GB201608227D0 - Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer - Google Patents

Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer

Info

Publication number
GB201608227D0
GB201608227D0 GBGB1608227.3A GB201608227A GB201608227D0 GB 201608227 D0 GB201608227 D0 GB 201608227D0 GB 201608227 A GB201608227 A GB 201608227A GB 201608227 D0 GB201608227 D0 GB 201608227D0
Authority
GB
United Kingdom
Prior art keywords
quinolin
imidazo
compounds
treating cancer
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1608227.3A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Priority to GBGB1608227.3A priority Critical patent/GB201608227D0/en
Publication of GB201608227D0 publication Critical patent/GB201608227D0/en
Priority to PCT/EP2017/061229 priority patent/WO2017194632A1/en
Priority to TW106115396A priority patent/TW201805284A/en
Priority to ARP170101261A priority patent/AR108461A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB1608227.3A 2016-05-11 2016-05-11 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer Ceased GB201608227D0 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GBGB1608227.3A GB201608227D0 (en) 2016-05-11 2016-05-11 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
PCT/EP2017/061229 WO2017194632A1 (en) 2016-05-11 2017-05-10 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
TW106115396A TW201805284A (en) 2016-05-11 2017-05-10 Imidazo[4,5-C]quinolin-2-one compounds and their use in treating cancer
ARP170101261A AR108461A1 (en) 2016-05-11 2017-05-11 IMIDAZO COMPOUNDS [4,5-C] QUINOLIN-2-ONA AND ITS USE IN CANCER TREATMENT

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1608227.3A GB201608227D0 (en) 2016-05-11 2016-05-11 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer

Publications (1)

Publication Number Publication Date
GB201608227D0 true GB201608227D0 (en) 2016-06-22

Family

ID=56297492

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1608227.3A Ceased GB201608227D0 (en) 2016-05-11 2016-05-11 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer

Country Status (4)

Country Link
AR (1) AR108461A1 (en)
GB (1) GB201608227D0 (en)
TW (1) TW201805284A (en)
WO (1) WO2017194632A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110386932A (en) * 2018-04-20 2019-10-29 艾科思莱德制药公司 For the dual ATM and DNA-PK inhibitor in antitumor therapy
WO2019201283A1 (en) * 2018-04-20 2019-10-24 Xrad Therapeutics, Inc. Dual atm and dna-pk inhibitors for use in anti-tumor therapy
CA3111994A1 (en) * 2018-09-14 2020-03-19 Suzhou Zanrong Pharma Limited 1-isopropyl-3-methyl-8-(pyridin-3-yl)-1,3-dihydro-2h-imidazo[4,5-c]cinnolin-2-one as selective modulators of ataxia telangiectasia mutated (atm) kinase and uses thereof
KR102345208B1 (en) * 2018-09-30 2021-12-30 메드샤인 디스커버리 아이엔씨. Quinolino-pyrrolidin-2-one derivatives and their applications
WO2021098734A1 (en) * 2019-11-19 2021-05-27 南京明德新药研发有限公司 Substituted quinolinopyrrolidone compound as atm inhibitor and application thereof
CN115003672A (en) * 2020-01-09 2022-09-02 南京明德新药研发有限公司 Quinoline imidazole compound and application thereof
WO2021197339A1 (en) * 2020-03-30 2021-10-07 南京明德新药研发有限公司 Crystal form of quinopyrrolidine-2-one compound serving as atm inhibitor and use thereof
JP2023539715A (en) 2020-06-24 2023-09-19 アストラゼネカ ユーケー リミテッド Combination of antibody-drug conjugates and ATM inhibitors
EP3992191A1 (en) 2020-11-03 2022-05-04 Deutsches Krebsforschungszentrum Imidazo[4,5-c]quinoline compounds and their use as atm kinase inhibitors
AU2023212227A1 (en) * 2022-01-26 2024-08-15 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Hydrazino group-containing compound
CN115778962B (en) * 2022-11-28 2024-09-17 中国医学科学院肿瘤医院 Medicine for treating male esophageal cancer patient and related application thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
CA2242425C (en) 1996-02-13 2006-07-18 Zeneca Limited Quinazoline derivatives as vegf inhibitors
CA2244897C (en) 1996-03-05 2006-04-11 Zeneca Limited 4-anilinoquinazoline derivatives
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
CN102372711B (en) 2010-08-18 2014-09-17 山东轩竹医药科技有限公司 Imidazo quinoline PI3K and mTOR (mammalian target of rapamycin) dual inhibitor
CN102399218A (en) 2010-09-16 2012-04-04 和记黄埔医药（上海）有限公司 Triheterocyclic compounds and their use as PI3K inhibitors
NO2714752T3 (en) * 2014-05-08 2018-04-21
GB201516504D0 (en) * 2015-09-17 2015-11-04 Astrazeneca Ab Imadazo(4,5-c)quinolin-2-one Compounds and their use in treating cancer

Also Published As

Publication number Publication date
WO2017194632A1 (en) 2017-11-16
AR108461A1 (en) 2018-08-22
TW201805284A (en) 2018-02-16

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)