ES456252A1 - Anti-microbial bis-pyridinium compounds - Google Patents
Anti-microbial bis-pyridinium compoundsInfo
- Publication number
- ES456252A1 ES456252A1 ES456252A ES456252A ES456252A1 ES 456252 A1 ES456252 A1 ES 456252A1 ES 456252 A ES456252 A ES 456252A ES 456252 A ES456252 A ES 456252A ES 456252 A1 ES456252 A1 ES 456252A1
- Authority
- ES
- Spain
- Prior art keywords
- microbial
- bis
- image
- compounds
- pyridinium compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The compounds of formulae I and II in which the symbols have the meaning given in Claim 1 are prepared by reaction of 2 mole parts of a compound < IMAGE > or, respectively, < IMAGE >, with one mole part of a compound Z-Y-Z or, respectively, < IMAGE >, Z being an atom or radical which splits in the form of an anion which is then the anion A. The latter can be exchanged by metathesis against other anions A. The compounds thus prepared have antibacterial, fungicidal and viricidal properties and can be used, for example, in medicine, as disinfectants and as antimicrobial agents.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66112876A | 1976-02-25 | 1976-02-25 | |
| US66110176A | 1976-02-25 | 1976-02-25 | |
| US72131576A | 1976-09-07 | 1976-09-07 | |
| US05/734,729 US4107313A (en) | 1976-02-25 | 1976-10-22 | α,α-Bis-[4-(R-amino)-1-pyridinium]xylenes and antibacterial and antifungal uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES456252A1 true ES456252A1 (en) | 1978-02-01 |
Family
ID=27505307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES456252A Expired ES456252A1 (en) | 1976-02-25 | 1977-02-24 | Anti-microbial bis-pyridinium compounds |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS6033108B2 (en) |
| AR (2) | AR214876A1 (en) |
| AT (1) | AT355571B (en) |
| AU (1) | AU510149B2 (en) |
| BE (1) | BE851807A (en) |
| CA (1) | CA1073911A (en) |
| CH (1) | CH620907A5 (en) |
| DE (1) | DE2708331A1 (en) |
| DK (1) | DK147638C (en) |
| ES (1) | ES456252A1 (en) |
| FI (1) | FI66850C (en) |
| FR (1) | FR2342286A1 (en) |
| GB (1) | GB1533952A (en) |
| HK (1) | HK67484A (en) |
| IE (1) | IE45336B1 (en) |
| IL (1) | IL51520A (en) |
| LU (1) | LU76837A1 (en) |
| MX (1) | MX5132E (en) |
| NL (1) | NL186086C (en) |
| NO (2) | NO148779C (en) |
| PH (2) | PH22315A (en) |
| PT (1) | PT66224B (en) |
| SE (1) | SE432421B (en) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE32300E (en) * | 1979-08-13 | 1986-12-02 | Sterling Drug Inc. | Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant compositions and method of use thereof |
| US4420484A (en) | 1979-08-13 | 1983-12-13 | Sterling Drug Inc. | Basic amino or ammonium antimicrobial agent-polyethylene glycol ester surfactant-betaine and/or amine oxide surfactant compositions and method of use therof |
| DE19647402A1 (en) * | 1996-11-15 | 1998-05-20 | Hoechst Schering Agrevo Gmbh | Substituted nitrogen heterocycles, processes for their preparation and their use as pesticides |
| DE19647317A1 (en) * | 1996-11-15 | 1998-05-20 | Hoechst Schering Agrevo Gmbh | Substituted nitrogen heterocycles, processes for their preparation and their use as pesticides |
| DE19647413A1 (en) * | 1996-11-15 | 1998-05-20 | Hoechst Schering Agrevo Gmbh | Substituted nitrogen heterocycles, processes for their preparation and their use as pesticides |
| DE10005853C1 (en) * | 2000-02-10 | 2002-02-07 | Schuelke & Mayr Gmbh | Process for the preparation of bis- (4-amino-1-pyridinium) alkanes |
| DE10205883A1 (en) * | 2002-02-13 | 2003-08-21 | Schuelke & Mayr Gmbh | Aqueous antiseptic based on bispyridiniumalkanes |
| TWI278315B (en) * | 2003-06-13 | 2007-04-11 | Ind Tech Res Inst | A compound having anti-virus activity |
| ES2237332B1 (en) * | 2004-01-14 | 2006-11-01 | Consejo Sup. Investig. Cientificas | DERIVATIVES OF PIRIDINIO AND QUINOLINIO. |
| DE102005002645A1 (en) * | 2005-01-19 | 2006-07-20 | Schülke & Mayr GmbH | Alcoholic compositions for disinfection |
| DE102005002644A1 (en) * | 2005-01-19 | 2006-07-20 | Schülke & Mayr GmbH | Compositions for hygienic hand disinfection and disinfecting hand washing |
| DE102005002643B4 (en) * | 2005-01-19 | 2007-11-22 | Schülke & Mayr GmbH | Compositions for hygienic hand disinfection and disinfecting hand washing |
| DE102005045145A1 (en) * | 2005-09-15 | 2007-03-29 | Schülke & Mayr GmbH | Use of octenidine dihydrochloride in semisolid preparations |
| DE102005063375A1 (en) * | 2005-09-15 | 2007-04-19 | Schülke & Mayr GmbH | Antimicrobial preparations containing octenidine dihydrochloride encapsulated in liposomes |
| DE102005048132A1 (en) * | 2005-10-06 | 2007-04-12 | Bayer Innovation Gmbh | Process for producing antimicrobial plastic compositions |
| DE102005048131A1 (en) * | 2005-10-06 | 2007-04-12 | Bayer Innovation Gmbh | Antimicrobial plastic composition with low elution rate and long efficacy |
| DE102006012991A1 (en) | 2006-03-22 | 2007-10-11 | Bayer Innovation Gmbh | Method and device for optically reading information |
| DE102006051891A1 (en) * | 2006-10-31 | 2008-05-08 | Schülke & Mayr GmbH | Antimicrobial composition containing Bispyridiniumalkan |
| DE102008011691A1 (en) | 2008-02-28 | 2009-09-10 | Schülke & Mayr GmbH | Stabilized antimicrobial composition containing bispyridiniumalkane |
| DE102009049504A1 (en) | 2009-10-15 | 2011-04-21 | Schülke & Mayr GmbH | Wound and mucous membrane antiseptic based on bispyridiniumalkanes |
| DE102010022367A1 (en) | 2010-04-20 | 2011-10-20 | Klosterfrau Berlin Gmbh | Pharmaceutical composition in form of lubricating agent or gel used for treating and preventing infections and pain associated with catheterization comprises octenidine or its salts and local anesthetic |
| EP2384733B1 (en) * | 2010-05-07 | 2016-07-27 | Ivoclar Vivadent AG | Antimicrobial dental materials |
| DE102010025932A1 (en) | 2010-07-02 | 2012-01-05 | Schülke & Mayr GmbH | Antiseptic based on bispyridiniumalkanes |
| DE102011077432A1 (en) * | 2011-06-10 | 2012-12-13 | Schülke & Mayr GmbH | Use of bispyridiniumalkanes to kill spores |
| DE102012215511A1 (en) | 2012-08-31 | 2014-06-12 | Schülke & Mayr GmbH | Process for the preparation of a semi-solid preparation containing bispyridiniumalkane |
| DE102013223657A1 (en) | 2013-11-20 | 2015-05-21 | Schülke & Mayr GmbH | Kit for the production of Bispyridiniumalkan containing foams |
| DE102014107413A1 (en) | 2014-05-26 | 2015-11-26 | Schülke & Mayr GmbH | Kit for coloring of disinfected areas of a surface |
| DE102014107412A1 (en) | 2014-05-26 | 2015-12-17 | Schülke & Mayr GmbH | Colored disinfecting preparation based on bispyridiniumalkane |
| DE102014115080A1 (en) | 2014-10-16 | 2016-04-21 | Schülke & Mayr GmbH | Use of fatty acid esters to improve the antimicrobial effectiveness of an alcoholic disinfectant |
| CA3072030A1 (en) * | 2017-08-21 | 2019-02-28 | Dishman Carbogen Amcis Ltd. | Octenidine based compounds |
| EP3771339A1 (en) * | 2019-07-29 | 2021-02-03 | The Procter & Gamble Company | Disinfectant composition |
| EP3771337A1 (en) | 2019-07-29 | 2021-02-03 | The Procter & Gamble Company | Antimicrobial composition |
| EP3771741A1 (en) | 2019-07-29 | 2021-02-03 | The Procter & Gamble Company | Fabric treatment |
| EP3771338A1 (en) | 2019-07-29 | 2021-02-03 | The Procter & Gamble Company | Acidic antimicrobial composition |
| EP3771770A1 (en) | 2019-07-29 | 2021-02-03 | The Procter & Gamble Company | Antimicrobial freshening compositions |
| EP3816272B1 (en) | 2019-10-31 | 2023-11-01 | The Procter & Gamble Company | Fabric care composition |
| CN114989076A (en) * | 2022-06-07 | 2022-09-02 | 八叶草健康产业研究院(厦门)有限公司 | Preparation method of octenidine base |
-
1977
- 1977-02-11 GB GB5784/77A patent/GB1533952A/en not_active Expired
- 1977-02-21 PH PH19473A patent/PH22315A/en unknown
- 1977-02-22 IL IL51520A patent/IL51520A/en unknown
- 1977-02-23 FI FI770593A patent/FI66850C/en not_active IP Right Cessation
- 1977-02-23 IE IE386/77A patent/IE45336B1/en unknown
- 1977-02-23 PT PT66224A patent/PT66224B/en unknown
- 1977-02-23 NL NLAANVRAGE7701965,A patent/NL186086C/en not_active IP Right Cessation
- 1977-02-23 AU AU22582/77A patent/AU510149B2/en not_active Expired
- 1977-02-23 MX MX775459U patent/MX5132E/en unknown
- 1977-02-24 NO NO770631A patent/NO148779C/en unknown
- 1977-02-24 LU LU76837A patent/LU76837A1/xx unknown
- 1977-02-24 AR AR266668A patent/AR214876A1/en active
- 1977-02-24 CA CA272,596A patent/CA1073911A/en not_active Expired
- 1977-02-24 ES ES456252A patent/ES456252A1/en not_active Expired
- 1977-02-24 CH CH233677A patent/CH620907A5/en not_active IP Right Cessation
- 1977-02-24 DK DK81277A patent/DK147638C/en not_active IP Right Cessation
- 1977-02-24 SE SE7702072A patent/SE432421B/en not_active IP Right Cessation
- 1977-02-25 FR FR7705621A patent/FR2342286A1/en active Granted
- 1977-02-25 JP JP52020130A patent/JPS6033108B2/en not_active Expired
- 1977-02-25 BE BE1007973A patent/BE851807A/en not_active IP Right Cessation
- 1977-02-25 DE DE19772708331 patent/DE2708331A1/en active Granted
- 1977-02-25 AT AT129777A patent/AT355571B/en not_active IP Right Cessation
- 1977-11-11 PH PH20428A patent/PH25097A/en unknown
-
1978
- 1978-01-04 AR AR270629A patent/AR218052A1/en active
-
1982
- 1982-09-28 NO NO823274A patent/NO150758C/en unknown
-
1984
- 1984-08-30 HK HK674/84A patent/HK67484A/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19981103 |