GB950509A - Improvements in or relating to piperazides - Google Patents

Improvements in or relating to piperazides

Info

Publication number
GB950509A
GB950509A GB1137961A GB1137961A GB950509A GB 950509 A GB950509 A GB 950509A GB 1137961 A GB1137961 A GB 1137961A GB 1137961 A GB1137961 A GB 1137961A GB 950509 A GB950509 A GB 950509A
Authority
GB
United Kingdom
Prior art keywords
hydroxyalkyl
alkanoyloxyalkyl
alkyl
piperazides
pyrid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1137961A
Inventor
Richard A Robinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Priority to GB1137961A priority Critical patent/GB950509A/en
Publication of GB950509A publication Critical patent/GB950509A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises piperazides (anti-inflammatory agents and pepsin inhibitors) of the general formula I, <FORM:0950509/C2/1> (wherein Alk is an alkylene radical, and R is a hydrogen atom or an alkyl, hydroxyalkyl or alkanoyloxyalkyl radical), and a process for their preparation by condensing a 9-carboxyalkyl -9-pyrid [3, 4-b]indole halide, azide or alkyl ester with piperazine or an N-alkyl-, hydroxyalkyl- or alkanoyloxyalkyl-piperazine; I (R=alkanoyloxyalkyl) may alternatively be prepared by esterification of I (R=hydroxyalkyl). The halide, azide and alkyl ester starting materials are prepared from 9-pyrid [3,4-b]indole by standard methods.
GB1137961A 1961-03-28 1961-03-28 Improvements in or relating to piperazides Expired GB950509A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1137961A GB950509A (en) 1961-03-28 1961-03-28 Improvements in or relating to piperazides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1137961A GB950509A (en) 1961-03-28 1961-03-28 Improvements in or relating to piperazides

Publications (1)

Publication Number Publication Date
GB950509A true GB950509A (en) 1964-02-26

Family

ID=9985158

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1137961A Expired GB950509A (en) 1961-03-28 1961-03-28 Improvements in or relating to piperazides

Country Status (1)

Country Link
GB (1) GB950509A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022989A1 (en) * 1995-01-23 1996-08-01 Schering Aktiengesellschaft Novel 9h-pyrido[3,4-b]indol derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022989A1 (en) * 1995-01-23 1996-08-01 Schering Aktiengesellschaft Novel 9h-pyrido[3,4-b]indol derivatives
US5880126A (en) * 1995-01-23 1999-03-09 Schering Aktiengesellschaft 9H-Pyridu ((3,4-b) indole derivatives

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