EP0479825A4 - Therapeutic device for male sexual dysfunction - Google Patents

Therapeutic device for male sexual dysfunction

Info

Publication number
EP0479825A4
EP0479825A4 EP19900909436 EP90909436A EP0479825A4 EP 0479825 A4 EP0479825 A4 EP 0479825A4 EP 19900909436 EP19900909436 EP 19900909436 EP 90909436 A EP90909436 A EP 90909436A EP 0479825 A4 EP0479825 A4 EP 0479825A4
Authority
EP
European Patent Office
Prior art keywords
substantially rigid
penis
portions
penile
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900909436
Other versions
EP0479825A1 (en
Inventor
Darcy Lester Flynn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
S&T No 27 Pty Ltd
Original Assignee
S&T No 27 Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S&T No 27 Pty Ltd filed Critical S&T No 27 Pty Ltd
Publication of EP0479825A1 publication Critical patent/EP0479825A1/en
Publication of EP0479825A4 publication Critical patent/EP0479825A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/41Devices for promoting penis erection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/41Devices for promoting penis erection
    • A61F2005/414Devices for promoting penis erection by constricting means

Definitions

  • TITLE "THERAPEUTIC DEVICE FOR MALE SEXUAL DYSFUNCTION"
  • THIS INVENTION relates to a therapeutic device for male sexual dysfunction.
  • the device may also be used to enhance male sexual pleasure (e.g. by prolonging the male orgasm) .
  • a therapeutic device for male sexual dysfunction including:- a body having at least one rigid or semi ⁇ rigid portion and at least one malleable or deformable portion, so arranged that the body may be positioned around the base of a penis to apply a constriction force on at least one portion of the penis.
  • the body may comprise a closed loop.
  • the body may be substantially C-shaped and the free ends of the body may be releasably engageable.
  • the body comprises a core within a sheath of deformable material, the sheath preferably being formed of plastics material and may be skin coloured and have a textured finish.
  • the core may be formed from copper or stainless steel wire or strip, plastics strip or the like.
  • the rigid/semi-rigid portion(s) may be formed by placing a tubular portion about the wire or strip; or winding wire about the wire or strip; or by internal reinforcement or tempering of the wire or strip.
  • the malleable or deformable portion may comprise the wire or strip or a reduced thickness/diameter section of same.
  • the two rigid/semi-rigid portions are interconnected by the malleable/deformable positions, each of which may comprise textured sections to allow blood flow through the blood vessels just below the penile skin.
  • the textured sections may have diagonal, longitudinal or criss-crossed lines or slots.
  • the device may be substantially triangular in plan, although circular, oval, square, hexagonal or other shapes may be produced before the user forms the device to the desired shape to suit his needs.
  • the device may be circular or oval in cross-section; or substantially triangular in cross-section, tapering towards the front of the device.
  • FIG. 1 is a cross-sectional view of a male adult penis
  • FIG. 2 is a schematic side view showing the location of the device in use
  • FIG. 3 is a front view of the device;
  • FIG. 4 is a sectional front view of the device;
  • FIGS. 5 to 7 are sectional side views, taken on line A-A on FIG. 4 of alternative cross-sections of the device;
  • FIGS. 8 and 9 are respective sectional side views of further alternative cross-sections of the device; and FIGS. 10, 11 and 12 are front views of further alternative embodiments of the device.
  • the male penis 10 has the following areas relevant to the invention: corpora cavernosa 11, penile arteries 12, penile veins 13, urethra 14, corpus spongiosum 15 and skin 16.
  • the device 20 is positioned at the base of the penis 10 adjacent the scrotum 17.
  • the device 20, see FIGS. 3 and 4 is generally triangular in front view.
  • the top portion 21 has an enlarged central section 22 opposed to the generally U- or V-shaped bottom portion 23.
  • the two side portions 24 have enlarged sections 25, 26 which have criss-cross slots or grooves 27 (see FIGS. 5 to 7) which allow blood flow through the blood vessels under the skin 16 of the penis 10 when the device 20 is in use.
  • the central portion 22 has a pair of "lips" 28, 29 which apply spaced pressure to the top of the penis 10.
  • the device 20 has a core 30 of copper or stainless steel wire which is circular in section 31 in the central section 24 of the top portion and in the bottom portion 23, so arranged that these are rigid or substantially rigid.
  • the remaining portions 32 of the core are flattened to form a thin-section strip which is malleable or deformable so that the shape of the device 20 can be changed as hereinafter described.
  • the core 30 is enclosed within a deformable plastic sheath 33 which is skin coloured (in a range of skin tones) and have a textured surface or "skin").
  • the user positions the device as shown in FIG. 2. If the dysfunction to be overcome is the problem of achieving and/or maintaining a penile erection, he deforms the side portion 24 so that the central section 22 (and its lips 28, 29) apply a pressure on the top of the penis 10 to constrict the flow through the penile veins 13 (including the deep Dorsal vein). When the flow through the arteries 12 exceeds the flow through the veins 13, erection will be achieved and maintained. As the bottom portion 23 does not constrict the urethra 14 (see FIG. 10), ejaculation can occur normally.
  • the enlarged sections 25, 26 of the side portions 24 are moved inwardly to constrict the arterial blood flow so that the veneous blood flow will enable the penis to become flaccid after erection.
  • the bottom portion 23 is deformed to apply a constriction on the urethra 14. As blood can flow through the blood vessels under the penile skin 16, penile feeling is not lost.
  • the cross-section of the devices 20A, 20B, 20C may be generally rectangulr (FIG. 5), circular or oval (FIG. 6) and triangular or tapered (FIG. 7).
  • the lines or slots on the enlarged sections 25, 26 may be diagonal (27A) or longitudinal (27B).
  • the device 20D has a substantially right-angled triangular cross-section tapering from a back wall 35 which would engage the user's body 18 and tapering to a "nose" 36 a small distance along the shaft 19 of the penis 10.
  • the core 30D is formed by copper or stainless steel wire and the rigid/semi-rigid sectin 31D are formed by winding wire around the core 30D, where the core forms the malleable section 32D.
  • the device 20E has an oval cross-section with a core 30E formed of plastics (e.g. nylon, polyethylene) strip 32E where the enlarged sections 3IE are of increased thickness and may be impregnated with glass reinforcing fibres.
  • FIG. 10 shows an alternative embodiment of the device 20F which does not have the enlarged sections 25, 26 on its side portion 24F and the penis 10 is shown in dashed lines to show how the device can constrict the penile veins 13, while leaving the penile arteries 12 and urethra 14 unconstricted where the user has difficulty achieving and/or maintaining an erection.
  • FIG. 11 shows a further embodiment of the device 20G which is more circular in front view.
  • FIG. 12 shows a still further embodiment where the device 2OH does not comprise a closed loop but is substantially C-shaped.
  • the free ends of the device 20H may be releasably secured together to form a closed loop.
  • the user has established the best shape of the device for his needs, e.g. to achieve and maintain an erection without discomfort, he will leave the shape of the deviced fixed and it will be ready for use the next time the sexual act is to be consumated.
  • the sheath is preferably skin coloured and textured, it is unobtrusive and a sexual partner may not be aware that it is in place.
  • the device can be easily fitted before the sexual act and removed when no longer required. It's inert material sheath 33 can be easily cleaned between use.
  • the present invention provides a simple, effective means for overcoming what, to many men, is a major problem and each man can adjust the device to suit his own particular needs.
  • the device can be adjusted to enhance the intensity and/or duration of orgasm to enhance the enjoyment of the sexual act.
  • the side portions 24 may be pressed inwardly e.g. to move the top portion 21 outwardly and away from the penis 10.

Landscapes

  • Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Nursing (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Prostheses (AREA)
  • Percussion Or Vibration Massage (AREA)

Abstract

A therapeutic device (20) for the treatment of male sexual dysfunction which has first and second substantially rigid portions (21, 23) interconnected by malleable or deformable portions (24). The device (20) is fitted to the base of the male penis and by selective deformation of the device (20), the first portion constricts blood flow through the penile veins to enable the user to achieve a penile erection; the second portion (23) constricts the urethra to prevent premature ejaculation; and the malleable or deformable portions (24) constrict blood flow through the penile arteries to overcome Priapism. The device (20) has a core (30) (e.g. of copper wire) within a deformable resilient sheath (33), with grooves or slots (27) which allow blood flow through the blood vessels under the skin of the penis when in use.

Description

TITLE: "THERAPEUTIC DEVICE FOR MALE SEXUAL DYSFUNCTION"
BACKGROUND OF THE INVENTION (1) Field of the Invention:
THIS INVENTION relates to a therapeutic device for male sexual dysfunction. The device may also be used to enhance male sexual pleasure (e.g. by prolonging the male orgasm) . (1) Prior Art:
There are three main problem areas in male sexual dysfunction, as follows:-
(1) the in»ability to achieve and/or maintain penile erection;
(2) Priapism (i.e. where penile erection is not released) ; and (3) premature ejaculation.
There are many reasons for these problems. In certain cases they are related to the side effects of drugs. Males who suffer arterial disease, renal disease and/or diabetes are also likely candidates to suffer such problems.
Various methods have been adopted in an attempt to solve these problems. For example, the problem of penile erection has seen the use of surgery to restore arterial flow and the use of inflatible implants to enable an erection to be achieved. Priapism often requires an injection to enable the erection to be released while desensitizing preparations can be prescribed for premature ejaculation.
All of the proposals to date have problems in themselves and tend to mitigate against any enjoyment obtained from performing the sexual act.
SUMMARY OF THE INVENTION It is an object of the present invention to provide a device which may be used to solve (or reduce) one or more of the problems discussed above. It is a preferred object to provide a device which can be fitted by the user as required.
It is a further preferred object to provide a device which is not obtrusive and which can be easily adjusted by the user to be both effective and comfortable.
It is a still further preferred object that the device will maintain feeling in the skin of the penis. Other preferred objects of the present invention will become apparent from the following description.
In a broad aspect the present invention resides in a therapeutic device for male sexual dysfunction including:- a body having at least one rigid or semi¬ rigid portion and at least one malleable or deformable portion, so arranged that the body may be positioned around the base of a penis to apply a constriction force on at least one portion of the penis.
The body may comprise a closed loop. Alternatively, the body may be substantially C-shaped and the free ends of the body may be releasably engageable. Preferably the body comprises a core within a sheath of deformable material, the sheath preferably being formed of plastics material and may be skin coloured and have a textured finish.
The core may be formed from copper or stainless steel wire or strip, plastics strip or the like. The rigid/semi-rigid portion(s) may be formed by placing a tubular portion about the wire or strip; or winding wire about the wire or strip; or by internal reinforcement or tempering of the wire or strip. The malleable or deformable portion may comprise the wire or strip or a reduced thickness/diameter section of same. Preferably there are two opposed rigid/semi¬ rigid portions, the upper being substantially linear to bear on the top of the base of the penis and the lower of substantially U- or V-shape to span the urethra at the base of the penis.
Preferably the two rigid/semi-rigid portions are interconnected by the malleable/deformable positions, each of which may comprise textured sections to allow blood flow through the blood vessels just below the penile skin.
The textured sections may have diagonal, longitudinal or criss-crossed lines or slots.
The device may be substantially triangular in plan, although circular, oval, square, hexagonal or other shapes may be produced before the user forms the device to the desired shape to suit his needs. The device may be circular or oval in cross-section; or substantially triangular in cross-section, tapering towards the front of the device. BRIEF DESCRIPTION OF THE DRAWINGS
To enable the invention to be fully understood, a preferred embodiment will now be described with reference to the accompanying drawings, in which:- FIG. 1 is a cross-sectional view of a male adult penis;
FIG. 2 is a schematic side view showing the location of the device in use;
FIG. 3 is a front view of the device; FIG. 4 is a sectional front view of the device;
FIGS. 5 to 7 are sectional side views, taken on line A-A on FIG. 4 of alternative cross-sections of the device;
FIGS. 8 and 9 are respective sectional side views of further alternative cross-sections of the device; and FIGS. 10, 11 and 12 are front views of further alternative embodiments of the device.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
Referring to FIG. 1, the male penis 10 has the following areas relevant to the invention: corpora cavernosa 11, penile arteries 12, penile veins 13, urethra 14, corpus spongiosum 15 and skin 16. As shown in FIG. 2, the device 20 is positioned at the base of the penis 10 adjacent the scrotum 17. The device 20, see FIGS. 3 and 4, is generally triangular in front view. The top portion 21 has an enlarged central section 22 opposed to the generally U- or V-shaped bottom portion 23. The two side portions 24 have enlarged sections 25, 26 which have criss-cross slots or grooves 27 (see FIGS. 5 to 7) which allow blood flow through the blood vessels under the skin 16 of the penis 10 when the device 20 is in use. As shown in FIGS. 3 to 5, the central portion 22 has a pair of "lips" 28, 29 which apply spaced pressure to the top of the penis 10.
The device 20 has a core 30 of copper or stainless steel wire which is circular in section 31 in the central section 24 of the top portion and in the bottom portion 23, so arranged that these are rigid or substantially rigid. The remaining portions 32 of the core are flattened to form a thin-section strip which is malleable or deformable so that the shape of the device 20 can be changed as hereinafter described.
The core 30 is enclosed within a deformable plastic sheath 33 which is skin coloured (in a range of skin tones) and have a textured surface or "skin").
The user positions the device as shown in FIG. 2. If the dysfunction to be overcome is the problem of achieving and/or maintaining a penile erection, he deforms the side portion 24 so that the central section 22 (and its lips 28, 29) apply a pressure on the top of the penis 10 to constrict the flow through the penile veins 13 (including the deep Dorsal vein). When the flow through the arteries 12 exceeds the flow through the veins 13, erection will be achieved and maintained. As the bottom portion 23 does not constrict the urethra 14 (see FIG. 10), ejaculation can occur normally.
If the problem is Priapism, the enlarged sections 25, 26 of the side portions 24 are moved inwardly to constrict the arterial blood flow so that the veneous blood flow will enable the penis to become flaccid after erection.
For premature ejaculation, the bottom portion 23 is deformed to apply a constriction on the urethra 14. As blood can flow through the blood vessels under the penile skin 16, penile feeling is not lost.
Referring to FIGS. 5 to 7, the cross-section of the devices 20A, 20B, 20C may be generally rectangulr (FIG. 5), circular or oval (FIG. 6) and triangular or tapered (FIG. 7). The lines or slots on the enlarged sections 25, 26 may be diagonal (27A) or longitudinal (27B).
Referring now to FIG. 8, the device 20D has a substantially right-angled triangular cross-section tapering from a back wall 35 which would engage the user's body 18 and tapering to a "nose" 36 a small distance along the shaft 19 of the penis 10.
In this embodiment, the core 30D is formed by copper or stainless steel wire and the rigid/semi-rigid sectin 31D are formed by winding wire around the core 30D, where the core forms the malleable section 32D.
In the embodiment of FIG. 9, the device 20E has an oval cross-section with a core 30E formed of plastics (e.g. nylon, polyethylene) strip 32E where the enlarged sections 3IE are of increased thickness and may be impregnated with glass reinforcing fibres. FIG. 10 shows an alternative embodiment of the device 20F which does not have the enlarged sections 25, 26 on its side portion 24F and the penis 10 is shown in dashed lines to show how the device can constrict the penile veins 13, while leaving the penile arteries 12 and urethra 14 unconstricted where the user has difficulty achieving and/or maintaining an erection.
FIG. 11 shows a further embodiment of the device 20G which is more circular in front view. FIG. 12 shows a still further embodiment where the device 2OH does not comprise a closed loop but is substantially C-shaped. As indicated by dashed lines 40, 41, the free ends of the device 20H may be releasably secured together to form a closed loop. Onde the user has established the best shape of the device for his needs, e.g. to achieve and maintain an erection without discomfort, he will leave the shape of the deviced fixed and it will be ready for use the next time the sexual act is to be consumated. Because the sheath is preferably skin coloured and textured, it is unobtrusive and a sexual partner may not be aware that it is in place. The device can be easily fitted before the sexual act and removed when no longer required. It's inert material sheath 33 can be easily cleaned between use.
It will be readily apparent to the skilled addresssee that the present invention provides a simple, effective means for overcoming what, to many men, is a major problem and each man can adjust the device to suit his own particular needs.
In addition, the device can be adjusted to enhance the intensity and/or duration of orgasm to enhance the enjoyment of the sexual act.
To release the device, the side portions 24 may be pressed inwardly e.g. to move the top portion 21 outwardly and away from the penis 10. Various changes and modifications may be made to the embodiments described and illustrated without departing from the scope of the present invention defined in the appended claims.

Claims

CLAIMS:
1. A therapeutic device for the treatment of male sexual dysfunction, the device comprising a body to be positioned around the base of the penis, the body including: a first substantially rigid portion opposed to second substantially rigid portion, the first and second substantially rigid portions being interconnected by at least one malleable or deformable portion, so arranged that by selective deformation of the body, the first substantially rigid portion constricts the blood flow through the penile veins, the second substantially rigid portion constricts the urethra, or the malleable or deformable portion or portions constrict the blood flow through the penile arteries, while permitting blood through the blood vessels under the penile skin.
2. A device according to Claim 1 wherein: the body comprises a closed loop; or is substantially C-shaped in front view, the free ends of the body being optionally releasably engageable.
3. A device according to Claim 1 wherein: the body comprises a core within a sheath of deformable material. 4. A device according to Claim 3 wherein: the sheath is formed of skin-coloured plastics material and has a textured finish or "skin".
5. A device according to Claim 1 wherein: the first substantially rigid portion bears on the top of the penis and the second substantially rigid portion spans the urethra at the bottom of the penis, the second substantially rigid portion being substantially U- or V-shaped in front view.
6. A device according to Claim 5 wherein: the two substantially rigid portions are formed of copper or stainless steel wire; copper or stainless steel wire encased in a tube or around which wire is wound; or an enlarged section of glass-fibre- reinforced plastics.
7. A device according to Claim 1 wherein: the malleable or deformable portion or portions of the core are formed of copper or stainless steel wire or strip; or plastics-material wire or strip.
8. A device according to Claim 1 wherein: the sheath has one or more portions of increased thickness and at least one of these portions has a pair of lips to bear on the shaft of the penis and/or slots or grooves to enable blood flow through the blood vessels under the skin of the penis.
EP19900909436 1989-06-29 1990-06-27 Therapeutic device for male sexual dysfunction Withdrawn EP0479825A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU37147/89A AU626135B2 (en) 1989-06-29 1989-06-29 Therapeutic device for male sexual dysfunction
AU37147/89 1989-06-29

Publications (2)

Publication Number Publication Date
EP0479825A1 EP0479825A1 (en) 1992-04-15
EP0479825A4 true EP0479825A4 (en) 1992-10-28

Family

ID=3724304

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900909436 Withdrawn EP0479825A4 (en) 1989-06-29 1990-06-27 Therapeutic device for male sexual dysfunction

Country Status (17)

Country Link
EP (1) EP0479825A4 (en)
JP (1) JPH05501067A (en)
KR (1) KR920702612A (en)
CN (1) CN1022978C (en)
AR (1) AR244073A1 (en)
AU (1) AU626135B2 (en)
BR (1) BR9007484A (en)
CA (1) CA2062817A1 (en)
CS (1) CS324690A3 (en)
DD (1) DD296206A5 (en)
FI (1) FI916133A0 (en)
IE (1) IE902356A1 (en)
NO (1) NO915121L (en)
PL (1) PL164410B1 (en)
WO (1) WO1991000073A1 (en)
YU (1) YU127590A (en)
ZA (1) ZA904970B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4129177C1 (en) * 1991-09-03 1992-08-27 Albert G. Prof. Dr. 4600 Dortmund De Fischer
GB2301536A (en) * 1995-06-02 1996-12-11 Yee Man Liu Supportive and/or pressure-applying device for a body part
DE19604465C2 (en) * 1996-02-08 2003-12-11 Crivellaro Juergen Cockring
FR2772260B1 (en) * 1997-10-27 2000-03-31 Pierre Dukan ERECTILE RING OF ORCHARD
CZ299051B6 (en) * 2004-03-16 2008-04-09 Saglena@Jan Erectile function gauge

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US2581114A (en) * 1950-04-13 1952-01-01 Leroy J Larson Surgical device
US3636948A (en) * 1970-05-07 1972-01-25 Otto Atchley Therapeutic device
US3705580A (en) * 1971-07-19 1972-12-12 Oscar Gauthier Device for medical use
US4203432A (en) * 1978-12-04 1980-05-20 Koch Edward G Male therapeutic device

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GB734394A (en) * 1953-09-14 1955-07-27 Marco Ivanov Mantchev Improvements in or relating to medical appliances
US2818855A (en) * 1954-02-11 1958-01-07 Anthony P Miller Surgical device
US3511230A (en) * 1968-04-19 1970-05-12 Paul B Strong Copulation aid
US3794020A (en) * 1972-06-16 1974-02-26 R Bagby Anatomical device
AT349606B (en) * 1975-04-14 1979-04-10 Erwin Butt DEVICE AGAINST MALE IMPOTENCE
US4474187A (en) * 1981-11-05 1984-10-02 Dacomed Corporation Threshold penile rigidity measuring device
AU6541186A (en) * 1986-09-18 1988-04-07 Companion Medical Products Corp. External penile support device and method

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
US2581114A (en) * 1950-04-13 1952-01-01 Leroy J Larson Surgical device
US3636948A (en) * 1970-05-07 1972-01-25 Otto Atchley Therapeutic device
US3705580A (en) * 1971-07-19 1972-12-12 Oscar Gauthier Device for medical use
US4203432A (en) * 1978-12-04 1980-05-20 Koch Edward G Male therapeutic device

Non-Patent Citations (1)

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Title
See also references of WO9100073A1 *

Also Published As

Publication number Publication date
CS324690A3 (en) 1992-04-15
AU3714789A (en) 1991-05-16
BR9007484A (en) 1992-06-16
NO915121D0 (en) 1991-12-27
JPH05501067A (en) 1993-03-04
CN1022978C (en) 1993-12-08
PL164410B1 (en) 1994-07-29
NO915121L (en) 1992-02-27
ZA904970B (en) 1991-04-24
IE902356L (en) 1990-12-29
DD296206A5 (en) 1991-11-28
EP0479825A1 (en) 1992-04-15
IE902356A1 (en) 1991-02-13
KR920702612A (en) 1992-10-06
FI916133A0 (en) 1991-12-27
WO1991000073A1 (en) 1991-01-10
CN1048797A (en) 1991-01-30
AR244073A1 (en) 1993-10-29
PL285854A1 (en) 1991-03-11
YU127590A (en) 1994-04-05
AU626135B2 (en) 1992-07-23
CA2062817A1 (en) 1990-12-30

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