IE811951L - Oxazaphosphorins - Google Patents
OxazaphosphorinsInfo
- Publication number
- IE811951L IE811951L IE811951A IE195181A IE811951L IE 811951 L IE811951 L IE 811951L IE 811951 A IE811951 A IE 811951A IE 195181 A IE195181 A IE 195181A IE 811951 L IE811951 L IE 811951L
- Authority
- IE
- Ireland
- Prior art keywords
- oxazaphosphorins
- carbamoyloxyoxazaphosphorines
- novel
- processes
- preparation
- Prior art date
Links
- ZZVDXRCAGGQFAK-UHFFFAOYSA-N 2h-oxazaphosphinine Chemical class N1OC=CC=P1 ZZVDXRCAGGQFAK-UHFFFAOYSA-N 0.000 title 1
- VZZWPFPWQGVAHK-UHFFFAOYSA-N 2h-oxazaphosphinin-4-yl carbamate Chemical class NC(=O)OC1=PNOC=C1 VZZWPFPWQGVAHK-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
The present invention relates to novel 4-carbamoyloxyoxazaphosphorines of the general formula I <IMAGE> to processes for their preparation, and to pharmaceutical preparations containing these active compounds.
[FR2489825A1]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8029222 | 1980-09-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE811951L true IE811951L (en) | 1982-03-10 |
IE51784B1 IE51784B1 (en) | 1987-04-01 |
Family
ID=10515985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1951/81A IE51784B1 (en) | 1980-09-10 | 1981-08-25 | 4-carbamoyloxy-oxazaphosphorins,method of producing them and pharmaceutical preparations containing them |
Country Status (29)
Country | Link |
---|---|
JP (1) | JPS5785396A (en) |
AR (1) | AR231989A1 (en) |
AT (1) | AT386210B (en) |
AU (1) | AU538275B2 (en) |
BE (1) | BE890276A (en) |
CA (2) | CA1161453A (en) |
CH (1) | CH650787A5 (en) |
CS (1) | CS227680B2 (en) |
DD (1) | DD202166A5 (en) |
DE (1) | DE3133309A1 (en) |
DK (1) | DK400481A (en) |
EG (1) | EG15392A (en) |
ES (1) | ES505324A0 (en) |
FI (1) | FI70026C (en) |
FR (1) | FR2489825A1 (en) |
GR (1) | GR75300B (en) |
HU (1) | HU185953B (en) |
IE (1) | IE51784B1 (en) |
IL (1) | IL63661A (en) |
IT (2) | IT1198350B (en) |
LU (1) | LU83613A1 (en) |
NL (1) | NL8104093A (en) |
NO (1) | NO161261C (en) |
PL (1) | PL128627B1 (en) |
PT (1) | PT73645B (en) |
RO (1) | RO83972B (en) |
SE (1) | SE458203B (en) |
YU (1) | YU42584B (en) |
ZA (1) | ZA815922B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA851062B (en) * | 1984-03-01 | 1985-11-27 | Asta Werke Ag Chem Fab | Salts of oxazaphosphorine derivatives and process for their production |
DE3569737D1 (en) * | 1984-03-01 | 1989-06-01 | Asta Pharma Ag | Salts of oxazaphosphorine derivatives |
WO2016089208A2 (en) | 2014-12-04 | 2016-06-09 | Stichting Maastricht Radiation Oncology "Maastro-Clinic" | Sulfonamide, sulfamate and sulfamide derivatives of anti-cancer agents |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA955937A (en) * | 1971-06-28 | 1974-10-08 | Shionogi And Co. Ltd. | Cyclic phosphamide derivatives |
US3911005A (en) * | 1974-09-12 | 1975-10-07 | Monsanto Co | 1,3,2-Diazaphospholidine compounds |
JPS5159886A (en) * | 1974-11-20 | 1976-05-25 | Shionogi Seiyaku Kk |
-
1981
- 1981-08-22 DE DE19813133309 patent/DE3133309A1/en active Granted
- 1981-08-25 IE IE1951/81A patent/IE51784B1/en unknown
- 1981-08-26 AU AU74657/81A patent/AU538275B2/en not_active Ceased
- 1981-08-26 IL IL63661A patent/IL63661A/en not_active IP Right Cessation
- 1981-08-26 ZA ZA815922A patent/ZA815922B/en unknown
- 1981-08-31 CH CH5584/81A patent/CH650787A5/en not_active IP Right Cessation
- 1981-08-31 GR GR65896A patent/GR75300B/el unknown
- 1981-09-03 NL NL8104093A patent/NL8104093A/en not_active Application Discontinuation
- 1981-09-04 CS CS816537A patent/CS227680B2/en unknown
- 1981-09-07 AT AT0386481A patent/AT386210B/en not_active IP Right Cessation
- 1981-09-07 LU LU83613A patent/LU83613A1/en unknown
- 1981-09-08 DD DD81233132A patent/DD202166A5/en unknown
- 1981-09-08 EG EG508/81A patent/EG15392A/en active
- 1981-09-08 FR FR8116999A patent/FR2489825A1/en active Granted
- 1981-09-08 RO RO105257A patent/RO83972B/en unknown
- 1981-09-08 HU HU812580A patent/HU185953B/en unknown
- 1981-09-08 SE SE8105340A patent/SE458203B/en not_active IP Right Cessation
- 1981-09-09 PL PL1981232960A patent/PL128627B1/en unknown
- 1981-09-09 DK DK400481A patent/DK400481A/en not_active Application Discontinuation
- 1981-09-09 NO NO813063A patent/NO161261C/en unknown
- 1981-09-09 BE BE2/59345A patent/BE890276A/en not_active IP Right Cessation
- 1981-09-09 JP JP56141108A patent/JPS5785396A/en active Granted
- 1981-09-09 ES ES505324A patent/ES505324A0/en active Granted
- 1981-09-09 FI FI812798A patent/FI70026C/en not_active IP Right Cessation
- 1981-09-09 IT IT23860/81A patent/IT1198350B/en active
- 1981-09-09 CA CA000385516A patent/CA1161453A/en not_active Expired
- 1981-09-09 PT PT73645A patent/PT73645B/en unknown
- 1981-09-10 AR AR286736A patent/AR231989A1/en active
- 1981-09-10 YU YU2179/81A patent/YU42584B/en unknown
-
1984
- 1984-05-30 CA CA000455507A patent/CA1184563B/en not_active Expired
- 1984-06-12 IT IT21372/84A patent/IT1220985B/en active
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