EP1150673A4 - Mono-acyloxy aralkyl neuromuscular relaxants - Google Patents

Mono-acyloxy aralkyl neuromuscular relaxants

Info

Publication number: EP1150673A4
Authority: EP; European Patent Office
Prior art keywords: acyloxy; aralkyl; mono; neuromuscular relaxants; relaxants
Prior art date: 1999-02-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP00904621A

Other languages

German (de)

French (fr)

Other versions

EP1150673A1 (en

Inventor

Chingmuh Lee

Laszlo Gyermek

Young-Moon Cho

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Newlaxant LLC

Original Assignee

Newlaxant LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-01

Filing date

2000-01-31

Publication date

2002-04-24

2000-01-31 Application filed by Newlaxant LLC filed Critical Newlaxant LLC

2001-11-07 Publication of EP1150673A1 publication Critical patent/EP1150673A1/en

2002-04-24 Publication of EP1150673A4 publication Critical patent/EP1150673A4/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Orthopedic Medicine & Surgery (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

EP00904621A 1999-02-01 2000-01-31 Mono-acyloxy aralkyl neuromuscular relaxants Withdrawn EP1150673A4 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11839299P	1999-02-01	1999-02-01
US118392P		1999-02-01
PCT/US2000/002228 WO2000044377A1 (en)	1999-02-01	2000-01-31	Mono-acyloxy aralkyl neuromuscular relaxants

Publications (2)

Publication Number	Publication Date
EP1150673A1 EP1150673A1 (en)	2001-11-07
EP1150673A4 true EP1150673A4 (en)	2002-04-24

Family

ID=22378296

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP00904621A Withdrawn EP1150673A4 (en)	1999-02-01	2000-01-31	Mono-acyloxy aralkyl neuromuscular relaxants

Country Status (21)

Country	Link
EP (1)	EP1150673A4 (en)
JP (1)	JP2002535366A (en)
KR (1)	KR20010108125A (en)
CN (1)	CN1338934A (en)
AR (1)	AR022472A1 (en)
AU (1)	AU2634900A (en)
BR (1)	BR0007863A (en)
CA (1)	CA2360790A1 (en)
CO (1)	CO5170470A1 (en)
CZ (1)	CZ20012780A3 (en)
HK (1)	HK1039455A1 (en)
HU (1)	HUP0200413A3 (en)
IL (1)	IL144249A0 (en)
MX (1)	MXPA01007783A (en)
NO (1)	NO20013741L (en)
NZ (1)	NZ513064A (en)
PE (1)	PE20001593A1 (en)
PL (1)	PL349099A1 (en)
TR (1)	TR200102196T2 (en)
WO (1)	WO2000044377A1 (en)
ZA (1)	ZA200105882B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0204087D0 (en) *	2002-02-21	2002-04-10	Legislator 1563 Ltd	Di-ester derivatives as short acting neuromuscular blockers

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2746964A (en) *	1953-11-02	1956-05-22	Lakeside Lab Inc	Dicarboxylic acid esters of nu-alkyl-3-hydroxypiperidine and salts thereof
AT292702B (en) *	1968-12-29	1971-09-10	Egyt Gyogyszervegyeszeti Gyar	Process for the preparation of new N-methyl-piperidine derivatives and the acid addition salts and the onium derivatives of these compounds
US5494898A (en) *	1991-02-13	1996-02-27	Ohmeda Pharmaceutical Products Division Inc.	Peptide skeletal muscle relaxants
US5990124A (en) *	1997-10-24	1999-11-23	Gyermek; Laszlo	Neuromuscular relaxants

2000
- 2000-01-31 MX MXPA01007783A patent/MXPA01007783A/en unknown
- 2000-01-31 AU AU26349/00A patent/AU2634900A/en not_active Abandoned
- 2000-01-31 CZ CZ20012780A patent/CZ20012780A3/en unknown
- 2000-01-31 EP EP00904621A patent/EP1150673A4/en not_active Withdrawn
- 2000-01-31 IL IL14424900A patent/IL144249A0/en unknown
- 2000-01-31 CA CA002360790A patent/CA2360790A1/en not_active Abandoned
- 2000-01-31 JP JP2000595680A patent/JP2002535366A/en not_active Withdrawn
- 2000-01-31 KR KR1020017009305A patent/KR20010108125A/en not_active Application Discontinuation
- 2000-01-31 CN CN00803305A patent/CN1338934A/en active Pending
- 2000-01-31 TR TR2001/02196T patent/TR200102196T2/en unknown
- 2000-01-31 WO PCT/US2000/002228 patent/WO2000044377A1/en active Search and Examination
- 2000-01-31 HU HU0200413A patent/HUP0200413A3/en unknown
- 2000-01-31 PL PL00349099A patent/PL349099A1/en not_active Application Discontinuation
- 2000-01-31 PE PE2000000069A patent/PE20001593A1/en not_active Application Discontinuation
- 2000-01-31 NZ NZ513064A patent/NZ513064A/en unknown
- 2000-01-31 BR BR0007863-8A patent/BR0007863A/en not_active IP Right Cessation
- 2000-02-01 CO CO00005913A patent/CO5170470A1/en not_active Application Discontinuation
- 2000-02-01 AR ARP000100432A patent/AR022472A1/en not_active Application Discontinuation
2001
- 2001-07-17 ZA ZA200105882A patent/ZA200105882B/en unknown
- 2001-07-31 NO NO20013741A patent/NO20013741L/en not_active Application Discontinuation
2002
- 2002-02-08 HK HK02100995.3A patent/HK1039455A1/en unknown

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
L. GYERMEK, C. LEE, N. NGUYEN: "Pharmacology of G-1-64, a new nondepolarizing neuromuscular blocking agent with rapid onset and short duration of action", ACTA ANAESTHESIOLOGICA SCANDINAVICA, XX, XX, vol. 43, no. 6, July 1999 (1999-07-01), pages 651 - 657, XP001056943, ISSN: 0001-5172 *

Also Published As

Publication number	Publication date
JP2002535366A (en)	2002-10-22
KR20010108125A (en)	2001-12-07
EP1150673A1 (en)	2001-11-07
WO2000044377A1 (en)	2000-08-03
PL349099A1 (en)	2002-07-01
HUP0200413A3 (en)	2002-11-28
HK1039455A1 (en)	2002-04-26
AR022472A1 (en)	2002-09-04
ZA200105882B (en)	2003-02-18
PE20001593A1 (en)	2001-01-16
CN1338934A (en)	2002-03-06
NO20013741L (en)	2001-09-19
TR200102196T2 (en)	2002-01-21
MXPA01007783A (en)	2002-08-20
NZ513064A (en)	2003-08-29
AU2634900A (en)	2000-08-18
BR0007863A (en)	2001-11-06
CO5170470A1 (en)	2002-06-27
NO20013741D0 (en)	2001-07-31
CZ20012780A3 (en)	2002-01-16
HUP0200413A2 (en)	2002-06-29
IL144249A0 (en)	2002-05-23
CA2360790A1 (en)	2000-08-03

Legal Events

Date	Code	Title	Description
2001-09-21	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2001-11-07	17P	Request for examination filed	Effective date: 20010903
2001-11-07	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2002-04-24	A4	Supplementary search report drawn up and despatched	Effective date: 20020311
2002-04-24	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
2002-04-24	RIC1	Information provided on ipc code assigned before grant	Free format text: 7A 61K 31/397 A, 7A 61K 31/403 B, 7A 61K 31/439 B, 7A 61K 31/4025 B, 7A 61K 31/4545 B, 7A 61K 31/55 B, 7C 07D 211/46 B, 7C 07D 223/08 B, 7C 07D 295/04 B
2002-08-28	17Q	First examination report despatched	Effective date: 20020710
2004-02-20	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2004-04-07	18D	Application deemed to be withdrawn	Effective date: 20031007
2008-09-05	REG	Reference to a national code	Ref country code: HK Ref legal event code: WD Ref document number: 1039455 Country of ref document: HK

Publication	Publication Date	Title
GB0029386D0 (en)	2001-01-17	Not known at present
GB9922662D0 (en)	1999-11-24	Handle-gripping
GB0029389D0 (en)	2001-01-17	Not known at present
GB9903584D0 (en)	1999-04-07	Modified calycins
GB2347186B (en)	2002-08-21	Improved nail
GB9901890D0 (en)	1999-03-17	Diffusere
GB2356125B (en)	2003-12-10	Ensilage
GB9912097D0 (en)	1999-07-28	E-Pen
GB9913742D0 (en)	1999-08-11	Horologe improvement
GB9914798D0 (en)	1999-08-25	Ensure
DE50012739D1 (en)	2006-06-14	Thermovliesstoff
PL349099A1 (en)	2002-07-01	Mono-acyloxy aralkyl neuromuscular relaxants
DE60004674D1 (en)	2003-09-25	Carbonylierungsreaktionen
GB0026973D0 (en)	2000-12-20	Thjreaded fasteners
HU0000970D0 (en)	2000-05-28	Rapid fastening set
TW433433U (en)	2001-05-01	Improved lampstand
EG22401A (en)	2003-01-29	Set 3c1-strong
CA86740S (en)	1999-05-28	Bus
GB9914563D0 (en)	1999-08-25	R s c
TW420259U (en)	2001-01-21	Connection strcutural improvement
GB9821854D0 (en)	1998-12-02	Nail hook
PL332809A1 (en)	2000-11-06	Console
LT97018A (en)	1998-08-25	The bread composition
LT97009A (en)	1998-08-25	The bread composition
PL343301A1 (en)	2001-04-23	Fastening means