronic Prostatitis |
US20080159987A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Restless Legs Syndrome |
ITMI20071241A1 (it) * | 2007-06-20 | 2008-12-21 | Solmag S P A | Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta |
ES2905795T3 (es) | 2007-07-06 | 2022-04-12 | Lupin Ltd | Composiciones farmacéuticas de rifaximina |
WO2009008005A1 (en) | 2007-07-06 | 2009-01-15 | Lupin Limited | Pharmaceutical compositions of rifaximin |
US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
US8486956B2 (en) | 2008-02-25 | 2013-07-16 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
UA101829C2 (uk) | 2008-02-25 | 2013-05-13 | Саликс Фармасьютикалз, Лтд. | ФОРМА η РИФАКСИМІНУ І ЇЇ ЗАСТОСУВАННЯ В ТЕРАПЕВТИЧНІЙ ПРАКТИЦІ |
EP2252148B1 (en) | 2008-02-26 | 2019-03-20 | Salix Pharmaceuticals, Ltd. | Methods for treating irritable bowel syndrome |
US11779571B2 (en) | 2008-02-26 | 2023-10-10 | Salix Pharmaceuticals, Inc. | Methods for treating irritable bowel syndrome (IBS) |
WO2009137672A1 (en) | 2008-05-07 | 2009-11-12 | Salix Pharmaceuticals, Ltd. | Methods of treating bowel disease by administering a bowel cleanser and an antibiotic |
WO2010019511A2 (en) | 2008-08-13 | 2010-02-18 | Targanta Therapeutics Corp. | Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections |
RU2011116400A (ru) | 2008-09-26 | 2012-11-10 | Аска Фармасьютикал Ко., Лтд. (Jp) | Средство для предотвращения и/или лечения функционального расстройства желудочно-кишечного тракта |
ES2770308T3 (es) | 2008-10-02 | 2020-07-01 | Salix Pharmaceuticals Ltd | Procedimientos de tratamiento de encefalopatía hepática |
JP5756020B2 (ja) | 2008-12-10 | 2015-07-29 | シプラ・リミテッド | リファキシミン複合体 |
IT1397617B1 (it) * | 2009-04-20 | 2013-01-18 | Alfa Wassermann Spa | Nuovi derivati della rifamicina |
NZ596851A (en) | 2009-06-02 | 2013-10-25 | Salix Pharmaceuticals Ltd | Methods of treating hepatic encephalopathy |
EP2475392A4 (en) | 2009-09-13 | 2013-01-09 | Salix Pharmaceuticals Ltd | METHOD FOR TREATING IRRITATION SYNDROME |
CN113274355B (zh) | 2009-10-27 | 2023-05-30 | 鲁平有限公司 | 利福昔明固体分散体 |
RU2012126084A (ru) | 2009-11-23 | 2013-12-27 | Сипла Лимитед | Пенная композиция для местного применения |
WO2011080691A1 (en) | 2009-12-28 | 2011-07-07 | Silvio Massimo Lavagna | Method for the production of amorphous rifaximin |
EP3650022A1 (en) | 2010-02-18 | 2020-05-13 | Salix Pharmaceuticals, Ltd. | Methods for treating rifampin resistant clostridium difficilis infections |
IT1398550B1 (it) | 2010-03-05 | 2013-03-01 | Alfa Wassermann Spa | Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo |
JP6092629B2 (ja) | 2010-03-10 | 2017-03-08 | ルピン・リミテッドLupin Limited | リファキシミン使用準備済懸濁液 |
EP2593463B1 (en) | 2010-07-12 | 2020-05-06 | Salix Pharmaceuticals, Inc. | Formulations of rifaximin and uses thereof |
WO2012035544A2 (en) | 2010-09-13 | 2012-03-22 | Sequent Scientific Ltd. | A novel polymorphic form of rifaximin and process for its preparation |
SG192122A1 (en) | 2011-02-11 | 2013-08-30 | Salix Pharmaceuticals Ltd | Forms of rifaximin and uses thereof |
CA2834829A1 (en) | 2011-05-02 | 2012-11-08 | Ranbaxy Laboratories Limited | Rifaximin dimethylformamide solvate |
ITMI20110890A1 (it) * | 2011-05-19 | 2012-11-20 | A M S A Anonima Materie Sint & Affini S P A | Polimorfo di rifaximina e processo per la sua preparazione |
ITBO20110461A1 (it) | 2011-07-29 | 2013-01-30 | Alfa Wassermann Spa | Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali. |
RU2496475C2 (ru) | 2011-10-26 | 2013-10-27 | Александр Васильевич Иващенко | Фармацевтическая композиция и набор для лечения бактериальных инфекций |
PL2773205T3 (pl) | 2011-11-02 | 2024-09-02 | Salix Pharmaceuticals, Inc. | Ryfaksymina w leczeniu ustępującej biegunki z przewagą zespołu jelita drażliwego |
EP2807148A4 (en) * | 2012-01-25 | 2015-04-08 | Salix Pharmaceuticals Ltd | RIFAXIMIN DERIVATIVE AND USES THEREOF |
ITBO20120368A1 (it) | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
WO2014091432A1 (en) | 2012-12-12 | 2014-06-19 | Ranbaxy Laboratories Limited | Pharmaceutical compositions of rifaximin |
EP2968283A1 (en) | 2013-03-15 | 2016-01-20 | ALFA WASSERMANN S.p.A. | Rifaximin for use in the treating of vaginal infections. |
JP2016516988A (ja) | 2013-03-15 | 2016-06-09 | アルファ ワッセルマン ソシエタ ペル アチオニAlfa Wassermann S.P.A. | 膣感染症を診断するための方法 |
NZ713440A (en) | 2013-04-12 | 2019-02-22 | Alfasigma Spa | Nsaid administration and related compositions, methods and systems. |
US9018225B1 (en) | 2013-07-26 | 2015-04-28 | Novel Laboratories | Rifaximin crystalline forms and methods of preparation thereof |
ES2621557T3 (es) | 2014-03-31 | 2017-07-04 | Euticals S.P.A. | Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas |
CA2946101A1 (en) * | 2014-04-19 | 2015-10-22 | Granules India Limited | An improved process for the preparation of rifamycin derivatives |
JP6693946B2 (ja) | 2014-05-04 | 2020-05-13 | サリックス ファーマスーティカルズ,インコーポレーテッド | Ibs微生物叢及びその使用 |
PL3546464T3 (pl) | 2014-05-12 | 2020-11-02 | Alfasigma S.P.A. | Sposób wytwarzania i zastosowanie postaci krystalicznej Tau rifaksyminy solwatowanej z DEGME |
EP2982764A1 (en) | 2014-08-05 | 2016-02-10 | ALFA WASSERMANN S.p.A. | Identification of vaginal bacteria |
US9988398B2 (en) | 2016-06-07 | 2018-06-05 | Cadila Healthcare Limited | Crystalline form of rifaximin and process for its preparation |
CN110072525B (zh) | 2016-09-30 | 2022-12-02 | 萨利克斯药品公司 | 利福昔明的固态分散形式 |
CN110770244A (zh) * | 2017-06-26 | 2020-02-07 | 倍尔福股份公司 | 吡啶并咪唑利福霉素衍生物的抗菌剂 |
IT201700091912A1 (it) * | 2017-08-08 | 2019-02-08 | Biofer Spa | Nuove pirido-imidazo rifamicine |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE273377C (it) * | ||||
AT273377B (de) * | 1967-03-01 | 1969-08-11 | Lepetit Spa | Verfahren zur Herstellung von neuen Rifamycinen |
AT344898B (de) * | 1975-06-13 | 1978-08-10 | Archifar Ind Chim Trentino | Verfahren zur herstellung neuer rifamycin-verbindungen |
DK345977A (da) * | 1976-09-30 | 1978-03-31 | Archifar Ind Chim Trentino | G rifamycinforbindelser og fremgangsmaade til deres fremstillin |
CH629212A5 (it) * | 1976-10-18 | 1982-04-15 | Erba Farmitalia | Procedimento per la preparazione di composti di rifamicina. |
CH633014A5 (en) * | 1978-06-09 | 1982-11-15 | Erba Farmitalia | Rifamycin compounds |
-
1980
- 1980-05-22 IT IT03429/80A patent/IT1154655B/it active Protection Beyond IP Right Term
-
1981
- 1981-05-11 US US06/262,123 patent/US4341785A/en not_active Expired - Lifetime
- 1981-05-11 NL NLAANVRAGE8102290,A patent/NL187022C/xx not_active IP Right Cessation
- 1981-05-18 AU AU70655/81A patent/AU537093B2/en not_active Expired
- 1981-05-19 AT AT0222781A patent/AT373599B/de not_active IP Right Cessation
- 1981-05-20 GR GR65010A patent/GR75640B/el unknown
- 1981-05-20 FR FR8110058A patent/FR2482967A1/fr active Granted
- 1981-05-20 PT PT73064A patent/PT73064B/pt unknown
- 1981-05-20 LU LU83376A patent/LU83376A1/fr unknown
- 1981-05-20 EG EG280/81A patent/EG14891A/xx active
- 1981-05-20 PH PH25656A patent/PH17207A/en unknown
- 1981-05-21 IE IE1139/81A patent/IE51204B1/en not_active IP Right Cessation
- 1981-05-21 BE BE2/59169A patent/BE888895A/fr not_active IP Right Cessation
- 1981-05-21 ES ES502906A patent/ES502906A0/es active Granted
- 1981-05-21 NO NO811731A patent/NO155622C/no unknown
- 1981-05-21 FI FI811565A patent/FI69467C/fi not_active IP Right Cessation
- 1981-05-21 SE SE8103216A patent/SE453089B/sv not_active IP Right Cessation
- 1981-05-21 DK DK224781A patent/DK157876C/da active
- 1981-05-21 ZA ZA00813430A patent/ZA813430B/xx unknown
- 1981-05-21 CA CA000378015A patent/CA1142518A/en not_active Expired
- 1981-05-22 GB GB8115790A patent/GB2079270B/en not_active Expired
- 1981-05-22 AR AR285424A patent/AR226212A1/es active
- 1981-05-22 DE DE19813120460 patent/DE3120460A1/de active Granted
- 1981-05-22 CH CH3381/81A patent/CH648037A5/de not_active IP Right Cessation
- 1981-05-22 JP JP7787781A patent/JPS5711987A/ja active Granted
-
1982
- 1982-02-09 PH PH26842A patent/PH18704A/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IT8003429A0 (it) | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica | |
IT1141057B (it) | Derivati di deformiltilosina e loro preparazione | |
IT8222769A0 (it) | Composti tetrakisazo derivati e procedimenti per la loro preparazione ed uso | |
IT1130489B (it) | Derivati chinonici particolarmente utili come medianti e procedimento per la loro preparazione | |
IT1123120B (it) | Cefem derivati e procedimento per la loro preparazione | |
IT1164735B (it) | Derivati adenosinici e procedimento per la loro preparazione | |
IT1164076B (it) | Composti farmaceutici ad azione antiulcera e procedimento per la loro preparazione | |
IT7969010A0 (it) | Derivati di benzotiepinici e procedimento per la loro preparazione | |
IT1165368B (it) | Nuovi cefem derivati ad azione antimicrobica e procedimento per la loro preparazione | |
IT1147741B (it) | Derivati di idrossiammino eburnano e procedimento per la loro preparazione | |
IT1132403B (it) | Derivati di alovincamone e procedimento per la loro preparazione | |
IT1094902B (it) | Composti bis-benzimidazolilici sostituiti,loro preparazione e loro uso | |
IT1143701B (it) | Derivati aril-idrazonici,loro uso come pesticidi e loro preparazione | |
IT1135629B (it) | N-imidzolil derivati di 1-cromano e procedimento per la loro preparazione | |
IT1132404B (it) | Derivati di 10-alo-e-omoeburnano e procedimento per la loro preparazione | |
IT1127336B (it) | Derivati della cefalosporina loro preparazione e loro impiego | |
IT1106130B (it) | Derivati di 24-deidrovitamina d3 e loro preparazione | |
IT1169903B (it) | Derivati epossicarbaciclinici, loro preparazione e loro uso | |
IT1212412B (it) | Derivati della benzo-as-triazina e procedimento per la loro preparazione. | |
IT1174735B (it) | Derivati di tunicamina di attivita antibatterica e loro metodo di preparazione | |
IT8303354A0 (it) | Derivati carbomoil-rifamicinici,metodi per la loro preparazione e loro uso come sostanze ad azione antibatterica | |
IT8203626A0 (it) | Nuovi derivati imidazorifamicinici, metodi per la loro preparazione e loro uso come sostanze ad azione antibatterica | |
IT8203360A0 (it) | Nuovi derivati carbamoilrifamicinici, metodi per la loro preparazione e loro uso come sostanze ad azione antibatterica | |
IT1150799B (it) | Cefem derivati e procedimento per la loro preparazione | |
IT8119566A0 (it) | Derivati della prostaciclina,loro preparazione e impiego |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ITCP | Complementary protection certificate |
Free format text: CCP 46 |
|
MEDD | Supplementary protection certificate for pharmaceutical products: granted |
Free format text: CCP 46, 19920304; ALFA WASSERMANN S.P.A. |
|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970423 |