HUE036982T2 - GPCR:G-fehérje komplexek ellen irányuló kötõdomének és alkalmazások - Google Patents

GPCR:G-fehérje komplexek ellen irányuló kötõdomének és alkalmazások

Info

Publication number
HUE036982T2
HUE036982T2 HUE12730478A HUE12730478A HUE036982T2 HU E036982 T2 HUE036982 T2 HU E036982T2 HU E12730478 A HUE12730478 A HU E12730478A HU E12730478 A HUE12730478 A HU E12730478A HU E036982 T2 HUE036982 T2 HU E036982T2
Authority
HU
Hungary
Prior art keywords
directed against
binding domains
protein complexes
domains directed
uses derived
Prior art date
Application number
HUE12730478A
Other languages
English (en)
Inventor
Jan Steyaert
Els Pardon
Toon Laeremans
Brian Kobilka
Soeren Rasmussen
Sebastien Granier
Roger Sunahara
Original Assignee
Vib Vzw
Univ Brussel Vrije
Univ Leland Stanford Junior
Univ Michigan Regents
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vib Vzw, Univ Brussel Vrije, Univ Leland Stanford Junior, Univ Michigan Regents filed Critical Vib Vzw
Publication of HUE036982T2 publication Critical patent/HUE036982T2/hu

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4722G-proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HUE12730478A 2011-06-21 2012-06-21 GPCR:G-fehérje komplexek ellen irányuló kötõdomének és alkalmazások HUE036982T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161571159P 2011-06-21 2011-06-21
EP11181357 2011-09-15

Publications (1)

Publication Number Publication Date
HUE036982T2 true HUE036982T2 (hu) 2018-08-28

Family

ID=47423019

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE12730478A HUE036982T2 (hu) 2011-06-21 2012-06-21 GPCR:G-fehérje komplexek ellen irányuló kötõdomének és alkalmazások

Country Status (14)

Country Link
US (3) US9695227B2 (hu)
EP (3) EP4282882A3 (hu)
JP (2) JP6164535B2 (hu)
CN (2) CN104053667B (hu)
AU (1) AU2012273987B2 (hu)
CA (1) CA2839834A1 (hu)
DK (1) DK2723764T3 (hu)
ES (1) ES2662372T3 (hu)
HR (1) HRP20180443T1 (hu)
HU (1) HUE036982T2 (hu)
NO (1) NO2723764T3 (hu)
PL (1) PL2723764T3 (hu)
PT (1) PT2723764T (hu)
WO (1) WO2012175643A2 (hu)

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WO2019155041A1 (en) * 2018-02-12 2019-08-15 Vib Vzw Gβγ COMPLEX ANTIBODIES AND USES THEREOF
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GB2590196A (en) 2018-05-18 2021-06-23 Twist Bioscience Corp Polynucleotides, reagents, and methods for nucleic acid hybridization
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Also Published As

Publication number Publication date
US20170253644A1 (en) 2017-09-07
WO2012175643A2 (en) 2012-12-27
EP4282882A3 (en) 2024-03-06
HRP20180443T1 (hr) 2018-04-20
EP2723764B1 (en) 2017-12-27
EP4282882A2 (en) 2023-11-29
JP2017127306A (ja) 2017-07-27
EP2723764A2 (en) 2014-04-30
JP2014525735A (ja) 2014-10-02
AU2012273987B2 (en) 2017-01-05
BR112013032451A2 (pt) 2016-11-22
AU2012273987A1 (en) 2014-01-30
ES2662372T3 (es) 2018-04-06
CN104053667B (zh) 2017-09-15
NO2723764T3 (hu) 2018-05-26
DK2723764T3 (en) 2018-03-12
JP6164535B2 (ja) 2017-07-19
WO2012175643A3 (en) 2013-06-13
US20140275487A1 (en) 2014-09-18
EP3345919A1 (en) 2018-07-11
PL2723764T3 (pl) 2018-05-30
PT2723764T (pt) 2018-03-09
US9695227B2 (en) 2017-07-04
US20200239534A1 (en) 2020-07-30
US10626154B2 (en) 2020-04-21
CA2839834A1 (en) 2012-12-27
CN104053667A (zh) 2014-09-17
CN107857810A (zh) 2018-03-30

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