EA200000956A1 - Фармацевтический аэрозольный препарат - Google Patents

Фармацевтический аэрозольный препарат

Info

Publication number
EA200000956A1
EA200000956A1 EA200000956A EA200000956A EA200000956A1 EA 200000956 A1 EA200000956 A1 EA 200000956A1 EA 200000956 A EA200000956 A EA 200000956A EA 200000956 A EA200000956 A EA 200000956A EA 200000956 A1 EA200000956 A1 EA 200000956A1
Authority
EA
Eurasian Patent Office
Prior art keywords
preparations
aerosol product
pharmaceutical aerosol
therapeutic agent
new
Prior art date
Application number
EA200000956A
Other languages
English (en)
Inventor
Паскаль Кавайон
Натали Ллорка
Оливье Луи
Патрик Розье
Original Assignee
Глаксо Груп Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9808152.4A external-priority patent/GB9808152D0/en
Priority claimed from GBGB9814709.3A external-priority patent/GB9814709D0/en
Application filed by Глаксо Груп Лимитед filed Critical Глаксо Груп Лимитед
Publication of EA200000956A1 publication Critical patent/EA200000956A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Настоящее изобретение относится к новым аэрозольным препаратам, содержащим: (А) терапевтический агент в форме частиц, покрытых, по меньшей мере, одним покровным эксципиентом и, по меньшей мере, одним поверхностно-активным веществом, в виде суспензии в (Б) сжиженном газе-пропелленте, для введения терапевтического агента, в частности легочным путем, и к способу изготовления этих препаратов. Оно также относится к новым частицам, пригодным для использования в таких препаратах.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200000956A 1998-04-18 1999-04-15 Фармацевтический аэрозольный препарат EA200000956A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9808152.4A GB9808152D0 (en) 1998-04-18 1998-04-18 Pharmaceutical aerosol formulation
GBGB9814709.3A GB9814709D0 (en) 1998-07-08 1998-07-08 Pharmaceutical aerosol formulation
PCT/EP1999/002535 WO1999053901A1 (en) 1998-04-18 1999-04-15 Pharmaceutical aerosol formulation

Publications (1)

Publication Number Publication Date
EA200000956A1 true EA200000956A1 (ru) 2001-04-23

Family

ID=26313483

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200000956A EA200000956A1 (ru) 1998-04-18 1999-04-15 Фармацевтический аэрозольный препарат

Country Status (30)

Country Link
US (1) US7521042B2 (ru)
EP (1) EP1073417B1 (ru)
JP (1) JP2002512183A (ru)
KR (1) KR20010042816A (ru)
CN (1) CN1145478C (ru)
AP (1) AP2000001961A0 (ru)
AR (1) AR018183A1 (ru)
AT (1) ATE228823T1 (ru)
AU (1) AU755066B2 (ru)
BR (1) BR9909736A (ru)
CA (1) CA2328882A1 (ru)
CO (1) CO5021210A1 (ru)
DE (1) DE69904312T2 (ru)
DK (1) DK1073417T3 (ru)
EA (1) EA200000956A1 (ru)
EE (1) EE200000608A (ru)
ES (1) ES2189410T3 (ru)
HR (1) HRP20000689A2 (ru)
HU (1) HUP0101608A2 (ru)
ID (1) ID27887A (ru)
IL (1) IL139087A0 (ru)
IS (1) IS5665A (ru)
MA (1) MA26621A1 (ru)
NO (1) NO20005218L (ru)
NZ (1) NZ507619A (ru)
PE (1) PE20000433A1 (ru)
PL (1) PL343491A1 (ru)
PT (1) PT1073417E (ru)
TR (1) TR200100144T2 (ru)
WO (1) WO1999053901A1 (ru)

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US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
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TWI341836B (en) 2004-03-11 2011-05-11 Theravance Inc Biphenyl compounds useful as muscarinic receptor antagonists
EP1833822A2 (en) 2004-08-16 2007-09-19 Theravance, Inc. Compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity
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JP5508003B2 (ja) 2006-06-30 2014-05-28 アイスイティカ ピーティーワイ リミテッド ナノ粒子状の形態における生物学的に活性な化合物の調製のための方法
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WO2010091198A1 (en) 2009-02-06 2010-08-12 University Of Southern California Therapeutic compositions comprising monoterpenes
HUE045917T2 (hu) 2009-02-26 2020-01-28 Glaxo Group Ltd 4-{(lR)-2-[(6-(2-[(2,6-Diklórbenzil)-oxi}-etoxi}-hexil)-amino]-l-hidroxietil}-2-(hidroximetil)-fenolt tartalmazó gyógyszerkészítmények
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GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
BR112012022209A2 (pt) 2010-03-03 2017-06-06 Neonc Tech Inc composições farmacêuticas compreendendo monoterpenos
CN102933204A (zh) 2010-06-08 2013-02-13 学校法人神户学院 涂覆粒子及涂覆粒子的制造方法
EP3685835A1 (en) 2010-08-27 2020-07-29 Neonc Technologies, Inc. Pharmaceutical compositions comprising poh derivatives
US20160038600A1 (en) 2012-08-03 2016-02-11 Neonc Technologies Inc. Pharmaceutical compositions comprising poh derivatives
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CN102366405A (zh) * 2011-10-21 2012-03-07 江阴长风医药科技有限公司 以氢氟烷烃为抛射剂的氟替卡松丙酸酯气雾剂制剂
CN107875127A (zh) * 2012-02-28 2018-04-06 艾塞尤提卡控股公司 可吸入药物组合物
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Also Published As

Publication number Publication date
IL139087A0 (en) 2001-11-25
AR018183A1 (es) 2001-10-31
ATE228823T1 (de) 2002-12-15
ID27887A (id) 2001-05-03
EP1073417A1 (en) 2001-02-07
JP2002512183A (ja) 2002-04-23
NZ507619A (en) 2003-05-30
WO1999053901A1 (en) 1999-10-28
TR200100144T2 (tr) 2001-06-21
KR20010042816A (ko) 2001-05-25
CN1145478C (zh) 2004-04-14
AP2000001961A0 (en) 2000-12-31
CN1305369A (zh) 2001-07-25
NO20005218L (no) 2000-11-10
PL343491A1 (en) 2001-08-27
CA2328882A1 (en) 1999-10-28
PE20000433A1 (es) 2000-05-26
AU3523199A (en) 1999-11-08
US20030157032A1 (en) 2003-08-21
NO20005218D0 (no) 2000-10-17
CO5021210A1 (es) 2001-03-27
DE69904312D1 (de) 2003-01-16
DK1073417T3 (da) 2003-03-24
ES2189410T3 (es) 2003-07-01
DE69904312T2 (de) 2003-10-16
HUP0101608A2 (hu) 2002-03-28
IS5665A (is) 2000-10-13
MA26621A1 (fr) 2004-12-20
BR9909736A (pt) 2000-12-19
US7521042B2 (en) 2009-04-21
EP1073417B1 (en) 2002-12-04
PT1073417E (pt) 2003-04-30
AU755066B2 (en) 2002-12-05
EE200000608A (et) 2001-08-15
HRP20000689A2 (en) 2001-02-28

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