FI49503C - Analogiförfarande för framställning av 1,2,3,4-tetrahydro-4-fenyl-isok inolinderivat. - Google Patents

Analogiförfarande för framställning av 1,2,3,4-tetrahydro-4-fenyl-isok inolinderivat.

Info

Publication number
FI49503C
FI49503C FI703519A FI351970A FI49503C FI 49503 C FI49503 C FI 49503C FI 703519 A FI703519 A FI 703519A FI 351970 A FI351970 A FI 351970A FI 49503 C FI49503 C FI 49503C
Authority
FI
Finland
Prior art keywords
tetrahydro
preparation
analogous process
phenylisoquinoline derivatives
phenylisoquinoline
Prior art date
Application number
FI703519A
Other languages
English (en)
Finnish (fi)
Other versions
FI49503B (sv
Inventor
Jr Alfred Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of FI49503B publication Critical patent/FI49503B/fi
Publication of FI49503C publication Critical patent/FI49503C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI703519A 1970-01-06 1970-12-31 Analogiförfarande för framställning av 1,2,3,4-tetrahydro-4-fenyl-isok inolinderivat. FI49503C (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (2)

Publication Number Publication Date
FI49503B FI49503B (sv) 1975-04-01
FI49503C true FI49503C (sv) 1975-07-10

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
FI703519A FI49503C (sv) 1970-01-06 1970-12-31 Analogiförfarande för framställning av 1,2,3,4-tetrahydro-4-fenyl-isok inolinderivat.

Country Status (19)

Country Link
JP (1) JPS5515476B1 (sv)
AT (1) AT303041B (sv)
BE (1) BE761219A (sv)
CA (1) CA999866A (sv)
CH (2) CH527194A (sv)
DE (1) DE2062001C2 (sv)
DK (1) DK125021B (sv)
ES (1) ES387016A1 (sv)
FI (1) FI49503C (sv)
FR (1) FR2081412B1 (sv)
GB (1) GB1335261A (sv)
IE (1) IE34859B1 (sv)
IL (1) IL35916A (sv)
NL (1) NL171444C (sv)
NO (1) NO135315C (sv)
PH (1) PH9682A (sv)
SE (3) SE368401B (sv)
YU (1) YU33660B (sv)
ZA (1) ZA708590B (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
EP1246806B1 (en) 1999-11-03 2008-02-27 AMR Technology, Inc. Arly- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
CN100436420C (zh) * 1999-11-03 2008-11-26 Amr科技公司 4-苯基取代的四氢异喹啉及其用于制备药物的用途
EP1113007A1 (en) 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
EP1299393A2 (en) 2000-07-11 2003-04-09 Bristol-Myers Squibb Pharma Company 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
MX2007000428A (es) 2004-07-15 2008-03-05 Amr Technology Inc Tetrahidroisoquinolinas sustituidas con arilo y heteroarilo y uso de las mismas para bloquear la captacion de norepinefrina, dopamina y serotonina.
DK1899334T3 (da) * 2005-06-17 2008-11-24 Janssen Pharmaceutica Nv Naphthyridinforbindelser
CN101495184A (zh) 2005-07-15 2009-07-29 Amr科技公司 芳基和杂芳基取代的四氢苯并氮杂及其在阻断去甲肾上腺素多巴胺和血清素的重摄取中的应用
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
PE20120373A1 (es) 2009-05-12 2012-05-17 Albany Molecular Res Inc 7-([1,2,4]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
AU2010247849B2 (en) 2009-05-12 2015-11-19 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
PH9682A (en) 1976-02-10
IE34859L (en) 1971-07-06
NL171444B (nl) 1982-11-01
AT303041B (de) 1972-11-10
IE34859B1 (en) 1975-09-03
DK125021B (da) 1972-12-18
IL35916A0 (en) 1971-02-25
YU33660B (en) 1977-12-31
IL35916A (en) 1973-11-28
SE368401B (sv) 1974-07-01
NO135315B (sv) 1976-12-13
JPS5515476B1 (sv) 1980-04-23
ES387016A1 (es) 1976-05-01
CA999866A (en) 1976-11-16
FI49503B (sv) 1975-04-01
FR2081412A1 (sv) 1971-12-03
NL7018956A (sv) 1971-07-08
SE386672B (sv) 1976-08-16
GB1335261A (en) 1973-10-24
CH527194A (de) 1972-08-31
SE399879B (sv) 1978-03-06
BE761219A (fr) 1971-07-05
NO135315C (sv) 1977-03-23
DE2062001A1 (de) 1971-07-15
CH538477A (de) 1973-06-30
ZA708590B (en) 1971-09-29
NL171444C (nl) 1983-04-05
YU1971A (en) 1977-06-30
DE2062001C2 (de) 1986-10-16
FR2081412B1 (sv) 1974-04-12

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