HUP0103781A2 - Megismerési képesség javítására szolgáló gyógyszerkészítmények, melyek atipikus antipszihotikus szer és acetilkolinészteráz inhibitor kombinációját tartalmazzák - Google Patents
Megismerési képesség javítására szolgáló gyógyszerkészítmények, melyek atipikus antipszihotikus szer és acetilkolinészteráz inhibitor kombinációját tartalmazzákInfo
- Publication number
- HUP0103781A2 HUP0103781A2 HU0103781A HUP0103781A HUP0103781A2 HU P0103781 A2 HUP0103781 A2 HU P0103781A2 HU 0103781 A HU0103781 A HU 0103781A HU P0103781 A HUP0103781 A HU P0103781A HU P0103781 A2 HUP0103781 A2 HU P0103781A2
- Authority
- HU
- Hungary
- Prior art keywords
- active ingredient
- pharmaceutical compositions
- acetylcholinesterase inhibitor
- atypical
- disease
- Prior art date
Links
- 229940100578 Acetylcholinesterase inhibitor Drugs 0.000 title abstract 2
- 239000000544 cholinesterase inhibitor Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title 1
- 230000019771 cognition Effects 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 4
- 208000024827 Alzheimer disease Diseases 0.000 abstract 2
- 230000009286 beneficial effect Effects 0.000 abstract 2
- 230000003930 cognitive ability Effects 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 239000003693 atypical antipsychotic agent Substances 0.000 abstract 1
- 230000006866 deterioration Effects 0.000 abstract 1
- 230000009931 harmful effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 230000001960 triggered effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A találmány gyógyszerészeti készítményekre vonatkozik, amelyekvivőanyagot és első hatóanyagként valamely (I) atipikusantipszichotikus szert és második hatóanyagként valamely (II) acetil-kolinészteráz-inhibitort tartalmaznak, ahol az egyes komponensek olyanmennyiségben szerepelnek, amely pszichózisban vagy Alzheimer-kórbanvagy hasonló elbutulásos betegségben szenvedő betegeknélgyógyászatilag előnyös hatást vált ki. Ez a gyógyászatilag előnyöshatás, szinergetikus hatás az Alzheimer-kórban vagy hasonlóelbutulásos betegségben szenvedő betegek megismerési képességére vagyaz ezen betegekben a kognitív képesség további romlásánakmegelőzésére, vagy az egyik hatóanyagnak a másik hatóanyag általokozott káros hatásai csökkentésére. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98203454 | 1998-10-16 | ||
| PCT/EP1999/007804 WO2000023057A2 (en) | 1998-10-16 | 1999-10-12 | Atypical antiphsychotic in combination with acetylcholinesterase inhibitor for improving cognition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0103781A2 true HUP0103781A2 (hu) | 2002-03-28 |
| HUP0103781A3 HUP0103781A3 (en) | 2003-09-29 |
Family
ID=8234219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0103781A HUP0103781A3 (en) | 1998-10-16 | 1999-10-12 | Pharmaceutical compositions comprising atypical antiphsychotic agent in combination with acetylcholinesterase inhibitor for improving cognition |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1121131A2 (hu) |
| JP (1) | JP2002527469A (hu) |
| KR (1) | KR20010072878A (hu) |
| CN (1) | CN1367697A (hu) |
| AU (1) | AU6472799A (hu) |
| BG (1) | BG105302A (hu) |
| BR (1) | BR9914419A (hu) |
| CA (1) | CA2345767A1 (hu) |
| EE (1) | EE200100136A (hu) |
| HK (1) | HK1039745A1 (hu) |
| HR (1) | HRP20010262A2 (hu) |
| HU (1) | HUP0103781A3 (hu) |
| ID (1) | ID28441A (hu) |
| IL (1) | IL142588A0 (hu) |
| NO (1) | NO20011403D0 (hu) |
| PL (1) | PL348107A1 (hu) |
| SK (1) | SK4592001A3 (hu) |
| TR (1) | TR200101082T2 (hu) |
| WO (1) | WO2000023057A2 (hu) |
| ZA (1) | ZA200103081B (hu) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006201188B2 (en) * | 2001-02-05 | 2007-11-15 | Novartis Ag | New use of iloperidone |
| GB0102841D0 (en) * | 2001-02-05 | 2001-03-21 | Novartis Ag | Organic compounds |
| ES2358416T3 (es) | 2001-10-30 | 2011-05-10 | Novartis Ag | Formulaciones de liberación prolongada de iloperidona y polímero en forma de estrella. |
| GB0216416D0 (en) | 2002-07-15 | 2002-08-21 | Novartis Ag | Organic compounds |
| US20040192754A1 (en) * | 2003-03-24 | 2004-09-30 | Shapira Nathan Andrew | Methods for treating idiopathic hyperhidrosis and associated conditions |
| TW200501962A (en) * | 2003-04-01 | 2005-01-16 | Novartis Ag | Use of carbamazepine derivatives for the treatment of agitation in dementia patients |
| EP1824848A1 (en) * | 2004-12-10 | 2007-08-29 | Abbott Laboratories | Fused bicycloheterocycle substituted quinuclidine derivatives |
| CA2552221A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Donepezil formulations |
| US8278345B2 (en) | 2006-11-09 | 2012-10-02 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| DK2091948T3 (da) | 2006-11-30 | 2012-07-23 | Probiodrug Ag | Nye inhibitorer af glutaminylcyclase |
| ZA200905537B (en) | 2007-03-01 | 2010-10-27 | Probiodrug Ag | New use of glutaminyl cyclase inhibitors |
| US9656991B2 (en) | 2007-04-18 | 2017-05-23 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| MX2007008642A (es) * | 2007-07-16 | 2009-02-25 | World Trade Imp Export Wtie Ag | Composicion farmaceutica que comprende la combinacion de un agente derivado benzisoxazolico y un agente inhibidor reversible de la enzima colinesterasa, indicada para el control y tratamiento de trastornos psicoticos y demencias. |
| CN102905532A (zh) | 2010-02-09 | 2013-01-30 | 约翰斯.霍普金斯大学 | 用于改善认知功能的方法和组合物 |
| WO2011107530A2 (en) | 2010-03-03 | 2011-09-09 | Probiodrug Ag | Novel inhibitors |
| MX2012010470A (es) | 2010-03-10 | 2012-10-09 | Probiodrug Ag | Inhibidores heterociclicos d ciclasa de glutaminilo (qc, ec .3 2. 5). |
| WO2011131748A2 (en) | 2010-04-21 | 2011-10-27 | Probiodrug Ag | Novel inhibitors |
| WO2012123563A1 (en) | 2011-03-16 | 2012-09-20 | Probiodrug Ag | Benz imidazole derivatives as inhibitors of glutaminyl cyclase |
| EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| AU2014228512A1 (en) | 2013-03-15 | 2015-10-01 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
| CN112843005B (zh) | 2015-05-22 | 2023-02-21 | 艾吉因生物股份有限公司 | 左乙拉西坦的延时释放药物组合物 |
| ES2812698T3 (es) | 2017-09-29 | 2021-03-18 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69229781T2 (de) * | 1991-05-14 | 2000-01-05 | Ernir Snorrason | Behandlung des ermüdungssyndroms mit cholinesteraseinhibitoren |
| US5336675A (en) * | 1991-05-14 | 1994-08-09 | Ernir Snorrason | Method of treating mania in humans |
| WO1999007378A1 (en) * | 1997-08-11 | 1999-02-18 | THE UNIVERSITY OF SOUTH FLORIDA A Corporation of the State of Florida | Nicotine antagonists for nicotine-responsive neuropsychiatric disorders |
| IL139008A0 (en) * | 1998-04-14 | 2001-11-25 | Gen Hospital Corp | Methods for treating neuropsychiatric disorders |
-
1999
- 1999-10-12 HU HU0103781A patent/HUP0103781A3/hu unknown
- 1999-10-12 WO PCT/EP1999/007804 patent/WO2000023057A2/en not_active Application Discontinuation
- 1999-10-12 ID IDW20010828A patent/ID28441A/id unknown
- 1999-10-12 EE EEP200100136A patent/EE200100136A/xx unknown
- 1999-10-12 TR TR2001/01082T patent/TR200101082T2/xx unknown
- 1999-10-12 AU AU64727/99A patent/AU6472799A/en not_active Abandoned
- 1999-10-12 KR KR1020017002286A patent/KR20010072878A/ko not_active Application Discontinuation
- 1999-10-12 PL PL99348107A patent/PL348107A1/xx unknown
- 1999-10-12 SK SK459-2001A patent/SK4592001A3/sk unknown
- 1999-10-12 BR BR9914419-0A patent/BR9914419A/pt not_active IP Right Cessation
- 1999-10-12 CA CA002345767A patent/CA2345767A1/en not_active Abandoned
- 1999-10-12 IL IL14258899A patent/IL142588A0/xx unknown
- 1999-10-12 JP JP2000576832A patent/JP2002527469A/ja not_active Withdrawn
- 1999-10-12 CN CN99812184A patent/CN1367697A/zh active Pending
- 1999-10-12 EP EP99952580A patent/EP1121131A2/en not_active Withdrawn
-
2001
- 2001-03-01 BG BG105302A patent/BG105302A/xx unknown
- 2001-03-20 NO NO20011403A patent/NO20011403D0/no not_active Application Discontinuation
- 2001-04-10 HR HR20010262A patent/HRP20010262A2/hr not_active Application Discontinuation
- 2001-04-12 ZA ZA200103081A patent/ZA200103081B/en unknown
-
2002
- 2002-01-10 HK HK02100158.6A patent/HK1039745A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6472799A (en) | 2000-05-08 |
| EE200100136A (et) | 2002-06-17 |
| WO2000023057A2 (en) | 2000-04-27 |
| HK1039745A1 (zh) | 2002-05-10 |
| NO20011403L (no) | 2001-03-20 |
| NO20011403D0 (no) | 2001-03-20 |
| CA2345767A1 (en) | 2000-04-27 |
| HUP0103781A3 (en) | 2003-09-29 |
| BG105302A (en) | 2001-11-30 |
| IL142588A0 (en) | 2002-03-10 |
| EP1121131A2 (en) | 2001-08-08 |
| WO2000023057A3 (en) | 2000-07-27 |
| ZA200103081B (en) | 2002-07-12 |
| BR9914419A (pt) | 2001-06-26 |
| CN1367697A (zh) | 2002-09-04 |
| TR200101082T2 (tr) | 2001-09-21 |
| JP2002527469A (ja) | 2002-08-27 |
| SK4592001A3 (en) | 2001-12-03 |
| KR20010072878A (ko) | 2001-07-31 |
| PL348107A1 (en) | 2002-05-06 |
| HRP20010262A2 (en) | 2002-06-30 |
| ID28441A (id) | 2001-05-24 |
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