HUT49317A - Process for producing 16-dehydro-d3-vitamine derivatives and pharmaceutical compositions containing them - Google Patents

Process for producing 16-dehydro-d3-vitamine derivatives and pharmaceutical compositions containing them

Info

Publication number
HUT49317A
HUT49317A HU89175A HU17589A HUT49317A HU T49317 A HUT49317 A HU T49317A HU 89175 A HU89175 A HU 89175A HU 17589 A HU17589 A HU 17589A HU T49317 A HUT49317 A HU T49317A
Authority
HU
Hungary
Prior art keywords
dehydro
producing
pharmaceutical compositions
compositions containing
vitamine
Prior art date
Application number
HU89175A
Other languages
English (en)
Other versions
HU201007B (en
Inventor
Enrico G Baggiolini
Bernard M Hennessy
Shian J Shiuey
Gary A Truitt
Milan R Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HUT49317A publication Critical patent/HUT49317A/hu
Publication of HU201007B publication Critical patent/HU201007B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU89175A 1988-01-20 1989-01-18 Process for producing 16-dehydro-d under 3-vitamin derivatives and pharmaceutical compositions comprising same HU201007B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14593288A 1988-01-20 1988-01-20

Publications (2)

Publication Number Publication Date
HUT49317A true HUT49317A (en) 1989-09-28
HU201007B HU201007B (en) 1990-09-28

Family

ID=22515181

Family Applications (1)

Application Number Title Priority Date Filing Date
HU89175A HU201007B (en) 1988-01-20 1989-01-18 Process for producing 16-dehydro-d under 3-vitamin derivatives and pharmaceutical compositions comprising same

Country Status (23)

Country Link
EP (1) EP0325279B1 (hu)
JP (1) JPH0764806B2 (hu)
KR (1) KR960009119B1 (hu)
AR (1) AR247551A1 (hu)
AT (1) ATE74350T1 (hu)
AU (1) AU622139B2 (hu)
BG (1) BG60530B2 (hu)
CA (1) CA1337529C (hu)
DE (1) DE58901056D1 (hu)
DK (1) DK169945B1 (hu)
ES (1) ES2033467T3 (hu)
FI (1) FI90764C (hu)
GR (1) GR3004786T3 (hu)
HU (1) HU201007B (hu)
IE (1) IE60921B1 (hu)
IL (1) IL88989A (hu)
MC (1) MC1998A1 (hu)
NO (1) NO175429C (hu)
NZ (1) NZ227641A (hu)
PH (1) PH25605A (hu)
PT (1) PT89486B (hu)
YU (1) YU47298B (hu)
ZA (1) ZA8923B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
EP0398217B1 (de) * 1989-05-18 1994-01-12 F. Hoffmann-La Roche Ag Dehydrocholecalciferolderivate
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
ES2091515T3 (es) * 1992-05-20 1996-11-01 Hoffmann La Roche Analogos fluorados de la vitamina d3.
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
TW267161B (hu) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
AU708679B2 (en) * 1996-03-21 1999-08-12 F. Hoffmann-La Roche Ag 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
ATE237586T1 (de) * 1997-05-02 2003-05-15 Duphar Int Res Verfahren zur herstellung von 16-dehydro vitamin d verbindungen
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs
US9221753B2 (en) * 2004-02-03 2015-12-29 Chugai Seiyaku Kabushiki Kaisha Process for the synthesis of vitamin D compounds and intermediates for the synthesis of the compounds
CA2605815A1 (en) * 2005-04-25 2006-11-02 Cytochroma Inc. Low-calcemic 16,23-diene 25-oxime analogs of 1alpha,25-dihydroxy vitamin d3
WO2007022433A2 (en) * 2005-08-18 2007-02-22 Bioxell S.P.A. SYNTHESIS OF 1α-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7803154A (nl) * 1977-03-24 1978-09-26 Wisconsin Alumni Res Found Vitamine d-antagonisten, werkwijze voor de be- reiding daarvan, en preparaten die ze bevatten.
DE2920092A1 (de) * 1978-05-19 1979-11-29 Wisconsin Alumni Res Found Antivitamin d-verbindungen und diese enthaltende pharmazeutische zusammensetzungen
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4898855A (en) * 1987-09-14 1990-02-06 Hoffman-La Roche Inc. Deuterated analogs of 1,25-dihydroxycholecalciferol
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
EP0398217B1 (de) * 1989-05-18 1994-01-12 F. Hoffmann-La Roche Ag Dehydrocholecalciferolderivate

Also Published As

Publication number Publication date
KR890011838A (ko) 1989-08-22
IL88989A0 (en) 1989-08-15
YU47298B (sh) 1995-01-31
DK19789D0 (da) 1989-01-17
NO890239L (no) 1989-07-21
AU622139B2 (en) 1992-04-02
EP0325279B1 (de) 1992-04-01
FI90764B (fi) 1993-12-15
IE890157L (en) 1989-07-20
JPH0764806B2 (ja) 1995-07-12
ES2033467T3 (es) 1993-03-16
IE60921B1 (en) 1994-09-07
FI890283A0 (fi) 1989-01-19
PT89486B (pt) 1993-12-31
NO175429B (no) 1994-07-04
FI890283A (fi) 1989-07-21
AR247551A1 (es) 1995-01-31
NO890239D0 (no) 1989-01-19
IL88989A (en) 1993-08-18
MC1998A1 (fr) 1990-01-26
HU201007B (en) 1990-09-28
DE58901056D1 (de) 1992-05-07
BG60530B2 (bg) 1995-07-28
FI90764C (fi) 1994-03-25
PT89486A (pt) 1989-10-04
DK169945B1 (da) 1995-04-10
YU11789A (en) 1991-04-30
ATE74350T1 (de) 1992-04-15
NO175429C (no) 1994-10-12
NZ227641A (en) 1991-06-25
GR3004786T3 (hu) 1993-04-28
EP0325279A1 (de) 1989-07-26
KR960009119B1 (en) 1996-07-13
CA1337529C (en) 1995-11-07
DK19789A (da) 1989-07-21
ZA8923B (en) 1989-09-27
AU2864489A (en) 1989-07-20
JPH029861A (ja) 1990-01-12
PH25605A (en) 1991-08-08

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Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees