IL117035A - Paroxetine hydrochloride anhydrate substantially free of bound propan-2-ol processes for its preparation and pharmaceutical compositions containing it - Google Patents

Paroxetine hydrochloride anhydrate substantially free of bound propan-2-ol processes for its preparation and pharmaceutical compositions containing it

Info

Publication number
IL117035A
IL117035A IL11703596A IL11703596A IL117035A IL 117035 A IL117035 A IL 117035A IL 11703596 A IL11703596 A IL 11703596A IL 11703596 A IL11703596 A IL 11703596A IL 117035 A IL117035 A IL 117035A
Authority
IL
Israel
Prior art keywords
processes
preparation
pharmaceutical compositions
substantially free
compositions containing
Prior art date
Application number
IL11703596A
Other languages
English (en)
Other versions
IL117035A0 (en
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27267578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL117035(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9502297.6A external-priority patent/GB9502297D0/en
Priority claimed from GBGB9503112.6A external-priority patent/GB9503112D0/en
Priority claimed from GBGB9509807.5A external-priority patent/GB9509807D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of IL117035A0 publication Critical patent/IL117035A0/xx
Publication of IL117035A publication Critical patent/IL117035A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL11703596A 1995-02-06 1996-02-05 Paroxetine hydrochloride anhydrate substantially free of bound propan-2-ol processes for its preparation and pharmaceutical compositions containing it IL117035A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9502297.6A GB9502297D0 (en) 1995-02-06 1995-02-06 Novel compound
GBGB9503112.6A GB9503112D0 (en) 1995-02-17 1995-02-17 Novel compound
GBGB9509807.5A GB9509807D0 (en) 1995-05-15 1995-05-15 Novel compounds

Publications (2)

Publication Number Publication Date
IL117035A0 IL117035A0 (en) 1996-09-12
IL117035A true IL117035A (en) 2000-02-29

Family

ID=27267578

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11703596A IL117035A (en) 1995-02-06 1996-02-05 Paroxetine hydrochloride anhydrate substantially free of bound propan-2-ol processes for its preparation and pharmaceutical compositions containing it

Country Status (47)

Country Link
EP (3) EP0808314B1 (fi)
JP (2) JP2915338B2 (fi)
KR (1) KR100289885B1 (fi)
CN (3) CN1289496C (fi)
AR (2) AR001982A1 (fi)
AT (1) AT407528B (fi)
AU (2) AU701518C (fi)
BE (1) BE1009112A3 (fi)
BG (1) BG62967B1 (fi)
BR (1) BR9600534A (fi)
CA (4) CA2210023C (fi)
CH (3) CH688353A5 (fi)
CZ (1) CZ297171B6 (fi)
DE (3) DE69631298T2 (fi)
DK (2) DK11996A (fi)
DZ (1) DZ1989A1 (fi)
ES (1) ES2114471B1 (fi)
FI (3) FI111544B (fi)
FR (1) FR2730232B1 (fi)
GR (1) GR1002466B (fi)
HK (1) HK59397A (fi)
HU (1) HUP9600255A1 (fi)
IE (1) IE80500B1 (fi)
IL (1) IL117035A (fi)
IT (1) IT1289532B1 (fi)
LU (1) LU88711A1 (fi)
LV (1) LV11618B (fi)
MA (1) MA23802A1 (fi)
MC (1) MC2411A1 (fi)
MX (1) MX9600484A (fi)
MY (1) MY132529A (fi)
NL (1) NL1002248C2 (fi)
NO (3) NO301009B1 (fi)
NZ (1) NZ280943A (fi)
OA (1) OA10261A (fi)
PL (1) PL189247B1 (fi)
PT (1) PT101827B (fi)
RO (1) RO112426B1 (fi)
RU (1) RU2125052C1 (fi)
SE (1) SE521084C2 (fi)
SG (1) SG43787A1 (fi)
SI (2) SI21923B (fi)
SK (1) SK283608B6 (fi)
TR (1) TR199600096A2 (fi)
TW (1) TW503238B (fi)
UA (1) UA49796C2 (fi)
WO (1) WO1996024595A1 (fi)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3882224B2 (ja) 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
DE69739561D1 (de) 1996-06-13 2009-10-15 Sumitomo Chemical Co Piperidin Derivative als Zwischenprodukte zur Herstellung von Paroxetine und Verfahren zu ihrer Herstellung
WO1998002556A2 (en) * 1996-07-15 1998-01-22 Smithkline Beecham Plc Screening for and use of an esterase for a stereospecific resolution
US5672612A (en) * 1996-09-09 1997-09-30 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
US6638948B1 (en) 1996-09-09 2003-10-28 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
CA2193939C (en) * 1996-12-24 2002-02-12 K.S. Keshava Murthy Useful form of anhydrous paroxetine hydrochloride
KR100543614B1 (ko) * 1997-06-10 2006-01-20 신톤 비.브이. 4-페닐피페리딘 화합물
ES2150808T3 (es) * 1997-08-08 2000-12-01 Aventis Pharma Gmbh Forma cristalina de (4-trifluorometil)-anilida de acido 5-metilisoxazol-4-carboxilico.
GB9726907D0 (en) * 1997-12-19 1998-02-18 Smithkline Beecham Plc Novel compounds
CA2323896A1 (en) * 1998-03-16 1999-09-23 Andrew Simon Craig Crystalline form of paroxetine
GB9806312D0 (en) * 1998-03-24 1998-05-20 Smithkline Beecham Plc Novel formulations
US6699882B2 (en) 1998-03-24 2004-03-02 Smithkline Beecham P.L.C. Paroxetine compositions
AU2003200534B2 (en) * 1998-03-24 2004-12-02 Smithkline Beecham Plc Paroxetine compositions
JP3796351B2 (ja) * 1998-04-13 2006-07-12 住友化学株式会社 パロキセチン塩酸塩無水和物の乾燥方法
GB9812941D0 (en) * 1998-06-16 1998-08-12 Smithkline Beecham Plc Method of treatment
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
ES2138937B1 (es) 1998-07-07 2000-10-01 Medichem Sa Polimorfo de maleato de paroxetina y formulaciones farmaceuticas que lo contienen.
PT1100796E (pt) * 1998-08-07 2003-09-30 Smithkline Beecham Plc Processo para a preparacao de um cloridrato de paroxetina na forma anidra nao cristalina
GB9824298D0 (en) * 1998-11-05 1998-12-30 Smithkline Beecham Plc Novel process
GB9826175D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826176D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826242D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
ES2211232T3 (es) * 1998-11-30 2004-07-01 Smithkline Beecham Plc Solvatos mixtos de paroxetina-propan-2-ol.
GB9826178D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826180D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826171D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel compounds
GB9828767D0 (en) * 1998-12-29 1999-02-17 Smithkline Beecham Plc Novel process
WO2000054775A1 (de) * 1999-03-12 2000-09-21 Basf Ag Stabile pharmazeutische anwendungsform für paroxetin-anhydrat
GB9914585D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9914583D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923446D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923445D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
HU226912B1 (en) * 2000-04-07 2010-03-01 Richter Gedeon Nyrt New paroxetin salt and medicament containing it
JPWO2002022609A1 (ja) * 2000-09-14 2004-01-22 旭硝子株式会社 実質的に有機溶媒を含まないパロキセチン塩類の製造方法
AU2002259114A1 (en) * 2002-02-22 2003-09-09 Teva Pharmaceutical Industries Ltd. Preparation of paroxetine involving novel intermediates
WO2007062147A1 (en) * 2005-11-22 2007-05-31 Teva Pharmaceutical Industries Ltd. Crystal forms of cinacalcet hci and processes for their preparation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
GB8430581D0 (en) * 1984-12-04 1985-01-09 Ferrosan As Treatment
DE3688827T2 (de) * 1985-10-25 1994-03-31 Beecham Group Plc Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel.
GB8626936D0 (en) * 1986-11-11 1986-12-10 Ferrosan As Treatment
DK715988D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Etherifikation og dealkylering af piperidin-derivater samt intermediater
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
KR930702000A (ko) * 1990-11-24 1993-09-08 데이빗 로버츠 노년기 치매, 식용항진, 편두통, 또는 식용불량의 치료를 위한 파로세틴의 사용
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation

Also Published As

Publication number Publication date
ES2114471B1 (es) 1999-08-16
CA2210022A1 (en) 1996-08-07
NO20015070D0 (no) 2001-10-18
TW503238B (en) 2002-09-21
JPH11228571A (ja) 1999-08-24
MX9600484A (es) 1997-01-31
DE69621777D1 (de) 2002-07-18
MA23802A1 (fr) 1996-10-01
NO960472D0 (no) 1996-02-05
HUP9600255A1 (en) 1997-03-28
DE19603797A1 (de) 1996-08-14
FI111544B (fi) 2003-08-15
NO20015070L (no) 1996-08-07
DK200100223A (fi) 2001-02-12
FR2730232A1 (fr) 1996-08-09
FI960519A (fi) 1996-08-07
CA2210023C (en) 1999-02-09
GR1002466B (el) 1996-11-06
DE69631298D1 (de) 2004-02-12
LV11618A (lv) 1996-12-20
SI9600036B (sl) 2006-12-31
NO311519B1 (no) 2001-12-03
CZ32096A3 (en) 1996-08-14
AR036856A2 (es) 2004-10-06
NL1002248A1 (nl) 1996-08-06
EP1378508A1 (en) 2004-01-07
ITMI960203A1 (it) 1997-08-05
PT101827B (pt) 1997-08-29
MC2411A1 (fr) 1996-12-02
MY132529A (en) 2007-10-31
KR960031409A (ko) 1996-09-17
CA2168829C (en) 1997-12-16
RU2125052C1 (ru) 1999-01-20
ES2114471A1 (es) 1998-05-16
AR001982A1 (es) 1998-01-07
CN1636993A (zh) 2005-07-13
DK11996A (da) 1996-08-07
DZ1989A1 (fr) 2002-10-15
CN1143643A (zh) 1997-02-26
FI960519A0 (fi) 1996-02-05
IT1289532B1 (it) 1998-10-15
HU9600255D0 (en) 1996-03-28
SG43787A1 (en) 1997-11-14
CN1090187C (zh) 2002-09-04
NO301009B1 (no) 1997-09-01
FI20030370A (fi) 2003-03-12
CH689229A5 (de) 1998-12-31
FI20030162A (fi) 2003-02-03
EP1136490B1 (en) 2004-01-07
CH688353A5 (de) 1997-08-15
DE69631298T2 (de) 2004-11-18
DE19603797C2 (de) 1998-11-12
HK59397A (en) 1997-05-16
NO970939L (no) 1996-08-07
AU701518B2 (en) 1999-01-28
RO112426B1 (ro) 1997-09-30
NO301009B3 (fi) 2003-01-06
SI21923A (sl) 2006-06-30
CN1310180A (zh) 2001-08-29
DE69621777T2 (de) 2003-01-02
SE9600406L (sv) 1996-08-07
MX198371B (fi) 2000-08-29
ATA21096A (de) 2000-08-15
BE1009112A3 (fr) 1996-11-05
IL117035A0 (en) 1996-09-12
NZ280943A (en) 1997-01-29
LV11618B (en) 1997-04-20
IE80500B1 (en) 1998-08-12
SK14396A3 (en) 1996-11-06
EP1136490A1 (en) 2001-09-26
PL312646A1 (en) 1996-08-19
CA2210022C (en) 2005-09-13
CN1216055C (zh) 2005-08-24
BR9600534A (pt) 1997-05-13
FR2730232B1 (fr) 1997-08-01
CA2211522C (en) 1999-12-07
NO960472L (no) 1996-08-07
WO1996024595A1 (en) 1996-08-15
PT101827A (pt) 1996-09-30
AU4332896A (en) 1996-08-15
NO970939D0 (no) 1997-02-28
PL189247B1 (pl) 2005-07-29
IE960104A1 (en) 1996-08-07
JP2915338B2 (ja) 1999-07-05
SE521084C2 (sv) 2003-09-30
UA49796C2 (uk) 2002-10-15
BG100333A (bg) 1996-08-30
CA2210023A1 (en) 1996-08-07
CZ297171B6 (cs) 2006-09-13
BG62967B1 (bg) 2000-12-29
OA10261A (en) 1997-09-19
TR199600096A2 (tr) 1996-08-21
CA2168829A1 (en) 1996-08-07
JPH08245620A (ja) 1996-09-24
EP0808314B1 (en) 2002-06-12
ITMI960203A0 (fi) 1996-02-05
EP0808314A1 (en) 1997-11-26
AT407528B (de) 2001-04-25
SE9600406D0 (sv) 1996-02-05
NL1002248C2 (nl) 1996-09-11
SI21923B (sl) 2006-12-31
SI9600036A (en) 1996-10-31
SK283608B6 (sk) 2003-10-07
AU4786496A (en) 1996-08-27
CH689804A5 (de) 1999-11-30
AU701518C (en) 2006-12-07
LU88711A1 (fr) 1996-08-23
CN1289496C (zh) 2006-12-13
CA2211522A1 (en) 1996-08-07
KR100289885B1 (ko) 2001-05-15

Similar Documents

Publication Publication Date Title
IL117035A (en) Paroxetine hydrochloride anhydrate substantially free of bound propan-2-ol processes for its preparation and pharmaceutical compositions containing it
ZA968907B (en) Compositions and methods for buccal delivery of pharmaceutical agents
IL116486A0 (en) Novel piperidine derivatives processes for their preparation and pharmaceutical compositions containing them
HUP9701281A2 (en) Piperidine derivatives as neurokinin antagonists and pharmaceutical compositions containing them
PL351492A1 (en) Novel polymorphic forms of an antidiabetic agent: process for their preparation and pharmaceutical compositions containing them
HUP0002183A3 (en) Pharmaceutical composition for combination of piperidinoalkanol-decongestant
HUP9900467A3 (en) Novel acid-labile pharmaceutical composition containing omeprazole and process for its preparation
HUP0100731A3 (en) New oxazolidine-, thiazolidine-, pyrrolidine-and piperidin derivatives process for their preparation and pharmaceutical compositions containing them
AP2001002270A0 (en) Metalloproteinaise inhibitors pharmaceutical compositions containing them and their pharmaceeutical uses and methods and intermediates useful for their preparation
ZA969001B (en) Method compositions and kits for increasing the oral bioavailability of pharmaceutical agents
SI0807111T1 (en) Substituted heterocyclic compounds, preparation method therefor and pharmaceutical compositions containing same
HUP9601285A3 (en) Substituted n-(indole-2-carbonyl)-beta-alaninamides and derivatives and pharmaceutical compositions containing them
IL119647A0 (en) Crystalline hydrochloride of (R)-(-)-2-[N-[4-(1,I-dioxido- 3-oxo-2,3-dihydro-benzisothiazol-2-yl)-butyl]-aminomethyl]-chroman its preparation and a pharmaceutical composition containing it
HUP0000088A3 (en) N-substituted azaheterocyclic compounds, process for producing them and pharmaceutical compositions containing them
HUP0004008A3 (en) Polymorphic form of a morpholine derivative having tachykinin receptor antagonist activity and pharmaceutical compositions containing the same
IL115771A (en) Apolipoprotein-B synthesis inhibitors their preparation and pharmaceutical compositions containing them
HUP0003198A2 (en) Thermodynamically stable modification of 1-(4-carbazoly-loxy)-3-[2-(2-(methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it
IL115324A0 (en) Neurokinin antagonist compounds their preparation and pharmaceutical compositions containing them
GB9710800D0 (en) Pharmaceutical composition and method of preparing it
HUP0000960A3 (en) Spray-dried paroxetine hydrochloride, process for it's preparation,use of the compound and pharmaceutical compositions containing the same
IL116539A0 (en) Compositions for transdermal delivery of acid-labile drugs
EG23781A (en) Pharmaceutical composition containing tiagabine hydrochloride and the process for its preparation
HUP9800970A3 (en) Process for producing pharmaceutical compositions containing heptapeptide somatostatin derivatives of neurogene- and non-neurogene-antiflogistic and analgesic activity and peptidomimetica
HUP0103134A2 (en) Process for preparation crystalline forms of osanetant and pharmaceutical compositions containing them
HUP0100019A3 (en) Novel polymorphic forms of cipamfylline, process for their preparation and pharmaceutical compositions thereof