EE03608B1 - Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid - Google Patents

Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid

Info

Publication number
EE03608B1
EE03608B1 EE9700315A EE9700315A EE03608B1 EE 03608 B1 EE03608 B1 EE 03608B1 EE 9700315 A EE9700315 A EE 9700315A EE 9700315 A EE9700315 A EE 9700315A EE 03608 B1 EE03608 B1 EE 03608B1
Authority
EE
Estonia
Prior art keywords
taxoids
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
EE9700315A
Other languages
English (en)
Other versions
EE9700315A (et
Inventor
Bouchard Herv
Bourzat Jean-Dominique
Commer�on Alain
Original Assignee
Rh�Ne-Poulenc Rorer S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9503545A external-priority patent/FR2732340B1/fr
Priority claimed from FR9515381A external-priority patent/FR2742754B1/fr
Application filed by Rh�Ne-Poulenc Rorer S.A. filed Critical Rh�Ne-Poulenc Rorer S.A.
Publication of EE9700315A publication Critical patent/EE9700315A/et
Publication of EE03608B1 publication Critical patent/EE03608B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EE9700315A 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid EE03608B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9503545A FR2732340B1 (fr) 1995-03-27 1995-03-27 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR9515381A FR2742754B1 (fr) 1995-12-22 1995-12-22 Procede de preparation de taxoides
PCT/FR1996/000440 WO1996030355A1 (fr) 1995-03-27 1996-03-25 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
EE9700315A EE9700315A (et) 1998-06-15
EE03608B1 true EE03608B1 (et) 2002-02-15

Family

ID=26231838

Family Applications (2)

Application Number Title Priority Date Filing Date
EE9700315A EE03608B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid
EE9700323A EE03609B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid

Family Applications After (1)

Application Number Title Priority Date Filing Date
EE9700323A EE03609B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid

Country Status (41)

Country Link
US (3) US5889043A (et)
EP (2) EP0817780B1 (et)
JP (2) JP2941951B2 (et)
KR (2) KR100485309B1 (et)
CN (2) CN1213042C (et)
AP (2) AP785A (et)
AR (1) AR001440A1 (et)
AT (2) ATE188471T1 (et)
AU (2) AU703278B2 (et)
BG (2) BG63009B1 (et)
BR (2) BR9607929A (et)
CA (2) CA2214319C (et)
CO (1) CO4700576A1 (et)
CZ (2) CZ287326B6 (et)
DE (2) DE69604653T2 (et)
DK (2) DK0817780T3 (et)
DZ (1) DZ2009A1 (et)
EA (2) EA000709B1 (et)
EE (2) EE03608B1 (et)
ES (2) ES2143187T3 (et)
GE (2) GEP20002188B (et)
GR (2) GR3031526T3 (et)
HU (2) HU223732B1 (et)
IL (1) IL117636A (et)
IS (2) IS2058B (et)
MA (1) MA23823A1 (et)
MY (1) MY121225A (et)
NO (2) NO316379B1 (et)
NZ (2) NZ304901A (et)
OA (2) OA10514A (et)
PE (1) PE51097A1 (et)
PL (2) PL188284B1 (et)
PT (1) PT817779E (et)
RO (2) RO115877B1 (et)
SK (2) SK281928B6 (et)
TN (1) TNSN96043A1 (et)
TR (2) TR199701040T1 (et)
TW (1) TW394765B (et)
UY (2) UY24192A1 (et)
WO (2) WO1996030355A1 (et)
ZA (1) ZA962399B (et)

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US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US5811452A (en) * 1997-01-08 1998-09-22 The Research Foundation Of State University Of New York Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
FR2771092B1 (fr) * 1997-11-18 1999-12-17 Rhone Poulenc Rorer Sa Procede de preparation de derives de la classe des taxoides
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US6346543B1 (en) * 1998-08-17 2002-02-12 Aventis Pharma S.A. Use of a taxoid to treat abnormal cell proliferation in the brain
EP0982028A1 (en) * 1998-08-20 2000-03-01 Aventis Pharma S.A. New use of taxoid derivatives
AU5742099A (en) * 1998-08-20 2000-03-14 Aventis Pharma S.A. New use of taxoid derivatives
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US6649632B2 (en) * 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CN1362876A (zh) * 2000-02-02 2002-08-07 佛罗里达州立大学研究基金有限公司 C10杂取代的乙酸基紫衫烷抗肿瘤剂
US8147816B2 (en) * 2000-08-16 2012-04-03 Encore Health, Llc Presbyopia treatment by lens alteration
AU2001290636A1 (en) * 2000-09-22 2002-04-02 Bristol-Myers Squibb Company Method for reducing toxicity of combined chemotherapies
CZ2003837A3 (cs) 2000-09-22 2004-12-15 Bristol-Myers Squibb Company Způsob pro snížení toxicity při kombinovaných chemoterapiích
US6593334B1 (en) 2002-05-02 2003-07-15 The University Of North Carolina At Chapel Hill Camptothecin-taxoid conjugates as antimitotic and antitumor agents
EP1534340B1 (en) 2002-09-06 2011-11-16 Cerulean Pharma Inc. Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto
WO2004043390A2 (en) * 2002-11-08 2004-05-27 Bristol-Myers Squibb Company Pharmaceutical compositions and methods of using taxane derivatives
EP1663153A4 (en) * 2003-05-20 2011-01-05 Aronex Pharmaceuticals Inc COMBINATION SCHEMOTHERAPY WITH A LIPOSOMAL PLATINUM COMPLEX
US7064980B2 (en) * 2003-09-17 2006-06-20 Sandisk Corporation Non-volatile memory and method with bit line coupled compensation
FR2859996B1 (fr) 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
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SV2006002010A (es) * 2004-02-13 2006-08-23 Univ Florida State Res Found Taxanos sustituidos con esteres de ciclopentilo en c10
CA2597682A1 (en) * 2005-02-14 2006-08-24 Florida State University Research Foundation, Inc. C10 cyclopropyl ester substituted taxane compositions
EP1871753B1 (en) * 2005-03-31 2012-07-18 Accord Healthcare Inc. Preparation of taxanes from 9-dihydro-13-acetylbaccatin iii
DK1948669T3 (da) * 2005-11-04 2013-10-07 Accord Healthcare Inc Nye fremgangsmåder til fremstiling af taxaner under anvendelse af chirale hjælpestoffer
US7847111B2 (en) * 2006-06-19 2010-12-07 Canada Inc. Semi-synthetic route for the preparation of paclitaxel, docetaxel, and 10-deacetylbaccatin III from 9-dihydro-13-acetylbaccatin III
US20080176958A1 (en) 2007-01-24 2008-07-24 Insert Therapeutics, Inc. Cyclodextrin-based polymers for therapeutics delivery
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PE20121429A1 (es) 2009-10-29 2012-11-06 Aventis Pharma Sa Nuevo uso antitumoral de cabazitaxel
CN104208716A (zh) * 2009-11-23 2014-12-17 天蓝制药公司 用于传递治疗剂的基于环糊精的聚合物
US8791279B2 (en) * 2010-12-13 2014-07-29 Yung Shin Pharm. Ind. Co., Ltd. Process for preparing taxoids from baccatin derivatives using lewis acid catalyst
US20130338216A1 (en) 2010-12-22 2013-12-19 Nektar Therapeutics Deuterated and/or fluorinated taxane derivatives
US10894087B2 (en) 2010-12-22 2021-01-19 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
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TWI526437B (zh) 2011-09-09 2016-03-21 台灣神隆股份有限公司 卡巴他賽之結晶型
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CN102336726B (zh) * 2011-09-30 2014-11-26 重庆泰濠制药有限公司 一种卡巴他赛的制备方法
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CN102408397B (zh) 2011-10-19 2014-08-20 上海贝美医药科技有限公司 紫杉烷类衍生物及其制备方法
CN102603724B (zh) * 2011-10-20 2014-02-26 江苏红豆杉生物科技股份有限公司 二甲氧基紫杉烷类化合物纯化精制的方法
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CN102516281B (zh) * 2011-10-20 2015-02-04 江苏红豆杉生物科技股份有限公司 一种10-脱乙酰基巴卡丁iii及其衍生物甲氧基化的方法
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CN103159705B (zh) * 2011-12-12 2015-05-27 福建南方制药股份有限公司 卡巴他赛中间体的制备方法
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CN104650012A (zh) * 2013-11-22 2015-05-27 天士力控股集团有限公司 一种紫杉烷类化合物
CN104086514A (zh) * 2014-06-19 2014-10-08 上海应用技术学院 紫杉醇衍生物及其制备方法
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Also Published As

Publication number Publication date
US6331635B1 (en) 2001-12-18
HUP9801201A3 (en) 2000-12-28
BG101918A (en) 1998-10-30
NO316607B1 (no) 2004-03-08
MY121225A (en) 2006-01-28
PE51097A1 (es) 1997-12-22
CA2214321C (fr) 2008-01-22
CN1152870C (zh) 2004-06-09
RO115877B1 (ro) 2000-07-28
AR001440A1 (es) 1997-10-22
HU223666B1 (hu) 2004-11-29
CZ287326B6 (en) 2000-10-11
EE03609B1 (et) 2002-02-15
IL117636A (en) 2004-08-31
ES2143187T3 (es) 2000-05-01
IS2056B (is) 2005-10-14
EP0817780A1 (fr) 1998-01-14
EP0817779B1 (fr) 2000-01-05
ATE188471T1 (de) 2000-01-15
JP3790826B2 (ja) 2006-06-28
NZ304901A (en) 1998-12-23
MA23823A1 (fr) 1996-10-01
AP753A (en) 1999-07-21
CA2214319A1 (fr) 1996-10-03
WO1996030355A1 (fr) 1996-10-03
DE69604653T2 (de) 2000-05-31
CA2214319C (fr) 2004-02-17
GEP20002211B (en) 2000-08-25
DE69604653D1 (de) 1999-11-18
CA2214321A1 (fr) 1996-10-03
TR199701042T1 (xx) 1998-01-21
HUP9801201A2 (hu) 2000-05-28
MX9706278A (es) 1997-10-31
KR19980703357A (ko) 1998-10-15
AP9701093A0 (en) 1997-10-31
KR100485309B1 (ko) 2005-10-12
HUP9801204A1 (hu) 2000-05-28
DE69606028T2 (de) 2000-08-10
JP2941951B2 (ja) 1999-08-30
EA199700270A1 (ru) 1998-02-26
NO316379B1 (no) 2004-01-19
ES2140075T3 (es) 2000-02-16
SK130297A3 (en) 1998-03-04
SK130197A3 (en) 1998-04-08
EA199700269A1 (ru) 1998-04-30
GEP20002188B (en) 2000-07-25
TW394765B (en) 2000-06-21
PT817779E (pt) 2000-04-28
EE9700315A (et) 1998-06-15
CZ303297A3 (cs) 1998-01-14
IS4567A (is) 1997-09-23
SK281927B6 (sk) 2001-09-11
EP0817779A1 (fr) 1998-01-14
CN1179776A (zh) 1998-04-22
BG63009B1 (bg) 2001-01-31
GR3031526T3 (en) 2000-01-31
ATE185562T1 (de) 1999-10-15
NO973922L (no) 1997-08-26
AP9701090A0 (en) 1997-10-31
PL322499A1 (en) 1998-02-02
IS4536A (is) 1997-07-31
KR19980703287A (ko) 1998-10-15
PL188284B1 (pl) 2005-01-31
CO4700576A1 (es) 1998-12-29
US20020038038A1 (en) 2002-03-28
SK281928B6 (sk) 2001-09-11
PL188987B1 (pl) 2005-05-31
US6387946B1 (en) 2002-05-14
EA000709B1 (ru) 2000-02-28
IL117636A0 (en) 1996-07-23
DK0817779T3 (da) 2000-06-19
AU711227B2 (en) 1999-10-07
EP0817780B1 (fr) 1999-10-13
BR9607929A (pt) 1998-06-02
DZ2009A1 (fr) 2002-10-23
MX9706568A (es) 1997-11-29
HU223732B1 (hu) 2004-12-28
UY24370A1 (es) 2001-10-25
US5889043A (en) 1999-03-30
EE9700323A (et) 1998-06-15
BG63121B1 (bg) 2001-04-30
DE69606028D1 (de) 2000-02-10
WO1996030356A1 (fr) 1996-10-03
AU5278196A (en) 1996-10-16
JPH11500141A (ja) 1999-01-06
UY24192A1 (es) 1996-06-14
KR100297196B1 (ko) 2001-11-22
BG101917A (en) 1998-10-30
AU5278096A (en) 1996-10-16
DK0817780T3 (da) 2000-03-27
ZA962399B (en) 1996-10-01
RO115878B1 (ro) 2000-07-28
AU703278B2 (en) 1999-03-25
GR3032316T3 (en) 2000-04-27
PL322465A1 (en) 1998-02-02
CN1213042C (zh) 2005-08-03
BR9607930A (pt) 1998-06-02
TNSN96043A1 (fr) 2005-03-15
NO973922D0 (no) 1997-08-26
CZ287468B6 (en) 2000-12-13
CN1179775A (zh) 1998-04-22
AP785A (en) 1999-11-26
EA000567B1 (ru) 1999-12-29
NO973923D0 (no) 1997-08-26
NZ304900A (en) 1998-09-24
IS2058B (is) 2005-10-14
CZ303097A3 (cs) 1998-01-14
TR199701040T1 (xx) 1998-01-21
JPH11502531A (ja) 1999-03-02
NO973923L (no) 1997-08-26
OA10514A (fr) 2002-04-22
HUP9801204A3 (en) 2000-12-28
OA10513A (fr) 2002-04-22

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