FR2453851A1 - Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant - Google Patents

Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant

Info

Publication number
FR2453851A1
FR2453851A1 FR8013297A FR8013297A FR2453851A1 FR 2453851 A1 FR2453851 A1 FR 2453851A1 FR 8013297 A FR8013297 A FR 8013297A FR 8013297 A FR8013297 A FR 8013297A FR 2453851 A1 FR2453851 A1 FR 2453851A1
Authority
FR
France
Prior art keywords
prostaglandin
analogs
pharmaceutical compositions
compositions containing
alcohylaralcoycoycoycoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8013297A
Other languages
English (en)
Other versions
FR2453851B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of FR2453851A1 publication Critical patent/FR2453851A1/fr
Application granted granted Critical
Publication of FR2453851B1 publication Critical patent/FR2453851B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/02—Lithium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

L'INVENTION CONCERNE DE NOUVEAUX ANALOGUES DE LA PROSTAGLANDINE E. CES COMPOSES ONT LA FORMULE CI-DESSOUS, DANS LAQUELLE Y ET ZETHYLENE OU VINYLENE TRANS, RH, ALCOYLE, ARALCOYLE, CYCLOALCOYLE, PHENYLE SUBSTITUE OU NON, CARBOXYALCOYLE, ALCOXYCARBONYLALCOYLE, HYDROXYALCOYLE, ALCOXYALCOYLE OU AMINOALCOYLE, RH, METHYLE OU ETHYLE, RLIAISON SIMPLE OU ALCOYLENE, RCYCLOALCOYLE SUBSTITUE OU NON PAR AU MOINS UN GROUPE ALCOYLE. APPLICATIONS PHARMACOLOGIQUES DANS LES DOMAINES HABITUELS POUR LES PROSTAGLANDINES. (CF DESSIN DANS BOPI)
FR8013297A 1977-09-16 1980-06-16 Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant Expired FR2453851B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52110504A JPS6022710B2 (ja) 1977-09-16 1977-09-16 プロスタグランジン類似化合物

Publications (2)

Publication Number Publication Date
FR2453851A1 true FR2453851A1 (fr) 1980-11-07
FR2453851B1 FR2453851B1 (fr) 1985-10-25

Family

ID=14537436

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7826303A Granted FR2403333A1 (fr) 1977-09-16 1978-09-13 Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant
FR8013297A Expired FR2453851B1 (fr) 1977-09-16 1980-06-16 Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7826303A Granted FR2403333A1 (fr) 1977-09-16 1978-09-13 Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant

Country Status (19)

Country Link
US (2) US4215142A (fr)
JP (1) JPS6022710B2 (fr)
AU (1) AU527940B2 (fr)
BE (1) BE870531A (fr)
CA (1) CA1119169A (fr)
CH (2) CH635318A5 (fr)
DE (2) DE2858094C2 (fr)
DK (3) DK405078A (fr)
FR (2) FR2403333A1 (fr)
GB (2) GB2006753B (fr)
HK (1) HK82185A (fr)
HU (1) HU182553B (fr)
IE (1) IE47439B1 (fr)
IT (2) IT1192580B (fr)
LU (1) LU80235A1 (fr)
MY (1) MY8600652A (fr)
NL (2) NL184467C (fr)
SG (1) SG58485G (fr)
ZA (1) ZA785230B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2834248A1 (de) * 1978-08-04 1980-02-28 Hoechst Ag Neue prostaglandinderivate in der delta 2-pgf tief 2 und delta 2-pge tief 2 -reihe
DE2913856A1 (de) * 1979-04-06 1980-10-23 Hoechst Ag Neue prostaglandinderivate in der 6-keto-pge tief 1 -reihe
EP0068871B1 (fr) * 1981-06-29 1986-05-07 Ono Pharmaceutical Co., Ltd. Analogues de prostaglandin
JPS58164512A (ja) * 1982-03-25 1983-09-29 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する肝臓疾患治療剤
JPS59163365A (ja) * 1983-03-08 1984-09-14 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物
DE3401542A1 (de) * 1984-01-18 1985-08-01 Merck Patent Gmbh, 6100 Darmstadt Schwefelhaltige 6-ketoprostaglandine
JPS60181068A (ja) * 1984-02-29 1985-09-14 Teijin Ltd ６−置換プロスタグランジンｅ↓１類およびその製造法
JPS6130554A (ja) * 1984-07-23 1986-02-12 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物のある特定の立体配置を有する異性体及びそれらを有効成分として含有する治療剤
US4755531A (en) * 1986-08-11 1988-07-05 Syntex (U.S.A.) Inc. Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents
DE3704825A1 (de) * 1987-02-16 1988-08-25 Froelich Juergen Prostaglandin e1-derivate als pharmazeutische wirkstoffe und diese verbindungen enthaltende arzneimittel insbesondere zur transkutanen anwendung
US5219885A (en) * 1987-02-16 1993-06-15 Froelich Juergen Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration
DE3708537A1 (de) * 1987-03-13 1988-09-22 Schering Ag 6-oxoprostaglandin-e-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
JPS63202544U (fr) * 1987-06-22 1988-12-27
EP0379242B1 (fr) * 1989-01-10 1994-03-30 Schön B.V. Jalousie pliante à double paroi
US5234954A (en) * 1989-07-27 1993-08-10 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of hyperlipidemia with 15-keto-prostaglandin compounds
US6576663B2 (en) 1999-12-22 2003-06-10 Alcon, Inc. 6-Keto prostaglandin F1α and analogs for treating dry eye
EP2516412A4 (fr) * 2009-12-18 2013-05-29 Apotex Pharmachem Inc Procédés de purification du lubiprostone

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2702553A1 (de) * 1976-02-04 1977-08-18 Upjohn Co Neue prostaglandinderivate mit 9-deoxy-6,9-epoxy-funktion
DE2753986A1 (de) * 1976-12-30 1978-07-06 Upjohn Co Prostaglandin e-artige derivate und analoga mit 6-ketofunktion und verfahren zu deren herstellung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4034003A (en) * 1974-04-11 1977-07-05 Ono Pharmaceutical Co., Ltd. 15-Cycloalkyl-prostaglandins
US4124601A (en) * 1976-12-30 1978-11-07 The Upjohn Company Certain 5-halo-6,9α-epoxy-14-bromo(or chloro)-PGF1 compounds
US4171447A (en) * 1976-12-30 1979-10-16 The Upjohn Company Tri-halo prostaglandin intermediates

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2702553A1 (de) * 1976-02-04 1977-08-18 Upjohn Co Neue prostaglandinderivate mit 9-deoxy-6,9-epoxy-funktion
DE2753986A1 (de) * 1976-12-30 1978-07-06 Upjohn Co Prostaglandin e-artige derivate und analoga mit 6-ketofunktion und verfahren zu deren herstellung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/76 *

Also Published As

Publication number Publication date
IT8619809A0 (it) 1986-03-19
FR2403333A1 (fr) 1979-04-13
US4215142A (en) 1980-07-29
NL184467C (nl) 1989-08-01
ZA785230B (en) 1979-08-29
JPS5444639A (en) 1979-04-09
CH638492A5 (fr) 1983-09-30
GB2079268B (en) 1982-08-11
DK405078A (da) 1979-03-17
CA1119169A (fr) 1982-03-02
NL7809368A (nl) 1979-03-20
AU527940B2 (en) 1983-03-31
GB2079268A (en) 1982-01-20
IE781857L (en) 1979-03-16
FR2453851B1 (fr) 1985-10-25
CH635318A5 (fr) 1983-03-31
GB2006753B (en) 1982-08-04
HU182553B (en) 1984-02-28
DK620189D0 (da) 1989-12-08
IT1192580B (it) 1988-04-20
DK620289D0 (da) 1989-12-08
IE47439B1 (en) 1984-03-21
DE2840032A1 (de) 1979-03-29
IT1213051B (it) 1989-12-07
NL8203068A (nl) 1982-12-01
MY8600652A (en) 1986-12-31
HK82185A (en) 1985-11-01
GB2006753A (en) 1979-05-10
DK620289A (da) 1989-12-08
JPS6022710B2 (ja) 1985-06-03
IT7827773A0 (it) 1978-09-15
DE2858094C2 (de) 1986-03-06
FR2403333B1 (fr) 1982-05-07
LU80235A1 (fr) 1979-06-01
DK620189A (da) 1989-12-08
US4278688A (en) 1981-07-14
NL184467B (nl) 1989-03-01
BE870531A (fr) 1979-03-15
AU3988678A (en) 1980-03-20
DE2840032C2 (de) 1983-12-22
SG58485G (en) 1986-08-01

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