HUP0001873A3 - Amidino-1,4-benzoxazepine derivatives, process for their preparation, their use and pharmaceutical compositions containing them - Google Patents

Amidino-1,4-benzoxazepine derivatives, process for their preparation, their use and pharmaceutical compositions containing them

Info

Publication number
HUP0001873A3
HUP0001873A3 HU0001873A HUP0001873A HUP0001873A3 HU P0001873 A3 HUP0001873 A3 HU P0001873A3 HU 0001873 A HU0001873 A HU 0001873A HU P0001873 A HUP0001873 A HU P0001873A HU P0001873 A3 HUP0001873 A3 HU P0001873A3
Authority
HU
Hungary
Prior art keywords
amidino
preparation
pharmaceutical compositions
compositions containing
benzoxazepine derivatives
Prior art date
Application number
HU0001873A
Other languages
English (en)
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of HUP0001873A2 publication Critical patent/HUP0001873A2/hu
Publication of HUP0001873A3 publication Critical patent/HUP0001873A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU0001873A 1997-05-05 1998-04-28 Amidino-1,4-benzoxazepine derivatives, process for their preparation, their use and pharmaceutical compositions containing them HUP0001873A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9701681A SE9701681D0 (sv) 1997-05-05 1997-05-05 New compounds

Publications (2)

Publication Number Publication Date
HUP0001873A2 HUP0001873A2 (hu) 2001-01-29
HUP0001873A3 true HUP0001873A3 (en) 2001-12-28

Family

ID=20406835

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001873A HUP0001873A3 (en) 1997-05-05 1998-04-28 Amidino-1,4-benzoxazepine derivatives, process for their preparation, their use and pharmaceutical compositions containing them

Country Status (25)

Country Link
US (1) US6489322B1 (hu)
EP (1) EP0983268B1 (hu)
JP (1) JP2001523262A (hu)
KR (1) KR20010012228A (hu)
CN (1) CN1255131A (hu)
AR (1) AR012601A1 (hu)
AT (1) ATE221065T1 (hu)
AU (1) AU734391B2 (hu)
BR (1) BR9809218A (hu)
CA (1) CA2288333A1 (hu)
DE (1) DE69806750T2 (hu)
EE (1) EE9900474A (hu)
HU (1) HUP0001873A3 (hu)
ID (1) ID22885A (hu)
IL (1) IL132678A0 (hu)
IS (1) IS5236A (hu)
MX (1) MXPA99009882A (hu)
NO (1) NO995403L (hu)
NZ (1) NZ500675A (hu)
PL (1) PL336853A1 (hu)
SE (1) SE9701681D0 (hu)
SK (1) SK140599A3 (hu)
TR (1) TR199902720T2 (hu)
WO (1) WO1998050382A1 (hu)
ZA (1) ZA983736B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI243164B (en) * 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US8896004B2 (en) * 2005-04-26 2014-11-25 Kabushiki Kaisha Toshiba White LED, backlight using the same, and liquid crystal display device
US20100105657A1 (en) * 2005-07-05 2010-04-29 Astrazeneca Ab Compounds, Process for their Preparation, Intermediates, Pharmaceutical Compositions and their use in the Treatment of 5-HT6 Mediated Disorders such as Alzheimer's Disease, Cognitive Disorders, Cognitive Impairment Associated with Schizophrenia, Obesity and Parkinson's Disease
MY148644A (en) 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
WO2008053446A2 (en) * 2006-11-02 2008-05-08 Piramal Life Sciences Limited Benzoxazepine compounds, their preparation and use
WO2008108445A1 (ja) 2007-03-07 2008-09-12 Takeda Pharmaceutical Company Limited ベンゾオキサゼピン誘導体およびその用途
WO2008144483A2 (en) * 2007-05-18 2008-11-27 Armgo Pharma, Inc. Agents for treating disorders involving modulation of ryanodine receptors
CA2763099A1 (en) * 2009-05-22 2010-11-25 Exelixis, Inc. Benzoxazepines based p13k/mt0r inhibitors against proliferative diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09504278A (ja) 1944-06-01 1997-04-28 ザ、ウェルカム、ファンデーション、リミテッド Noシンターゼインヒビターとしての置換尿素およびイソチオ尿素誘導体
RU2130017C1 (ru) 1993-08-12 1999-05-10 Астра Актиенболаг Производные амидина, способ их получения и лекарственное средство на их основе, обладающее свойством ингибировать активность синтетазы оксида азота (у)
JPH09504028A (ja) 1993-10-21 1997-04-22 ジー.ディー.サール アンド カンパニー 酸化窒素シンターゼ抑制剤として有用なアミジノ誘導体
WO1996001817A1 (en) * 1994-05-07 1996-01-25 Astra Aktiebolag Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase
TW397812B (en) * 1995-02-11 2000-07-11 Astra Ab Bicyclic isothiourea derivatives useful in therapy
BR9509297A (pt) * 1995-08-10 1998-07-07 Astra Ab Composto composição farmacêutica utilização de um composto e processos de tratamento ou prolifaxia de uma doença ou condição na qual a síntese ou suprasintese da sintetase de óxido nitrico forma uma parte contribuinte e desordens neurodegenerativas ou de enxaqueca ou de prevenção e reversão da tolerância a opiatos e diazepinas ou de tratamento do vicio em tóxicos e de preparação de um composto
TW458978B (en) * 1995-11-07 2001-10-11 Astra Ab Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase

Also Published As

Publication number Publication date
NO995403L (no) 2000-01-05
IS5236A (is) 1999-11-01
CN1255131A (zh) 2000-05-31
HUP0001873A2 (hu) 2001-01-29
ZA983736B (en) 1998-11-05
DE69806750D1 (de) 2002-08-29
SE9701681D0 (sv) 1997-05-05
JP2001523262A (ja) 2001-11-20
MXPA99009882A (es) 2005-11-22
AU734391B2 (en) 2001-06-14
ATE221065T1 (de) 2002-08-15
US6489322B1 (en) 2002-12-03
DE69806750T2 (de) 2003-03-06
EP0983268B1 (en) 2002-07-24
AU7459898A (en) 1998-11-27
NZ500675A (en) 2001-05-25
WO1998050382A1 (en) 1998-11-12
KR20010012228A (ko) 2001-02-15
EE9900474A (et) 2000-06-15
NO995403D0 (no) 1999-11-04
TR199902720T2 (xx) 2000-02-21
AR012601A1 (es) 2000-11-08
PL336853A1 (en) 2000-07-17
EP0983268A1 (en) 2000-03-08
BR9809218A (pt) 2000-06-27
ID22885A (id) 1999-12-16
CA2288333A1 (en) 1998-11-12
SK140599A3 (en) 2000-06-12
IL132678A0 (en) 2001-03-19

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