FR2771093B1 - Derives d'imidazole, leur preparation et leur application en therapeutique - Google Patents

Derives d'imidazole, leur preparation et leur application en therapeutique

Info

Publication number
FR2771093B1
FR2771093B1 FR9714486A FR9714486A FR2771093B1 FR 2771093 B1 FR2771093 B1 FR 2771093B1 FR 9714486 A FR9714486 A FR 9714486A FR 9714486 A FR9714486 A FR 9714486A FR 2771093 B1 FR2771093 B1 FR 2771093B1
Authority
FR
France
Prior art keywords
preparation
therapeutic application
imidazole derivatives
imidazole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9714486A
Other languages
English (en)
Other versions
FR2771093A1 (fr
Inventor
Gilles Victor Car Courtemanche
Gerard Defosse
Olivier Crespin
Philippe R Bovy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR9714486A priority Critical patent/FR2771093B1/fr
Priority to AU12433/99A priority patent/AU1243399A/en
Priority to US09/554,138 priority patent/US6200991B1/en
Priority to EP98955672A priority patent/EP1032569A1/fr
Priority to JP2000521093A priority patent/JP2001523679A/ja
Priority to PCT/FR1998/002446 priority patent/WO1999025710A1/fr
Priority to ARP980105841A priority patent/AR023292A1/es
Priority to CO98067821A priority patent/CO4990949A1/es
Priority to TW087119098A priority patent/TW448170B/zh
Priority to ZA9810558A priority patent/ZA9810558B/xx
Publication of FR2771093A1 publication Critical patent/FR2771093A1/fr
Application granted granted Critical
Publication of FR2771093B1 publication Critical patent/FR2771093B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR9714486A 1997-11-19 1997-11-19 Derives d'imidazole, leur preparation et leur application en therapeutique Expired - Fee Related FR2771093B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR9714486A FR2771093B1 (fr) 1997-11-19 1997-11-19 Derives d'imidazole, leur preparation et leur application en therapeutique
US09/554,138 US6200991B1 (en) 1997-11-19 1998-11-17 Imidazole derivatives, preparation and therapeutic application thereof
EP98955672A EP1032569A1 (fr) 1997-11-19 1998-11-17 Derives d'imidazole, leur preparation et leur application en therapeutique
JP2000521093A JP2001523679A (ja) 1997-11-19 1998-11-17 イミダゾール誘導体、その製造と治療上の用途
PCT/FR1998/002446 WO1999025710A1 (fr) 1997-11-19 1998-11-17 Derives d'imidazole, leur preparation et leur application en therapeutique
AU12433/99A AU1243399A (en) 1997-11-19 1998-11-17 Imidazole derivatives, preparation and therapeutic application thereof
ARP980105841A AR023292A1 (es) 1997-11-19 1998-11-18 Un compuesto derivado de imidazol, un procedimiento para su preparacion, y un medicamento y una composicion farmaceutica que comprende a dicho compuesto
CO98067821A CO4990949A1 (es) 1997-11-19 1998-11-18 Derivados de imidazol y su preparacion .
TW087119098A TW448170B (en) 1997-11-19 1998-11-18 Imidazole derivatives, their preparation and their therapeutic application
ZA9810558A ZA9810558B (en) 1997-11-19 1998-11-18 Imidazole derivatives their preparation and their therapeutic application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9714486A FR2771093B1 (fr) 1997-11-19 1997-11-19 Derives d'imidazole, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2771093A1 FR2771093A1 (fr) 1999-05-21
FR2771093B1 true FR2771093B1 (fr) 2000-01-21

Family

ID=9513524

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9714486A Expired - Fee Related FR2771093B1 (fr) 1997-11-19 1997-11-19 Derives d'imidazole, leur preparation et leur application en therapeutique

Country Status (10)

Country Link
US (1) US6200991B1 (fr)
EP (1) EP1032569A1 (fr)
JP (1) JP2001523679A (fr)
AR (1) AR023292A1 (fr)
AU (1) AU1243399A (fr)
CO (1) CO4990949A1 (fr)
FR (1) FR2771093B1 (fr)
TW (1) TW448170B (fr)
WO (1) WO1999025710A1 (fr)
ZA (1) ZA9810558B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805816B1 (fr) * 2000-03-01 2002-05-17 Sanofi Synthelabo Derives d'haloimidazole, leur preparation et leur application en therapeutique
FR2805815B1 (fr) * 2000-03-01 2002-05-17 Sanofi Synthelabo Derives de polyfluoroalkylimidazole, leur preparation et leur application en therapeutique
US6730796B2 (en) * 2000-10-16 2004-05-04 Chugai Seiyaku Kabushiki Kaisha Process for preparation of N-substituted 2-sulfanylimidazoles
JP4653935B2 (ja) * 2001-03-29 2011-03-16 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド ヒスタミンｈ３受容体のリガンドとして用いるに有用なイミダゾリル誘導体
JP2006511624A (ja) * 2002-12-20 2006-04-06 ダイノジェン ファーマシューティカルズ， インコーポレイテッド α２δサブユニット・カルシウム・チャンネル調節因子を使用する無痛性膀胱障害を処置するための方法
DK1492519T3 (da) * 2003-03-21 2007-03-05 Dynogen Pharmaceuticals Inc Fremgangsmåder til behandling af lidelser i den nedre urinvej ved anvendelse af alfa-2-delta-underenhedscalciumkanalsmodulatorer med glat muskel-modulatorer
US20090156465A1 (en) * 2005-12-30 2009-06-18 Sattigeri Jitendra A Derivatives of beta-amino acid as dipeptidyl peptidase-iv inhibitors
EA200801591A1 (ru) 2005-12-30 2008-12-30 Рэнбакси Лабораториз Лимитед Антагонисты мускаринового рецептора
US20100144801A1 (en) * 2006-10-03 2010-06-10 Naresh Kumar Muscarinic receptor antagonists
EP2129663A2 (fr) * 2007-02-28 2009-12-09 Ranbaxy Laboratories Limited Antagonistes des récepteurs muscariniques
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ223654A (en) * 1987-03-09 1990-03-27 Janssen Pharmaceutica Nv 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions
US5169855A (en) * 1990-03-28 1992-12-08 Du Pont Merck Pharmaceutical Company Piperidine ether derivatives as psychotropic drugs or plant fungicides
FR2747678B1 (fr) * 1996-04-22 1998-05-22 Synthelabo Composes derives d'imidazobenzoxazine, leurs procedes de preparation et leurs utilisations en therapeutique
FR2751647B1 (fr) 1996-07-25 1998-09-11 Synthelabo Derives de benzimidazole, leurs preparations et leurs applications en therapeutique

Also Published As

Publication number Publication date
TW448170B (en) 2001-08-01
AR023292A1 (es) 2002-09-04
AU1243399A (en) 1999-06-07
CO4990949A1 (es) 2000-12-26
JP2001523679A (ja) 2001-11-27
FR2771093A1 (fr) 1999-05-21
US6200991B1 (en) 2001-03-13
WO1999025710A1 (fr) 1999-05-27
EP1032569A1 (fr) 2000-09-06
ZA9810558B (en) 1999-05-18

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Legal Events

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TP Transmission of property
ST Notification of lapse