FR2077455A1 - 5-haloveratryl-4-aminoquinoles - antimalarials amoebicides anthelmintics anticoccidials - Google Patents

5-haloveratryl-4-aminoquinoles - antimalarials amoebicides anthelmintics anticoccidials

Info

Publication number
FR2077455A1
FR2077455A1 FR6930068A FR6930068A FR2077455A1 FR 2077455 A1 FR2077455 A1 FR 2077455A1 FR 6930068 A FR6930068 A FR 6930068A FR 6930068 A FR6930068 A FR 6930068A FR 2077455 A1 FR2077455 A1 FR 2077455A1
Authority
FR
France
Prior art keywords
haloveratryl
aminoquinoles
anticoccidials
amoebicides
antimalarials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6930068A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR6930068A priority Critical patent/FR2077455A1/en
Publication of FR2077455A1 publication Critical patent/FR2077455A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Title cpds. are of formula: (where R is H, alkyl, Ph or halogen; R1 is H, alkyl, aryl; R2 is H or one or more of halogens, alkyl, alkoxy or NO2; R3 is H or alkyl; R4 is Me, Et or Pr; A is F, Cl or Br). They are prepd. by the reaction of the appropriate 4-haloquinoline with a 4-amino-5-halo verastrol.
FR6930068A 1969-09-03 1969-09-03 5-haloveratryl-4-aminoquinoles - antimalarials amoebicides anthelmintics anticoccidials Withdrawn FR2077455A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6930068A FR2077455A1 (en) 1969-09-03 1969-09-03 5-haloveratryl-4-aminoquinoles - antimalarials amoebicides anthelmintics anticoccidials

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6930068A FR2077455A1 (en) 1969-09-03 1969-09-03 5-haloveratryl-4-aminoquinoles - antimalarials amoebicides anthelmintics anticoccidials

Publications (1)

Publication Number Publication Date
FR2077455A1 true FR2077455A1 (en) 1971-10-29

Family

ID=9039690

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6930068A Withdrawn FR2077455A1 (en) 1969-09-03 1969-09-03 5-haloveratryl-4-aminoquinoles - antimalarials amoebicides anthelmintics anticoccidials

Country Status (1)

Country Link
FR (1) FR2077455A1 (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998013350A1 (en) * 1996-09-25 1998-04-02 Zeneca Limited Qinoline derivatives inhibiting the effect of growth factors such as vegf
US6291455B1 (en) 1996-03-05 2001-09-18 Zeneca Limited 4-anilinoquinazoline derivatives
US6638945B1 (en) 1999-05-08 2003-10-28 Astrazeneca Ab Quinoline derivatives as inhibitors of MEK enzymes
US6809106B1 (en) 1999-05-08 2004-10-26 Astrazeneca Ab Quinoline derivatives as inhibitors of MEK enzymes
WO2006034235A2 (en) * 2004-09-20 2006-03-30 Serenex, Inc. Substituted quinoline and quinazoline inhibitors of quinone reductase 2
US7067532B2 (en) 2000-11-02 2006-06-27 Astrazeneca Substituted quinolines as antitumor agents
US7160889B2 (en) 2000-04-07 2007-01-09 Astrazeneca Ab Quinazoline compounds
US7173136B2 (en) 2002-11-02 2007-02-06 Astrazeneca Ab 3-Cyano-quinoline derivatives
US7173135B2 (en) 2002-07-09 2007-02-06 Astrazeneca Ab Substituted 3-cyanoquinolines as MEK inhibitors
US7253184B2 (en) 2000-11-02 2007-08-07 Astrazeneca Ab 4-Substituted quinolines as antitumor agents
US7381824B2 (en) 2003-12-23 2008-06-03 Agouron Pharmaceuticals, Inc. Quinoline derivatives

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6291455B1 (en) 1996-03-05 2001-09-18 Zeneca Limited 4-anilinoquinazoline derivatives
WO1998013350A1 (en) * 1996-09-25 1998-04-02 Zeneca Limited Qinoline derivatives inhibiting the effect of growth factors such as vegf
US6809097B1 (en) 1996-09-25 2004-10-26 Zeneca Limited Quinoline derivatives inhibiting the effect of growth factors such as VEGF
US6638945B1 (en) 1999-05-08 2003-10-28 Astrazeneca Ab Quinoline derivatives as inhibitors of MEK enzymes
US6809106B1 (en) 1999-05-08 2004-10-26 Astrazeneca Ab Quinoline derivatives as inhibitors of MEK enzymes
US7160889B2 (en) 2000-04-07 2007-01-09 Astrazeneca Ab Quinazoline compounds
US7067532B2 (en) 2000-11-02 2006-06-27 Astrazeneca Substituted quinolines as antitumor agents
US7253184B2 (en) 2000-11-02 2007-08-07 Astrazeneca Ab 4-Substituted quinolines as antitumor agents
US7402583B2 (en) 2000-11-02 2008-07-22 Astrzenca Ab Substituted quinolines as antitumor agents
US7504416B2 (en) 2000-11-02 2009-03-17 Astrazeneca Ab 4-substituted quinolines as antitumor agents
US7173135B2 (en) 2002-07-09 2007-02-06 Astrazeneca Ab Substituted 3-cyanoquinolines as MEK inhibitors
US7173136B2 (en) 2002-11-02 2007-02-06 Astrazeneca Ab 3-Cyano-quinoline derivatives
US7381824B2 (en) 2003-12-23 2008-06-03 Agouron Pharmaceuticals, Inc. Quinoline derivatives
US7923457B2 (en) 2003-12-23 2011-04-12 Agouron Pharmaceuticals Inc. Quinoline derivatives
WO2006034235A3 (en) * 2004-09-20 2006-12-21 Serenex Inc Substituted quinoline and quinazoline inhibitors of quinone reductase 2
WO2006034235A2 (en) * 2004-09-20 2006-03-30 Serenex, Inc. Substituted quinoline and quinazoline inhibitors of quinone reductase 2

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Legal Events

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