IN2013MU01313A - - Google Patents

Info

Publication number
IN2013MU01313A
IN2013MU01313A IN1313MU2013A IN2013MU01313A IN 2013MU01313 A IN2013MU01313 A IN 2013MU01313A IN 1313MU2013 A IN1313MU2013 A IN 1313MU2013A IN 2013MU01313 A IN2013MU01313 A IN 2013MU01313A
Authority
IN
India
Prior art keywords
mixture
water
present
purification
norethindrone
Prior art date
Application number
Inventor
Amit Madanrao Agarkar
Himanshu Madhav Godbole
Girij Pal Singh
Original Assignee
Lupin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lupin Ltd filed Critical Lupin Ltd
Priority to PCT/IB2014/059994 priority Critical patent/WO2014162230A1/en
Priority to IN1313MU2013 priority patent/IN2013MU01313A/en
Publication of IN2013MU01313A publication Critical patent/IN2013MU01313A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Indole Compounds (AREA)

Abstract

The present invention provides a process forthe purification of norethindrone (I) from mixture of dimethyl formamide-water. The present invention further provides two processes for the purification of norethindrone acetate (II) from mixture of dichloromethane-n-heptane (Process A) and from mixture of methanol-water (Process B).
IN1313MU2013 2013-04-04 2014-03-20 IN2013MU01313A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/IB2014/059994 WO2014162230A1 (en) 2013-04-04 2014-03-20 Process for the purification of norethindrone and norethindrone acetate
IN1313MU2013 IN2013MU01313A (en) 2013-04-04 2014-03-20

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1313MU2013 IN2013MU01313A (en) 2013-04-04 2014-03-20

Publications (1)

Publication Number Publication Date
IN2013MU01313A true IN2013MU01313A (en) 2015-04-10

Family

ID=50390155

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1313MU2013 IN2013MU01313A (en) 2013-04-04 2014-03-20

Country Status (2)

Country Link
IN (1) IN2013MU01313A (en)
WO (1) WO2014162230A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111875656A (en) * 2020-06-23 2020-11-03 浙江神洲药业有限公司 Preparation method of norethindrone acetate

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2744122A (en) 1951-11-22 1956-05-01 Syntex Sa delta 4-19-nor-17alpha-ethinylandrosten-17beta-ol-3-one and process
US2964537A (en) 1956-06-16 1960-12-13 Schering Ag Therapeutically valuable carboxylic acid esters of 17-alkyl-19-nor-testosterone
US3409643A (en) 1966-03-11 1968-11-05 Schering Corp Process for the preparation of 17alpha-alkynl-17beta-alkanoyloxy steroids of the androstane and estrane series
US3408371A (en) 1966-06-16 1968-10-29 Syntex Corp Esterification of 17alpha-ethinyl-17beta-hydroxy steroids
AT314098B (en) 1970-06-13 1974-03-25 Schering Ag Process for the ethynylation of 17-keto steroids
GB1399162A (en) * 1972-06-29 1975-06-25 Schering Ag 6-keto-delta1,3,5-10-steroids and process for the manufacture of 6-keto-delta1,3,5-10-steroids
DK136729C (en) * 1974-10-18 1978-05-01 Schering Ag ANALOGICAL PROCEDURE FOR THE PREPARATION OF 1ALFA, 17BETA-DIHYDROXY-17BETA-ALKYNYL-4-OESTREN-3-ONERS
US4244949A (en) * 1978-04-06 1981-01-13 The Population Council, Inc. Manufacture of long term contraceptive implant
DD295637A5 (en) * 1981-09-07 1991-11-07 Jenapharm Gmbh Jena,De PROCESS FOR CLEANING STEROIDS
US4826689A (en) * 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds

Also Published As

Publication number Publication date
WO2014162230A1 (en) 2014-10-09

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IN2013MU01313A (en)