ECSP088288A - DERIVADOS DE 7-(2-AMINO-1-HIDROXI-ETIL)-4-HIDROXIBENZOTIAZOL-2(3H)-ONA COMO AGONISTAS DE LOS ADRENOCEPTORES ß2 - Google Patents

DERIVADOS DE 7-(2-AMINO-1-HIDROXI-ETIL)-4-HIDROXIBENZOTIAZOL-2(3H)-ONA COMO AGONISTAS DE LOS ADRENOCEPTORES ß2

Info

Publication number
ECSP088288A
ECSP088288A EC2008008288A ECSP088288A ECSP088288A EC SP088288 A ECSP088288 A EC SP088288A EC 2008008288 A EC2008008288 A EC 2008008288A EC SP088288 A ECSP088288 A EC SP088288A EC SP088288 A ECSP088288 A EC SP088288A
Authority
EC
Ecuador
Prior art keywords
hydroxibenzotiazol
hidroxi
etil
adrenoceptors
ona
Prior art date
Application number
EC2008008288A
Other languages
English (en)
Inventor
Andrew Bailey
Roger Bonnert
Stephen Connolly
Anthony Ingall
Garry Pairaudeau
Michael Stocks
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ECSP088288A publication Critical patent/ECSP088288A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • AIDS & HIV (AREA)
  • Pregnancy & Childbirth (AREA)
  • Tropical Medicine & Parasitology (AREA)

Abstract

La presente invención provee compuestos de la fórmula (I), en donde las variables tienen las definiciones indicadas en la descripción, procesos para su preparación, composiciones farmacéuticas que los contienen y su uso en terapia.
EC2008008288A 2005-08-29 2008-03-17 DERIVADOS DE 7-(2-AMINO-1-HIDROXI-ETIL)-4-HIDROXIBENZOTIAZOL-2(3H)-ONA COMO AGONISTAS DE LOS ADRENOCEPTORES ß2 ECSP088288A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0501905 2005-08-29
SE0601331 2006-06-15

Publications (1)

Publication Number Publication Date
ECSP088288A true ECSP088288A (es) 2008-04-28

Family

ID=37809142

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008288A ECSP088288A (es) 2005-08-29 2008-03-17 DERIVADOS DE 7-(2-AMINO-1-HIDROXI-ETIL)-4-HIDROXIBENZOTIAZOL-2(3H)-ONA COMO AGONISTAS DE LOS ADRENOCEPTORES ß2

Country Status (15)

Country Link
US (1) US20090221653A1 (es)
EP (1) EP1937656A4 (es)
JP (1) JP2009507788A (es)
KR (1) KR20080038373A (es)
AR (1) AR055401A1 (es)
AU (1) AU2006285448A1 (es)
BR (1) BRPI0615101A2 (es)
CA (1) CA2620466A1 (es)
EC (1) ECSP088288A (es)
IL (1) IL189434A0 (es)
NO (1) NO20081479L (es)
RU (1) RU2406723C9 (es)
TW (1) TW200738659A (es)
UY (1) UY29767A1 (es)
WO (1) WO2007027134A1 (es)

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Publication number Priority date Publication date Assignee Title
TW200738658A (en) * 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
JP5040261B2 (ja) * 2006-09-28 2012-10-03 東洋紡績株式会社 （置換プロピルスルファニル）−アルキルアルコールの製造方法
TW200825084A (en) 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
TW200833670A (en) 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
GB0704000D0 (en) * 2007-03-01 2007-04-11 Astrazeneca Ab Salts 670
GB0703999D0 (en) * 2007-03-01 2007-04-11 Astrazeneca Ab New combination 667
WO2009037503A2 (en) * 2007-09-18 2009-03-26 Astrazeneca Ab New combination - 012 for the treatment of respiratory diseases
CN102083839B (zh) 2008-02-06 2014-03-26 阿斯利康(瑞典)有限公司 化合物
JP2011520877A (ja) * 2008-05-13 2011-07-21 アストラゼネカ・アクチエボラーグ ムスカリン受容体アンタゴニストおよびβ２−アドレナリン受容体アゴニストを含む医薬品
EA017627B1 (ru) 2008-05-13 2013-01-30 Астразенека Аб Хинуклидиновые производные в качестве антагонистов мускаринового м3 рецептора
WO2009142568A1 (en) * 2008-05-20 2009-11-26 Astrazeneca Ab Combination of (a) glucocorticoid receptor modulator and (b) a b2-agonist
KR20110017456A (ko) 2008-06-18 2011-02-21 아스트라제네카 아베 호흡기 장애의 치료를 위한 베타2-아드레날린성 수용체 효능제로서 작용하는 벤족사지논 유도체
EP2303266A4 (en) * 2008-06-20 2015-01-21 Astrazeneca Ab PHARMACEUTICAL COMPOSITION COMPRISING A 4-HYDROXY-2-OXO-2,3-DIHYDRO-1,3-BENZOTHIAZOL-7-YLE COMPOUND FOR THE MODULATION OF BETA-2-ADRENORECEPTOR ACTIVITY
GB0814728D0 (en) * 2008-08-12 2008-09-17 Argenta Discovery Ltd New combination
GB0913342D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab Compounds - 801
GB0913345D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab New combination 802
GB201107985D0 (en) 2011-05-13 2011-06-29 Astrazeneca Ab Process
JO3192B1 (ar) 2011-09-06 2018-03-08 Novartis Ag مركب بنزوثيازولون

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UY29767A1 (es) 2007-03-30
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