FI65439C - Foerfarande foer framstaellning av nitrosoureaderivat med anti-turmoeraktivitet - Google Patents

Foerfarande foer framstaellning av nitrosoureaderivat med anti-turmoeraktivitet Download PDF

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Publication number
FI65439C
FI65439C FI782215A FI782215A FI65439C FI 65439 C FI65439 C FI 65439C FI 782215 A FI782215 A FI 782215A FI 782215 A FI782215 A FI 782215A FI 65439 C FI65439 C FI 65439C
Authority
FI
Finland
Prior art keywords
chloroethyl
mixture
glucopyranosyl
methanol
treated
Prior art date
Application number
FI782215A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI782215A (fi
FI65439B (fi
Inventor
Kenji Tsujihara
Masakatsu Ozeki
Yoshihisa Arai
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9167477A external-priority patent/JPS5427526A/ja
Priority claimed from JP11425977A external-priority patent/JPS5448717A/ja
Priority claimed from JP1122578A external-priority patent/JPS54103826A/ja
Priority claimed from JP5856078A external-priority patent/JPS6026120B2/ja
Priority claimed from JP6345978A external-priority patent/JPS5919555B2/ja
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of FI782215A publication Critical patent/FI782215A/fi
Application granted granted Critical
Publication of FI65439B publication Critical patent/FI65439B/fi
Publication of FI65439C publication Critical patent/FI65439C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/66—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to halogen atoms or to nitro or nitroso groups
    • C07C275/68—N-nitroso ureas

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI782215A 1977-07-29 1978-07-11 Foerfarande foer framstaellning av nitrosoureaderivat med anti-turmoeraktivitet FI65439C (fi)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP9167477 1977-07-29
JP9167477A JPS5427526A (en) 1977-07-29 1977-07-29 Nitrosourea compounds and their preparation
JP11425977 1977-09-22
JP11425977A JPS5448717A (en) 1977-09-22 1977-09-22 Nitrosourea compounds and their preparation
JP1122578 1978-02-02
JP1122578A JPS54103826A (en) 1978-02-02 1978-02-02 Nitrosourea derivative and its preparation
JP5856078 1978-05-16
JP5856078A JPS6026120B2 (ja) 1978-05-16 1978-05-16 ニトロソ尿素誘導体の製法
JP6345978A JPS5919555B2 (ja) 1978-05-26 1978-05-26 ニトロソ尿素透導体及びその製法
JP6345978 1978-05-26

Publications (3)

Publication Number Publication Date
FI782215A FI782215A (fi) 1979-01-30
FI65439B FI65439B (fi) 1984-01-31
FI65439C true FI65439C (fi) 1984-05-10

Family

ID=27519266

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782215A FI65439C (fi) 1977-07-29 1978-07-11 Foerfarande foer framstaellning av nitrosoureaderivat med anti-turmoeraktivitet

Country Status (21)

Country Link
US (1) US4182757A (nl)
AR (1) AR219331A1 (nl)
AT (1) AT360553B (nl)
AU (1) AU525239B2 (nl)
BE (1) BE869352A (nl)
CA (1) CA1097624A (nl)
CH (1) CH636626A5 (nl)
CS (1) CS216918B2 (nl)
DE (2) DE2858078C2 (nl)
DK (1) DK331978A (nl)
FI (1) FI65439C (nl)
FR (4) FR2403994A1 (nl)
GB (1) GB2002370B (nl)
HU (1) HU176891B (nl)
IT (1) IT1160450B (nl)
NL (1) NL7808036A (nl)
PH (1) PH13936A (nl)
PL (1) PL111784B1 (nl)
PT (1) PT68359A (nl)
SE (1) SE435501B (nl)
SU (1) SU908247A3 (nl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4241052A (en) * 1978-06-10 1980-12-23 Tanabe Seiyaku Co., Ltd. Novel nitrosourea compounds and process for preparing the same
US4241053A (en) * 1978-08-25 1980-12-23 Tanabe Seiyaku Co., Ltd. Novel nitrosourea compounds and process for preparing the same
EP0058665B1 (en) * 1980-05-09 1986-02-26 LEFFLER, Hakon Carbohydrate derivatives for inhibiting bacterial adherence
JPS5775993A (en) * 1980-10-30 1982-05-12 Tetsuo Suami Novel nitrosourea derivative and its preparation
JPS57165398A (en) * 1981-04-02 1982-10-12 Tanabe Seiyaku Co Ltd Nitrosourea derivative and its preparation
JPS5815951A (ja) * 1981-07-21 1983-01-29 Kureha Chem Ind Co Ltd ニトロソウレア誘導体、その製法及びこの誘導体を含有する薬剤
US4656259A (en) * 1983-06-29 1987-04-07 Institut Organicheskoy Khimii Akademii Nauk Kirgizskoi Method for preparing N-alkyl-N'-glycosyl-N-nitrosourea
DE3436670A1 (de) * 1984-10-05 1986-04-10 Kangaroos U.S.A. Inc., Maryland Heights, Mo. Fussstuetze fuer fussbekleidung, insbesondere fuer schuhe
US8853284B2 (en) 2008-06-02 2014-10-07 Honeywell International Inc. Wax dispersion formulations, method of producing same, and uses
US10941111B2 (en) * 2018-10-16 2021-03-09 Purdue Research Foundation On-demand rapid synthesis of lomustine under continuous flow conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577406A (en) * 1968-05-23 1971-05-04 Upjohn Co Process for preparing the antibiotic streptozotocin
JPS4843333B1 (nl) * 1970-04-25 1973-12-18
JPS5230491B2 (nl) * 1974-07-05 1977-08-09
JPS5126876A (en) * 1974-08-08 1976-03-05 Suami T Shinkina nitorosonyosojudotaino seizohoho
GB1507099A (en) * 1974-08-08 1978-04-12 Suami T Nitrosourea derivatives
US3940383A (en) * 1974-12-12 1976-02-24 Stanford Research Institute Streptozotocin analogs

Also Published As

Publication number Publication date
FR2485541B1 (nl) 1986-06-06
FR2499577B1 (nl) 1984-07-13
SU908247A3 (ru) 1982-02-23
GB2002370B (en) 1982-03-03
FR2485541A1 (nl) 1981-12-31
DE2858078C2 (de) 1983-12-15
HU176891B (en) 1981-05-28
FR2475040A1 (nl) 1981-08-07
PH13936A (en) 1980-11-04
CS216918B2 (en) 1982-12-31
DE2832127C2 (de) 1983-07-28
FR2403994A1 (fr) 1979-04-20
PT68359A (en) 1978-08-01
GB2002370A (en) 1979-02-21
FI782215A (fi) 1979-01-30
AT360553B (de) 1981-01-26
CH636626A5 (de) 1983-06-15
AR219331A1 (es) 1980-08-15
ATA546178A (de) 1980-06-15
SE7808162L (sv) 1979-01-30
NL7808036A (nl) 1979-01-31
DE2832127A1 (de) 1979-02-08
SE435501B (sv) 1984-10-01
PL111784B1 (en) 1980-09-30
DK331978A (da) 1979-01-30
CA1097624A (en) 1981-03-17
FI65439B (fi) 1984-01-31
FR2499577A1 (fr) 1982-08-13
US4182757A (en) 1980-01-08
AU3849178A (en) 1980-02-07
FR2475040B1 (nl) 1984-11-16
IT7868797A0 (it) 1978-07-27
PL208701A1 (pl) 1979-06-04
AU525239B2 (en) 1982-10-28
BE869352A (fr) 1979-01-29
IT1160450B (it) 1987-03-11

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MM Patent lapsed

Owner name: TANABE SEIYAKU CO. LTD.